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Gene: PARD3 (par-3 family cell polarity regulator) Homo sapiens
Symbol: PARD3
Name: par-3 family cell polarity regulator
Description: Predicted to have phosphatidylinositol-3,4,5-trisphosphate binding activity; phosphatidylinositol-3-phosphate binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including bicellular tight junction assembly; establishment of centrosome localization; and negative regulation of peptidyl-threonine phosphorylation. Localizes to the bicellular tight junction and cytoplasmic ribonucleoprotein granule.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ASIP; atypical PKC isotype-specific interacting protein; atypical PKC isotype-specific-interacting protein; Baz; bazooka; CTCL tumor antigen se2-5; FLJ21015; par-3 family cell polarity regulator alpha; par-3 partitioning defective 3 homolog; PAR3; PAR3-alpha; PAR3alpha; PARD-3; PARD3A; partitioning defective 3 homolog; PPP1R118; SE2-5L16; SE2-5LT1; SE2-5T2; three-pdz containing protein similar to c. elegans par3 (partitioning defect)
Mus musculus (house mouse) : Pard3 (par-3 family cell polarity regulator)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pard3 (par-3 family cell polarity regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pard3 (par-3 family cell polarity regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : PARD3 (par-3 family cell polarity regulator)
Canis lupus familiaris (dog) : PARD3 (par-3 family cell polarity regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pard3 (par-3 family cell polarity regulator)
Sus scrofa (pig) : PARD3 (par-3 family cell polarity regulator)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381034,109,560 - 34,815,325 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371034,398,488 - 35,104,253 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361034,440,103 - 35,143,929 (-)NCBINCBI36hg18NCBI36
Build 341034,440,102 - 35,143,929NCBI
Celera1034,163,865 - 34,869,585 (-)NCBI
Cytogenetic Map10p11.22-p11.21NCBI
HuRef1034,117,758 - 34,726,488 (-)NCBIHuRef
CHM1_11034,399,927 - 35,105,524 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PARD3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731593
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.