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Gene: SPINK4 (serine peptidase inhibitor Kazal type 4) Homo sapiens
Symbol: SPINK4
Name: serine peptidase inhibitor Kazal type 4
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity and response to drug. Predicted to localize to the extracellular region; INTERACTS WITH 17beta-estradiol; 5-fluorouracil; butanal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: epididymis luminal protein 136; gastrointestinal peptide; HEL136; MGC133107; PEC-60; PEC60; peptide PEC-60 homolog; serine peptidase inhibitor, Kazal type 4; serine protease inhibitor Kazal-type 4; serine protease inhibitor, Kazal type 4
Mus musculus (house mouse) : Spink4 (serine peptidase inhibitor, Kazal type 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Spink4 (serine peptidase inhibitor, Kazal type 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spink4 (serine peptidase inhibitor Kazal type 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SPINK4 (serine peptidase inhibitor Kazal type 4)
Canis lupus familiaris (dog) : SPINK4 (serine peptidase inhibitor, Kazal type 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spink4 (serine peptidase inhibitor Kazal type 4)
Sus scrofa (pig) : SPINK4 (serine peptidase inhibitor Kazal type 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38933,240,167 - 33,248,567 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37933,240,196 - 33,248,565 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,230,196 - 33,238,565 (+)NCBINCBI36hg18NCBI36
Build 34933,230,195 - 33,238,564NCBI
Celera933,170,395 - 33,178,768 (+)NCBI
Cytogenetic Map9p13.3NCBI
HuRef933,197,153 - 33,205,532 (+)NCBIHuRef
CHM1_1933,239,128 - 33,247,497 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SPINK4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1342974
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.