SEMA3G (semaphorin 3G) - Rat Genome Database

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Gene: SEMA3G (semaphorin 3G) Canis lupus familiaris
Analyze
Symbol: SEMA3G
Name: semaphorin 3G
RGD ID: 12186279
Description: ENCODES a protein that exhibits chemorepellent activity (inferred); semaphorin receptor binding (inferred); signaling receptor binding (inferred); INVOLVED IN axon guidance (inferred); negative chemotaxis (inferred); negative regulation of axon extension (inferred); ASSOCIATED WITH congenital disorder of glycosylation In (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: semaphorin-3G
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,322,531 - 37,334,333 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,322,565 - 37,332,818 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,304,004 - 37,315,800 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,672,570 - 37,684,360 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,672,563 - 37,683,348 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,036,521 - 37,048,318 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,445,180 - 37,456,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,729,778 - 37,745,527 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SEMA3G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,322,531 - 37,334,333 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,322,565 - 37,332,818 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,304,004 - 37,315,800 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,672,570 - 37,684,360 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,672,563 - 37,683,348 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,036,521 - 37,048,318 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,445,180 - 37,456,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,729,778 - 37,745,527 (+)NCBIUU_Cfam_GSD_1.0
SEMA3G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,433,035 - 52,445,103 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,433,035 - 52,445,103 (-)EnsemblGRCh38hg38GRCh38
GRCh37352,467,051 - 52,479,119 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,442,308 - 52,454,083 (-)NCBINCBI36Build 36hg18NCBI36
Celera352,446,585 - 52,458,288 (-)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef352,529,926 - 52,541,701 (-)NCBIHuRef
CHM1_1352,419,717 - 52,431,420 (-)NCBICHM1_1
T2T-CHM13v2.0352,466,008 - 52,478,004 (-)NCBIT2T-CHM13v2.0
Sema3g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,939,830 - 30,952,309 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,939,817 - 30,952,309 (+)EnsemblGRCm39 Ensembl
GRCm381431,217,873 - 31,230,352 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1431,217,860 - 31,230,352 (+)EnsemblGRCm38mm10GRCm38
MGSCv371432,031,059 - 32,042,697 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,046,882 - 30,058,520 (+)NCBIMGSCv36mm8
Celera1427,476,482 - 27,488,116 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.09NCBI
Sema3g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,420,025 - 6,431,655 (+)NCBIGRCr8
mRatBN7.2166,413,589 - 6,425,221 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,413,589 - 6,425,221 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,425,837 - 6,437,406 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,570,735 - 7,582,302 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,432,899 - 6,444,592 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0167,303,582 - 7,315,214 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl167,303,578 - 7,315,390 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0167,231,864 - 7,243,496 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,651,366 - 6,662,999 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,651,400 - 6,661,751 (+)NCBI
Celera168,763,787 - 8,775,420 (-)NCBICelera
Cytogenetic Map16p16NCBI
Sema3g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,422,934 - 2,433,001 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,409,847 - 2,433,001 (-)NCBIChiLan1.0ChiLan1.0
SEMA3G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,428,569 - 52,440,209 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,433,341 - 52,444,982 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,375,215 - 52,387,115 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,603,867 - 53,615,739 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,603,867 - 53,615,739 (-)Ensemblpanpan1.1panPan2
Sema3g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,133,608 - 170,146,054 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,271,904 - 3,284,735 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364733,272,213 - 3,284,601 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA3G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,574,200 - 34,585,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,574,014 - 34,585,686 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,787,753 - 37,799,424 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEMA3G
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,798,635 - 13,813,779 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,798,366 - 13,810,183 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,089,645 - 153,101,373 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sema3g
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,773,276 - 4,784,850 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248224,773,479 - 4,784,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SEMA3G
63 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 4 5 6
Low 5 5 17 1 5 1 2 6 12 5
Below cutoff 5 5 5 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000015081   ⟹   ENSCAFP00000013954
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2037,322,565 - 37,332,818 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000080708   ⟹   ENSCAFP00000056361
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2037,322,565 - 37,332,818 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845053936   ⟹   ENSCAFP00845042381
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2037,672,563 - 37,683,348 (+)Ensembl
RefSeq Acc Id: XM_038427559   ⟹   XP_038283487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02037,672,570 - 37,684,360 (+)NCBI
RefSeq Acc Id: XM_038503267   ⟹   XP_038359195
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12037,036,521 - 37,048,318 (+)NCBI
RefSeq Acc Id: XM_038566243   ⟹   XP_038422171
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02037,729,778 - 37,745,527 (+)NCBI
RefSeq Acc Id: XM_038630405   ⟹   XP_038486333
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02037,445,180 - 37,456,976 (+)NCBI
RefSeq Acc Id: XM_541852   ⟹   XP_541852
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12037,322,531 - 37,334,333 (+)NCBI
Dog10K_Boxer_Tasha2037,304,004 - 37,315,800 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_541852   ⟸   XM_541852
- UniProtKB: A0A8C0JJQ8 (UniProtKB/TrEMBL),   A0A8C0TE37 (UniProtKB/TrEMBL),   A0A8P0NBL9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000013954   ⟸   ENSCAFT00000015081
RefSeq Acc Id: ENSCAFP00000056361   ⟸   ENSCAFT00000080708
RefSeq Acc Id: XP_038359195   ⟸   XM_038503267
RefSeq Acc Id: XP_038486333   ⟸   XM_038630405
RefSeq Acc Id: XP_038283487   ⟸   XM_038427559
- UniProtKB: A0A8I3S7L5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038422171   ⟸   XM_038566243
- UniProtKB: A0A8C0JJQ8 (UniProtKB/TrEMBL),   A0A8C0TE37 (UniProtKB/TrEMBL),   A0A8P0NBL9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845042381   ⟸   ENSCAFT00845053936
Protein Domains
Ig-like   Sema

Promoters
RGD ID:13686847
Promoter ID:EPDNEW_C4916
Type:single initiation site
Name:SEMA3G_1
Description:semaphorin 3G
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12037,322,540 - 37,322,600EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009481 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006847 UniProtKB/TrEMBL
  ENSCAFG00040021283 UniProtKB/TrEMBL
  ENSCAFG00845030395 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000015081.6 UniProtKB/TrEMBL
  ENSCAFT00030012605.1 UniProtKB/TrEMBL
  ENSCAFT00040039492.1 UniProtKB/TrEMBL
  ENSCAFT00845053936 ENTREZGENE
  ENSCAFT00845053936.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Semaphorin UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:484736 UniProtKB/TrEMBL
NCBI Gene SEMA3G ENTREZGENE
PANTHER PTHR11036 UniProtKB/TrEMBL
  SEMAPHORIN-3G UniProtKB/TrEMBL
Pfam PF00047 UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  SEMA UniProtKB/TrEMBL
SMART PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  SSF101912 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A8C0JJQ8 ENTREZGENE
  A0A8C0TE37 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S7L5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NBL9 ENTREZGENE
UniProt Secondary A0A8P0NBL9 UniProtKB/TrEMBL
VGNC ID VGNC:45993 ENTREZGENE