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Gene: AATK (apoptosis associated tyrosine kinase) Homo sapiens
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Symbol: AATK
Name: apoptosis associated tyrosine kinase
Description: The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AATYK; AATYK1; apoptosis-associated tyrosine kinase; brain apoptosis-associated tyrosine kinase; CDK5-binding protein; KIAA0641; lemur tyrosine kinase 1; LMR1; LMTK1; p35-binding protein; p35BP; PPP1R77; serine/threonine-protein kinase LMTK1
Orthologs:
Mus musculus (house mouse) : Aatk (apoptosis-associated tyrosine kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aatk (apoptosis-associated tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aatk (apoptosis associated tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : AATK (apoptosis associated tyrosine kinase)
Canis lupus familiaris (dog) : AATK (apoptosis associated tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aatk (apoptosis associated tyrosine kinase)
Sus scrofa (pig) : AATK (apoptosis associated tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,117,295 - 81,166,221 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371779,084,285 - 79,139,877 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361776,705,160 - 76,721,740 (-)NCBINCBI36hg18NCBI36
Cytogenetic Map17q25.3NCBI
HuRef1774,530,736 - 74,575,558 (-)NCBIHuRef
CHM1_11779,177,354 - 79,226,085 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on AATK
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317702
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.