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Gene: AATK (apoptosis associated tyrosine kinase) Homo sapiens
Symbol: AATK
Name: apoptosis associated tyrosine kinase
Description: The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AATYK; AATYK1; apoptosis-associated tyrosine kinase; brain apoptosis-associated tyrosine kinase; CDK5-binding protein; KIAA0641; lemur tyrosine kinase 1; LMR1; LMTK1; p35-binding protein; p35BP; PPP1R77; serine/threonine-protein kinase LMTK1
Mus musculus (house mouse) : Aatk (apoptosis-associated tyrosine kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aatk (apoptosis-associated tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aatk (apoptosis associated tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : AATK (apoptosis associated tyrosine kinase)
Canis lupus familiaris (dog) : AATK (apoptosis associated tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aatk (apoptosis associated tyrosine kinase)
Sus scrofa (pig) : AATK (apoptosis associated tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381781,117,295 - 81,166,221 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371779,084,285 - 79,139,877 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361776,705,160 - 76,721,740 (-)NCBINCBI36hg18NCBI36
Cytogenetic Map17q25.3NCBI
HuRef1774,530,736 - 74,575,558 (-)NCBIHuRef
CHM1_11779,177,354 - 79,226,085 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AATK
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317702
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.