ZNF706 (zinc finger protein 706) - Rat Genome Database

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Gene: ZNF706 (zinc finger protein 706) Homo sapiens
Analyze
Symbol: ZNF706
Name: zinc finger protein 706
RGD ID: 1602889
HGNC Page HGNC
Description: Predicted to have metal ion binding activity. Predicted to be involved in negative regulation of stem cell population maintenance and negative regulation of transcription, DNA-templated. Predicted to localize to cytoplasm and nucleus; INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 3-isobutyl-1-methyl-7H-xanthine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HSPC038; PNAS-106; PNAS-113
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC724084  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8101,177,878 - 101,206,193 (-)EnsemblGRCh38hg38GRCh38
GRCh388101,197,052 - 101,206,470 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378102,209,280 - 102,218,450 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368102,278,442 - 102,287,166 (-)NCBINCBI36hg18NCBI36
Celera898,394,217 - 98,402,912 (-)NCBI
Cytogenetic Map8q22.3NCBI
HuRef897,407,169 - 97,416,179 (-)NCBIHuRef
CHM1_18102,249,557 - 102,258,585 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISS)
nucleus  (ISS)

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11042152   PMID:12477932   PMID:14702039   PMID:15489334   PMID:16344560   PMID:21107309   PMID:21832049   PMID:21917931   PMID:22939629   PMID:27609421   PMID:28514442   PMID:31815296  


Genomics

Comparative Map Data
ZNF706
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8101,177,878 - 101,206,193 (-)EnsemblGRCh38hg38GRCh38
GRCh388101,197,052 - 101,206,470 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378102,209,280 - 102,218,450 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368102,278,442 - 102,287,166 (-)NCBINCBI36hg18NCBI36
Celera898,394,217 - 98,402,912 (-)NCBI
Cytogenetic Map8q22.3NCBI
HuRef897,407,169 - 97,416,179 (-)NCBIHuRef
CHM1_18102,249,557 - 102,258,585 (-)NCBICHM1_1
Zfp706
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391536,997,271 - 37,007,646 (-)NCBIGRCm39mm39
GRCm39 Ensembl1536,997,271 - 37,008,017 (-)Ensembl
GRCm381536,997,027 - 37,007,402 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1536,997,027 - 37,007,773 (-)EnsemblGRCm38mm10GRCm38
MGSCv371536,926,782 - 36,937,157 (-)NCBIGRCm37mm9NCBIm37
MGSCv361536,941,616 - 36,951,991 (-)NCBImm8
Celera1537,596,719 - 37,635,153 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
Zfp706
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2768,167,499 - 68,174,042 (-)NCBI
Rnor_6.0 Ensembl775,801,735 - 75,809,836 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0775,803,310 - 75,809,853 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0775,945,357 - 75,951,900 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4772,511,133 - 72,517,676 (-)NCBIRGSC3.4rn4RGSC3.4
Celera765,244,549 - 65,251,092 (-)NCBICelera
Cytogenetic Map7q22NCBI
Znf706
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541716,263,846 - 16,268,527 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541716,263,846 - 16,268,526 (-)NCBIChiLan1.0ChiLan1.0
ZNF706
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18100,004,219 - 100,012,125 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8100,004,227 - 100,012,127 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0897,835,750 - 97,845,132 (-)NCBIMhudiblu_PPA_v0panPan3
ZNF706
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1132,967,884 - 2,978,040 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl132,969,983 - 2,976,279 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha132,967,797 - 2,978,050 (-)NCBI
ROS_Cfam_1.0133,125,325 - 3,135,591 (-)NCBI
UMICH_Zoey_3.1132,968,884 - 2,979,130 (-)NCBI
UNSW_CanFamBas_1.0133,081,781 - 3,091,993 (-)NCBI
UU_Cfam_GSD_1.0133,098,385 - 3,108,693 (-)NCBI
Znf706
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530334,813,862 - 34,827,393 (+)NCBI
SpeTri2.0NW_00493647042,245,657 - 42,253,492 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF706
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1435,768,087 - 35,777,048 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2438,717,300 - 38,724,418 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF706
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1896,062,498 - 96,072,104 (-)NCBI
ChlSab1.1 Ensembl896,064,379 - 96,067,511 (-)Ensembl
Znf706
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247637,934,894 - 7,942,900 (-)NCBI

Position Markers
SHGC-76423  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371224,363,046 - 224,363,285UniSTSGRCh37
Build 361222,429,669 - 222,429,908RGDNCBI36
Celera1197,553,979 - 197,554,218RGD
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map1q42.11UniSTS
HuRef1194,883,773 - 194,884,012UniSTS
TNG Radiation Hybrid Map1111643.0UniSTS
GeneMap99-GB4 RH Map1715.51UniSTS
D8S1421E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378102,210,915 - 102,211,061UniSTSGRCh37
Build 368102,280,091 - 102,280,237RGDNCBI36
Celera898,395,866 - 98,396,012RGD
Cytogenetic Map8q22.3UniSTS
HuRef897,408,818 - 97,408,964UniSTS
D8S1393E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378102,209,305 - 102,209,459UniSTSGRCh37
Build 368102,278,481 - 102,278,635RGDNCBI36
Celera898,394,256 - 98,394,410RGD
Cytogenetic Map8q22.3UniSTS
HuRef897,407,208 - 97,407,362UniSTS
GeneMap99-GB4 RH Map8439.42UniSTS
9STS01  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378102,211,324 - 102,211,460UniSTSGRCh37
GRCh371224,363,021 - 224,363,158UniSTSGRCh37
Celera1197,553,954 - 197,554,091UniSTS
Celera898,396,275 - 98,396,411UniSTS
HuRef1194,883,748 - 194,883,885UniSTS
HuRef897,409,227 - 97,409,363UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2656
Count of miRNA genes:983
Interacting mature miRNAs:1165
Transcripts:ENST00000311212, ENST00000517844, ENST00000518071, ENST00000518336, ENST00000519103, ENST00000519744, ENST00000519882, ENST00000519916, ENST00000520347, ENST00000520454, ENST00000520498, ENST00000520984, ENST00000521272, ENST00000523146, ENST00000523922
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2407 1612 1436 355 1231 197 4077 1510 3382 325 1437 1601 171 1200 2510 3
Low 26 1371 287 268 716 267 279 683 328 93 12 7 4 278 1 1
Below cutoff 2 4 1 1 1 1 13 4 3 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001042510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001267708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001267709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_016096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024447172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024447173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF125099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF275802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF275809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP003469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV721205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG704587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI669563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI755311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB231109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB549532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000311212   ⟹   ENSP00000311768
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,197,052 - 101,205,673 (-)Ensembl
RefSeq Acc Id: ENST00000517844   ⟹   ENSP00000428227
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,198,933 - 101,204,701 (-)Ensembl
RefSeq Acc Id: ENST00000518071   ⟹   ENSP00000431059
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,177,997 - 101,200,093 (-)Ensembl
RefSeq Acc Id: ENST00000518336   ⟹   ENSP00000428696
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,199,195 - 101,206,064 (-)Ensembl
RefSeq Acc Id: ENST00000519103   ⟹   ENSP00000427803
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,198,937 - 101,201,657 (-)Ensembl
RefSeq Acc Id: ENST00000519744   ⟹   ENSP00000429645
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,198,726 - 101,205,568 (-)Ensembl
RefSeq Acc Id: ENST00000519882   ⟹   ENSP00000428985
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,198,939 - 101,205,732 (-)Ensembl
RefSeq Acc Id: ENST00000519916
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,201,220 - 101,205,507 (-)Ensembl
RefSeq Acc Id: ENST00000520347   ⟹   ENSP00000430823
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,198,938 - 101,205,287 (-)Ensembl
RefSeq Acc Id: ENST00000520454   ⟹   ENSP00000430090
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,201,716 - 101,206,193 (-)Ensembl
RefSeq Acc Id: ENST00000520498
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,198,924 - 101,200,288 (-)Ensembl
RefSeq Acc Id: ENST00000520984   ⟹   ENSP00000427761
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,177,878 - 101,205,461 (-)Ensembl
RefSeq Acc Id: ENST00000521272   ⟹   ENSP00000430165
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,199,160 - 101,205,682 (-)Ensembl
RefSeq Acc Id: ENST00000523146   ⟹   ENSP00000430845
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,200,036 - 101,205,474 (-)Ensembl
RefSeq Acc Id: ENST00000523922   ⟹   ENSP00000429260
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8101,201,615 - 101,205,329 (-)Ensembl
RefSeq Acc Id: NM_001042510   ⟹   NP_001035975
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388101,197,052 - 101,205,673 (-)NCBI
GRCh378102,209,266 - 102,218,292 (-)NCBI
Build 368102,278,442 - 102,287,136 (-)NCBI Archive
Celera898,394,217 - 98,402,912 (-)RGD
HuRef897,407,169 - 97,416,179 (-)NCBI
CHM1_18102,249,557 - 102,258,253 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001267708   ⟹   NP_001254637
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388101,197,052 - 101,205,673 (-)NCBI
GRCh378102,209,266 - 102,218,292 (-)NCBI
HuRef897,407,169 - 97,416,179 (-)NCBI
CHM1_18102,249,557 - 102,258,253 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001267709   ⟹   NP_001254638
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388101,197,052 - 101,206,222 (-)NCBI
GRCh378102,209,266 - 102,218,292 (-)NCBI
HuRef897,407,169 - 97,416,179 (-)NCBI
CHM1_18102,249,557 - 102,258,585 (-)NCBI
Sequence:
RefSeq Acc Id: NM_016096   ⟹   NP_057180
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388101,197,052 - 101,205,673 (-)NCBI
GRCh378102,209,266 - 102,218,292 (-)NCBI
Build 368102,278,442 - 102,287,136 (-)NCBI Archive
Celera898,394,217 - 98,402,912 (-)RGD
HuRef897,407,169 - 97,416,179 (-)NCBI
CHM1_18102,249,557 - 102,258,253 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024447172   ⟹   XP_024302940
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388101,198,437 - 101,206,470 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024447173   ⟹   XP_024302941
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388101,197,052 - 101,205,648 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001035975   ⟸   NM_001042510
- UniProtKB: Q9Y5V0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_057180   ⟸   NM_016096
- UniProtKB: Q9Y5V0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001254638   ⟸   NM_001267709
- UniProtKB: Q9Y5V0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001254637   ⟸   NM_001267708
- UniProtKB: Q9Y5V0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_024302941   ⟸   XM_024447173
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024302940   ⟸   XM_024447172
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000428227   ⟸   ENST00000517844
RefSeq Acc Id: ENSP00000431059   ⟸   ENST00000518071
RefSeq Acc Id: ENSP00000428696   ⟸   ENST00000518336
RefSeq Acc Id: ENSP00000427803   ⟸   ENST00000519103
RefSeq Acc Id: ENSP00000428985   ⟸   ENST00000519882
RefSeq Acc Id: ENSP00000429645   ⟸   ENST00000519744
RefSeq Acc Id: ENSP00000427761   ⟸   ENST00000520984
RefSeq Acc Id: ENSP00000430090   ⟸   ENST00000520454
RefSeq Acc Id: ENSP00000430823   ⟸   ENST00000520347
RefSeq Acc Id: ENSP00000430165   ⟸   ENST00000521272
RefSeq Acc Id: ENSP00000311768   ⟸   ENST00000311212
RefSeq Acc Id: ENSP00000429260   ⟸   ENST00000523922
RefSeq Acc Id: ENSP00000430845   ⟸   ENST00000523146
Protein Domains
4F5

Promoters
RGD ID:7213907
Promoter ID:EPDNEW_H12699
Type:initiation region
Name:ZNF706_2
Description:zinc finger protein 706
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12700  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388101,205,507 - 101,205,567EPDNEW
RGD ID:7213909
Promoter ID:EPDNEW_H12700
Type:initiation region
Name:ZNF706_1
Description:zinc finger protein 706
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12699  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388101,205,648 - 101,205,708EPDNEW
RGD ID:6815638
Promoter ID:HG_MRA:15981
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:AK027802
Position:
Human AssemblyChrPosition (strand)Source
Build 368102,285,476 - 102,286,182 (-)MPROMDB
RGD ID:6807190
Promoter ID:HG_KWN:61822
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001042510,   NM_016096
Position:
Human AssemblyChrPosition (strand)Source
Build 368102,287,066 - 102,287,566 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:95606052-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|See cases [RCV000053677] Chr8:95606052..145054775 [GRCh38]
Chr8:96618280..146280161 [GRCh37]
Chr8:96687456..146250965 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q21.3-24.23(chr8:86300584-137022587)x3 copy number gain See cases [RCV000135621] Chr8:86300584..137022587 [GRCh38]
Chr8:87312813..138034830 [GRCh37]
Chr8:87381929..138104012 [NCBI36]
Chr8:8q21.3-24.23
pathogenic|likely pathogenic
GRCh38/hg38 8q22.3-23.1(chr8:101199826-105802098)x1 copy number loss See cases [RCV000136812] Chr8:101199826..105802098 [GRCh38]
Chr8:102212054..106814326 [GRCh37]
Chr8:102281230..106883502 [NCBI36]
Chr8:8q22.3-23.1
pathogenic
GRCh38/hg38 8q22.2-22.3(chr8:99580206-101547228)x1 copy number loss See cases [RCV000137322] Chr8:99580206..101547228 [GRCh38]
Chr8:100592434..102559456 [GRCh37]
Chr8:100661610..102628632 [NCBI36]
Chr8:8q22.2-22.3
likely pathogenic
GRCh38/hg38 8q22.3-23.1(chr8:101171263-109127664)x1 copy number loss See cases [RCV000138134] Chr8:101171263..109127664 [GRCh38]
Chr8:102183491..110139893 [GRCh37]
Chr8:102252667..110209069 [NCBI36]
Chr8:8q22.3-23.1
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:97382873-145070385)x3 copy number gain See cases [RCV000140447] Chr8:97382873..145070385 [GRCh38]
Chr8:98395101..146295771 [GRCh37]
Chr8:98464277..146266575 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.2-23.1(chr8:100179408-106524667)x1 copy number loss See cases [RCV000141697] Chr8:100179408..106524667 [GRCh38]
Chr8:101191636..107536895 [GRCh37]
Chr8:101260812..107606071 [NCBI36]
Chr8:8q22.2-23.1
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:100867343-145070385)x3 copy number gain See cases [RCV000141694] Chr8:100867343..145070385 [GRCh38]
Chr8:101879571..146295771 [GRCh37]
Chr8:101948747..146266575 [NCBI36]
Chr8:8q22.3-24.3
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8p12-q24.3(chr8:31936551-146295771)x3 copy number gain not provided [RCV000848192] Chr8:31936551..146295771 [GRCh37]
Chr8:8p12-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158991-146280828)x3 copy number gain See cases [RCV000447507] Chr8:158991..146280828 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q22.1-24.3(chr8:98432250-146222672)x4 copy number gain See cases [RCV000448954] Chr8:98432250..146222672 [GRCh37]
Chr8:8q22.1-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771) copy number gain See cases [RCV000510234] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.3-24.3(chr8:93047482-141355635)x3 copy number gain See cases [RCV000511761] Chr8:93047482..141355635 [GRCh37]
Chr8:8q21.3-24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841154-146295771)x3 copy number gain See cases [RCV000511002] Chr8:86841154..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771)x3 copy number gain See cases [RCV000511095] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841228-142689874)x3 copy number gain See cases [RCV000510854] Chr8:86841228..142689874 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8p23.1-q24.3(chr8:12490999-146295771)x3 copy number gain See cases [RCV000512169] Chr8:12490999..146295771 [GRCh37]
Chr8:8p23.1-q24.3
pathogenic
GRCh37/hg19 8q21.2-23.3(chr8:86841154-116518125)x3 copy number gain not provided [RCV000683045] Chr8:86841154..116518125 [GRCh37]
Chr8:8q21.2-23.3
pathogenic
GRCh37/hg19 8q22.2-22.3(chr8:100551211-103676738)x1 copy number loss not provided [RCV000683023] Chr8:100551211..103676738 [GRCh37]
Chr8:8q22.2-22.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:164984-146293414)x3 copy number gain not provided [RCV000747254] Chr8:164984..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:10213-146293414)x3 copy number gain not provided [RCV000747248] Chr8:10213..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not provided [RCV000848478] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:24992 AgrOrtholog
COSMIC ZNF706 COSMIC
Ensembl Genes ENSG00000120963 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000311768 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000427761 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000427803 UniProtKB/TrEMBL
  ENSP00000428227 UniProtKB/Swiss-Prot
  ENSP00000428696 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000428985 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000429260 UniProtKB/TrEMBL
  ENSP00000429645 UniProtKB/TrEMBL
  ENSP00000430090 UniProtKB/TrEMBL
  ENSP00000430165 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000430823 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000430845 UniProtKB/TrEMBL
  ENSP00000431059 UniProtKB/TrEMBL
Ensembl Transcript ENST00000311212 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000517844 UniProtKB/Swiss-Prot
  ENST00000518071 UniProtKB/TrEMBL
  ENST00000518336 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000519103 UniProtKB/TrEMBL
  ENST00000519744 UniProtKB/TrEMBL
  ENST00000519882 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000520347 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000520454 UniProtKB/TrEMBL
  ENST00000520984 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000521272 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000523146 UniProtKB/TrEMBL
  ENST00000523922 UniProtKB/TrEMBL
Gene3D-CATH 4.10.1050.10 UniProtKB/Swiss-Prot
GTEx ENSG00000120963 GTEx
HGNC ID HGNC:24992 ENTREZGENE
Human Proteome Map ZNF706 Human Proteome Map
InterPro Uncharacterised_SERF_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZNF706/At2g23090_sf UniProtKB/Swiss-Prot
KEGG Report hsa:51123 UniProtKB/Swiss-Prot
NCBI Gene 51123 ENTREZGENE
Pfam 4F5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA142670505 PharmGKB, RGD
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
UniProt A0A1D5RMS7_HUMAN UniProtKB/TrEMBL
  E5RHR6_HUMAN UniProtKB/TrEMBL
  E5RHV4_HUMAN UniProtKB/TrEMBL
  E5RIY7_HUMAN UniProtKB/TrEMBL
  H0YAP1_HUMAN UniProtKB/TrEMBL
  H0YC70_HUMAN UniProtKB/TrEMBL
  Q9Y5V0 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A8K362 UniProtKB/Swiss-Prot