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Gene: WNT4 (Wnt family member 4) Homo sapiens
Symbol: WNT4
Name: Wnt family member 4
Description: Exhibits receptor ligand activity. Involved in several processes, including animal organ development; positive regulation of ossification; and regulation of hormone biosynthetic process. Localizes to cytoplasm and extracellular space. Implicated in Mullerian aplasia and hyperandrogenism. Biomarker of endometrial carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: SERKAL; wingless-type MMTV integration site family member 4; wingless-type MMTV integration site family, member 4; WNT-4
Mus musculus (house mouse) : Wnt4 (wingless-type MMTV integration site family, member 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Wnt4 (Wnt family member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnt4 (Wnt family member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : WNT4 (Wnt family member 4)
Canis lupus familiaris (dog) : WNT4 (Wnt family member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnt4 (Wnt family member 4)
Sus scrofa (pig) : WNT4 (Wnt family member 4)
Chlorocebus sabaeus (African green monkey) : WNT4 (Wnt family member 4)
Heterocephalus glaber (naked mole-rat) : Wnt4 (Wnt family member 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl122,117,313 - 22,143,969 (-)EnsemblGRCh38hg38GRCh38
GRCh38122,117,308 - 22,143,981 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37122,443,798 - 22,470,474 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,316,385 - 22,342,106 (-)NCBINCBI36hg18NCBI36
Build 34122,191,504 - 22,214,916NCBI
Celera120,766,732 - 20,792,452 (-)NCBI
Cytogenetic Map1p36.12NCBI
HuRef120,687,456 - 20,707,677 (-)NCBIHuRef
CHM1_1122,556,295 - 22,576,527 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on WNT4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733867
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.