SEMA3G (semaphorin 3G) - Rat Genome Database

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Gene: SEMA3G (semaphorin 3G) Homo sapiens
Analyze
Symbol: SEMA3G
Name: semaphorin 3G
RGD ID: 1601989
HGNC Page HGNC:30400
Description: Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon extension; neural crest cell migration; and semaphorin-plexin signaling pathway. Located in extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: FLJ00014; MGC119473; sem2; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G; semaphorin sem2; semaphorin-3G
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,433,035 - 52,445,103 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,433,035 - 52,445,103 (-)EnsemblGRCh38hg38GRCh38
GRCh37352,467,051 - 52,479,119 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,442,308 - 52,454,083 (-)NCBINCBI36Build 36hg18NCBI36
Celera352,446,585 - 52,458,288 (-)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef352,529,926 - 52,541,701 (-)NCBIHuRef
CHM1_1352,419,717 - 52,431,420 (-)NCBICHM1_1
T2T-CHM13v2.0352,466,008 - 52,478,004 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SEMA3GHumancongenital disorder of glycosylation In  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital disorder of glycosylation type 1NClinVarPMID:28492532

1 to 20 of 84 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SEMA3GHuman1,1-dichloroethene decreases expressionISOSema3g (Mus musculus)6480464vinylidene chloride results in decreased expression of SEMA3G mRNACTDPMID:26682919
SEMA3GHuman1,2-dichloroethane increases expressionISOSema3g (Mus musculus)6480464ethylene dichloride results in increased expression of SEMA3G mRNACTDPMID:28960355
SEMA3GHuman1,2-dimethylhydrazine increases expressionISOSema3g (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of SEMA3G mRNACTDPMID:22206623
SEMA3GHuman17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of SEMA3G mRNACTDPMID:31614463
SEMA3GHuman2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of SEMA3G mRNACTDPMID:20106945
SEMA3GHuman2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSema3g (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of SEMA3G mRNACTDPMID:26377647
SEMA3GHuman2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOSema3g (Mus musculus)64804642 more ...CTDPMID:38648751
SEMA3GHuman3,3',4,4',5-pentachlorobiphenyl decreases expressionISOSema3g (Rattus norvegicus)64804643 more ...CTDPMID:32119087
SEMA3GHuman3-isobutyl-1-methyl-7H-xanthine multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of SEMA3G mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SEMA3G mRNACTDPMID:28628672
SEMA3GHuman4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of SEMA3G mRNACTDPMID:27685785
SEMA3GHuman4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of SEMA3G mRNACTDPMID:28628672
SEMA3GHuman6-propyl-2-thiouracil decreases expressionISOSema3g (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of SEMA3G mRNACTDPMID:24780913
SEMA3GHumanacrylamide decreases expressionISOSema3g (Rattus norvegicus)6480464Acrylamide results in decreased expression of SEMA3G mRNACTDPMID:28959563
SEMA3GHumanacrylamide increases expressionISOSema3g (Mus musculus)6480464Acrylamide results in increased expression of SEMA3G mRNACTDPMID:30807115
SEMA3GHumanactinomycin D multiple interactionsEXP 6480464[Dactinomycin co-treated with nutlin 3] results in increased expression of SEMA3G mRNACTDPMID:38460933
SEMA3GHumanafimoxifene decreases expressionISOSema3g (Mus musculus)6480464afimoxifene results in decreased expression of SEMA3G mRNACTDPMID:26879975
SEMA3GHumanaflatoxin B1 affects methylationEXP 6480464Aflatoxin B1 affects the methylation of SEMA3G intronCTDPMID:30157460
SEMA3GHumanAflatoxin B2 alpha increases methylationEXP 6480464aflatoxin B2 results in increased methylation of SEMA3G 3' UTRCTDPMID:30157460
SEMA3GHumanall-trans-retinoic acid multiple interactionsISOSema3g (Mus musculus)6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SEMA3G mRNACTDPMID:36189433
SEMA3GHumanall-trans-retinoic acid decreases expressionISOSema3g (Mus musculus)6480464Tretinoin results in decreased expression of SEMA3G mRNACTDPMID:36189433

1 to 20 of 84 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SEMA3GHumanaxon guidance involved_inIBAFB:FBgn0011259 more ...150520179 GO_CentralGO_REF:0000033
SEMA3GHumannegative chemotaxis involved_inIBAFB:FBgn0011260 more ...150520179 GO_CentralGO_REF:0000033
SEMA3GHumannegative regulation of axon extension involved_inISSUniProtKB:Q4LFA9150520179 UniProtGO_REF:0000024
SEMA3GHumannegative regulation of axon extension involved_inIEAUniProtKB:Q4LFA9 and ensembl:ENSMUSP00000087643150520179 EnsemblGO_REF:0000107
SEMA3GHumanneural crest cell migration involved_inIBAMGI:107557 more ...150520179 GO_CentralGO_REF:0000033
SEMA3GHumanpositive regulation of cell migration involved_inIBAMGI:107556 more ...150520179 GO_CentralGO_REF:0000033
SEMA3GHumansemaphorin-plexin signaling pathway involved_inIBAFB:FBgn0011259 more ...150520179 GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SEMA3GHumanextracellular exosome located_inHDA 150520179 PMID:19199708UniProtPMID:19199708
SEMA3GHumanextracellular region located_inIEAUniProtKB-SubCell:SL-0243150520179 UniProtGO_REF:0000044
SEMA3GHumanextracellular region located_inIEAUniProtKB-KW:KW-0964150520179 UniProtGO_REF:0000043
SEMA3GHumanplasma membrane is_active_inIBAMGI:107559 more ...150520179 GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
SEMA3GHumanchemorepellent activity enablesIBAMGI:107558 more ...150520179 GO_CentralGO_REF:0000033
SEMA3GHumanneuropilin binding enablesIBAMGI:107558 more ...150520179 GO_CentralGO_REF:0000033
SEMA3GHumanprotein binding enablesIPIUniProtKB:Q9BSY9150520179 PMID:32296183IntActPMID:32296183
SEMA3GHumansemaphorin receptor binding enablesIEAInterPro:IPR027231150520179 InterProGO_REF:0000002
SEMA3GHumansemaphorin receptor binding enablesIBAMGI:107556 more ...150520179 GO_CentralGO_REF:0000033
SEMA3GHumansignaling receptor binding enablesIEAUniProtKB:Q4LFA9 and ensembl:ENSMUSP00000087643150520179 EnsemblGO_REF:0000107
SEMA3GHumansignaling receptor binding enablesISSUniProtKB:Q4LFA9150520179 UniProtGO_REF:0000024


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11214971   PMID:12477932   PMID:14702039   PMID:15146197   PMID:15489334   PMID:18781179   PMID:18818766   PMID:19199708   PMID:19913121   PMID:20628086   PMID:20947821   PMID:21873635  
PMID:21926972   PMID:22562223   PMID:23974872   PMID:25335934   PMID:26598620   PMID:27180624   PMID:32296183   PMID:32452055   PMID:32513696   PMID:32807901   PMID:33586674   PMID:34857952  
PMID:37633476   PMID:38795838  



SEMA3G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,433,035 - 52,445,103 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,433,035 - 52,445,103 (-)EnsemblGRCh38hg38GRCh38
GRCh37352,467,051 - 52,479,119 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,442,308 - 52,454,083 (-)NCBINCBI36Build 36hg18NCBI36
Celera352,446,585 - 52,458,288 (-)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef352,529,926 - 52,541,701 (-)NCBIHuRef
CHM1_1352,419,717 - 52,431,420 (-)NCBICHM1_1
T2T-CHM13v2.0352,466,008 - 52,478,004 (-)NCBIT2T-CHM13v2.0
Sema3g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,939,830 - 30,952,309 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,939,817 - 30,952,309 (+)EnsemblGRCm39 Ensembl
GRCm381431,217,873 - 31,230,352 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,217,860 - 31,230,352 (+)EnsemblGRCm38mm10GRCm38
MGSCv371432,031,059 - 32,042,697 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,046,882 - 30,058,520 (+)NCBIMGSCv36mm8
Celera1427,476,482 - 27,488,116 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.09NCBI
Sema3g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,420,025 - 6,431,655 (+)NCBIGRCr8
mRatBN7.2166,413,589 - 6,425,221 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,413,589 - 6,425,221 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,425,837 - 6,437,406 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,570,735 - 7,582,302 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,432,899 - 6,444,592 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,303,582 - 7,315,214 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,303,578 - 7,315,390 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,231,864 - 7,243,496 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,651,366 - 6,662,999 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,651,400 - 6,661,751 (+)NCBI
Celera168,763,787 - 8,775,420 (-)NCBICelera
Cytogenetic Map16p16NCBI
Sema3g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,422,934 - 2,433,001 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,409,847 - 2,433,001 (-)NCBIChiLan1.0ChiLan1.0
SEMA3G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,428,569 - 52,440,209 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,433,341 - 52,444,982 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,375,215 - 52,387,115 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,603,867 - 53,615,739 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,603,867 - 53,615,739 (-)Ensemblpanpan1.1panPan2
SEMA3G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,322,531 - 37,334,333 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,322,565 - 37,332,818 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,304,004 - 37,315,800 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,672,570 - 37,684,360 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,672,563 - 37,683,348 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,036,521 - 37,048,318 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,445,180 - 37,456,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,729,778 - 37,745,527 (+)NCBIUU_Cfam_GSD_1.0
Sema3g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,133,608 - 170,146,054 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,271,904 - 3,284,735 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364733,272,213 - 3,284,601 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA3G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,574,200 - 34,585,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,574,014 - 34,585,686 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,787,753 - 37,799,424 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEMA3G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,798,635 - 13,813,779 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,798,366 - 13,810,183 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,089,645 - 153,101,373 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sema3g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,773,276 - 4,784,850 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248224,773,479 - 4,784,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in SEMA3G
343 total Variants

1 to 10 of 356 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 3p21.31-14.3(chr3:49461000-55314500)x1 copy number loss See cases [RCV000051511] Chr3:49461000..55314500 [GRCh38]
Chr3:49498433..55348528 [GRCh37]
Chr3:49473437..55323568 [NCBI36]
Chr3:3p21.31-14.3		 pathogenic
GRCh38/hg38 3p21.2-14.3(chr3:51394434-55064449)x1 copy number loss See cases [RCV000143631] Chr3:51394434..55064449 [GRCh38]
Chr3:51431865..55098476 [GRCh37]
Chr3:51406905..55073516 [NCBI36]
Chr3:3p21.2-14.3		 likely pathogenic
GRCh37/hg19 3p21.2-14.2(chr3:52086599-59689209)x1 copy number loss See cases [RCV000239886] Chr3:52086599..59689209 [GRCh37]
Chr3:3p21.2-14.2		 pathogenic
NM_020163.3(SEMA3G):c.1309C>T (p.His437Tyr) single nucleotide variant not specified [RCV004317838] Chr3:52439933 [GRCh38]
Chr3:52473949 [GRCh37]
Chr3:3p21.1		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_020163.3(SEMA3G):c.385A>C (p.Thr129Pro) single nucleotide variant not specified [RCV004321024] Chr3:52442259 [GRCh38]
Chr3:52476275 [GRCh37]
Chr3:3p21.1		 uncertain significance
NM_020163.3(SEMA3G):c.2054C>T (p.Pro685Leu) single nucleotide variant not specified [RCV004311488] Chr3:52435898 [GRCh38]
Chr3:52469914 [GRCh37]
Chr3:3p21.1		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_020163.3(SEMA3G):c.11C>T (p.Ser4Leu) single nucleotide variant SEMA3G-related disorder [RCV004747284]|not specified [RCV004317284] Chr3:52445017 [GRCh38]
Chr3:52479033 [GRCh37]
Chr3:3p21.1		 uncertain significance
NM_020163.3(SEMA3G):c.1606C>T (p.Arg536Trp) single nucleotide variant not specified [RCV004309062] Chr3:52438103 [GRCh38]
Chr3:52472119 [GRCh37]
Chr3:3p21.1		 uncertain significance
1 to 10 of 356 rows

Predicted Target Of
Summary Value
Count of predictions:2105
Count of miRNA genes:968
Interacting mature miRNAs:1206
Transcripts:ENST00000231721, ENST00000465657, ENST00000475739
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298487BFD1_HBody fluid distribution QTL 1 (human)3.94Body fluid distributionimpedance ratio33638071262380712Human
597124126GWAS1220200_Hblood protein measurement QTL GWAS1220200 (human)9e-20blood protein amount (VT:0005416)blood protein measurement (CMO:0000028)35243330852433309Human
1298489RA4_HRheumatoid arthritis QTL 4 (human)0.0283Joint/bone inflammationrheumatoid arthritis33638071262380712Human
597429558GWAS1525632_Hprotein measurement QTL GWAS1525632 (human)7e-12protein measurement35243792652437927Human
596961087GWAS1080606_Hmetabolic syndrome QTL GWAS1080606 (human)9e-11metabolic syndrome35243330852433309Human
1643509BW293_HBody Weight QTL 293 (human)1.42Body weightBMI33638071262380712Human
1331643COPD16_HChronic obstructive pulmonary disease QTL 16 (human)1.07Chronic airflow obstructionpost-BD FEV1 minus pre-BD FEV1/pre-BD FEV1 x 10034938065175380651Human
596961088GWAS1080607_Hmetabolic syndrome QTL GWAS1080607 (human)2e-14metabolic syndrome35244306452443065Human
597061283GWAS1157357_Hmetabolic syndrome QTL GWAS1157357 (human)9e-11metabolic syndrome35243330852433309Human
597524264GWAS1620338_Hsemaphorin-3G measurement QTL GWAS1620338 (human)4e-107semaphorin-3G measurement35244306452443065Human

1 to 10 of 15 rows
SHGC-58480  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37352,467,488 - 52,467,654UniSTSGRCh37
Build 36352,442,528 - 52,442,694RGDNCBI36
Celera352,446,805 - 52,446,971RGD
Cytogenetic Map3p21.1UniSTS
HuRef352,530,146 - 52,530,312UniSTS
TNG Radiation Hybrid Map332420.0UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2421 2788 2244 4942 1721 2309 6 623 1596 464 2251 6933 6124 47 3721 1 836 1719 1575 172 1



Ensembl Acc Id: ENST00000231721   ⟹   ENSP00000231721
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl352,433,035 - 52,445,103 (-)Ensembl
Ensembl Acc Id: ENST00000465657   ⟹   ENSP00000420291
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl352,440,390 - 52,444,969 (-)Ensembl
Ensembl Acc Id: ENST00000475739   ⟹   ENSP00000419181
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl352,441,865 - 52,445,085 (-)Ensembl
RefSeq Acc Id: NM_020163   ⟹   NP_064548
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38352,433,035 - 52,445,103 (-)NCBI
GRCh37352,467,268 - 52,479,112 (-)NCBI
Build 36352,442,308 - 52,454,083 (-)NCBI Archive
Celera352,446,585 - 52,458,288 (-)RGD
HuRef352,529,926 - 52,541,701 (-)ENTREZGENE
CHM1_1352,419,717 - 52,431,420 (-)NCBI
T2T-CHM13v2.0352,466,008 - 52,478,004 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024453642   ⟹   XP_024309410
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38352,433,035 - 52,445,103 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054347267   ⟹   XP_054203242
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0352,466,008 - 52,478,004 (-)NCBI
RefSeq Acc Id: NP_064548   ⟸   NM_020163
- Peptide Label: precursor
- UniProtKB: Q7L9D9 (UniProtKB/Swiss-Prot),   Q9H7Q3 (UniProtKB/Swiss-Prot),   Q9NS98 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_024309410   ⟸   XM_024453642
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSP00000420291   ⟸   ENST00000465657
Ensembl Acc Id: ENSP00000231721   ⟸   ENST00000231721
Ensembl Acc Id: ENSP00000419181   ⟸   ENST00000475739
Ig-like C2-type   Sema

Name Modeler Protein Id AA Range Protein Structure
AF-Q9NS98-F1-model_v2 AlphaFold Q9NS98 1-782 view protein structure

RGD ID:6864650
Promoter ID:EPDNEW_H5490
Type:multiple initiation site
Name:SEMA3G_1
Description:semaphorin 3G
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38352,445,103 - 52,445,163EPDNEW
RGD ID:6801653
Promoter ID:HG_KWN:45228
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_020163
Position:
Human AssemblyChrPosition (strand)Source
Build 36352,453,894 - 52,454,394 (-)MPROMDB


1 to 40 of 41 rows
Database
Acc Id
Source(s)
COSMIC SEMA3G COSMIC
Ensembl Genes ENSG00000010319 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000231721 ENTREZGENE
  ENST00000231721.7 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
  ligand-binding face of the semaphorins, domain 2 UniProtKB/Swiss-Prot
GTEx ENSG00000010319 GTEx
HGNC ID HGNC:30400 ENTREZGENE
Human Proteome Map SEMA3G Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Immunoglobulin UniProtKB/Swiss-Prot
  PSI UniProtKB/Swiss-Prot
  Semap_dom UniProtKB/Swiss-Prot
  Semap_dom_sf UniProtKB/Swiss-Prot
  Semaphorin UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
KEGG Report hsa:56920 UniProtKB/Swiss-Prot
NCBI Gene 56920 ENTREZGENE
OMIM 620997 OMIM
PANTHER PTHR11036 UniProtKB/Swiss-Prot
  SEMAPHORIN-3G UniProtKB/Swiss-Prot
Pfam PF00047 UniProtKB/Swiss-Prot
  Sema UniProtKB/Swiss-Prot
PharmGKB PA142670937 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  SEMA UniProtKB/Swiss-Prot
SMART PSI UniProtKB/Swiss-Prot
  Sema UniProtKB/Swiss-Prot
Superfamily-SCOP Plexin repeat UniProtKB/Swiss-Prot
  SSF101912 UniProtKB/Swiss-Prot
  SSF48726 UniProtKB/Swiss-Prot
UniProt C9JXB2_HUMAN UniProtKB/TrEMBL
  H7C5M7_HUMAN UniProtKB/TrEMBL
  Q7L9D9 ENTREZGENE
  Q9H7Q3 ENTREZGENE
  Q9NS98 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q7L9D9 UniProtKB/Swiss-Prot
1 to 40 of 41 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-19 SEMA3G  semaphorin 3G    sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G  Symbol and/or name change 5135510 APPROVED