ESM1 Human (1->4)-beta-D-glucan multiple interactions ISO RGD:737595 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ESM1 mRNA CTD PMID:36331819 ESM1 Human (S)-colchicine decreases expression ISO RGD:71013 6480464 Colchicine results in decreased expression of ESM1 mRNA CTD PMID:20624997 ESM1 Human 1,2-dimethylhydrazine increases expression ISO RGD:737595 6480464 1,2-Dimethylhydrazine results in increased expression of ESM1 mRNA CTD PMID:22206623 ESM1 Human 1-nitropyrene increases expression EXP 6480464 1-nitropyrene results in increased expression of ESM1 mRNA CTD PMID:19041380 ESM1 Human 17beta-estradiol multiple interactions ISO RGD:737595 6480464 Estradiol promotes the reaction [Lipopolysaccharides results in increased expression of ESM1 mRNA] CTD PMID:16977382 ESM1 Human 17beta-estradiol increases expression ISO RGD:71013 6480464 Estradiol results in increased expression of ESM1 mRNA CTD PMID:35192832 ESM1 Human 17beta-estradiol affects expression ISO RGD:71013 6480464 Estradiol affects the expression of ESM1 mRNA CTD PMID:32145629 ESM1 Human 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of ESM1 mRNA CTD PMID:30165855 ESM1 Human 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2,5,2',5'-tetrachlorobiphenyl results in increased expression of ESM1 mRNA CTD PMID:36804509 ESM1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:71013 6480464 Tetrachlorodibenzodioxin results in decreased expression of ESM1 mRNA CTD PMID:21215274 ESM1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:71013 6480464 Tetrachlorodibenzodioxin results in increased expression of ESM1 mRNA CTD PMID:20959002 ESM1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737595 6480464 Tetrachlorodibenzodioxin results in decreased expression of ESM1 mRNA CTD PMID:20159946|PMID:21354282 ESM1 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO RGD:737595 6480464 2,2',4,4',5-brominated diphenyl ether affects the expression of ESM1 mRNA CTD PMID:38648751 ESM1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:71013 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESM1 mRNA CTD PMID:20959002 ESM1 Human 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:71013 6480464 [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased more ... CTD PMID:30744511 ESM1 Human 3,4,5,3',4',5'-Hexachlorobiphenyl multiple interactions ISO RGD:71013 6480464 [3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with Dibenzofurans, Polychlorinated co-treated with Polychlorinated Dibenzodioxins] results in increased more ... CTD PMID:30744511 ESM1 Human 3-chloropropane-1,2-diol decreases expression ISO RGD:71013 6480464 alpha-Chlorohydrin results in decreased expression of ESM1 mRNA CTD PMID:28522335 ESM1 Human 4,4'-sulfonyldiphenol increases expression ISO RGD:737595 6480464 bisphenol S results in increased expression of ESM1 mRNA CTD PMID:30951980 ESM1 Human 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol S co-treated with Fulvestrant] results in increased methylation of ESM1 gene CTD PMID:31601247 ESM1 Human acetamide increases expression ISO RGD:71013 6480464 acetamide results in increased expression of ESM1 mRNA CTD PMID:31881176 ESM1 Human acrylamide decreases expression ISO RGD:71013 6480464 Acrylamide results in decreased expression of ESM1 mRNA CTD PMID:28959563 ESM1 Human aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of ESM1 gene CTD PMID:27153756 ESM1 Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of ESM1 protein CTD PMID:18922099 ESM1 Human all-trans-retinoic acid multiple interactions ISO RGD:737595 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ESM1 mRNA CTD PMID:36189433 ESM1 Human allethrin multiple interactions ISO RGD:71013 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ... CTD PMID:34896426 ESM1 Human alpha-Zearalanol multiple interactions ISO RGD:71013 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of ESM1 mRNA CTD PMID:35163327 ESM1 Human ammonium chloride affects expression ISO RGD:71013 6480464 Ammonium Chloride affects the expression of ESM1 mRNA CTD PMID:16483693 ESM1 Human ampicillin decreases expression EXP 6480464 Ampicillin results in decreased expression of ESM1 mRNA CTD PMID:21632981 ESM1 Human aristolochic acid A multiple interactions ISO RGD:71013 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of ESM1 mRNA CTD PMID:23912714 ESM1 Human arsane affects expression EXP 6480464 Arsenic affects the expression of ESM1 protein CTD PMID:24675094 ESM1 Human arsane multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 ESM1 Human arsenic atom affects expression EXP 6480464 Arsenic affects the expression of ESM1 protein CTD PMID:24675094 ESM1 Human arsenic atom multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 ESM1 Human benzo[a]pyrene affects expression ISO RGD:737595 6480464 Benzo(a)pyrene affects the expression of ESM1 mRNA CTD PMID:20127859 ESM1 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of ESM1 promoter CTD PMID:27901495 ESM1 Human benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of ESM1 3' UTR CTD PMID:27901495 ESM1 Human benzo[a]pyrene increases expression ISO RGD:737595 6480464 Benzo(a)pyrene results in increased expression of ESM1 mRNA CTD PMID:22228805 ESM1 Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of ESM1 mRNA CTD PMID:22316170 ESM1 Human benzo[a]pyrene decreases expression ISO RGD:737595 6480464 Benzo(a)pyrene results in decreased expression of ESM1 mRNA CTD PMID:21569818 ESM1 Human benzo[a]pyrene increases expression ISO RGD:71013 6480464 Benzo(a)pyrene results in increased expression of ESM1 mRNA CTD PMID:21839799 ESM1 Human benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ESM1 mRNA CTD PMID:20382639 ESM1 Human benzo[b]fluoranthene decreases expression ISO RGD:737595 6480464 benzo(b)fluoranthene results in decreased expression of ESM1 mRNA CTD PMID:26377693 ESM1 Human Benzo[k]fluoranthene decreases expression ISO RGD:737595 6480464 benzo(k)fluoranthene results in decreased expression of ESM1 mRNA CTD PMID:26377693 ESM1 Human beta-naphthoflavone multiple interactions ISO RGD:71013 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ESM1 mRNA CTD PMID:18164116 ESM1 Human bisphenol A affects expression ISO RGD:71013 6480464 bisphenol A affects the expression of ESM1 mRNA CTD PMID:25181051 ESM1 Human bisphenol A decreases expression ISO RGD:71013 6480464 bisphenol A results in decreased expression of ESM1 mRNA CTD PMID:32145629|PMID:34947998 ESM1 Human bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ESM1 mRNA CTD PMID:29275510 ESM1 Human bisphenol A increases expression ISO RGD:737595 6480464 bisphenol A results in increased expression of ESM1 mRNA CTD PMID:30951980 ESM1 Human bisphenol A increases methylation ISO RGD:737595 6480464 bisphenol A results in increased methylation of ESM1 promoter CTD PMID:27312807 ESM1 Human bisphenol A increases methylation ISO RGD:71013 6480464 bisphenol A results in increased methylation of ESM1 gene CTD PMID:28505145 ESM1 Human bisphenol F increases expression ISO RGD:737595 6480464 bisphenol F results in increased expression of ESM1 mRNA CTD PMID:30951980 ESM1 Human cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of ESM1 mRNA CTD PMID:36321828 ESM1 Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of ESM1 mRNA CTD PMID:38568856 ESM1 Human carbon nanotube decreases expression ISO RGD:737595 6480464 Nanotubes, Carbon analog results in decreased expression of ESM1 mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681 ESM1 Human carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon analog results in increased expression of ESM1 mRNA; Nanotubes, Carbon results in increased more ... CTD PMID:25102311 ESM1 Human CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to ESM1 gene] CTD PMID:28238834 ESM1 Human chlorohydrocarbon multiple interactions ISO RGD:71013 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of more ... CTD PMID:30744511 ESM1 Human chloroprene decreases expression ISO RGD:737595 6480464 Chloroprene results in decreased expression of ESM1 mRNA CTD PMID:23125180 ESM1 Human chloroprene increases expression ISO RGD:71013 6480464 Chloroprene results in increased expression of ESM1 mRNA CTD PMID:23125180 ESM1 Human cholesterol multiple interactions ISO RGD:737595 6480464 [Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of ESM1 mRNA CTD PMID:22129739 ESM1 Human chromium(6+) multiple interactions EXP 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression more ... CTD PMID:38479592 ESM1 Human cisplatin multiple interactions EXP 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of ESM1 mRNA] CTD PMID:21858171 ESM1 Human clofibric acid affects expression ISO RGD:71013 6480464 Clofibric Acid affects the expression of ESM1 mRNA CTD PMID:17602206 ESM1 Human cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of ESM1 mRNA CTD PMID:19320972 ESM1 Human copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of ESM1 mRNA CTD PMID:19549813 ESM1 Human crocidolite asbestos decreases expression ISO RGD:737595 6480464 Asbestos, Crocidolite results in decreased expression of ESM1 mRNA CTD PMID:29279043 ESM1 Human cyhalothrin multiple interactions ISO RGD:71013 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ... CTD PMID:34896426 ESM1 Human cypermethrin multiple interactions ISO RGD:71013 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ... CTD PMID:34896426 ESM1 Human diallyl trisulfide increases expression EXP 6480464 diallyl trisulfide results in increased expression of ESM1 mRNA CTD PMID:34995734 ESM1 Human dibenz[a,h]anthracene decreases expression ISO RGD:737595 6480464 1,2,5,6-dibenzanthracene results in decreased expression of ESM1 mRNA CTD PMID:26377693 ESM1 Human diquat decreases expression ISO RGD:737595 6480464 Diquat results in decreased expression of ESM1 mRNA CTD PMID:36851058 ESM1 Human doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of ESM1 mRNA CTD PMID:29803840 ESM1 Human endosulfan increases expression ISO RGD:71013 6480464 Endosulfan results in increased expression of ESM1 mRNA CTD PMID:29391264 ESM1 Human fenvalerate multiple interactions ISO RGD:71013 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ... CTD PMID:34896426 ESM1 Human ferric oxide increases expression ISO RGD:71013 6480464 ferric oxide analog results in increased expression of ESM1 mRNA CTD PMID:38615722 ESM1 Human formaldehyde decreases expression EXP 6480464 Formaldehyde results in decreased expression of ESM1 mRNA CTD PMID:28937961 ESM1 Human fulvestrant multiple interactions EXP 6480464 [bisphenol S co-treated with Fulvestrant] results in increased methylation of ESM1 gene CTD PMID:31601247 ESM1 Human genistein decreases expression EXP 6480464 Genistein results in decreased expression of ESM1 mRNA CTD PMID:22228119 ESM1 Human genistein increases expression ISO RGD:737595 6480464 Genistein results in increased expression of ESM1 mRNA CTD PMID:32186404 ESM1 Human lead diacetate decreases expression ISO RGD:71013 6480464 lead acetate results in decreased expression of ESM1 mRNA CTD PMID:22641619 ESM1 Human lidocaine decreases expression ISO RGD:71013 6480464 Lidocaine results in decreased expression of ESM1 mRNA CTD PMID:35283115 ESM1 Human lipopolysaccharide multiple interactions ISO RGD:737595 6480464 Estradiol promotes the reaction [Lipopolysaccharides results in increased expression of ESM1 mRNA] CTD PMID:16977382 ESM1 Human lipopolysaccharide increases expression ISO RGD:737595 6480464 Lipopolysaccharides results in increased expression of ESM1 mRNA CTD PMID:16977382 ESM1 Human manganese atom multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 ESM1 Human manganese(0) multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 ESM1 Human manganese(II) chloride multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 ESM1 Human methylisothiazolinone increases expression EXP 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of ESM1 mRNA CTD PMID:31629900 ESM1 Human methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of ESM1 mRNA CTD PMID:23179753 ESM1 Human methylmercury chloride multiple interactions ISO RGD:71013 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of more ... CTD PMID:30744511 ESM1 Human mifepristone increases expression EXP 6480464 Mifepristone results in increased expression of ESM1 mRNA CTD PMID:17584828 ESM1 Human mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of ESM1 mRNA CTD PMID:36695872 ESM1 Human mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:737595 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ESM1 mRNA CTD PMID:36189433 ESM1 Human N-nitrosodiethylamine multiple interactions ISO RGD:71013 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ESM1 mRNA CTD PMID:18164116 ESM1 Human N-nitrosodiethylamine increases expression ISO RGD:737595 6480464 Diethylnitrosamine results in increased expression of ESM1 mRNA CTD PMID:24535843 ESM1 Human nevirapine increases expression ISO RGD:71013 6480464 Nevirapine metabolite results in increased expression of ESM1 mRNA; Nevirapine results in increased expression of more ... CTD PMID:23947594 ESM1 Human ozone multiple interactions ISO RGD:737595 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... CTD PMID:27106289|PMID:34911549 ESM1 Human paracetamol affects expression ISO RGD:737595 6480464 Acetaminophen affects the expression of ESM1 mRNA CTD PMID:17562736 ESM1 Human paraquat increases expression ISO RGD:71013 6480464 Paraquat results in increased expression of ESM1 mRNA CTD PMID:32680482 ESM1 Human PD 0325901 multiple interactions EXP 6480464 [mirdametinib co-treated with (+)-JQ1 compound] results in decreased expression of ESM1 mRNA CTD PMID:25119042 ESM1 Human PD 0325901 decreases expression EXP 6480464 mirdametinib results in decreased expression of ESM1 mRNA CTD PMID:25119042 ESM1 Human perfluorononanoic acid decreases expression EXP 6480464 perfluoro-n-nonanoic acid results in decreased expression of ESM1 protein CTD PMID:32916415 ESM1 Human perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:737595 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ESM1 mRNA; [perfluorooctane sulfonic more ... CTD PMID:36331819 ESM1 Human perfluorooctanoic acid multiple interactions ISO RGD:71013 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of ESM1 mRNA CTD PMID:35163327 ESM1 Human phenformin increases expression ISO RGD:71013 6480464 Phenformin results in increased expression of ESM1 mRNA CTD PMID:31324951 ESM1 Human phenobarbital multiple interactions ISO RGD:737595 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ESM1 mRNA] CTD PMID:19482888 ESM1 Human phenobarbital increases expression ISO RGD:737595 6480464 Phenobarbital results in increased expression of ESM1 mRNA CTD PMID:19482888 ESM1 Human pirinixic acid increases expression ISO RGD:737595 6480464 pirinixic acid results in increased expression of ESM1 mRNA CTD PMID:23811191 ESM1 Human piroxicam multiple interactions EXP 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of ESM1 mRNA] CTD PMID:21858171 ESM1 Human piroxicam decreases expression EXP 6480464 Piroxicam results in decreased expression of ESM1 mRNA CTD PMID:21858171 ESM1 Human pyrethrins decreases expression ISO RGD:71013 6480464 Pyrethrins results in decreased expression of ESM1 protein CTD PMID:34896426 ESM1 Human quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of ESM1 mRNA CTD PMID:21632981 ESM1 Human quinolin-8-ol decreases expression EXP 6480464 Oxyquinoline results in decreased expression of ESM1 mRNA CTD PMID:21632981 ESM1 Human rotenone increases expression ISO RGD:71013 6480464 Rotenone results in increased expression of ESM1 mRNA CTD PMID:28374803 ESM1 Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of ESM1 mRNA CTD PMID:23806026 ESM1 Human sodium arsenite multiple interactions EXP 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 ESM1 Human sodium arsenite decreases expression ISO RGD:737595 6480464 sodium arsenite results in decreased expression of ESM1 mRNA CTD PMID:37682722 ESM1 Human tamoxifen increases expression ISO RGD:737595 6480464 Tamoxifen results in increased expression of ESM1 mRNA CTD PMID:25123088 ESM1 Human tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of ESM1 mRNA CTD PMID:15336504 ESM1 Human tetrachloro-1,4-benzoquinone increases expression EXP 6480464 Chloranil results in increased expression of ESM1 mRNA CTD PMID:24214992 ESM1 Human tetrachloroethene increases expression ISO RGD:737595 6480464 Tetrachloroethylene results in increased expression of ESM1 mRNA CTD PMID:28973375 ESM1 Human tetrachloromethane decreases expression ISO RGD:737595 6480464 Carbon Tetrachloride results in decreased expression of ESM1 mRNA CTD PMID:31919559 ESM1 Human thioacetamide increases expression ISO RGD:71013 6480464 Thioacetamide results in increased expression of ESM1 mRNA CTD PMID:23411599|PMID:34492290 ESM1 Human titanium dioxide increases expression ISO RGD:737595 6480464 titanium dioxide results in increased expression of ESM1 mRNA CTD PMID:23557971 ESM1 Human trichloroethene decreases expression ISO RGD:71013 6480464 Trichloroethylene results in decreased expression of ESM1 mRNA CTD PMID:33387578 ESM1 Human triptonide increases expression ISO RGD:737595 6480464 triptonide results in increased expression of ESM1 mRNA CTD PMID:33045310 ESM1 Human vincaleukoblastine decreases expression ISO RGD:71013 6480464 Vinblastine results in decreased expression of ESM1 mRNA CTD PMID:20624997 ESM1 Human vincristine decreases expression ISO RGD:71013 6480464 Vincristine results in decreased expression of ESM1 mRNA CTD PMID:20624997