CPEB1 (cytoplasmic polyadenylation element binding protein 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: CPEB1 (cytoplasmic polyadenylation element binding protein 1) Homo sapiens
Analyze
Symbol: CPEB1
Name: cytoplasmic polyadenylation element binding protein 1
RGD ID: 1321314
HGNC Page HGNC
Description: Predicted to enable mRNA 3'-UTR AU-rich region binding activity; ribosome binding activity; and translation regulator activity, nucleic acid binding. Involved in several processes, including cellular response to insulin stimulus; negative regulation of cytoplasmic translation; and positive regulation of mRNA polyadenylation. Located in cytosol and nucleoplasm. Biomarker of liver cirrhosis.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CEBP; CPE-binding protein 1; CPE-BP1; CPEB; CPEB-1; cytoplasmic polyadenylation element-binding protein 1; FLJ13203; h-CEBP; h-CPEB; hCPEB-1; LOC107987415; MGC34136; MGC60106; uncharacterized LOC107987415
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381582,543,201 - 82,648,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1582,543,201 - 82,648,861 (-)EnsemblGRCh38hg38GRCh38
GRCh371583,211,951 - 83,317,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361581,009,006 - 81,113,783 (-)NCBINCBI36hg18NCBI36
Build 341581,009,640 - 81,094,275NCBI
Celera1561,263,397 - 61,367,744 (+)NCBI
Cytogenetic Map15q25.2NCBI
HuRef1559,482,509 - 59,586,909 (-)NCBIHuRef
CHM1_11582,953,574 - 83,058,345 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:9847074   PMID:11223249   PMID:11433366   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15731006   PMID:15966895   PMID:16344560   PMID:17207965   PMID:18752464  
PMID:18923137   PMID:19141477   PMID:19161537   PMID:20062064   PMID:20144904   PMID:20339377   PMID:21244100   PMID:21478871   PMID:21832049   PMID:21873635   PMID:21988832   PMID:22052064  
PMID:22253608   PMID:22334078   PMID:22456264   PMID:22727665   PMID:23178487   PMID:23434754   PMID:23446545   PMID:23500490   PMID:23776146   PMID:23788032   PMID:23892092   PMID:24141422  
PMID:25216517   PMID:26398195   PMID:26411364   PMID:26456073   PMID:27000226   PMID:27027998   PMID:27091989   PMID:27142352   PMID:27775709   PMID:28383716   PMID:28514442   PMID:29395067  
PMID:30106109   PMID:30411210   PMID:31521690   PMID:32113875   PMID:32354341   PMID:32694731   PMID:33162033   PMID:33892791   PMID:33961781   PMID:34586830   PMID:35140242  


Genomics

Comparative Map Data
CPEB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381582,543,201 - 82,648,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1582,543,201 - 82,648,861 (-)EnsemblGRCh38hg38GRCh38
GRCh371583,211,951 - 83,317,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361581,009,006 - 81,113,783 (-)NCBINCBI36hg18NCBI36
Build 341581,009,640 - 81,094,275NCBI
Celera1561,263,397 - 61,367,744 (+)NCBI
Cytogenetic Map15q25.2NCBI
HuRef1559,482,509 - 59,586,909 (-)NCBIHuRef
CHM1_11582,953,574 - 83,058,345 (-)NCBICHM1_1
Cpeb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39780,996,774 - 81,107,749 (-)NCBIGRCm39mm39
GRCm39 Ensembl780,996,774 - 81,105,213 (-)Ensembl
GRCm38781,347,026 - 81,458,001 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl781,347,026 - 81,455,465 (-)EnsemblGRCm38mm10GRCm38
MGSCv37788,492,329 - 88,599,562 (-)NCBIGRCm37mm9NCBIm37
MGSCv36781,220,956 - 81,328,189 (-)NCBImm8
Celera778,752,617 - 78,860,054 (-)NCBICelera
Cytogenetic Map7D3NCBI
Cpeb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21135,300,048 - 135,407,688 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1135,300,461 - 135,409,760 (-)Ensembl
Rnor_6.01143,171,457 - 143,278,485 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1143,171,264 - 143,278,485 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01144,114,219 - 144,220,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,556,766 - 137,666,929 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11137,635,181 - 137,745,334 (-)NCBI
Celera1127,351,540 - 127,457,741 (-)NCBICelera
Cytogenetic Map1q31NCBI
Cpeb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541613,981,657 - 14,039,705 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541613,963,300 - 14,038,691 (+)NCBIChiLan1.0ChiLan1.0
CPEB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11580,443,096 - 80,546,163 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1580,443,096 - 80,526,948 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01562,949,264 - 63,053,994 (+)NCBIMhudiblu_PPA_v0panPan3
CPEB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1354,405,140 - 54,499,614 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl354,405,717 - 54,500,221 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha357,046,122 - 57,140,348 (-)NCBI
ROS_Cfam_1.0354,824,324 - 54,918,693 (-)NCBI
UMICH_Zoey_3.1354,344,656 - 54,439,210 (-)NCBI
UNSW_CanFamBas_1.0354,553,850 - 54,648,105 (-)NCBI
UU_Cfam_GSD_1.0354,896,337 - 54,990,718 (-)NCBI
Cpeb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640129,039,489 - 129,118,232 (+)NCBI
SpeTri2.0NW_00493648317,216,288 - 17,296,430 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPEB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl752,304,472 - 52,383,734 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1752,329,054 - 52,382,408 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2757,815,438 - 57,867,976 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CPEB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1293,005,891 - 3,106,732 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl293,006,532 - 3,106,793 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605943,983,927 - 44,084,653 (-)NCBIVero_WHO_p1.0
Cpeb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476818,386,415 - 18,468,879 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
SHGC-68593  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371583,220,962 - 83,221,192UniSTSGRCh37
Build 361581,018,017 - 81,018,247RGDNCBI36
Celera1561,358,500 - 61,358,730RGD
Cytogenetic Map15q25.2UniSTS
HuRef1559,491,520 - 59,491,750UniSTS
TNG Radiation Hybrid Map1532739.0UniSTS
SHGC-105754  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371583,226,739 - 83,227,032UniSTSGRCh37
Build 361581,023,794 - 81,024,087RGDNCBI36
Celera1561,352,660 - 61,352,953RGD
Cytogenetic Map15q25.2UniSTS
HuRef1559,497,297 - 59,497,590UniSTS
TNG Radiation Hybrid Map1532743.0UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4996
Count of miRNA genes:1078
Interacting mature miRNAs:1336
Transcripts:ENST00000261723, ENST00000398591, ENST00000398592, ENST00000423133, ENST00000450751, ENST00000562019, ENST00000563519, ENST00000563800, ENST00000564522, ENST00000566716, ENST00000567678, ENST00000568128, ENST00000568757, ENST00000568994, ENST00000569015, ENST00000569257, ENST00000570205, ENST00000570229
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 21 1 277 2 3 2 432 16 1819 8 477 12 403
Low 2090 1758 971 162 472 17 3588 1521 1863 198 822 1344 148 1166 2119
Below cutoff 195 1175 330 319 1261 303 332 648 24 154 100 197 19 38 266 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001079533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001079534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001079535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001288820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_030594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC010724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC110291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC245033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM715948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX649159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA340952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA705313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY007452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY191346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000563519
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,633,182 - 82,648,378 (-)Ensembl
RefSeq Acc Id: ENST00000566716
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,627,289 - 82,648,861 (-)Ensembl
RefSeq Acc Id: ENST00000567678   ⟹   ENSP00000457137
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,571,446 - 82,647,503 (-)Ensembl
RefSeq Acc Id: ENST00000568994   ⟹   ENSP00000455044
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,557,799 - 82,572,078 (-)Ensembl
RefSeq Acc Id: ENST00000569257   ⟹   ENSP00000455268
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,571,391 - 82,647,123 (-)Ensembl
RefSeq Acc Id: ENST00000570205
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,557,522 - 82,571,447 (-)Ensembl
RefSeq Acc Id: ENST00000611031   ⟹   ENSP00000483951
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,543,204 - 82,628,152 (-)Ensembl
RefSeq Acc Id: ENST00000611163   ⟹   ENSP00000483857
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,544,295 - 82,571,759 (-)Ensembl
RefSeq Acc Id: ENST00000614918   ⟹   ENSP00000481010
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,543,203 - 82,630,185 (-)Ensembl
RefSeq Acc Id: ENST00000614977   ⟹   ENSP00000478841
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,544,453 - 82,571,784 (-)Ensembl
RefSeq Acc Id: ENST00000615198   ⟹   ENSP00000477715
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,544,273 - 82,647,977 (-)Ensembl
RefSeq Acc Id: ENST00000616959   ⟹   ENSP00000479625
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,544,295 - 82,573,211 (-)Ensembl
RefSeq Acc Id: ENST00000617462   ⟹   ENSP00000477557
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,544,297 - 82,571,809 (-)Ensembl
RefSeq Acc Id: ENST00000617522   ⟹   ENSP00000481009
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,544,358 - 82,647,359 (-)Ensembl
RefSeq Acc Id: ENST00000617958   ⟹   ENSP00000478598
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,543,834 - 82,628,469 (-)Ensembl
RefSeq Acc Id: ENST00000618449   ⟹   ENSP00000483590
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,543,834 - 82,571,823 (-)Ensembl
RefSeq Acc Id: ENST00000618698
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,543,201 - 82,556,536 (-)Ensembl
RefSeq Acc Id: ENST00000620182   ⟹   ENSP00000484549
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,544,310 - 82,647,605 (-)Ensembl
RefSeq Acc Id: ENST00000684509   ⟹   ENSP00000507835
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1582,543,201 - 82,647,363 (-)Ensembl
RefSeq Acc Id: NM_001079533   ⟹   NP_001073001
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,571,766 (-)NCBI
GRCh371583,211,948 - 83,316,762 (-)NCBI
Build 361581,009,006 - 81,037,628 (-)NCBI Archive
HuRef1559,482,509 - 59,586,948 (-)NCBI
CHM1_11582,953,574 - 82,982,196 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001079534   ⟹   NP_001073002
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,571,766 (-)NCBI
GRCh371583,211,948 - 83,316,762 (-)NCBI
Build 361581,009,006 - 81,037,628 (-)NCBI Archive
HuRef1559,482,509 - 59,586,948 (-)NCBI
CHM1_11582,953,574 - 82,982,196 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001079535   ⟹   NP_001073003
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,571,766 (-)NCBI
GRCh371583,211,948 - 83,316,762 (-)NCBI
Build 361581,009,006 - 81,037,628 (-)NCBI Archive
HuRef1559,482,509 - 59,586,948 (-)NCBI
CHM1_11582,953,574 - 82,982,196 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001288819   ⟹   NP_001275748
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
HuRef1559,482,509 - 59,586,948 (-)NCBI
CHM1_11582,953,574 - 83,057,973 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001288820   ⟹   NP_001275749
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,571,766 (-)NCBI
HuRef1559,482,509 - 59,586,948 (-)NCBI
CHM1_11582,953,574 - 82,982,196 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365240   ⟹   NP_001352169
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,648,795 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365241   ⟹   NP_001352170
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365242   ⟹   NP_001352171
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365243   ⟹   NP_001352172
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,648,050 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365244   ⟹   NP_001352173
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365245   ⟹   NP_001352174
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,648,795 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365246   ⟹   NP_001352175
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,648,795 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365247   ⟹   NP_001352176
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,608 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365248   ⟹   NP_001352177
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,572,066 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365249   ⟹   NP_001352178
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,571,766 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365250   ⟹   NP_001352179
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,572,066 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387061   ⟹   NP_001373990
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387062   ⟹   NP_001373991
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,648,795 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387063   ⟹   NP_001373992
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387064   ⟹   NP_001373993
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387065   ⟹   NP_001373994
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,608 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387066   ⟹   NP_001373995
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387067   ⟹   NP_001373996
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387068   ⟹   NP_001373997
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387069   ⟹   NP_001373998
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,648,795 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387070   ⟹   NP_001373999
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,648,050 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387071   ⟹   NP_001374000
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387072   ⟹   NP_001374001
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387073   ⟹   NP_001374002
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387074   ⟹   NP_001374003
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387075   ⟹   NP_001374004
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387076   ⟹   NP_001374005
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,647,363 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387077   ⟹   NP_001374006
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,572,066 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387078   ⟹   NP_001374007
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,572,066 (-)NCBI
Sequence:
RefSeq Acc Id: NM_030594   ⟹   NP_085097
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,543,201 - 82,648,050 (-)NCBI
GRCh371583,211,948 - 83,316,762 (-)NCBI
Build 361581,009,006 - 81,113,783 (-)NCBI Archive
HuRef1559,482,509 - 59,586,948 (-)NCBI
CHM1_11582,953,574 - 83,058,384 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001073001 (Get FASTA)   NCBI Sequence Viewer  
  NP_001073002 (Get FASTA)   NCBI Sequence Viewer  
  NP_001073003 (Get FASTA)   NCBI Sequence Viewer  
  NP_001275748 (Get FASTA)   NCBI Sequence Viewer  
  NP_001275749 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352169 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352170 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352171 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352172 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352173 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352174 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352175 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352176 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352177 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352178 (Get FASTA)   NCBI Sequence Viewer  
  NP_001352179 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373990 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373991 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373992 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373993 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373994 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373995 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373996 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373997 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373998 (Get FASTA)   NCBI Sequence Viewer  
  NP_001373999 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374000 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374001 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374002 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374003 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374004 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374005 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374006 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374007 (Get FASTA)   NCBI Sequence Viewer  
  NP_085097 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH35348 (Get FASTA)   NCBI Sequence Viewer  
  AAH50629 (Get FASTA)   NCBI Sequence Viewer  
  AAK01239 (Get FASTA)   NCBI Sequence Viewer  
  AAK01240 (Get FASTA)   NCBI Sequence Viewer  
  BAB14496 (Get FASTA)   NCBI Sequence Viewer  
  BAG63194 (Get FASTA)   NCBI Sequence Viewer  
  BAH11723 (Get FASTA)   NCBI Sequence Viewer  
  BAH13212 (Get FASTA)   NCBI Sequence Viewer  
  EAW62448 (Get FASTA)   NCBI Sequence Viewer  
  EAW62449 (Get FASTA)   NCBI Sequence Viewer  
  EAW62450 (Get FASTA)   NCBI Sequence Viewer  
  EAW62451 (Get FASTA)   NCBI Sequence Viewer  
  EAW62452 (Get FASTA)   NCBI Sequence Viewer  
  Q9BZB8 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_085097   ⟸   NM_030594
- Peptide Label: isoform 1
- UniProtKB: Q9BZB8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001073002   ⟸   NM_001079534
- Peptide Label: isoform 3
- UniProtKB: Q9BZB8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001073001   ⟸   NM_001079533
- Peptide Label: isoform 2
- UniProtKB: Q9BZB8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001073003   ⟸   NM_001079535
- Peptide Label: isoform 3
- UniProtKB: Q9BZB8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001275748   ⟸   NM_001288819
- Peptide Label: isoform 3
- UniProtKB: Q9BZB8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001275749   ⟸   NM_001288820
- Peptide Label: isoform 4
- UniProtKB: B4DWY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001352174   ⟸   NM_001365245
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001352175   ⟸   NM_001365246
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001352169   ⟸   NM_001365240
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001352172   ⟸   NM_001365243
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001352176   ⟸   NM_001365247
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001352173   ⟸   NM_001365244
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001352170   ⟸   NM_001365241
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001352171   ⟸   NM_001365242
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001352177   ⟸   NM_001365248
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001352179   ⟸   NM_001365250
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001352178   ⟸   NM_001365249
- Peptide Label: isoform 3
RefSeq Acc Id: ENSP00000484549   ⟸   ENST00000620182
RefSeq Acc Id: ENSP00000483857   ⟸   ENST00000611163
RefSeq Acc Id: ENSP00000483951   ⟸   ENST00000611031
RefSeq Acc Id: ENSP00000478841   ⟸   ENST00000614977
RefSeq Acc Id: ENSP00000481010   ⟸   ENST00000614918
RefSeq Acc Id: ENSP00000477715   ⟸   ENST00000615198
RefSeq Acc Id: ENSP00000479625   ⟸   ENST00000616959
RefSeq Acc Id: ENSP00000481009   ⟸   ENST00000617522
RefSeq Acc Id: ENSP00000477557   ⟸   ENST00000617462
RefSeq Acc Id: ENSP00000478598   ⟸   ENST00000617958
RefSeq Acc Id: ENSP00000483590   ⟸   ENST00000618449
RefSeq Acc Id: ENSP00000457137   ⟸   ENST00000567678
RefSeq Acc Id: ENSP00000455044   ⟸   ENST00000568994
RefSeq Acc Id: ENSP00000455268   ⟸   ENST00000569257
RefSeq Acc Id: NP_001373991   ⟸   NM_001387062
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001373998   ⟸   NM_001387069
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001373999   ⟸   NM_001387070
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001373994   ⟸   NM_001387065
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001374003   ⟸   NM_001387074
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001374005   ⟸   NM_001387076
- Peptide Label: isoform 8
RefSeq Acc Id: NP_001373997   ⟸   NM_001387068
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001374004   ⟸   NM_001387075
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001374001   ⟸   NM_001387072
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001374000   ⟸   NM_001387071
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001373992   ⟸   NM_001387063
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001373996   ⟸   NM_001387067
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001374002   ⟸   NM_001387073
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001373993   ⟸   NM_001387064
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001373990   ⟸   NM_001387061
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001373995   ⟸   NM_001387066
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001374006   ⟸   NM_001387077
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001374007   ⟸   NM_001387078
- Peptide Label: isoform 4
RefSeq Acc Id: ENSP00000507835   ⟸   ENST00000684509
Protein Domains
CEBP1_N   RRM

Protein Structures
Name Modeller Protein Id AA Range Protein Structure Video
AF-Q9BZB8-F1-model_v2 AlphaFold Q9BZB8 1-566 view protein structure  

Promoters
RGD ID:6792190
Promoter ID:HG_KWN:22169
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:NM_001079533,   NM_001079534,   NM_001079535
Position:
Human AssemblyChrPosition (strand)Source
Build 361581,037,441 - 81,037,941 (-)MPROMDB
RGD ID:6792191
Promoter ID:HG_KWN:22173
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Jurkat,   K562,   Lymphoblastoid
Transcripts:ENST00000398592,   NM_030594
Position:
Human AssemblyChrPosition (strand)Source
Build 361581,113,341 - 81,113,841 (-)MPROMDB
RGD ID:7230327
Promoter ID:EPDNEW_H20909
Type:multiple initiation site
Name:CPEB1_4
Description:cytoplasmic polyadenylation element binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H20910  EPDNEW_H20911  EPDNEW_H20912  EPDNEW_H20913  EPDNEW_H20914  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,544,300 - 82,544,360EPDNEW
RGD ID:7230329
Promoter ID:EPDNEW_H20910
Type:initiation region
Name:CPEB1_5
Description:cytoplasmic polyadenylation element binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H20909  EPDNEW_H20911  EPDNEW_H20912  EPDNEW_H20913  EPDNEW_H20914  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,544,503 - 82,544,563EPDNEW
RGD ID:7230331
Promoter ID:EPDNEW_H20911
Type:multiple initiation site
Name:CPEB1_6
Description:cytoplasmic polyadenylation element binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H20909  EPDNEW_H20910  EPDNEW_H20912  EPDNEW_H20913  EPDNEW_H20914  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,556,024 - 82,556,084EPDNEW
RGD ID:7230333
Promoter ID:EPDNEW_H20912
Type:initiation region
Name:CPEB1_1
Description:cytoplasmic polyadenylation element binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H20909  EPDNEW_H20910  EPDNEW_H20911  EPDNEW_H20913  EPDNEW_H20914  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,571,766 - 82,571,826EPDNEW
RGD ID:7230335
Promoter ID:EPDNEW_H20913
Type:initiation region
Name:CPEB1_3
Description:cytoplasmic polyadenylation element binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H20909  EPDNEW_H20910  EPDNEW_H20911  EPDNEW_H20912  EPDNEW_H20914  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,572,066 - 82,572,126EPDNEW
RGD ID:7230337
Promoter ID:EPDNEW_H20914
Type:initiation region
Name:CPEB1_2
Description:cytoplasmic polyadenylation element binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H20909  EPDNEW_H20910  EPDNEW_H20911  EPDNEW_H20912  EPDNEW_H20913  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381582,647,947 - 82,648,007EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 15q25.2(chr15:82558402-84121082)x3 copy number gain See cases [RCV000051826] Chr15:82558402..84121082 [GRCh38]
Chr15:83214012..84789834 [GRCh37]
Chr15:81011067..82580838 [NCBI36]
Chr15:15q25.2
pathogenic
GRCh38/hg38 15q24.2-26.3(chr15:75307767-101723215)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052346]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052346]|See cases [RCV000052346] Chr15:75307767..101723215 [GRCh38]
Chr15:75600108..102263418 [GRCh37]
Chr15:73387161..100080941 [NCBI36]
Chr15:15q24.2-26.3
pathogenic
GRCh38/hg38 15q24.3-26.3(chr15:77543797-101843411)x3 copy number gain See cases [RCV000052347] Chr15:77543797..101843411 [GRCh38]
Chr15:77836139..102383614 [GRCh37]
Chr15:75623194..100201137 [NCBI36]
Chr15:15q24.3-26.3
pathogenic
GRCh38/hg38 15q25.2-25.3(chr15:82627214-85243616)x1 copy number loss See cases [RCV000143125] Chr15:82627214..85243616 [GRCh38]
Chr15:83083418..85786847 [GRCh37]
Chr15:80880473..83587851 [NCBI36]
Chr15:15q25.2-25.3
likely pathogenic
GRCh38/hg38 15q25.2-25.3(chr15:82560915-85185613)x1 copy number loss See cases [RCV000137052] Chr15:82560915..85185613 [GRCh38]
Chr15:83229665..85728844 [GRCh37]
Chr15:81026720..83529848 [NCBI36]
Chr15:15q25.2-25.3
likely pathogenic|uncertain significance
GRCh38/hg38 15q23-26.3(chr15:72154949-101920998)x3 copy number gain See cases [RCV000143019] Chr15:72154949..101920998 [GRCh38]
Chr15:72447290..102461201 [GRCh37]
Chr15:70234344..100278724 [NCBI36]
Chr15:15q23-26.3
pathogenic
GRCh38/hg38 15q22.2-26.3(chr15:59828460-101920998)x3 copy number gain See cases [RCV000142915] Chr15:59828460..101920998 [GRCh38]
Chr15:60120659..102461201 [GRCh37]
Chr15:57907951..100278724 [NCBI36]
Chr15:15q22.2-26.3
pathogenic
GRCh37/hg19 15q25.2(chr15:83213963-84811815)x1 copy number loss Premature ovarian failure [RCV000225327] Chr15:83213963..84811815 [GRCh37]
Chr15:15q25.2
likely pathogenic
GRCh37/hg19 15q24.2-26.3(chr15:76061144-102429112)x3 copy number gain See cases [RCV000511332] Chr15:76061144..102429112 [GRCh37]
Chr15:15q24.2-26.3
pathogenic
GRCh37/hg19 15q25.2(chr15:82133231-83455333)x3 copy number gain See cases [RCV000240449] Chr15:82133231..83455333 [GRCh37]
Chr15:15q25.2
uncertain significance
GRCh37/hg19 15q22.31-26.3(chr15:64637227-102509910)x3 copy number gain See cases [RCV000240602] Chr15:64637227..102509910 [GRCh37]
Chr15:15q22.31-26.3
pathogenic
GRCh37/hg19 15q22.1-26.3(chr15:59297293-102480888)x3 copy number gain not provided [RCV000415836] Chr15:59297293..102480888 [GRCh37]
Chr15:15q22.1-26.3
likely pathogenic
GRCh37/hg19 15q25.1-25.2(chr15:80703867-83955596)x1 copy number loss See cases [RCV000446990] Chr15:80703867..83955596 [GRCh37]
Chr15:15q25.1-25.2
pathogenic
GRCh37/hg19 15q15.1-26.3(chr15:41745084-102354798)x4 copy number gain See cases [RCV000447123] Chr15:41745084..102354798 [GRCh37]
Chr15:15q15.1-26.3
pathogenic
GRCh37/hg19 15q25.1-26.3(chr15:80648093-102429112)x3 copy number gain See cases [RCV000445705] Chr15:80648093..102429112 [GRCh37]
Chr15:15q25.1-26.3
pathogenic
GRCh37/hg19 15q11.2-26.3(chr15:20733395-102511616)x4 copy number gain See cases [RCV000447765] Chr15:20733395..102511616 [GRCh37]
Chr15:15q11.2-26.3
pathogenic
GRCh37/hg19 15q25.2(chr15:83169558-84847653)x1 copy number loss See cases [RCV000510435] Chr15:83169558..84847653 [GRCh37]
Chr15:15q25.2
likely pathogenic
GRCh37/hg19 15q11.2-26.3(chr15:22770422-102429112)x3 copy number gain See cases [RCV000510717] Chr15:22770422..102429112 [GRCh37]
Chr15:15q11.2-26.3
pathogenic
GRCh37/hg19 15q11.2-26.3(chr15:22770422-102429112) copy number gain See cases [RCV000512019] Chr15:22770422..102429112 [GRCh37]
Chr15:15q11.2-26.3
pathogenic
GRCh37/hg19 15q25.2(chr15:82606408-84970771)x3 copy number gain See cases [RCV000512491] Chr15:82606408..84970771 [GRCh37]
Chr15:15q25.2
uncertain significance
Single allele duplication not provided [RCV000677926] Chr15:31115047..102354857 [GRCh37]
Chr15:15q13.2-26.3
pathogenic
GRCh37/hg19 15q23-26.3(chr15:71329220-102270758)x3 copy number gain not provided [RCV000683703] Chr15:71329220..102270758 [GRCh37]
Chr15:15q23-26.3
pathogenic
GRCh37/hg19 15q25.1-25.3(chr15:79023343-87158823)x1,2 copy number gain not provided [RCV000683712] Chr15:79023343..87158823 [GRCh37]
Chr15:15q25.1-25.3
pathogenic
GRCh37/hg19 15q24.3-26.3(chr15:77479244-102429112)x3 copy number gain not provided [RCV000683710] Chr15:77479244..102429112 [GRCh37]
Chr15:15q24.3-26.3
pathogenic
NC_000015.9:g.83214012_84812693del1598682 deletion Primary amenorrhea [RCV000754462] Chr15:83214012..84812693 [GRCh37]
Chr15:15q25.2
likely pathogenic
NM_001365242.1(CPEB1):c.-98+1610_-98+5362del deletion Primary amenorrhea [RCV000754463] Chr15:82641775..82645527 [GRCh38]
Chr15:83310526..83314278 [GRCh37]
Chr15:15q25.2
uncertain significance
GRCh37/hg19 15q25.2(chr15:83245384-83482318)x3 copy number gain not provided [RCV000751371] Chr15:83245384..83482318 [GRCh37]
Chr15:15q25.2
benign
GRCh37/hg19 15q11.1-26.3(chr15:20016811-102493540)x3 copy number gain not provided [RCV000751155] Chr15:20016811..102493540 [GRCh37]
Chr15:15q11.1-26.3
pathogenic
GRCh37/hg19 15q11.1-26.3(chr15:20071673-102461162)x3 copy number gain not provided [RCV000751156] Chr15:20071673..102461162 [GRCh37]
Chr15:15q11.1-26.3
pathogenic
NM_001365242.1(CPEB1):c.864A>G (p.Pro288=) single nucleotide variant not provided [RCV000948209] Chr15:82555946 [GRCh38]
Chr15:83224696 [GRCh37]
Chr15:15q25.2
benign
GRCh37/hg19 15q25.2(chr15:83214012-84772030)x1 copy number loss not provided [RCV000856636] Chr15:83214012..84772030 [GRCh37]
Chr15:15q25.2
pathogenic
GRCh37/hg19 15q25.2(chr15:82688216-84796779)x1 copy number loss not provided [RCV000848551] Chr15:82688216..84796779 [GRCh37]
Chr15:15q25.2
pathogenic
GRCh37/hg19 15q25.2(chr15:82468371-84797068)x3 copy number gain not provided [RCV000846337] Chr15:82468371..84797068 [GRCh37]
Chr15:15q25.2
uncertain significance
GRCh37/hg19 15q25.1-25.2(chr15:80728654-84107646)x1 copy number loss not provided [RCV000849378] Chr15:80728654..84107646 [GRCh37]
Chr15:15q25.1-25.2
pathogenic
GRCh37/hg19 15q25.2-25.3(chr15:83201955-85786847)x1 copy number loss not provided [RCV001259716] Chr15:83201955..85786847 [GRCh37]
Chr15:15q25.2-25.3
pathogenic
NC_000015.9:g.(?_32964879)_(91358519_?)dup duplication Bloom syndrome [RCV001343104]|Familial colorectal cancer [RCV001325176] Chr15:32964879..91358519 [GRCh37]
Chr15:15q13.3-26.1
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:21744 AgrOrtholog
COSMIC CPEB1 COSMIC
Ensembl Genes ENSG00000214575 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000277445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000455044 UniProtKB/TrEMBL
  ENSP00000455268 UniProtKB/TrEMBL
  ENSP00000457137 UniProtKB/TrEMBL
  ENSP00000477557 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000477715 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000478378 UniProtKB/TrEMBL
  ENSP00000478558 UniProtKB/Swiss-Prot
  ENSP00000478598 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000478841 UniProtKB/TrEMBL
  ENSP00000479625 UniProtKB/TrEMBL
  ENSP00000481009 UniProtKB/Swiss-Prot
  ENSP00000481010 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000482116 UniProtKB/Swiss-Prot
  ENSP00000482965 UniProtKB/Swiss-Prot
  ENSP00000483590 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000483857 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000483951 UniProtKB/TrEMBL
  ENSP00000484549 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000487757 UniProtKB/Swiss-Prot
  ENSP00000487897 UniProtKB/TrEMBL
  ENSP00000488102 UniProtKB/TrEMBL
  ENSP00000488206 UniProtKB/TrEMBL
  ENSP00000488352 UniProtKB/Swiss-Prot
  ENSP00000488484 UniProtKB/TrEMBL
  ENSP00000488508 UniProtKB/TrEMBL
  ENSP00000488628 UniProtKB/TrEMBL
  ENSP00000488842 UniProtKB/TrEMBL
  ENSP00000507835 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENST00000567678 UniProtKB/TrEMBL
  ENST00000568994 UniProtKB/TrEMBL
  ENST00000569257 UniProtKB/TrEMBL
  ENST00000610719 UniProtKB/TrEMBL
  ENST00000611031 UniProtKB/TrEMBL
  ENST00000611163 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000614918 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000614977 UniProtKB/TrEMBL
  ENST00000615198 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000616775 UniProtKB/Swiss-Prot
  ENST00000616959 UniProtKB/TrEMBL
  ENST00000617462 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000617522 UniProtKB/Swiss-Prot
  ENST00000617958 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000618449 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000619696 UniProtKB/Swiss-Prot
  ENST00000620182 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000620212 UniProtKB/Swiss-Prot
  ENST00000631406 UniProtKB/TrEMBL
  ENST00000631674 UniProtKB/Swiss-Prot
  ENST00000632172 UniProtKB/TrEMBL
  ENST00000632305 UniProtKB/TrEMBL
  ENST00000632526 UniProtKB/Swiss-Prot
  ENST00000632883 UniProtKB/TrEMBL
  ENST00000633271 UniProtKB/TrEMBL
  ENST00000633293 UniProtKB/TrEMBL
  ENST00000634018 UniProtKB/TrEMBL
  ENST00000684509 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.640.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000214575 GTEx
  ENSG00000277445 GTEx
HGNC ID HGNC:21744 ENTREZGENE
Human Proteome Map CPEB1 Human Proteome Map
InterPro CEBP1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CEBP_ZZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CEBP_ZZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CPEB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CPEB1_RRM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:64506 UniProtKB/Swiss-Prot
NCBI Gene 64506 ENTREZGENE
OMIM 607342 OMIM
PANTHER PTHR12566 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CEBP1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CEBP_ZZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134929879 PharmGKB
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024R214_HUMAN UniProtKB/TrEMBL
  A0A087WUQ9_HUMAN UniProtKB/TrEMBL
  A0A087WVR7_HUMAN UniProtKB/TrEMBL
  A0A087WXG7_HUMAN UniProtKB/TrEMBL
  A0A087X171_HUMAN UniProtKB/TrEMBL
  A0A0J9YX15_HUMAN UniProtKB/TrEMBL
  A0A0J9YXP0_HUMAN UniProtKB/TrEMBL
  B4DWY2 ENTREZGENE, UniProtKB/TrEMBL
  CPEB1_HUMAN UniProtKB/Swiss-Prot
  H3BNX1_HUMAN UniProtKB/TrEMBL
  H3BPD6_HUMAN UniProtKB/TrEMBL
  H3BTE4_HUMAN UniProtKB/TrEMBL
  Q9BZB8 ENTREZGENE
UniProt Secondary B7Z6C6 UniProtKB/Swiss-Prot
  Q86W46 UniProtKB/Swiss-Prot
  Q8IV41 UniProtKB/Swiss-Prot
  Q9BZB7 UniProtKB/Swiss-Prot
  Q9H8V5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-11-26 CPEB1  cytoplasmic polyadenylation element binding protein 1  LOC107987415  uncharacterized LOC107987415  Data Merged 737654 PROVISIONAL