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Gene: INPP5B (inositol polyphosphate-5-phosphatase B) Homo sapiens
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Symbol: INPP5B
Name: inositol polyphosphate-5-phosphatase B
Description: Exhibits inositol-1,4,5-trisphosphate 5-phosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in phosphatidylinositol dephosphorylation. Localizes to the cytosol and membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5PTase; 75 kDa inositol polyphosphate-5-phosphatase; inositol polyphosphate-5-phosphatase, 75kD; inositol polyphosphate-5-phosphatase, 75kDa; MGC65156; MGC71303; phosphoinositide 5-phosphatase; type II inositol 1,4,5-trisphosphate 5-phosphatase; type II inositol-1,4,5-trisphosphate 5-phosphatase
Orthologs:
Mus musculus (house mouse) : Inpp5b (inositol polyphosphate-5-phosphatase B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Inpp5b (inositol polyphosphate-5-phosphatase B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inpp5b (inositol polyphosphate-5-phosphatase B)
Pan paniscus (bonobo/pygmy chimpanzee) : INPP5B (inositol polyphosphate-5-phosphatase B)
Canis lupus familiaris (dog) : INPP5B (inositol polyphosphate-5-phosphatase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inpp5b (inositol polyphosphate-5-phosphatase B)
Sus scrofa (pig) : INPP5B (inositol polyphosphate-5-phosphatase B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38137,860,697 - 37,947,095 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37138,326,369 - 38,412,729 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36138,098,956 - 38,185,316 (-)NCBINCBI36hg18NCBI36
Build 34137,995,461 - 38,081,786NCBI
Celera136,604,192 - 36,690,446 (-)NCBI
Cytogenetic Map1p34.3NCBI
HuRef136,444,364 - 36,530,434 (-)NCBIHuRef
CHM1_1138,442,163 - 38,528,531 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on INPP5B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1342739
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.