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Gene: PI4KB (phosphatidylinositol 4-kinase beta) Homo sapiens
Symbol: PI4KB
Name: phosphatidylinositol 4-kinase beta
Description: Exhibits 1-phosphatidylinositol 4-kinase activity and 14-3-3 protein binding activity. Predicted to be involved in phosphatidylinositol phosphorylation and phosphatidylinositol-mediated signaling. Localizes to Golgi membrane; PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH (+)-catechin; 3-isobutyl-1-methyl-7H-xanthine; 5-fluorouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686O1820; FLJ30129; NPIK; phosphatidylinositol 4-kinase; phosphatidylinositol 4-kinase, catalytic, beta; phosphatidylinositol 4-kinase, wortmannin-sensitive; PI4K-BETA; PI4K92; PI4KBETA; PI4KIII; PI4KIIIBETA; PIK4CB; PtdIns 4-kinase beta; type III phosphatidylinositol 4-kinase beta
Mus musculus (house mouse) : Pi4kb (phosphatidylinositol 4-kinase beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pi4kb (phosphatidylinositol 4-kinase beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pi4kb (phosphatidylinositol 4-kinase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : PI4KB (phosphatidylinositol 4-kinase beta)
Canis lupus familiaris (dog) : PI4KB (phosphatidylinositol 4-kinase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pi4kb (phosphatidylinositol 4-kinase beta)
Sus scrofa (pig) : PI4KB (phosphatidylinositol 4-kinase beta)
Chlorocebus sabaeus (African green monkey) : PI4KB (phosphatidylinositol 4-kinase beta)
Heterocephalus glaber (naked mole-rat) : Pi4kb (phosphatidylinositol 4-kinase beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1151,291,797 - 151,327,715 (-)EnsemblGRCh38hg38GRCh38
GRCh381151,291,797 - 151,327,715 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371151,264,273 - 151,300,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,531,037 - 149,565,348 (-)NCBINCBI36hg18NCBI36
Build 341148,077,485 - 148,111,797NCBI
Celera1124,379,704 - 124,414,015 (-)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1122,642,216 - 122,678,133 (-)NCBIHuRef
CHM1_11152,660,019 - 152,695,935 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PI4KB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732673
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.