VSIG10L (V-set and immunoglobulin domain containing 10 like) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: VSIG10L (V-set and immunoglobulin domain containing 10 like) Homo sapiens
Analyze
Symbol: VSIG10L
Name: V-set and immunoglobulin domain containing 10 like
RGD ID: 3440350
HGNC Page HGNC:27111
Description: Located in nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: V-set and immunoglobulin domain-containing protein 10-like
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381951,331,541 - 51,342,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1951,331,536 - 51,342,139 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,834,795 - 51,845,393 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,526,607 - 56,537,190 (-)NCBINCBI36Build 36hg18NCBI36
Celera1948,886,398 - 48,896,982 (-)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1948,166,905 - 48,177,348 (-)NCBIHuRef
CHM1_11951,836,684 - 51,847,272 (-)NCBICHM1_1
T2T-CHM13v2.01954,419,802 - 54,431,866 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
nucleoplasm  (IDA)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
Additional References at PubMed
PMID:12477932   PMID:25468996   PMID:27467440   PMID:32694731  


Genomics

Comparative Map Data
VSIG10L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381951,331,541 - 51,342,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1951,331,536 - 51,342,139 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,834,795 - 51,845,393 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,526,607 - 56,537,190 (-)NCBINCBI36Build 36hg18NCBI36
Celera1948,886,398 - 48,896,982 (-)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1948,166,905 - 48,177,348 (-)NCBIHuRef
CHM1_11951,836,684 - 51,847,272 (-)NCBICHM1_1
T2T-CHM13v2.01954,419,802 - 54,431,866 (-)NCBIT2T-CHM13v2.0
Vsig10l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39743,112,460 - 43,121,443 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl743,112,575 - 43,121,443 (+)EnsemblGRCm39 Ensembl
GRCm38743,462,845 - 43,472,019 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl743,463,151 - 43,472,019 (+)EnsemblGRCm38mm10GRCm38
MGSCv37750,718,521 - 50,727,386 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36743,331,153 - 43,339,337 (+)NCBIMGSCv36mm8
Celera738,931,651 - 38,940,444 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.25NCBI
Vsig10l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81103,007,933 - 103,016,161 (+)NCBIGRCr8
mRatBN7.2193,871,487 - 93,880,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl193,851,774 - 93,879,566 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0198,458,691 - 98,467,444 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl198,459,834 - 98,467,262 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,535,492 - 99,544,225 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4193,839,802 - 93,848,377 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera188,148,540 - 88,157,297 (+)NCBICelera
Cytogenetic Map1q22NCBI
Vsig10l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555581,049,594 - 1,057,701 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555581,049,394 - 1,058,632 (+)NCBIChiLan1.0ChiLan1.0
VSIG10L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22057,369,731 - 57,380,398 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11959,291,438 - 59,301,833 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01948,267,467 - 48,278,591 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11957,153,557 - 57,165,204 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1957,154,627 - 57,163,742 (-)Ensemblpanpan1.1panPan2
VSIG10L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,629,289 - 105,638,905 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1105,630,790 - 105,638,922 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,200,837 - 105,211,625 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,137,683 - 106,148,471 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,140,357 - 106,147,234 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11105,809,557 - 105,820,344 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,450,159 - 105,460,947 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,245,712 - 106,256,507 (+)NCBIUU_Cfam_GSD_1.0
Vsig10l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934923,043,020 - 23,051,652 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493737815,352 - 23,321 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VSIG10L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl658,520,018 - 58,531,223 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1658,519,500 - 58,532,363 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,657,239 - 51,669,539 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VSIG10L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1644,255,641 - 44,266,916 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl644,256,435 - 44,265,901 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607324,302,363 - 24,315,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vsig10l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,522,041 - 3,528,963 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248323,521,926 - 3,530,040 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in VSIG10L
48 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3 copy number gain See cases [RCV000050883] Chr19:50191219..58535818 [GRCh38]
Chr19:50694476..59047185 [GRCh37]
Chr19:55386288..63738997 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3 copy number gain See cases [RCV000052926] Chr19:51141518..58539965 [GRCh38]
Chr19:51644775..59051332 [GRCh37]
Chr19:56336587..63743144 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3 copy number gain See cases [RCV000135843] Chr19:50152520..58581203 [GRCh38]
Chr19:50655777..59092570 [GRCh37]
Chr19:55347589..63784382 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41(chr19:51202361-51993020)x3 copy number gain See cases [RCV000143450] Chr19:51202361..51993020 [GRCh38]
Chr19:51705617..52496273 [GRCh37]
Chr19:56397429..57188085 [NCBI36]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19q13.41(chr19:51840736-51870742)x3 copy number gain See cases [RCV000447286] Chr19:51840736..51870742 [GRCh37]
Chr19:19q13.41		 likely benign
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3 copy number gain See cases [RCV000445925] Chr19:50489390..59095359 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.41(chr19:51840736-51853666)x3 copy number gain See cases [RCV000448571] Chr19:51840736..51853666 [GRCh37]
Chr19:19q13.41		 likely benign
NM_001163922.3(VSIG10L):c.494C>T (p.Pro165Leu) single nucleotide variant Inborn genetic diseases [RCV003297212] Chr19:51341554 [GRCh38]
Chr19:51844808 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3 copy number gain not provided [RCV000740208] Chr19:50740074..59097160 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NM_001163922.3(VSIG10L):c.1755T>G (p.His585Gln) single nucleotide variant Inborn genetic diseases [RCV003245586] Chr19:51338183 [GRCh38]
Chr19:51841437 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1880G>A (p.Arg627His) single nucleotide variant not provided [RCV000947998] Chr19:51338058 [GRCh38]
Chr19:51841312 [GRCh37]
Chr19:19q13.41		 benign
NM_001163922.3(VSIG10L):c.2306-7C>T single nucleotide variant not provided [RCV000970909] Chr19:51334311 [GRCh38]
Chr19:51837565 [GRCh37]
Chr19:19q13.41		 benign
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3 copy number gain not provided [RCV001007050] Chr19:44738088..53621561 [GRCh37]
Chr19:19q13.31-13.42		 pathogenic
NM_001163922.3(VSIG10L):c.1147C>T (p.Pro383Ser) single nucleotide variant Inborn genetic diseases [RCV003289876] Chr19:51340475 [GRCh38]
Chr19:51843729 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1088T>G (p.Leu363Arg) single nucleotide variant Inborn genetic diseases [RCV003251368] Chr19:51340534 [GRCh38]
Chr19:51843788 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.503T>G (p.Met168Arg) single nucleotide variant Inborn genetic diseases [RCV003293000] Chr19:51341545 [GRCh38]
Chr19:51844799 [GRCh37]
Chr19:19q13.41		 uncertain significance
NC_000019.9:g.(?_51727962)_(51890697_?)del deletion Multiple acyl-CoA dehydrogenase deficiency [RCV003107570] Chr19:51727962..51890697 [GRCh37]
Chr19:19q13.41		 pathogenic
NM_001163922.3(VSIG10L):c.1189+10G>A single nucleotide variant not provided [RCV000955574] Chr19:51340423 [GRCh38]
Chr19:51843677 [GRCh37]
Chr19:19q13.41		 benign
NM_001163922.3(VSIG10L):c.232T>A (p.Ser78Thr) single nucleotide variant not provided [RCV000972137] Chr19:51341816 [GRCh38]
Chr19:51845070 [GRCh37]
Chr19:19q13.41		 benign
NM_001163922.3(VSIG10L):c.2475C>T (p.Pro825=) single nucleotide variant not provided [RCV000911371] Chr19:51333890 [GRCh38]
Chr19:51837144 [GRCh37]
Chr19:19q13.41		 likely benign
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871) copy number gain not provided [RCV001249294] Chr19:47939842..54626871 [GRCh37]
Chr19:19q13.32-13.42		 not provided
GRCh37/hg19 19q13.33-13.41(chr19:50469730-51916485)x3 copy number gain not provided [RCV001007055] Chr19:50469730..51916485 [GRCh37]
Chr19:19q13.33-13.41		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438) copy number gain not specified [RCV002052689] Chr19:49911081..53127438 [GRCh37]
Chr19:19q13.33-13.41		 likely pathogenic
GRCh37/hg19 19q13.41(chr19:51769834-52415762)x3 copy number gain not provided [RCV001827892] Chr19:51769834..52415762 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1850G>C (p.Gly617Ala) single nucleotide variant Inborn genetic diseases [RCV002840362] Chr19:51338088 [GRCh38]
Chr19:51841342 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1258G>A (p.Ala420Thr) single nucleotide variant Inborn genetic diseases [RCV002901949] Chr19:51340231 [GRCh38]
Chr19:51843485 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.2243G>A (p.Arg748Gln) single nucleotide variant Inborn genetic diseases [RCV002778623] Chr19:51337300 [GRCh38]
Chr19:51840554 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1903C>T (p.Arg635Trp) single nucleotide variant Inborn genetic diseases [RCV002997394]|not provided [RCV003427659] Chr19:51338035 [GRCh38]
Chr19:51841289 [GRCh37]
Chr19:19q13.41		 likely benign|uncertain significance
NM_001163922.3(VSIG10L):c.1793T>C (p.Val598Ala) single nucleotide variant Inborn genetic diseases [RCV002688900] Chr19:51338145 [GRCh38]
Chr19:51841399 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1139T>G (p.Val380Gly) single nucleotide variant Inborn genetic diseases [RCV002980984] Chr19:51340483 [GRCh38]
Chr19:51843737 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1274C>T (p.Thr425Ile) single nucleotide variant Inborn genetic diseases [RCV002998322] Chr19:51340215 [GRCh38]
Chr19:51843469 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.317C>T (p.Pro106Leu) single nucleotide variant Inborn genetic diseases [RCV002980324] Chr19:51341731 [GRCh38]
Chr19:51844985 [GRCh37]
Chr19:19q13.41		 likely benign
NM_001163922.3(VSIG10L):c.1657C>T (p.Arg553Trp) single nucleotide variant Inborn genetic diseases [RCV002799539] Chr19:51338960 [GRCh38]
Chr19:51842214 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.2264G>A (p.Gly755Asp) single nucleotide variant Inborn genetic diseases [RCV002707139] Chr19:51337279 [GRCh38]
Chr19:51840533 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.887G>T (p.Gly296Val) single nucleotide variant Inborn genetic diseases [RCV002875500] Chr19:51341161 [GRCh38]
Chr19:51844415 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1514G>T (p.Gly505Val) single nucleotide variant Inborn genetic diseases [RCV002664981] Chr19:51339103 [GRCh38]
Chr19:51842357 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.2299C>T (p.Arg767Trp) single nucleotide variant Inborn genetic diseases [RCV002983329] Chr19:51337244 [GRCh38]
Chr19:51840498 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.497A>T (p.Asp166Val) single nucleotide variant Inborn genetic diseases [RCV002665092] Chr19:51341551 [GRCh38]
Chr19:51844805 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.614C>T (p.Thr205Ile) single nucleotide variant Inborn genetic diseases [RCV002718981] Chr19:51341434 [GRCh38]
Chr19:51844688 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.947G>T (p.Gly316Val) single nucleotide variant Inborn genetic diseases [RCV002769304] Chr19:51340675 [GRCh38]
Chr19:51843929 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1345G>C (p.Ala449Pro) single nucleotide variant Inborn genetic diseases [RCV002792500] Chr19:51340144 [GRCh38]
Chr19:51843398 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.2036A>G (p.Gln679Arg) single nucleotide variant Inborn genetic diseases [RCV002719173] Chr19:51337507 [GRCh38]
Chr19:51840761 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1190A>G (p.Tyr397Cys) single nucleotide variant Inborn genetic diseases [RCV002940002] Chr19:51340299 [GRCh38]
Chr19:51843553 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1733C>A (p.Ala578Asp) single nucleotide variant Inborn genetic diseases [RCV002703382] Chr19:51338205 [GRCh38]
Chr19:51841459 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.6C>A (p.Asp2Glu) single nucleotide variant Inborn genetic diseases [RCV002964082] Chr19:51342119 [GRCh38]
Chr19:51845373 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.394C>T (p.Pro132Ser) single nucleotide variant Inborn genetic diseases [RCV002959395] Chr19:51341654 [GRCh38]
Chr19:51844908 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1283G>A (p.Cys428Tyr) single nucleotide variant Inborn genetic diseases [RCV002748358] Chr19:51340206 [GRCh38]
Chr19:51843460 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1595C>T (p.Pro532Leu) single nucleotide variant Inborn genetic diseases [RCV002812505] Chr19:51339022 [GRCh38]
Chr19:51842276 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1216G>C (p.Val406Leu) single nucleotide variant Inborn genetic diseases [RCV002965074] Chr19:51340273 [GRCh38]
Chr19:51843527 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.404C>G (p.Ser135Cys) single nucleotide variant Inborn genetic diseases [RCV002940433] Chr19:51341644 [GRCh38]
Chr19:51844898 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.980G>C (p.Trp327Ser) single nucleotide variant Inborn genetic diseases [RCV003178988] Chr19:51340642 [GRCh38]
Chr19:51843896 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1490C>T (p.Ala497Val) single nucleotide variant Inborn genetic diseases [RCV003204536] Chr19:51339127 [GRCh38]
Chr19:51842381 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1589G>T (p.Gly530Val) single nucleotide variant Inborn genetic diseases [RCV003212287] Chr19:51339028 [GRCh38]
Chr19:51842282 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1083C>A (p.Asp361Glu) single nucleotide variant Inborn genetic diseases [RCV003203414] Chr19:51340539 [GRCh38]
Chr19:51843793 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.410C>A (p.Thr137Asn) single nucleotide variant Inborn genetic diseases [RCV003217547] Chr19:51341638 [GRCh38]
Chr19:51844892 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.85C>G (p.Gln29Glu) single nucleotide variant Inborn genetic diseases [RCV003199661] Chr19:51341963 [GRCh38]
Chr19:51845217 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.2272G>A (p.Gly758Arg) single nucleotide variant Inborn genetic diseases [RCV003183911] Chr19:51337271 [GRCh38]
Chr19:51840525 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1929C>G (p.Ser643Arg) single nucleotide variant Inborn genetic diseases [RCV003303771] Chr19:51338009 [GRCh38]
Chr19:51841263 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.137A>T (p.Gln46Leu) single nucleotide variant Inborn genetic diseases [RCV003356722] Chr19:51341911 [GRCh38]
Chr19:51845165 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.1579C>G (p.Gln527Glu) single nucleotide variant Inborn genetic diseases [RCV003383769] Chr19:51339038 [GRCh38]
Chr19:51842292 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001163922.3(VSIG10L):c.481T>G (p.Ser161Ala) single nucleotide variant Inborn genetic diseases [RCV003378344] Chr19:51341567 [GRCh38]
Chr19:51844821 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43		 likely pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1352
Count of miRNA genes:618
Interacting mature miRNAs:716
Transcripts:ENST00000335624, ENST00000600663
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-57988  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371951,834,909 - 51,835,113UniSTSGRCh37
Build 361956,526,721 - 56,526,925RGDNCBI36
Celera1948,886,512 - 48,886,716RGD
Cytogenetic Map19q13.41UniSTS
HuRef1948,167,019 - 48,167,223UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 69 12 38 142 18 36 1463 53 25 15 290 44 105 7 694 1
Low 2333 2414 1654 471 1610 417 2429 1388 3595 386 1148 1513 67 1197 1634 3 1
Below cutoff 30 556 31 11 309 11 463 750 89 17 16 31 1 1 460 3

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000335624   ⟹   ENSP00000335623
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1951,331,541 - 51,342,139 (-)Ensembl
RefSeq Acc Id: ENST00000600663
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1951,331,536 - 51,339,755 (-)Ensembl
RefSeq Acc Id: NM_001163922   ⟹   NP_001157394
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381951,331,541 - 51,342,139 (-)NCBI
GRCh371951,834,795 - 51,845,378 (-)RGD
Celera1948,886,398 - 48,896,982 (-)RGD
HuRef1948,166,905 - 48,177,348 (-)ENTREZGENE
CHM1_11951,836,684 - 51,847,272 (-)NCBI
T2T-CHM13v2.01954,419,823 - 54,430,422 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054319847   ⟹   XP_054175822
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01954,419,802 - 54,431,866 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001157394 (Get FASTA)   NCBI Sequence Viewer  
  XP_054175822 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH49212 (Get FASTA)   NCBI Sequence Viewer  
  AAI31494 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000335623
  ENSP00000335623.3
GenBank Protein Q86VR7 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001157394   ⟸   NM_001163922
- Peptide Label: precursor
- UniProtKB: Q86VR7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000335623   ⟸   ENST00000335624
RefSeq Acc Id: XP_054175822   ⟸   XM_054319847
- Peptide Label: isoform X1
Protein Domains
Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q86VR7-F1-model_v2 AlphaFold Q86VR7 1-867 view protein structure

Promoters
RGD ID:13205351
Promoter ID:EPDNEW_H26256
Type:initiation region
Name:VSIG10L_1
Description:V-set and immunoglobulin domain containing 10 like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381951,339,778 - 51,339,838EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:27111 AgrOrtholog
COSMIC VSIG10L COSMIC
Ensembl Genes ENSG00000186806 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000335624 ENTREZGENE
  ENST00000335624.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000186806 GTEx
HGNC ID HGNC:27111 ENTREZGENE
Human Proteome Map VSIG10L Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
KEGG Report hsa:147645 UniProtKB/Swiss-Prot
NCBI Gene 147645 ENTREZGENE
OMIM 617740 OMIM
PANTHER CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 UniProtKB/Swiss-Prot
  V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 10-LIKE UniProtKB/Swiss-Prot
Pfam I-set UniProtKB/Swiss-Prot
  Ig_2 UniProtKB/Swiss-Prot
PharmGKB PA165394673 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt Q86VR7 ENTREZGENE, UniProtKB/Swiss-Prot