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Gene: BAG4 (BAG cochaperone 4) Homo sapiens
Symbol: BAG4
Name: BAG cochaperone 4
Description: Exhibits ubiquitin protein ligase binding activity. Involved in cellular response to tumor necrosis factor and negative regulation of protein targeting to mitochondrion. Localizes to the cytosol; nucleus; and plasma membrane. Biomarker of pancreatic cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BAG family molecular chaperone regulator 4; BAG-4; BAG-family molecular chaperone regulator-4; bcl-2-associated athanogene 4; BCL2 associated athanogene 4; BCL2-associated athanogene 4; DKFZp586O2022; silencer of death domains; SODD
Mus musculus (house mouse) : Bag4 (BCL2-associated athanogene 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bag4 (BAG cochaperone 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bag4 (BAG cochaperone 4)
Pan paniscus (bonobo/pygmy chimpanzee) : BAG4 (BAG cochaperone 4)
Canis lupus familiaris (dog) : BAG4 (BAG cochaperone 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bag4 (BAG cochaperone 4)
Sus scrofa (pig) : BAG4 (BAG cochaperone 4)
Chlorocebus sabaeus (green monkey) : BAG4 (BAG cochaperone 4)
Heterocephalus glaber (naked mole-rat) : Bag4 (BAG cochaperone 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl838,176,533 - 38,213,301 (+)Ensembl
GRCh38838,176,855 - 38,213,301 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37838,034,106 - 38,070,819 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36838,153,263 - 38,187,694 (+)NCBINCBI36hg18NCBI36
Build 34838,153,262 - 38,187,694NCBI
Celera836,986,642 - 37,021,084 (+)NCBI
Cytogenetic Map8p11.23NCBI
HuRef836,568,494 - 36,604,926 (+)NCBIHuRef
CHM1_1838,236,107 - 38,272,816 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BAG4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350570
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.