Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PRODH (proline dehydrogenase 1) Homo sapiens
Symbol: PRODH
Name: proline dehydrogenase 1
Description: Exhibits FAD binding activity and proline dehydrogenase activity. Involved in positive regulation of cell death. Predicted to localize to mitochondrion. Implicated in amino acid metabolic disorder; hyperprolinemia type 1; and schizophrenia 4.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ33744; HSPOX2; MGC148078; MGC148079; p53-induced gene 6 protein; PIG6; POX; PRODH1; PRODH2; proline dehydrogenase (oxidase) 1; proline dehydrogenase 1, mitochondrial; proline dehydrogenase, mitochondrial; proline oxidase 2; proline oxidase, mitochondrial; schizophrenia disorder 4; SCZD4; TP53I6; tumor protein p53 inducible protein 6
Mus musculus (house mouse) : Prodh (proline dehydrogenase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prodh1 (proline dehydrogenase 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100987322 (proline dehydrogenase 1, mitochondrial)
Canis lupus familiaris (dog) : LOC477562 (proline dehydrogenase 1, mitochondrial)
Sus scrofa (pig) : LOC110256626 (proline dehydrogenase 1, mitochondrial)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2218,912,777 - 18,936,553 (-)EnsemblGRCh38hg38GRCh38
GRCh382218,912,781 - 18,936,553 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372218,900,206 - 18,924,066 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,280,295 - 17,304,066 (-)NCBINCBI36hg18NCBI36
Build 342217,274,848 - 17,298,620NCBI
Celera222,752,487 - 2,775,952 (-)NCBI
Cytogenetic Map22q11.21NCBI
HuRef222,522,549 - 2,546,463 (-)NCBIHuRef
CHM1_12218,900,046 - 18,923,816 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PRODH
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343717
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.