Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of SERPINB12 mRNA | CTD | PMID:28960355 | 17alpha-ethynylestradiol | multiple interactions | ISO | Serpinb12 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SERPINB12 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Serpinb12 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SERPINB12 mRNA | CTD | PMID:17942748 | 4,4'-sulfonyldiphenol | increases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | bisphenol S results in increased expression of SERPINB12 mRNA | CTD | PMID:30951980 | acrylamide | increases expression | ISO | Serpinb12 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of SERPINB12 mRNA | CTD | PMID:28959563 | benzo[a]pyrene | increases mutagenesis | EXP | | 6480464 | Benzo(a)pyrene results in increased mutagenesis of SERPINB12 gene | CTD | PMID:25435355 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of SERPINB12 promoter | CTD | PMID:27901495 | Benzo[k]fluoranthene | decreases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of SERPINB12 mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | ISO | Serpinb12 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SERPINB12 mRNA | CTD | PMID:25181051 and PMID:34947998 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SERPINB12 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SERPINB12 mRNA | CTD | PMID:35301059 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SERPINB12 gene] | CTD | PMID:28238834 | doxorubicin | decreases expression | ISO | Serpinb12 (Rattus norvegicus) | 6480464 | Doxorubicin results in decreased expression of SERPINB12 mRNA | CTD | PMID:32289291 | genistein | increases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | Genistein results in increased expression of SERPINB12 mRNA | CTD | PMID:22553218 | genistein | decreases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | Genistein results in decreased expression of SERPINB12 mRNA | CTD | PMID:32186404 | lipopolysaccharide | multiple interactions | EXP | | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of SERPINB12 mRNA | CTD | PMID:35811015 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SERPINB12 mRNA | CTD | PMID:26690555 | phenethyl isothiocyanate | increases expression | ISO | Serpinb12 (Rattus norvegicus) | 6480464 | phenethyl isothiocyanate results in increased expression of SERPINB12 mRNA | CTD | PMID:17616710 | pirinixic acid | multiple interactions | ISO | Serpinb12 (Mus musculus) | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of SERPINB12 mRNA | CTD | PMID:20813756 | pirinixic acid | increases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SERPINB12 mRNA | CTD | PMID:20813756 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SERPINB12 mRNA | CTD | PMID:23557933 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | EXP | | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of SERPINB12 mRNA | CTD | PMID:35811015 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of SERPINB12 mRNA | CTD | PMID:25879800 | sodium arsenite | increases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of SERPINB12 mRNA | CTD | PMID:37682722 | sodium fluoride | decreases expression | ISO | Serpinb12 (Rattus norvegicus) | 6480464 | Sodium Fluoride results in decreased expression of SERPINB12 mRNA | CTD | PMID:27257137 | succimer | multiple interactions | ISO | Serpinb12 (Mus musculus) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of SERPINB12 mRNA | CTD | PMID:26378955 | titanium dioxide | increases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SERPINB12 mRNA | CTD | PMID:23409001 | trichloroethene | increases expression | ISO | Serpinb12 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of SERPINB12 mRNA | CTD | PMID:33387578 | trovafloxacin | decreases expression | ISO | Serpinb12 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of SERPINB12 mRNA | CTD | PMID:35537566 | |