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Gene: Sema3b (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B) Mus musculus
Symbol: Sema3b
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
Description: This gene encodes a secreted protein that belongs to the class 3 semaphorin/collapsin family. Members of this family play a role in growth cone guidance during neurogenesis. The encoded protein inhibits axonal extension. This protein is thought to be an osteoblast protein that regulates bone mass and affects skeletal homeostasis. A similar gene in humans functions as a tumor suppressor gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AW208495; LUCA-1; SemA; sema A; sema5; Semaa; semaphorin-3B; semaphorin-A; semaV
Homo sapiens (human) : SEMA3B (semaphorin 3B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sema3b (semaphorin 3B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema3b (semaphorin 3B)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA3B (semaphorin 3B)
Canis lupus familiaris (dog) : SEMA3B (semaphorin 3B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sema3b (semaphorin 3B)
Sus scrofa (pig) : SEMA3B (semaphorin 3B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389107,597,674 - 107,609,241 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379107,500,446 - 107,511,572 (-)NCBIGRCm37mm9NCBIm37
MGSCv369107,456,456 - 107,463,503 (-)NCBImm8
Celera9107,206,456 - 107,218,025 (-)NCBICelera
Cytogenetic Map9 F1NCBI
cM Map958.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sema3b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320779
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.