H4C3 (H4 clustered histone 3) - Rat Genome Database

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Gene: H4C3 (H4 clustered histone 3) Homo sapiens
Analyze
Symbol: H4C3
Name: H4 clustered histone 3
RGD ID: 1352928
HGNC Page HGNC
Description: Enables protein domain specific binding activity. Involved in chromatin assembly and negative regulation of megakaryocyte differentiation. Located in CENP-A containing nucleosome and nuclear chromosome. Part of nucleosome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: dJ221C16.1; H4 histone family, member G; H4-16; H4/g; H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C2; H4C4; H4C5; H4C6; H4C8; H4C9; H4FG; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; HIST2H4A; HIST2H4B; HIST4H4; histone 1, H4c; histone cluster 1 H4 family member c; histone cluster 1, H4c; histone H4; TEVANED1
RGD Orthologs
Rat
Squirrel
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38626,103,933 - 26,104,337 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl626,103,933 - 26,104,337 (+)EnsemblGRCh38hg38GRCh38
GRCh37626,104,161 - 26,104,565 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,212,140 - 26,212,544 (+)NCBINCBI36hg18NCBI36
Build 34626,212,154 - 26,212,544NCBI
Celera627,333,446 - 27,333,850 (+)NCBI
Cytogenetic Map6p22.2NCBI
HuRef626,047,237 - 26,047,626 (+)NCBIHuRef
CHM1_1626,106,435 - 26,106,824 (+)NCBICHM1_1
T2T-CHM13v2.0625,972,081 - 25,972,485 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (EXP)
2,3-dimethoxynaphthalene-1,4-dione  (EXP)
2-methylcholine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
5-fluorouracil  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP)
antimony(0)  (EXP)
arsenous acid  (EXP)
atrazine  (EXP)
Azaspiracid  (EXP)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[e]pyrene  (EXP)
berberine  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP)
bisphenol F  (EXP)
cadmium dichloride  (EXP)
calcitriol  (EXP)
carbon nanotube  (EXP)
chlorambucil  (EXP)
chloropicrin  (EXP)
chromium atom  (EXP)
cisplatin  (EXP)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
cyclosporin A  (EXP)
cytarabine  (EXP)
dexamethasone  (EXP)
diarsenic trioxide  (EXP)
dicrotophos  (EXP)
dinophysistoxin 1  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (EXP)
disodium selenite  (EXP)
doxorubicin  (EXP)
ethanol  (EXP)
gemcitabine  (EXP)
hydrogen peroxide  (EXP)
hydroquinone  (EXP)
indometacin  (EXP)
irinotecan  (EXP)
Licochalcone B  (EXP)
lucanthone  (EXP)
menadione  (EXP)
mercury atom  (EXP)
mercury(0)  (EXP)
methapyrilene  (EXP)
methylmercury chloride  (EXP)
N-Nitrosopyrrolidine  (EXP)
nickel dichloride  (EXP)
okadaic acid  (EXP)
palbociclib  (EXP)
paracetamol  (EXP)
piroxicam  (EXP)
potassium dichromate  (EXP)
quercetin  (EXP)
sodium arsenite  (EXP)
tamibarotene  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (EXP)
troglitazone  (EXP)
urethane  (EXP)
versicolorin A  (EXP)
vincristine  (EXP)
zidovudine  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Pipeline to import KEGG annotations from KEGG into RGD
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3035717   PMID:7626218   PMID:9119399   PMID:9439656   PMID:9540062   PMID:9566873   PMID:10220385   PMID:11080476   PMID:11689053   PMID:12408966   PMID:12477932   PMID:14585971  
PMID:14657027   PMID:14718166   PMID:15161933   PMID:15556009   PMID:15670829   PMID:15933069   PMID:16415788   PMID:16917504   PMID:17540172   PMID:17675446   PMID:18051367   PMID:18404153  
PMID:18408754   PMID:18474616   PMID:18571423   PMID:19135898   PMID:19199708   PMID:19410544   PMID:19494831   PMID:19498464   PMID:19710015   PMID:19738201   PMID:19862764   PMID:19946888  
PMID:20000738   PMID:20224553   PMID:20458337   PMID:20498094   PMID:20525793   PMID:20587610   PMID:20618440   PMID:20686565   PMID:20709061   PMID:20739937   PMID:20800603   PMID:20951943  
PMID:21081503   PMID:21085121   PMID:21145461   PMID:21164480   PMID:21478274   PMID:21596426   PMID:21630459   PMID:21636898   PMID:21743476   PMID:21800051   PMID:21812398   PMID:21873635  
PMID:21888893   PMID:21907836   PMID:21983900   PMID:22145905   PMID:22343720   PMID:22368283   PMID:22373579   PMID:22615379   PMID:22623428   PMID:22658674   PMID:22681889   PMID:23071334  
PMID:23075851   PMID:23142979   PMID:23376485   PMID:23377543   PMID:23533145   PMID:23760478   PMID:23831576   PMID:23979707   PMID:24183680   PMID:24311584   PMID:24360279   PMID:24361270  
PMID:24525235   PMID:24596249   PMID:24699735   PMID:24711643   PMID:24726341   PMID:24981860   PMID:25281266   PMID:25416956   PMID:25556234   PMID:25579814   PMID:25615412   PMID:25619998  
PMID:25651062   PMID:25910212   PMID:25963833   PMID:26167883   PMID:26496610   PMID:26694698   PMID:26725010   PMID:26912361   PMID:27153538   PMID:28514442   PMID:28902428   PMID:28920961  
PMID:28977666   PMID:29507755   PMID:29676528   PMID:29844126   PMID:30021884   PMID:30554943   PMID:31142837   PMID:31759698   PMID:31790919   PMID:32296183   PMID:32545337   PMID:32814053  
PMID:33080218   PMID:33857403   PMID:33961781  


Genomics

Comparative Map Data
H4C3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38626,103,933 - 26,104,337 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl626,103,933 - 26,104,337 (+)EnsemblGRCh38hg38GRCh38
GRCh37626,104,161 - 26,104,565 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,212,140 - 26,212,544 (+)NCBINCBI36hg18NCBI36
Build 34626,212,154 - 26,212,544NCBI
Celera627,333,446 - 27,333,850 (+)NCBI
Cytogenetic Map6p22.2NCBI
HuRef626,047,237 - 26,047,626 (+)NCBIHuRef
CHM1_1626,106,435 - 26,106,824 (+)NCBICHM1_1
T2T-CHM13v2.0625,972,081 - 25,972,485 (+)NCBI
H4c3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04170,144,871 - 170,145,311 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4170,144,951 - 170,145,262 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04234,404,771 - 234,406,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map4q43NCBI
LOC101972801
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049461,667,931 - 1,668,479 (-)NCBI
SpeTri2.0NW_0049366711,953,045 - 1,953,612 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0

Position Markers
RH103644  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37626,102,641 - 26,102,773UniSTSGRCh37
Build 36626,210,620 - 26,210,752RGDNCBI36
Celera627,331,925 - 27,332,057RGD
Cytogenetic Map6p22.1UniSTS
HuRef626,045,701 - 26,045,833UniSTS
GeneMap99-GB4 RH Map6105.5UniSTS
RH103651  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37626,104,387 - 26,104,516UniSTSGRCh37
Build 36626,212,366 - 26,212,495RGDNCBI36
Celera627,333,672 - 27,333,801RGD
Cytogenetic Map6p22.1UniSTS
HuRef626,047,448 - 26,047,577UniSTS
GeneMap99-GB4 RH Map6105.76UniSTS
RH70851  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37626,104,483 - 26,104,684UniSTSGRCh37
Build 36626,212,462 - 26,212,663RGDNCBI36
Celera627,333,768 - 27,333,969RGD
Cytogenetic Map6p22.1UniSTS
HuRef626,047,544 - 26,047,745UniSTS
GeneMap99-GB4 RH Map6105.76UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENST00000377803   ⟹   ENSP00000367034
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl626,103,933 - 26,104,337 (+)Ensembl
RefSeq Acc Id: NM_003542   ⟹   NP_003533
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38626,103,933 - 26,104,337 (+)NCBI
GRCh37626,104,176 - 26,104,565 (+)ENTREZGENE
Build 36626,212,155 - 26,212,544 (+)NCBI Archive
Celera627,333,446 - 27,333,850 (+)RGD
HuRef626,047,237 - 26,047,626 (+)ENTREZGENE
CHM1_1626,106,435 - 26,106,824 (+)NCBI
T2T-CHM13v2.0625,972,081 - 25,972,485 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_003533   ⟸   NM_003542
- UniProtKB: P62805 (UniProtKB/Swiss-Prot),   B2R4R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000367034   ⟸   ENST00000377803
Protein Domains
TAF

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62805-F1-model_v2 AlphaFold P62805 1-103 view protein structure

Promoters
RGD ID:6804312
Promoter ID:HG_KWN:52580
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000377803
Position:
Human AssemblyChrPosition (strand)Source
Build 36626,212,019 - 26,212,519 (+)MPROMDB
RGD ID:6849404
Promoter ID:EP49012
Type:single initiation site
Name:HS_HIST1H4C
Description:Histone H4c.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 220; Mammalian testicular histone H4 gene.
Tissues & Cell Lines:testicular and nontesticular cells
Experiment Methods:Nuclease protection with homologous sequence ladder
Position:
Human AssemblyChrPosition (strand)Source
Build 36626,212,141 - 26,212,201EPD

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p22.3-21.33(chr6:18120520-30767516)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|See cases [RCV000052180] Chr6:18120520..30767516 [GRCh38]
Chr6:18120751..30735293 [GRCh37]
Chr6:18228730..30843272 [NCBI36]
Chr6:6p22.3-21.33
pathogenic
GRCh38/hg38 6p25.2-21.33(chr6:3224310-30657190)x3 copy number gain See cases [RCV000138956] Chr6:3224310..30657190 [GRCh38]
Chr6:3224544..30624967 [GRCh37]
Chr6:3169543..30732946 [NCBI36]
Chr6:6p25.2-21.33
pathogenic
GRCh38/hg38 6p22.2(chr6:25991402-26280693)x3 copy number gain See cases [RCV000139521] Chr6:25991402..26280693 [GRCh38]
Chr6:25991630..26280921 [GRCh37]
Chr6:26099609..26388900 [NCBI36]
Chr6:6p22.2
likely benign
GRCh38/hg38 6p22.2(chr6:25991391-26116829)x3 copy number gain See cases [RCV000140950] Chr6:25991391..26116829 [GRCh38]
Chr6:25991619..26117057 [GRCh37]
Chr6:26099598..26225036 [NCBI36]
Chr6:6p22.2
likely benign
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3
pathogenic
GRCh37/hg19 6p22.2(chr6:26104332-26365573)x4 copy number gain Ductal breast carcinoma [RCV000207323] Chr6:26104332..26365573 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25839165-26536884)x4 copy number gain See cases [RCV000447433] Chr6:25839165..26536884 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.2(chr6:25851789-26319486)x3 copy number gain not provided [RCV000682656] Chr6:25851789..26319486 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.2(chr6:26067079-26207758)x1 copy number loss not provided [RCV000849592] Chr6:26067079..26207758 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:26067580-26306202)x3 copy number gain not provided [RCV000849663] Chr6:26067580..26306202 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3 copy number gain not provided [RCV000847447] Chr6:25996066..26303969 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25896585-26287389)x4 copy number gain not provided [RCV000845790] Chr6:25896585..26287389 [GRCh37]
Chr6:6p22.2
uncertain significance
NM_003542.4(H4C3):c.105T>C (p.Ile35=) single nucleotide variant not provided [RCV001644006] Chr6:26104052 [GRCh38]
Chr6:26104280 [GRCh37]
Chr6:6p22.2
benign
NM_003542.4(H4C3):c.271C>T (p.Leu91=) single nucleotide variant not provided [RCV000888597] Chr6:26104218 [GRCh38]
Chr6:26104446 [GRCh37]
Chr6:6p22.2
benign
NM_003542.4(H4C3):c.207C>T (p.Asp69=) single nucleotide variant not provided [RCV001541500] Chr6:26104154 [GRCh38]
Chr6:26104382 [GRCh37]
Chr6:6p22.2
benign
NM_003542.4(H4C3):c.273A>G (p.Leu91=) single nucleotide variant not provided [RCV001710965] Chr6:26104220 [GRCh38]
Chr6:26104448 [GRCh37]
Chr6:6p22.2
benign
NM_003542.4(H4C3):c.274A>C (p.Lys92Gln) single nucleotide variant HIST1H4C-associated disorder [RCV001254079] Chr6:26104221 [GRCh38]
Chr6:26104449 [GRCh37]
Chr6:6p22.2
pathogenic
GRCh37/hg19 6p22.2(chr6:26046566-26670193)x3 copy number gain not provided [RCV001258882] Chr6:26046566..26670193 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:26090243-26265667)x3 copy number gain not provided [RCV001258883] Chr6:26090243..26265667 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25839165-26536884) copy number gain not specified [RCV002053562] Chr6:25839165..26536884 [GRCh37]
Chr6:6p22.2
uncertain significance
NM_003542.4(H4C3):c.275A>G (p.Lys92Arg) single nucleotide variant Tessadori-van Haaften neurodevelopmental syndrome 1 [RCV001838837] Chr6:26104222 [GRCh38]
Chr6:26104450 [GRCh37]
Chr6:6p22.2
pathogenic
GRCh37/hg19 6p22.2(chr6:26008259-26168230)x1 copy number loss not provided [RCV001834493] Chr6:26008259..26168230 [GRCh37]
Chr6:6p22.2
pathogenic

Additional Information

Database Acc Id Source(s)
COSMIC H4C3 COSMIC
Ensembl Genes ENSG00000158406 UniProtKB/Swiss-Prot
  ENSG00000197061 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000197238 UniProtKB/Swiss-Prot
  ENSG00000197837 UniProtKB/Swiss-Prot
  ENSG00000270276 UniProtKB/Swiss-Prot
  ENSG00000270882 UniProtKB/Swiss-Prot
  ENSG00000273542 UniProtKB/Swiss-Prot
  ENSG00000274618 UniProtKB/Swiss-Prot
  ENSG00000275126 UniProtKB/Swiss-Prot
  ENSG00000276180 UniProtKB/Swiss-Prot
  ENSG00000276966 UniProtKB/Swiss-Prot
  ENSG00000277157 UniProtKB/Swiss-Prot
  ENSG00000278637 UniProtKB/Swiss-Prot
  ENSG00000278705 UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000244537 UniProtKB/Swiss-Prot
  ENSP00000347168 UniProtKB/Swiss-Prot
  ENSP00000350767 UniProtKB/Swiss-Prot
  ENSP00000366956 UniProtKB/Swiss-Prot
  ENSP00000366974 UniProtKB/Swiss-Prot
  ENSP00000367034 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000443017 UniProtKB/Swiss-Prot
  ENSP00000462355 UniProtKB/Swiss-Prot
  ENSP00000462667 UniProtKB/Swiss-Prot
  ENSP00000478519 UniProtKB/Swiss-Prot
  ENSP00000478786 UniProtKB/Swiss-Prot
  ENSP00000479106 UniProtKB/Swiss-Prot
  ENSP00000479461 UniProtKB/Swiss-Prot
  ENSP00000479794 UniProtKB/Swiss-Prot
  ENSP00000480960 UniProtKB/Swiss-Prot
  ENSP00000481343 UniProtKB/Swiss-Prot
  ENSP00000481486 UniProtKB/Swiss-Prot
  ENSP00000481507 UniProtKB/Swiss-Prot
  ENSP00000482412 UniProtKB/Swiss-Prot
  ENSP00000484789 UniProtKB/Swiss-Prot
  ENSP00000489319 UniProtKB/Swiss-Prot
  ENSP00000489567 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000244537 UniProtKB/Swiss-Prot
  ENST00000355057 UniProtKB/Swiss-Prot
  ENST00000358064 UniProtKB/Swiss-Prot
  ENST00000377727 UniProtKB/Swiss-Prot
  ENST00000377745 UniProtKB/Swiss-Prot
  ENST00000377803 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000539745 UniProtKB/Swiss-Prot
  ENST00000578186 UniProtKB/Swiss-Prot
  ENST00000579512 UniProtKB/Swiss-Prot
  ENST00000611927 UniProtKB/Swiss-Prot
  ENST00000612061 UniProtKB/Swiss-Prot
  ENST00000613412 UniProtKB/Swiss-Prot
  ENST00000614247 UniProtKB/Swiss-Prot
  ENST00000614272 UniProtKB/Swiss-Prot
  ENST00000615164 UniProtKB/Swiss-Prot
  ENST00000615353 UniProtKB/Swiss-Prot
  ENST00000617569 UniProtKB/Swiss-Prot
  ENST00000618193 UniProtKB/Swiss-Prot
  ENST00000618305 UniProtKB/Swiss-Prot
  ENST00000621520 UniProtKB/Swiss-Prot
  ENST00000634560 UniProtKB/Swiss-Prot
  ENST00000634956 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000158406 GTEx
  ENSG00000197061 GTEx
  ENSG00000197238 GTEx
  ENSG00000197837 GTEx
  ENSG00000270276 GTEx
  ENSG00000270882 GTEx
  ENSG00000273542 GTEx
  ENSG00000274618 GTEx
  ENSG00000275126 GTEx
  ENSG00000276180 GTEx
  ENSG00000276966 GTEx
  ENSG00000277157 GTEx
  ENSG00000278637 GTEx
  ENSG00000278705 GTEx
HGNC ID HGNC:4787 ENTREZGENE
Human Proteome Map H4C3 Human Proteome Map
InterPro CENP-T/H4_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H4_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAF_TATA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:121504 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:554313 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8359 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8361 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8362 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8363 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8364 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8365 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8366 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8367 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8368 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hsa:8370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 8364 ENTREZGENE
OMIM 602827 OMIM
  619758 OMIM
Pfam CENP-T_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA29162 PharmGKB
PRINTS HISTONEH4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HISTONE_H4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47113 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2R4R0 ENTREZGENE, UniProtKB/TrEMBL
  H4_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A2VCL0 UniProtKB/Swiss-Prot
  P02304 UniProtKB/Swiss-Prot
  P02305 UniProtKB/Swiss-Prot
  Q6DRA9 UniProtKB/Swiss-Prot
  Q6FGB8 UniProtKB/Swiss-Prot
  Q6NWP7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-30 H4C3  H4 clustered histone 3  HIST1H4C  histone cluster 1 H4 family member c  Symbol and/or name change 5135510 APPROVED
2016-08-23 HIST1H4C  histone cluster 1 H4 family member c  HIST1H4C  histone cluster 1, H4c  Symbol and/or name change 5135510 APPROVED