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Gene: Sema3b (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B) Mus musculus
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Symbol: Sema3b
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
Description: This gene encodes a secreted protein that belongs to the class 3 semaphorin/collapsin family. Members of this family play a role in growth cone guidance during neurogenesis. The encoded protein inhibits axonal extension. This protein is thought to be an osteoblast protein that regulates bone mass and affects skeletal homeostasis. A similar gene in humans functions as a tumor suppressor gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AW208495; LUCA-1; SemA; sema A; sema5; Semaa; semaphorin-3B; semaphorin-A; semaV
Orthologs:
Homo sapiens (human) : SEMA3B (semaphorin 3B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sema3b (semaphorin 3B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema3b (semaphorin 3B)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA3B (semaphorin 3B)
Canis lupus familiaris (dog) : SEMA3B (semaphorin 3B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sema3b (semaphorin 3B)
Sus scrofa (pig) : SEMA3B (semaphorin 3B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389107,597,674 - 107,609,241 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379107,500,446 - 107,511,572 (-)NCBIGRCm37mm9NCBIm37
MGSCv369107,456,456 - 107,463,503 (-)NCBImm8
Celera9107,206,456 - 107,218,025 (-)NCBICelera
Cytogenetic Map9 F1NCBI
cM Map958.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sema3b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320779
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.