SLC13A2 (solute carrier family 13 member 2) - Rat Genome Database

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Gene: SLC13A2 (solute carrier family 13 member 2) Homo sapiens
Analyze
Symbol: SLC13A2
Name: solute carrier family 13 member 2
RGD ID: 736607
HGNC Page HGNC
Description: Enables succinate transmembrane transporter activity. Involved in succinate transmembrane transport. Located in extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Na(+)-coupled citrate transporter; Na(+)/dicarboxylate cotransporter 1; NaCT; NaDC-1; NADC1; renal sodium/dicarboxylate cotransporter; SDCT1; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1728,473,293 - 28,497,781 (+)EnsemblGRCh38hg38GRCh38
GRCh381728,473,357 - 28,497,781 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371726,800,662 - 26,824,799 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,824,791 - 23,848,514 (+)NCBINCBI36hg18NCBI36
Build 341723,824,790 - 23,848,514NCBI
Celera1723,659,792 - 23,683,926 (+)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1723,009,855 - 23,034,040 (+)NCBIHuRef
CHM1_11726,864,116 - 26,888,251 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (ISO)
aflatoxin B1  (EXP)
antirheumatic drug  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (EXP)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bromobenzene  (ISO)
Butylbenzyl phthalate  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
citric acid  (EXP,ISO)
Cuprizon  (ISO)
dextran sulfate  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diethylene glycol  (EXP)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
flavonoids  (ISO)
fluconazole  (ISO)
furan  (ISO)
genistein  (ISO)
GW 4064  (ISO)
hydroquinone O-beta-D-glucopyranoside  (EXP)
irinotecan  (ISO)
lithium atom  (EXP,ISO)
lithium hydride  (EXP,ISO)
mercury dichloride  (ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
methoxychlor  (ISO)
monosodium L-glutamate  (ISO)
N-(p-amylcinnamoyl)anthranilic acid  (EXP)
N-nitrosodiethylamine  (ISO)
nickel atom  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
phenformin  (ISO)
phenobarbital  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
rotenone  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
sodium fluoride  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (EXP,ISO)
vanadium atom  (EXP)
vanadium(0)  (EXP)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Additional References at PubMed
PMID:8967342   PMID:10343111   PMID:12445824   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15620109   PMID:15774465   PMID:16211368   PMID:16344560   PMID:17470169   PMID:18161988  
PMID:19056867   PMID:20424473   PMID:20610529   PMID:21257749   PMID:21873635   PMID:23376485   PMID:26167880   PMID:26176240   PMID:27639591   PMID:27927654   PMID:28514442   PMID:28731330  
PMID:30155711   PMID:31391242   PMID:32296183   PMID:32814053  


Genomics

Comparative Map Data
SLC13A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1728,473,293 - 28,497,781 (+)EnsemblGRCh38hg38GRCh38
GRCh381728,473,357 - 28,497,781 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371726,800,662 - 26,824,799 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,824,791 - 23,848,514 (+)NCBINCBI36hg18NCBI36
Build 341723,824,790 - 23,848,514NCBI
Celera1723,659,792 - 23,683,926 (+)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1723,009,855 - 23,034,040 (+)NCBIHuRef
CHM1_11726,864,116 - 26,888,251 (+)NCBICHM1_1
Slc13a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,288,102 - 78,313,107 (-)NCBIGRCm39mm39
GRCm39 Ensembl1178,287,913 - 78,313,043 (-)Ensembl
GRCm381178,397,276 - 78,422,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,397,087 - 78,422,217 (-)EnsemblGRCm38mm10GRCm38
MGSCv371178,210,778 - 78,235,687 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,213,471 - 78,238,380 (-)NCBImm8
Celera1188,029,358 - 88,054,267 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
Slc13a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21063,291,813 - 63,319,127 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1063,291,815 - 63,319,127 (-)Ensembl
Rnor_6.01065,664,665 - 65,692,046 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,664,667 - 65,692,023 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01065,951,596 - 65,979,408 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,503,787 - 64,531,097 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11064,517,411 - 64,544,720 (-)NCBI
Celera1062,268,477 - 62,295,791 (-)NCBICelera
Cytogenetic Map10q25NCBI
Slc13a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,648,703 - 4,674,466 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554814,650,356 - 4,674,441 (-)NCBIChiLan1.0ChiLan1.0
SLC13A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11728,781,200 - 28,805,268 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1728,781,200 - 28,805,268 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01728,278,381 - 28,302,318 (-)NCBIMhudiblu_PPA_v0panPan3
SLC13A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,689,296 - 42,713,209 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,688,468 - 42,712,678 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,845,952 - 41,869,885 (+)NCBI
ROS_Cfam_1.0943,508,195 - 43,532,099 (+)NCBI
UMICH_Zoey_3.1942,291,351 - 42,315,214 (+)NCBI
UNSW_CanFamBas_1.0942,583,710 - 42,607,627 (+)NCBI
UU_Cfam_GSD_1.0942,661,122 - 42,685,125 (+)NCBI
Slc13a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560241,807,531 - 41,830,571 (+)NCBI
SpeTri2.0NW_0049365384,685,538 - 4,708,049 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC13A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1244,730,773 - 44,754,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11244,733,038 - 44,754,476 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21885,939 - 110,231 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC13A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,241,878 - 22,266,959 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1622,242,514 - 22,267,036 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660757,860,797 - 7,885,832 (-)NCBIVero_WHO_p1.0
Slc13a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247861,068,013 - 1,091,868 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH71217  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,824,144 - 26,824,332UniSTSGRCh37
Build 361723,848,271 - 23,848,459RGDNCBI36
Celera1723,683,271 - 23,683,459RGD
Cytogenetic Map17p13.2UniSTS
HuRef1723,033,385 - 23,033,573UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5773
Count of miRNA genes:998
Interacting mature miRNAs:1222
Transcripts:ENST00000314669, ENST00000444914, ENST00000459818, ENST00000537681, ENST00000541739, ENST00000545060, ENST00000577903, ENST00000579281
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage pharyngeal arch
High
Medium 267 10 145 117 11 318 3 1 96 8 5 134 3 187
Low 346 5 155 169 55 148 885 9 5 121 234 73 20 32 478 2
Below cutoff 980 1220 977 260 564 255 1339 907 1991 69 763 808 9 1 513 939

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_051960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001145975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001346683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001346684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006722165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC015917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK091926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW024214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB204108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB320886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U26209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000314669   ⟹   ENSP00000316202
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1728,473,644 - 28,497,781 (+)Ensembl
RefSeq Acc Id: ENST00000444914   ⟹   ENSP00000392411
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1728,473,293 - 28,497,778 (+)Ensembl
RefSeq Acc Id: ENST00000459818   ⟹   ENSP00000464074
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1728,473,738 - 28,497,778 (+)Ensembl
RefSeq Acc Id: ENST00000541739
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1728,473,738 - 28,494,076 (+)Ensembl
RefSeq Acc Id: ENST00000545060   ⟹   ENSP00000441935
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1728,473,646 - 28,493,903 (+)Ensembl
RefSeq Acc Id: ENST00000577903   ⟹   ENSP00000463457
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1728,473,692 - 28,497,318 (+)Ensembl
RefSeq Acc Id: ENST00000579281   ⟹   ENSP00000463421
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1728,473,738 - 28,497,694 (+)Ensembl
RefSeq Acc Id: NM_001145975   ⟹   NP_001139447
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,644 - 28,497,781 (+)NCBI
GRCh371726,800,664 - 26,824,799 (+)ENTREZGENE
HuRef1723,009,855 - 23,034,040 (+)ENTREZGENE
CHM1_11726,864,116 - 26,888,251 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001346683   ⟹   NP_001333612
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,644 - 28,497,781 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001346684   ⟹   NP_001333613
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,644 - 28,497,781 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003984   ⟹   NP_003975
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,644 - 28,497,781 (+)NCBI
GRCh371726,800,664 - 26,824,799 (+)ENTREZGENE
Build 361723,824,791 - 23,848,514 (+)NCBI Archive
HuRef1723,009,855 - 23,034,040 (+)ENTREZGENE
CHM1_11726,864,116 - 26,888,251 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006722165   ⟹   XP_006722228
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,738 - 28,497,781 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011525450   ⟹   XP_011523752
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,379 - 28,497,781 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011525451   ⟹   XP_011523753
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,725 - 28,497,781 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011525452   ⟹   XP_011523754
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,646 - 28,497,781 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011525453   ⟹   XP_011523755
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,372 - 28,497,781 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011525454   ⟹   XP_011523756
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,357 - 28,494,370 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001139447   ⟸   NM_001145975
- Peptide Label: isoform a
- UniProtKB: Q13183 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_003975   ⟸   NM_003984
- Peptide Label: isoform b
- UniProtKB: Q13183 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006722228   ⟸   XM_006722165
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_011523756   ⟸   XM_011525454
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_011523755   ⟸   XM_011525453
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011523752   ⟸   XM_011525450
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011523754   ⟸   XM_011525452
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011523753   ⟸   XM_011525451
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001333613   ⟸   NM_001346684
- Peptide Label: isoform e
- Sequence:
RefSeq Acc Id: NP_001333612   ⟸   NM_001346683
- Peptide Label: isoform d
- Sequence:
RefSeq Acc Id: ENSP00000441935   ⟸   ENST00000545060
RefSeq Acc Id: ENSP00000392411   ⟸   ENST00000444914
RefSeq Acc Id: ENSP00000464074   ⟸   ENST00000459818
RefSeq Acc Id: ENSP00000463457   ⟸   ENST00000577903
RefSeq Acc Id: ENSP00000316202   ⟸   ENST00000314669
RefSeq Acc Id: ENSP00000463421   ⟸   ENST00000579281

Promoters
RGD ID:7234357
Promoter ID:EPDNEW_H22924
Type:multiple initiation site
Name:SLC13A2_1
Description:solute carrier family 13 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,473,644 - 28,473,704EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_003984.4(SLC13A2):c.1326G>A (p.Glu442=) single nucleotide variant not provided [RCV000054671] Chr17:28495672 [GRCh38]
Chr17:26822690 [GRCh37]
Chr17:17q11.2
uncertain significance
NM_003984.4(SLC13A2):c.1370C>T (p.Pro457Leu) single nucleotide variant not provided [RCV000054672] Chr17:28495716 [GRCh38]
Chr17:26822734 [GRCh37]
Chr17:17q11.2
uncertain significance
NM_001145975.1(SLC13A2):c.400G>A (p.Asp134Asn) single nucleotide variant Malignant melanoma [RCV000071377] Chr17:28490475 [GRCh38]
Chr17:26817493 [GRCh37]
Chr17:23841620 [NCBI36]
Chr17:17q11.2
not provided
GRCh38/hg38 17q11.2(chr17:28283125-28904397)x3 copy number gain See cases [RCV000136494] Chr17:28283125..28904397 [GRCh38]
Chr17:26610151..27231415 [GRCh37]
Chr17:23634278..24255541 [NCBI36]
Chr17:17q11.2
benign
GRCh37/hg19 17q11.1-11.2(chr17:25403446-31685464)x3 copy number gain not provided [RCV000762776] Chr17:25403446..31685464 [GRCh37]
Chr17:17q11.1-11.2
likely pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17q11.1-11.2(chr17:25248166-30645676)x1 copy number loss Mitogen-activated protein kinase kinase inhibitor response [RCV000626439] Chr17:25248166..30645676 [GRCh37]
Chr17:17q11.1-11.2
drug response
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p11.2-q11.2(chr17:21279289-27474974)x2 copy number gain not provided [RCV000739439] Chr17:21279289..27474974 [GRCh37]
Chr17:17p11.2-q11.2
likely pathogenic
GRCh37/hg19 17p11.2-q21.2(chr17:21690653-38772647)x3 copy number gain not provided [RCV000846852] Chr17:21690653..38772647 [GRCh37]
Chr17:17p11.2-q21.2
pathogenic
GRCh37/hg19 17q11.1-11.2(chr17:25274363-28450707)x3 copy number gain not provided [RCV001006886] Chr17:25274363..28450707 [GRCh37]
Chr17:17q11.1-11.2
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:10917 AgrOrtholog
COSMIC SLC13A2 COSMIC
Ensembl Genes ENSG00000007216 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000316202 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000392411 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000441935 UniProtKB/TrEMBL
  ENSP00000463421 UniProtKB/TrEMBL
  ENSP00000463457 UniProtKB/TrEMBL
  ENSP00000464074 UniProtKB/TrEMBL
Ensembl Transcript ENST00000314669 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000444914 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000459818 UniProtKB/TrEMBL
  ENST00000545060 UniProtKB/TrEMBL
  ENST00000577903 UniProtKB/TrEMBL
  ENST00000579281 UniProtKB/TrEMBL
GTEx ENSG00000007216 GTEx
HGNC ID HGNC:10917 ENTREZGENE
Human Proteome Map SLC13A2 Human Proteome Map
InterPro Na/sul_symport_CS UniProtKB/Swiss-Prot
  SLC13A/DASS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:9058 UniProtKB/Swiss-Prot
NCBI Gene 9058 ENTREZGENE
OMIM 604148 OMIM
Pfam Na_sulph_symp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA382 PharmGKB
PROSITE NA_SULFATE UniProtKB/Swiss-Prot
UniProt F5GWV6_HUMAN UniProtKB/TrEMBL
  J3QLA5_HUMAN UniProtKB/TrEMBL
  J3QR70_HUMAN UniProtKB/TrEMBL
  Q13183 ENTREZGENE
  Q4VAR9_HUMAN UniProtKB/TrEMBL
  Q8IV67_HUMAN UniProtKB/TrEMBL
  S13A2_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B2RBI9 UniProtKB/Swiss-Prot
  B4DPL1 UniProtKB/Swiss-Prot
  E7ETH5 UniProtKB/Swiss-Prot
  Q4VAR7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-23 SLC13A2  solute carrier family 13 member 2    solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2  Symbol and/or name change 5135510 APPROVED