Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of innate immune response
go back to main search page
Accession:GO:0045089 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
Synonyms:exact_synonym: up regulation of innate immune response;   upregulation of innate immune response
 narrow_synonym: stimulation of innate immune response


show annotations for term's descendants           Sort by:
positive regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868 		JBrowse link
G AKIRIN2 akirin 2 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:87,674,860...87,702,233
Ensembl chr 6:87,674,860...87,702,233 		JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17187069) Ensembl
MGI		 PMID:17187069 GO_REF:0000107 NCBI chr 9:136,363,956...136,373,669
Ensembl chr 9:136,363,956...136,373,681 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 involved_in TAS (PMID:21148810) BHF-UCL PMID:21148810 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CD1D CD1d molecule involved_in TAS (PMID:14500461) UniProt PMID:14500461 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A involved_in IDA (PMID:38016475) UniProt PMID:38016475 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G DHX9 DExH-box helicase 9 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:182,839,347...182,887,982
Ensembl chr 1:182,839,347...182,887,982 		JBrowse link
G EREG epiregulin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G FADD Fas associated via death domain involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FPR2 formyl peptide receptor 2 involved_in IDA (PMID:25505240) ARUK-UCL PMID:25505240 NCBI chr19:51,761,180...51,770,531
Ensembl chr19:51,752,026...51,770,531 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:19890330) UniProt PMID:19890330 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMGB2 high mobility group box 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432 		JBrowse link
G IFI35 interferon induced protein 35 involved_in IDA
IEA		 (PMID:29038465) UniProt
Ensembl		 PMID:29038465 GO_REF:0000107 NCBI chr17:43,006,784...43,014,456
Ensembl chr17:43,006,740...43,014,456 		JBrowse link
G IFNB1 interferon beta 1 involved_in NAS (PMID:11987821) UniProt PMID:11987821 NCBI chr 9:21,077,104...21,077,942
Ensembl chr 9:21,077,104...21,077,942 		JBrowse link
G IFNK interferon kappa involved_in TAS (PMID:11514542) UniProt PMID:11514542 NCBI chr 9:27,524,290...27,526,498
Ensembl chr 9:27,524,290...27,526,498 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IDA (PMID:32817552) UniProt PMID:32817552 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:20937702) UniProt PMID:20937702 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G NMI N-myc and STAT interactor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15692051) Ensembl
MGI		 PMID:15692051 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PLSCR1 phospholipid scramblase 1 involved_in IMP (PMID:15308695) UniProt PMID:15308695 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856 		JBrowse link
G POLR3B RNA polymerase III subunit B involved_in IMP (PMID:19609254) UniProt PMID:19609254 NCBI chr12:106,357,748...106,510,198
Ensembl chr12:106,357,748...106,510,198 		JBrowse link
G POLR3C RNA polymerase III subunit C involved_in IMP (PMID:19609254) UniProt PMID:19609254 NCBI chr 1:145,824,200...145,844,402
Ensembl chr 1:145,824,053...145,844,402 		JBrowse link
G POLR3D RNA polymerase III subunit D involved_in IDA (PMID:19631370) UniProt PMID:19631370 NCBI chr 8:22,245,133...22,254,601
Ensembl chr 8:22,245,133...22,254,601 		JBrowse link
G POLR3F RNA polymerase III subunit F involved_in IMP (PMID:19631370) UniProt PMID:19631370 NCBI chr20:18,467,390...18,484,646
Ensembl chr20:18,466,878...18,484,648 		JBrowse link
G POLR3G RNA polymerase III subunit G involved_in IMP (PMID:19609254), (PMID:19631370) UniProt PMID:19609254 PMID:19631370 NCBI chr 5:90,473,929...90,514,557
Ensembl chr 5:90,471,748...90,514,557 		JBrowse link
G RIOK3 RIO kinase 3 involved_in IMP (PMID:24807708) UniProt PMID:24807708 NCBI chr18:23,453,287...23,483,140
Ensembl chr18:23,453,287...23,486,603 		JBrowse link
G RNF185 ring finger protein 185 involved_in IDA (PMID:28273161) UniProt PMID:28273161 NCBI chr22:31,160,182...31,207,019
Ensembl chr22:31,160,182...31,207,019 		JBrowse link
G SH2D1B SH2 domain containing 1B involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:162,395,268...162,412,136
Ensembl chr 1:162,395,268...162,412,138 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IDA (PMID:32433612) UniProt PMID:32433612 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in ISO (PMID:21531336) UniProt PMID:21531336 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IDA (PMID:32433612) UniProt PMID:32433612 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISO (PMID:16301656) BHF-UCL PMID:16301656 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR8 toll like receptor 8 involved_in IDA (PMID:16123302) UniProt PMID:16123302 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TRIM56 tripartite motif containing 56 involved_in IDA (PMID:29426904) UniProt PMID:29426904 NCBI chr 7:101,085,481...101,097,967
Ensembl chr 7:101,085,481...101,097,967 		JBrowse link
G ZDHHC4 zinc finger DHHC-type palmitoyltransferase 4 involved_in IDA (PMID:35606353) UniProt PMID:35606353 NCBI chr 7:6,577,454...6,589,374
Ensembl chr 7:6,577,434...6,589,374 		JBrowse link
activation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC097637.1 novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein involved_in IEA UniProt GO_REF:0000117 Ensembl chr 3:52,221,081...52,231,190 JBrowse link
G AIM2 absent in melanoma 2 involved_in IEA
IBA
IDA		 (PMID:19158675), (PMID:19158676), (PMID:19158679) Ensembl
GO_Central
UniProt
InterPro		 PMID:19158675 PMID:19158676 PMID:19158679 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:159,055,051...159,147,132
Ensembl chr 1:159,056,129...159,187,843 		JBrowse link
G CARD8 caspase recruitment domain family member 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:48,203,148...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
G CASP6 caspase 6 involved_in IDA (PMID:32298652) UniProt PMID:32298652 NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IEA
IBA
IDA
IMP		 (PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:29426904), (PMID:30007416), (PMID:32817552), (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35438208) Ensembl
GO_Central
UniProt		 PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More... GO_REF:0000033 GO_REF:0000107 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G GBP1 guanylate binding protein 1 involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360 		JBrowse link
G GBP2 guanylate binding protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GBP4 guanylate binding protein 4 involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 1:89,181,144...89,198,942
Ensembl chr 1:89,181,144...89,198,942 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
G GBP7 guanylate binding protein 7 involved_in ISO (PMID:24739961) UniProt PMID:24739961 NCBI chr 1:89,131,742...89,176,003
Ensembl chr 1:89,131,742...89,176,009 		JBrowse link
G HEXIM1 HEXIM P-TEFb complex subunit 1 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr17:45,148,475...45,152,099
Ensembl chr17:45,148,475...45,152,099 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IDA (PMID:24971542) UniProt PMID:24971542 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 involved_in IDA (PMID:20628368) UniProt PMID:20628368 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in IDA
IBA
IEA		 (PMID:21575908) UniProt
GO_Central
InterPro		 PMID:21575908 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G MATR3 matrin 3 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr 5:139,274,101...139,331,677
Ensembl chr 5:139,273,752...139,331,671
Ensembl chr 5:139,273,752...139,331,671 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IMP
IDA		 (PMID:18818105)
(PMID:20628368)		 BHF-UCL
UniProt		 PMID:18818105 PMID:20628368 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MNDA myeloid cell nuclear differentiation antigen involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:158,831,351...158,849,502
Ensembl chr 1:158,831,351...158,849,506 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:32,224,449...32,265,743
Ensembl chr 2:32,224,453...32,265,732 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
G NLRP10 NLR family pyrin domain containing 10 involved_in IMP (PMID:22672233) UniProt PMID:22672233 NCBI chr11:7,957,537...7,965,447
Ensembl chr11:7,957,537...7,965,447 		JBrowse link
G NONO non-POU domain containing octamer binding involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr  X:71,283,635...71,301,168
Ensembl chr  X:71,254,814...71,301,522 		JBrowse link
G PQBP1 polyglutamine binding protein 1 involved_in IDA (PMID:26046437) UniProt PMID:26046437 NCBI chr  X:48,897,930...48,903,143
Ensembl chr  X:48,890,197...48,903,402 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G PSPC1 paraspeckle component 1 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr13:19,671,205...19,782,945
Ensembl chr13:19,674,752...19,783,019 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IDA
IBA
IEA		 (PMID:21575908) UniProt
GO_Central
Ensembl		 PMID:21575908 GO_REF:0000033 GO_REF:0000107 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:158,931,552...158,990,870
Ensembl chr 1:158,930,796...158,977,059 		JBrowse link
G RBM14 RNA binding motif protein 14 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr11:66,616,630...66,629,934
Ensembl chr11:66,616,626...66,629,934 		JBrowse link
G RBM14-RBM4 RBM14-RBM4 readthrough involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr11:66,616,630...66,646,468
Ensembl chr11:66,616,626...66,646,469 		JBrowse link
G SFPQ splicing factor proline and glutamine rich involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr 1:35,176,380...35,193,145
Ensembl chr 1:35,176,378...35,193,446 		JBrowse link
G SIN3A SIN3 transcription regulator family member A involved_in IMP (PMID:22783022) BHF-UCL PMID:22783022 NCBI chr15:75,369,379...75,455,815
Ensembl chr15:75,369,379...75,455,842 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA
IBA
IDA
IMP		 (PMID:23910378)
(PMID:18818105)		 Ensembl
GO_Central
ComplexPortal
InterPro
BHF-UCL		 PMID:18818105 PMID:23910378 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO
IDA		 (PMID:15661922)
(PMID:25636800)		 Ensembl
GO_Central
MGI
UniProt		 PMID:15661922 PMID:25636800 GO_REF:0000033 GO_REF:0000107 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15661922) Ensembl
MGI		 PMID:15661922 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TOMM70 translocase of outer mitochondrial membrane 70 involved_in IDA (PMID:20628368) UniProt PMID:20628368 NCBI chr 3:100,363,431...100,401,089
Ensembl chr 3:100,363,431...100,401,089 		JBrowse link
G TRIM5 tripartite motif containing 5 involved_in IDA (PMID:21512573) UniProt PMID:21512573 NCBI chr11:5,588,635...5,685,074
Ensembl chr11:5,663,195...5,938,619 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 involved_in IDA (PMID:28712728) UniProt PMID:28712728 NCBI chr22:41,621,295...41,664,041
Ensembl chr22:41,621,163...41,664,048 		JBrowse link
G ZBP1 Z-DNA binding protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr20:57,603,852...57,620,426
Ensembl chr20:57,603,846...57,620,576 		JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in IEA
IBA
IDA		 (PMID:30135424), (PMID:30193849) Ensembl
GO_Central
InterPro
UniProt		 PMID:30135424 PMID:30193849 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr20:297,570...300,321
Ensembl chr20:297,570...300,321 		JBrowse link
G ZNFX1 zinc finger NFX1-type containing 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:49,245,900...49,278,057
Ensembl chr20:49,237,946...49,278,426 		JBrowse link
CARD8 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD8 caspase recruitment domain family member 8 involved_in IDA (PMID:31525884), (PMID:33053349), (PMID:33420028), (PMID:33420033) UniProt PMID:31525884 PMID:33053349 PMID:33420028 PMID:33420033 NCBI chr19:48,203,148...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IDA (PMID:15294986) AgBase PMID:15294986 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CLEC7A C-type lectin domain containing 7A acts_upstream_of_or_within
involved_in		 ISO
IDA		 (PMID:12719478)
(PMID:19358895)		 MGI
ARUK-UCL		 PMID:12719478 PMID:19358895 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G COLEC10 collectin subfamily member 10 involved_in NAS (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 8:118,952,263...119,108,455
Ensembl chr 8:118,995,452...119,108,455 		JBrowse link
G COLEC11 collectin subfamily member 11 involved_in NAS (PMID:24174618) ComplexPortal PMID:24174618 NCBI chr 2:3,595,112...3,644,644
Ensembl chr 2:3,594,832...3,644,644 		JBrowse link
G FCN1 ficolin 1 involved_in IMP
NAS		 (PMID:21037097) UniProt
ComplexPortal		 PMID:21037097 NCBI chr 9:134,903,232...134,917,912
Ensembl chr 9:134,903,232...134,917,912 		JBrowse link
G FCN2 ficolin 2 involved_in NAS (PMID:17215869) ComplexPortal PMID:17215869 NCBI chr 9:134,864,144...134,887,523
Ensembl chr 9:134,880,810...134,887,523 		JBrowse link
G FCN3 ficolin 3 involved_in NAS (PMID:17215869) ComplexPortal PMID:17215869 NCBI chr 1:27,369,110...27,374,824
Ensembl chr 1:27,369,110...27,374,824 		JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IMP (PMID:21037097) UniProt PMID:21037097 NCBI chr19:35,448,257...35,451,767
Ensembl chr19:35,443,907...35,451,767 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IDA (PMID:15294986) AgBase PMID:15294986 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G MBL2 mannose binding lectin 2 involved_in IDA (PMID:22966085) ComplexPortal PMID:22966085 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IMP (PMID:19358895) ARUK-UCL PMID:19358895 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CGAS cyclic GMP-AMP synthase involved_in TAS
IDA		 (PMID:37403426)
(PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35322803), (PMID:35438208), (PMID:35460603), (PMID:39322678)		 FlyBase
UniProt		 PMID:32911482 PMID:32912999 PMID:33542149 PMID:35322803 PMID:35438208 More... NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G DDX41 DEAD-box helicase 41 involved_in IDA (PMID:35613581) UniProt PMID:35613581 NCBI chr 5:177,511,577...177,516,961
Ensembl chr 5:177,511,577...177,516,961 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in TAS (PMID:37403426) FlyBase PMID:37403426 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA
TAS
IDA		 (PMID:37403426)
(PMID:25636800), (PMID:30842659), (PMID:30842662), (PMID:35388221), (PMID:37832545)		 Ensembl
FlyBase
UniProt		 PMID:25636800 PMID:30842659 PMID:30842662 PMID:35388221 PMID:37403426 More... GO_REF:0000107 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in TAS (PMID:37403426) FlyBase PMID:37403426 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPK1 alpha kinase 1 involved_in TAS
IBA
IDA		 (PMID:28222186), (PMID:28877472), (PMID:30111836) Reactome
GO_Central
UniProt		 PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000033 Reactome:R-HSA-9645460 NCBI chr 4:112,297,369...112,442,621
Ensembl chr 4:112,285,509...112,442,621 		JBrowse link
G BECN1 beclin 1 involved_in IDA (PMID:34796041) UniProt PMID:34796041 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IDA (PMID:23258413) UniProt PMID:23258413 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IMP
IBA		 (PMID:19211564) UniProt
GO_Central		 PMID:19211564 GO_REF:0000033 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 involved_in TAS (PMID:21616437) UniProt PMID:21616437 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G IPO5 importin 5 involved_in IDA (PMID:31340999) UniProt PMID:31340999 NCBI chr13:97,953,675...98,024,296
Ensembl chr13:97,953,658...98,024,296 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IDA (PMID:8524823) UniProt PMID:8524823 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in IDA (PMID:21931555) UniProt PMID:21931555 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-9645460 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IDA (PMID:16125763), (PMID:20451243) UniProt PMID:16125763 PMID:20451243 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G RIGI RNA sensor RIG-I involved_in TAS
IBA
IDA		 (PMID:21616437)
(PMID:19576794)		 UniProt
GO_Central		 PMID:19576794 PMID:21616437 GO_REF:0000033 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IDA (PMID:23910378), (PMID:35388221) UniProt PMID:23910378 PMID:35388221 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IDA (PMID:29441066) UniProt PMID:29441066 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TIFA TRAF interacting protein with forkhead associated domain involved_in IDA
IBA		 (PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836) UniProt
GO_Central		 PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000033 NCBI chr 4:112,274,537...112,285,904
Ensembl chr 4:112,272,968...112,285,955 		JBrowse link
G TRAF3IP3 TRAF3 interacting protein 3 involved_in IDA
IBA		 (PMID:31390091) UniProt
GO_Central		 PMID:31390091 GO_REF:0000033 NCBI chr 1:209,756,053...209,782,310
Ensembl chr 1:209,756,032...209,782,320 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS
IDA		 (PMID:20501938), (PMID:23015697) Reactome
UniProt		 PMID:20501938 PMID:23015697 Reactome:R-HSA-9645460 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRIM25 tripartite motif containing 25 involved_in IDA (PMID:17392790) UniProt PMID:17392790 NCBI chr17:56,887,909...56,914,049
Ensembl chr17:56,836,387...56,914,080 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IDA (PMID:22607805) UniProt PMID:22607805 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222 		JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WASHC4 WASH complex subunit 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:33749590) MGI
Ensembl		 PMID:33749590 GO_REF:0000107 NCBI chr12:105,107,731...105,169,130
Ensembl chr12:105,107,324...105,169,130 		JBrowse link
inflammasome-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ELP6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within ISO (PMID:30097576) MGI PMID:30097576 NCBI chr 3:47,495,640...47,513,712
Ensembl chr 3:47,495,640...47,513,712 		JBrowse link
innate immune response activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRA2 leukocyte immunoglobulin like receptor A2 involved_in IDA (PMID:27572839) UniProt PMID:27572839 NCBI chr19:54,572,988...54,590,287
Ensembl chr19:54,572,920...54,590,287 		JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HCK HCK proto-oncogene, Src family tyrosine kinase involved_in TAS (PMID:18538446) UniProt PMID:18538446 NCBI chr20:32,052,242...32,101,856
Ensembl chr20:32,052,197...32,101,856 		JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFIH1 interferon induced with helicase C domain 1 involved_in IDA
IBA
IMP		 (PMID:17600090), (PMID:33727702)
(PMID:19211564)		 UniProt
GO_Central		 PMID:17600090 PMID:19211564 PMID:33727702 GO_REF:0000033 NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in TAS (PMID:16979567) UniProt PMID:16979567 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in TAS (PMID:16979567) UniProt PMID:16979567 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,938,474...112,973,251
Ensembl chr12:112,938,051...112,976,460 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr 3:37,052,626...37,176,360
Ensembl chr 3:37,052,626...37,183,689 		JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-166058 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IDA (PMID:16148103) BHF-UCL PMID:16148103 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in TAS (PMID:10383454) BHF-UCL PMID:10383454 Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in TAS (PMID:10383454) BHF-UCL PMID:10383454 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in TAS (PMID:10383454) BHF-UCL PMID:10383454 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in TAS (PMID:21269878) UniProt PMID:21269878 Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14764662)
(PMID:12872135)
(PMID:12719478)		 InterPro
MGI
Ensembl		 PMID:12719478 PMID:12872135 PMID:14764662 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G REG3G regenerating family member 3 gamma involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:79,025,702...79,028,501
Ensembl chr 2:79,025,686...79,028,505 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in TAS (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IBA
IEA
IDA		 (PMID:20037584) ARUK-UCL
GO_Central
Ensembl
ComplexPortal		 PMID:20037584 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in IDA
ISS		 (PMID:20037584) ComplexPortal
ARUK-UCL		 PMID:20037584 GO_REF:0000024 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:151,029,943...151,087,685
Ensembl chr 5:151,029,945...151,093,577 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-166058 Reactome:R-HSA-975871 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRFIP2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chr 3:37,052,626...37,176,360
Ensembl chr 3:37,052,626...37,183,689 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12855817)
(PMID:12872135)		 Ensembl
MGI		 PMID:12855817 PMID:12872135 GO_REF:0000107 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IDA (PMID:17088249) UniProt PMID:17088249 NCBI chr 4:121,131,408...121,227,483
Ensembl chr 4:121,131,408...121,227,466 		JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFI16 interferon gamma inducible protein 16 involved_in IDA (PMID:30104205) UniProt PMID:30104205 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G PYDC5 pyrin domain containing 5 involved_in IDA (PMID:24531343) UniProt PMID:24531343 NCBI chr 1:158,999,971...159,002,751
Ensembl chr 1:158,999,971...159,002,751 		JBrowse link
G TRIM11 tripartite motif containing 11 involved_in IDA (PMID:27498865) UniProt PMID:27498865 NCBI chr 1:228,393,676...228,406,835
Ensembl chr 1:228,393,673...228,406,835 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AARS2 alanyl-tRNA synthetase 2, mitochondrial involved_in IDA (PMID:39322678) UniProt PMID:39322678 NCBI chr 6:44,298,731...44,313,347
Ensembl chr 6:44,298,731...44,313,347 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in IDA (PMID:26440888) UniProt PMID:26440888 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AURKB aurora kinase B involved_in IDA (PMID:33542149) UniProt PMID:33542149 NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600 		JBrowse link
G BANF1 barrier to autointegration nuclear assembly factor 1 involved_in IDA (PMID:32792394) UniProt PMID:32792394 NCBI chr11:66,002,079...66,004,149
Ensembl chr11:66,002,228...66,004,149 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IDA (PMID:32911482), (PMID:32912999) UniProt PMID:32911482 PMID:32912999 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G IRGM immunity related GTPase M involved_in IDA (PMID:32715615) UniProt PMID:32715615 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G LYPLAL1 lysophospholipase like 1 involved_in IDA (PMID:37802025) UniProt PMID:37802025 NCBI chr 1:219,173,878...219,445,496
Ensembl chr 1:219,173,869...219,212,865 		JBrowse link
G MIR4691 microRNA 4691 involved_in IMP (PMID:37403426) FlyBase PMID:37403426 NCBI chr11:68,033,897...68,033,981
Ensembl chr11:68,033,897...68,033,981 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IDA (PMID:35460603) UniProt PMID:35460603 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCBP2 poly(rC) binding protein 2 involved_in IDA (PMID:35322803) UniProt PMID:35322803 NCBI chr12:53,452,102...53,481,162
Ensembl chr12:53,452,102...53,481,162 		JBrowse link
G PPP6C protein phosphatase 6 catalytic subunit involved_in IDA (PMID:32474700) UniProt PMID:32474700 NCBI chr 9:125,146,573...125,189,803
Ensembl chr 9:125,146,573...125,189,939 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IDA (PMID:33273464) UniProt PMID:33273464 NCBI chr 8:47,773,111...47,960,136
Ensembl chr 8:47,773,111...47,960,178 		JBrowse link
G SMPDL3A sphingomyelin phosphodiesterase acid like 3A involved_in IMP
IEA		 (PMID:37890481) UniProt
Ensembl		 PMID:37890481 GO_REF:0000107 NCBI chr 6:122,789,258...122,809,720
Ensembl chr 6:122,789,049...122,809,720 		JBrowse link
G SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in IDA (PMID:38418882) UniProt PMID:38418882 NCBI chr16:1,776,712...1,782,571
Ensembl chr16:1,776,712...1,793,700 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in IDA (PMID:33476576) UniProt PMID:33476576 NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645 		JBrowse link
G ZDHHC18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IDA (PMID:35438208) UniProt PMID:35438208 NCBI chr 1:26,826,688...26,857,604
Ensembl chr 1:26,826,688...26,857,604 		JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITCH itchy E3 ubiquitin protein ligase involved_in IDA (PMID:27736772) UniProt PMID:27736772 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G TARBP2 TARBP2 subunit of RISC loading complex involved_in IDA (PMID:30927622) UniProt PMID:30927622 NCBI chr12:53,500,923...53,506,431
Ensembl chr12:53,500,921...53,506,431 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IDA (PMID:27736772) UniProt PMID:27736772 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TSPAN6 tetraspanin 6 involved_in IMP (PMID:22908223) UniProt PMID:22908223 NCBI chr  X:100,627,108...100,637,104
Ensembl chr  X:100,627,108...100,639,991 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IDA (PMID:19164550) UniProt PMID:19164550 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IMP (PMID:21187438) UniProt PMID:21187438 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G RIOK3 RIO kinase 3 involved_in IMP (PMID:25865883) UniProt PMID:25865883 NCBI chr18:23,453,287...23,483,140
Ensembl chr18:23,453,287...23,486,603 		JBrowse link
G TKFC triokinase and FMN cyclase involved_in IDA (PMID:17600090) UniProt PMID:17600090 NCBI chr11:61,333,228...61,353,426
Ensembl chr11:61,333,220...61,353,295 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in IMP (PMID:22043923) UniProt PMID:22043923 NCBI chr17:74,466,373...74,484,798
Ensembl chr17:74,466,399...74,484,798 		JBrowse link
G CD300LF CD300 molecule like family member f involved_in IMP (PMID:22043923) UniProt PMID:22043923 NCBI chr17:74,694,317...74,712,923
Ensembl chr17:74,694,311...74,712,978 		JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SARM1 sterile alpha and TIR motif containing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr17:28,371,694...28,404,049
Ensembl chr17:28,364,356...28,404,049 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD17A abhydrolase domain containing 17A, depalmitoylase involved_in IDA (PMID:38092000) UniProt PMID:38092000 NCBI chr19:1,876,810...1,885,496
Ensembl chr19:1,876,810...1,885,496 		JBrowse link
G CARD8 caspase recruitment domain family member 8 involved_in IDA (PMID:24517500) UniProt PMID:24517500 NCBI chr19:48,203,148...48,255,946
Ensembl chr19:48,180,770...48,255,946 		JBrowse link
G CPTP ceramide-1-phosphate transfer protein involved_in IMP (PMID:29164996) UniProt PMID:29164996 NCBI chr 1:1,324,802...1,328,896
Ensembl chr 1:1,324,756...1,328,896 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in ISS (PMID:34615873) UniProt PMID:34615873 GO_REF:0000024 NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471 		JBrowse link
G FBXL2 F-box and leucine rich repeat protein 2 involved_in IDA (PMID:26037928) UniProt PMID:26037928 NCBI chr 3:33,277,025...33,422,698
Ensembl chr 3:33,277,025...33,403,662 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 involved_in IDA (PMID:36586411) UniProt PMID:36586411 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G IRGM immunity related GTPase M involved_in IDA (PMID:30612879) UniProt PMID:30612879 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IDA (PMID:36586411) UniProt PMID:36586411 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in IMP (PMID:26347139) UniProt PMID:26347139 NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633 		JBrowse link
G MT-RNR2 mitochondrially encoded 16S rRNA involved_in IDA (PMID:32923762) UniProt PMID:32923762 NCBI chr MT:1,671...3,229
Ensembl chr MT:1,671...3,229 		JBrowse link
G NLRC3 NLR family CARD domain containing 3 involved_in IDA (PMID:25277106) UniProt PMID:25277106 NCBI chr16:3,539,033...3,577,403
Ensembl chr16:3,539,033...3,577,403 		JBrowse link
G NLRP2B NLR family pyrin domain containing 2B NOT|involved_in IMP (PMID:24871464) UniProt PMID:24871464 NCBI chr  X:57,677,067...57,680,260
Ensembl chr  X:57,677,067...57,680,260 		JBrowse link
G PYDC1 pyrin domain containing 1 NOT|involved_in IMP (PMID:24871464) UniProt PMID:24871464 NCBI chr16:31,215,962...31,217,135
Ensembl chr16:31,215,962...31,217,135 		JBrowse link
G PYDC2 pyrin domain containing 2 involved_in IMP (PMID:17339483), (PMID:24871464) UniProt PMID:17339483 PMID:24871464 NCBI chr 3:191,461,163...191,461,456
Ensembl chr 3:191,461,163...191,461,456 		JBrowse link
G SIRT2 sirtuin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within
involved_in		 ISS
IMP
IEA		 (PMID:32514138) ARUK-UCL
Ensembl		 PMID:32514138 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (PMID:21048113) UniProt PMID:21048113 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G TRIM31 tripartite motif containing 31 involved_in IDA (PMID:27929086) UniProt PMID:27929086 NCBI chr 6:30,102,897...30,113,090
Ensembl chr 6:30,102,897...30,113,090 		JBrowse link
G ZDHHC12 zinc finger DHHC-type palmitoyltransferase 12 involved_in IDA (PMID:36586411) UniProt PMID:36586411 NCBI chr 9:128,720,873...128,724,127
Ensembl chr 9:128,720,870...128,724,127 		JBrowse link
negative regulation of non-canonical inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IDA (PMID:37962578) UniProt PMID:37962578 NCBI chr  X:71,533,104...71,575,892
Ensembl chr  X:71,533,087...71,575,892 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ERBIN erbb2 interacting protein involved_in IEA
IBA
IMP		 (PMID:16203728) Ensembl
GO_Central
UniProt		 PMID:16203728 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:65,926,575...66,082,546
Ensembl chr 5:65,883,128...66,082,546 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA
IMP		 (PMID:23991106) Ensembl
UniProt		 PMID:23991106 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G ZNRF4 zinc and ring finger 4 involved_in IDA (PMID:28656966) UniProt PMID:28656966 NCBI chr19:5,455,417...5,456,856
Ensembl chr19:5,455,417...5,456,856 		JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IDA (PMID:19164550) UniProt PMID:19164550 NCBI chr17:5,432,777...5,439,155
Ensembl chr17:5,432,777...5,448,830 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
IBA
IDA
IMP		 (PMID:18411269)
(PMID:21187438)		 Ensembl
GO_Central
UniProt		 PMID:18411269 PMID:21187438 GO_REF:0000033 GO_REF:0000107 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G GPATCH3 G-patch domain containing 3 involved_in IEA
IBA
IMP		 (PMID:28414768) InterPro
GO_Central
UniProt		 PMID:28414768 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:26,890,488...26,900,467
Ensembl chr 1:26,890,488...26,900,467 		JBrowse link
G NLRX1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21703540) Ensembl
MGI		 PMID:21703540 GO_REF:0000107 NCBI chr11:119,168,334...119,184,016
Ensembl chr11:119,166,568...119,184,016 		JBrowse link
G NPLOC4 NPL4 homolog, ubiquitin recognition factor involved_in IMP (PMID:26471729) UniProt PMID:26471729 NCBI chr17:81,556,885...81,637,112
Ensembl chr17:81,556,887...81,648,465 		JBrowse link
G RNF125 ring finger protein 125 involved_in IDA (PMID:17460044), (PMID:26471729) UniProt PMID:17460044 PMID:26471729 NCBI chr18:32,018,825...32,088,144
Ensembl chr18:32,018,825...32,088,144 		JBrowse link
G SEC14L1 SEC14 like lipid binding 1 involved_in IMP
IBA		 (PMID:23843640) UniProt
GO_Central		 PMID:23843640 GO_REF:0000033 NCBI chr17:77,088,685...77,217,101
Ensembl chr17:77,088,749...77,217,101 		JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 involved_in IMP (PMID:26471729) UniProt PMID:26471729 NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP
IEA		 (PMID:26599367) UniProt
Ensembl		 PMID:26599367 GO_REF:0000107 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15220916) Ensembl
MGI		 PMID:15220916 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G TLR6 toll like receptor 6 involved_in IGI (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in NAS (PMID:15142865) BHF-UCL PMID:15142865 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2RL1 F2R like trypsin receptor 1 involved_in IMP (PMID:19865078) UniProt PMID:19865078 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IDA (PMID:15474016) BHF-UCL PMID:15474016 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOD1 aconitate decarboxylase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638 		JBrowse link
G BPIFB1 BPI fold containing family B member 1 involved_in IDA
IBA		 (PMID:21900486) UniProt
GO_Central		 PMID:21900486 GO_REF:0000033 NCBI chr20:33,283,214...33,309,871
Ensembl chr20:33,273,480...33,309,871 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IDA (PMID:19948740) UniProt PMID:19948740 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G LILRA2 leukocyte immunoglobulin like receptor A2 involved_in IMP (PMID:22479404) UniProt PMID:22479404 NCBI chr19:54,572,988...54,590,287
Ensembl chr19:54,572,920...54,590,287 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP (PMID:28609714) UniProt PMID:28609714 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G MIR140 microRNA 140 involved_in IGI
IMP		 (PMID:30321456)
(PMID:30233718)		 ARUK-UCL PMID:30233718 PMID:30321456 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR146A microRNA 146a involved_in IC (PMID:21329689) ARUK-UCL PMID:21329689 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR149 microRNA 149 involved_in IMP (PMID:28260877) ARUK-UCL PMID:28260877 NCBI chr 2:240,456,001...240,456,089
Ensembl chr 2:240,456,001...240,456,089 		JBrowse link
G MIR200B microRNA 200b involved_in IDA (PMID:22522429) ARUK-UCL PMID:22522429 NCBI chr 1:1,167,104...1,167,198
Ensembl chr 1:1,167,104...1,167,198 		JBrowse link
G MIR200C microRNA 200c involved_in IDA (PMID:22522429) ARUK-UCL PMID:22522429 NCBI chr12:6,963,699...6,963,766
Ensembl chr12:6,963,699...6,963,766 		JBrowse link
G MIR20A microRNA 20a involved_in IDA (PMID:29653364) ARUK-UCL PMID:29653364 NCBI chr13:91,351,065...91,351,135
Ensembl chr13:91,351,065...91,351,135 		JBrowse link
G MIR708 microRNA 708 involved_in IMP (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr11:79,402,022...79,402,109
Ensembl chr11:79,402,022...79,402,109 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IMP (PMID:18511497) BHF-UCL PMID:18511497 NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,976,740...206,003,395
Ensembl chr 1:205,976,740...206,003,461 		JBrowse link
G SQSTM1 sequestosome 1 involved_in IDA (PMID:31281713) UniProt PMID:31281713 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 involved_in IDA (PMID:28898289) UniProt PMID:28898289 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA (PMID:19412184) UniProt PMID:19412184 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IDA (PMID:19412184) UniProt PMID:19412184 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in NAS (PMID:15142865) BHF-UCL PMID:15142865 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IDA (PMID:28898289) UniProt PMID:28898289 NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,305...116,701,300 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
negative regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRA4 leukocyte immunoglobulin like receptor A4 involved_in IMP (PMID:16735691) UniProt PMID:16735691 NCBI chr19:54,333,185...54,339,162
Ensembl chr19:54,333,185...54,339,162 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRAMD4 GRAM domain containing 4 involved_in IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr22:46,575,744...46,682,756
Ensembl chr22:46,576,012...46,679,790 		JBrowse link
G LILRA4 leukocyte immunoglobulin like receptor A4 involved_in IMP (PMID:16735691) UniProt PMID:16735691 NCBI chr19:54,333,185...54,339,162
Ensembl chr19:54,333,185...54,339,162 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IDA (PMID:14716310) UniProt PMID:14716310 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260 		JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S involved_in IMP (PMID:26231120) UniProt PMID:26231120 NCBI chr19:5,205,508...5,340,812
Ensembl chr19:5,158,495...5,340,812 		JBrowse link
G RAB7B RAB7B, member RAS oncogene family involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,976,740...206,003,395
Ensembl chr 1:205,976,740...206,003,461 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IDA (PMID:20829348) UniProt PMID:20829348 NCBI chr19:3,610,645...3,626,790
Ensembl chr19:3,610,645...3,626,815 		JBrowse link
G GPR108 G protein-coupled receptor 108 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:6,729,914...6,737,580
Ensembl chr19:6,729,914...6,737,580 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:7,312,661...7,315,360
Ensembl chr17:7,311,324...7,315,564 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in ISS
IEA		 (PMID:12150927) BHF-UCL
Ensembl		 PMID:12150927 GO_REF:0000107 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16236719) Ensembl
MGI		 PMID:16236719 GO_REF:0000107 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:27,365,961...27,472,790
Ensembl chr11:27,365,961...27,472,790 		JBrowse link
G LRRC14 leucine rich repeat containing 14 involved_in IDA
IBA		 (PMID:27426725) UniProt
GO_Central		 PMID:27426725 GO_REF:0000033 NCBI chr 8:144,517,992...144,525,178
Ensembl chr 8:144,517,992...144,525,172 		JBrowse link
G MIR140 microRNA 140 ISO RGD PMID:31376096 RGD:329337378 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR17 microRNA 17 involved_in IMP (PMID:26041742) ARUK-UCL PMID:26041742 NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688 		JBrowse link
G MIR19A microRNA 19a involved_in IMP (PMID:26041742) ARUK-UCL PMID:26041742 NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972 		JBrowse link
G NFKBIL1 NFKB inhibitor like 1 involved_in IDA
IBA		 (PMID:20829348) UniProt
GO_Central		 PMID:20829348 GO_REF:0000033 NCBI chr 6:31,546,851...31,558,829
Ensembl chr 6:31,546,870...31,558,829 		JBrowse link
G NLRP2B NLR family pyrin domain containing 2B involved_in IMP (PMID:24871464) UniProt PMID:24871464 NCBI chr  X:57,677,067...57,680,260
Ensembl chr  X:57,677,067...57,680,260 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22763455) Ensembl
MGI		 PMID:22763455 GO_REF:0000107 NCBI chr11:278,407...285,388
Ensembl chr11:278,407...285,388 		JBrowse link
G OTUD4 OTU deubiquitinase 4 involved_in IEA
IBA
IDA		 (PMID:29395066) Ensembl
GO_Central
UniProt		 PMID:29395066 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:145,133,650...145,180,589
Ensembl chr 4:145,110,838...145,180,589 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,190 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G RNF115 ring finger protein 115 involved_in IDA (PMID:35343654) UniProt PMID:35343654 NCBI chr 1:145,738,868...145,824,095
Ensembl chr 1:145,738,868...145,824,095 		JBrowse link
G SMPDL3B sphingomyelin phosphodiesterase acid like 3B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:27,935,000...27,959,152
Ensembl chr 1:27,935,000...27,959,157 		JBrowse link
G TRIM22 tripartite motif containing 22 involved_in ISO (PMID:18345001) UniProt PMID:18345001 NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089 		JBrowse link
G TYRO3 TYRO3 protein tyrosine kinase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:41,559,212...41,583,589
Ensembl chr15:41,557,675...41,583,589 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IDA (PMID:35343654) UniProt PMID:35343654 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222 		JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP1 NLR family pyrin domain containing 1 involved_in IMP
IDA		 (PMID:27662089), (PMID:31484767)
(PMID:22665479), (PMID:33243852), (PMID:33420028), (PMID:33420033), (PMID:33852854), (PMID:35594856)		 UniProt PMID:22665479 PMID:27662089 PMID:31484767 PMID:33243852 PMID:33420028 More... NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 6:30,626,874...30,646,821
Ensembl chr 6:30,626,842...30,646,823 		JBrowse link
G GKN2 gastrokine 2 acts_upstream_of_or_within ISO (PMID:32226647) MGI PMID:32226647 NCBI chr 2:68,945,232...68,952,893
Ensembl chr 2:68,945,232...68,952,893 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28928055) Ensembl
MGI		 PMID:28928055 GO_REF:0000107 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
IDA
ISO		 (PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502), (PMID:39173637)
(PMID:22753929)		 Ensembl
UniProt
MGI		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:27043286 More... GO_REF:0000107 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IDA (PMID:27432880) UniProt PMID:27432880 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G SIRT2 sirtuin 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP6 NLR family pyrin domain containing 6 involved_in IDA
IEA		 (PMID:30674671), (PMID:31932628), (PMID:34678144) UniProt
Ensembl		 PMID:30674671 PMID:31932628 PMID:34678144 GO_REF:0000107 NCBI chr11:278,407...285,388
Ensembl chr11:278,407...285,388 		JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYLD CYLD lysine 63 deubiquitinase involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr16:50,742,086...50,801,935
Ensembl chr16:50,742,050...50,801,935 		JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773 		JBrowse link
G MAP2K6 mitogen-activated protein kinase kinase 6 involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr17:69,414,697...69,553,865
Ensembl chr17:69,414,697...69,553,865 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G RNF34 ring finger protein 34 involved_in IMP (PMID:25012219) UniProt PMID:25012219 NCBI chr12:121,400,118...121,424,348
Ensembl chr12:121,400,083...121,430,623 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in TAS Reactome Reactome:R-HSA-168638 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in IDA
IEA		 (PMID:11058605), (PMID:12791997), (PMID:12796777) UniProt
Ensembl		 PMID:11058605 PMID:12791997 PMID:12796777 GO_REF:0000107 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:11894098)
(PMID:29452636), (PMID:30279485)		 Ensembl
MGI
UniProt		 PMID:11894098 PMID:29452636 PMID:30279485 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IDA (PMID:29452636) UniProt PMID:29452636 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INAVA innate immunity activator involved_in IMP (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:200,891,531...200,915,742
Ensembl chr 1:200,891,048...200,915,742 		JBrowse link
G IRGM immunity related GTPase M involved_in IMP (PMID:25891078) UniProt PMID:25891078 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G LACC1 laccase domain containing 1 involved_in IDA (PMID:31875558) UniProt PMID:31875558 NCBI chr13:43,879,178...43,893,932
Ensembl chr13:43,879,284...43,893,932 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 IDA
IEA		 (PMID:12527755)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195)		 MGI
UniProt
Ensembl		 PMID:12527755 PMID:12626759 PMID:15044951 PMID:17355968 PMID:23806334 More... GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity involved_in IMP (PMID:23806334) UniProt PMID:23806334 NCBI chr 5:14,664,718...14,716,525
Ensembl chr 5:14,664,664...14,716,529 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within IDA (PMID:12527755) MGI PMID:12527755 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:11894098)
(PMID:16824733), (PMID:17355968), (PMID:17562858), (PMID:23806334), (PMID:28545134), (PMID:29452636), (PMID:30026309), (PMID:30279485), (PMID:30478312)		 Ensembl
MGI
UniProt		 PMID:11894098 PMID:16824733 PMID:17355968 PMID:17562858 PMID:23806334 More... GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IDA (PMID:19667203), (PMID:22607974), (PMID:29452636) UniProt PMID:19667203 PMID:22607974 PMID:29452636 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 involved_in NAS (PMID:29247998) ComplexPortal PMID:29247998 NCBI chr 1:159,055,051...159,147,132
Ensembl chr 1:159,056,129...159,187,843 		JBrowse link
G CASP1 caspase 1 involved_in NAS (PMID:21918512), (PMID:22258606), (PMID:29196474), (PMID:29247998) ComplexPortal PMID:21918512 PMID:22258606 PMID:29196474 PMID:29247998 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CGAS cyclic GMP-AMP synthase involved_in IDA (PMID:23258413) UniProt PMID:23258413 NCBI chr 6:73,423,711...73,452,297
Ensembl chr 6:73,413,515...73,452,297 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E involved_in IMP (PMID:24101491) UniProt PMID:24101491 NCBI chr12:8,533,275...8,540,905
Ensembl chr12:8,533,305...8,540,905 		JBrowse link
G INAVA innate immunity activator involved_in IMP (PMID:28436939) UniProt PMID:28436939 NCBI chr 1:200,891,531...200,915,742
Ensembl chr 1:200,891,048...200,915,742 		JBrowse link
G LACC1 laccase domain containing 1 involved_in IDA (PMID:28593945), (PMID:31875558) UniProt PMID:28593945 PMID:31875558 NCBI chr13:43,879,178...43,893,932
Ensembl chr13:43,879,284...43,893,932 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in NAS (PMID:29196474) ComplexPortal PMID:29196474 NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein involved_in NAS (PMID:21918512) ComplexPortal PMID:21918512 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,166...71,025,339 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in NAS (PMID:21918512) ComplexPortal PMID:21918512 NCBI chr 2:32,224,449...32,265,743
Ensembl chr 2:32,224,453...32,265,732 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 involved_in NAS (PMID:22258606) ComplexPortal PMID:22258606 NCBI chr17:5,501,396...5,584,509
Ensembl chr17:5,499,415...5,619,424 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in NAS (PMID:22258606) ComplexPortal PMID:22258606 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 involved_in IDA (PMID:31649195) UniProt PMID:31649195 NCBI chr 7:30,424,527...30,478,784
Ensembl chr 7:30,424,527...30,478,784 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IDA (PMID:31649195) UniProt PMID:31649195 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in NAS (PMID:21918512), (PMID:22258606), (PMID:29196474), (PMID:29247998) ComplexPortal PMID:21918512 PMID:22258606 PMID:29196474 PMID:29247998 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RNF144A ring finger protein 144A involved_in IDA (PMID:37955227) UniProt PMID:37955227 NCBI chr 2:6,917,412...7,076,367
Ensembl chr 2:6,917,412...7,068,286 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IDA (PMID:23910378) UniProt PMID:23910378 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBP2 guanylate binding protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
positive regulation of antifungal innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G5 phospholipase A2 group V involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr11:47,354,860...47,378,547
Ensembl chr11:47,354,860...47,409,369 		JBrowse link
G TRIM62 tripartite motif containing 62 involved_in IDA
IEA		 (PMID:26488816) UniProt
Ensembl		 PMID:26488816 GO_REF:0000107 NCBI chr 1:33,145,399...33,182,043
Ensembl chr 1:33,145,399...33,182,059 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase involved_in IDA (PMID:25704810) UniProt PMID:25704810 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IDA (PMID:37832545) UniProt PMID:37832545 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 involved_in IMP (PMID:36745868) UniProt PMID:36745868 NCBI chr21:45,502,517...45,563,025
Ensembl chr21:45,493,572...45,573,365 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in IDA (PMID:37832545) UniProt PMID:37832545 NCBI chr22:39,399,780...39,437,132
Ensembl chr22:39,399,778...39,437,060 		JBrowse link
G ZDHHC9 zinc finger DHHC-type palmitoyltransferase 9 involved_in IDA (PMID:37802025) UniProt PMID:37802025 NCBI chr  X:129,803,288...129,843,886
Ensembl chr  X:129,803,288...129,843,909 		JBrowse link
positive regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR520B microRNA 520b involved_in IDA (PMID:20574151) ARUK-UCL PMID:20574151 NCBI chr19:53,701,227...53,701,287
Ensembl chr19:53,701,227...53,701,287 		JBrowse link
G MIR520E microRNA 520e involved_in IDA (PMID:20574151) ARUK-UCL PMID:20574151 NCBI chr19:53,675,711...53,675,797
Ensembl chr19:53,675,711...53,675,797 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IDA (PMID:22328336) UniProt PMID:22328336 NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in IMP (PMID:21791617) UniProt PMID:21791617 NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G USP17L2 ubiquitin specific peptidase 17 like family member 2 (gene/pseudogene) involved_in IMP (PMID:20368735) UniProt PMID:20368735 NCBI chr 8:12,136,435...12,138,849
Ensembl chr 8:12,136,435...12,138,849 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD160 CD160 molecule involved_in IDA (PMID:17307798) UniProt PMID:17307798 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
G CD226 CD226 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24658051) InterPro
MGI
Ensembl		 PMID:24658051 GO_REF:0000002 GO_REF:0000107 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G CLNK cytokine dependent hematopoietic cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:10,486,395...10,734,846
Ensembl chr 4:10,486,395...10,684,768 		JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:15100275 RGD:2303778 NCBI chr 7:150,737,418...150,743,646
Ensembl chr 7:150,722,253...150,750,033 		JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:30134159) UniProt PMID:30134159 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G HLA-F major histocompatibility complex, class I, F involved_in IDA (PMID:27455421) UniProt PMID:27455421 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
G HLA-G major histocompatibility complex, class I, G involved_in IDA (PMID:16366734), (PMID:19304799), (PMID:23184984) UniProt PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G IL21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) MGI PMID:14764669 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G KIR2DL4 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 involved_in IDA (PMID:16366734), (PMID:19304799), (PMID:23184984) UniProt PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr19:54,803,610...54,814,517
Ensembl chr19:54,803,610...54,814,517 		JBrowse link
G RAET1G retinoic acid early transcript 1G involved_in IDA (PMID:18544572) UniProt PMID:18544572 NCBI chr 6:149,916,878...149,923,121
Ensembl chr 6:149,916,878...149,923,121 		JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1G1 adaptor related protein complex 1 subunit gamma 1 involved_in IMP (PMID:23632890) UniProt PMID:23632890 NCBI chr16:71,729,000...71,808,834
Ensembl chr16:71,729,000...71,809,201 		JBrowse link
G CD160 CD160 molecule involved_in IDA (PMID:19109136) UniProt PMID:19109136 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
G HLA-F major histocompatibility complex, class I, F involved_in IDA (PMID:27455421) UniProt PMID:27455421 NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in IDA (PMID:21825173) UniProt PMID:21825173 NCBI chr12:10,430,599...10,436,010
Ensembl chr12:10,426,854...10,442,300 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IMP (PMID:23632890) UniProt PMID:23632890 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1G1 adaptor related protein complex 1 subunit gamma 1 involved_in IMP (PMID:23632890) UniProt PMID:23632890 NCBI chr16:71,729,000...71,808,834
Ensembl chr16:71,729,000...71,809,201 		JBrowse link
G BID BH3 interacting domain death agonist ISO RGD PMID:17893612 RGD:408346749 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CADM1 cell adhesion molecule 1 involved_in ISS
IDA		 (PMID:12826663)
(PMID:15811952)		 UniProt PMID:12826663 PMID:15811952 NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957 		JBrowse link
G CD160 CD160 molecule involved_in IDA (PMID:12486241), (PMID:17307798) UniProt PMID:12486241 PMID:17307798 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
G CD226 CD226 molecule involved_in IMP (PMID:16304049) BHF-UCL PMID:16304049 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule involved_in IEA
IDA		 (PMID:15811952) Ensembl
HGNC-UCL		 PMID:15811952 GO_REF:0000107 NCBI chr11:122,838,500...122,872,643
Ensembl chr11:122,838,500...122,872,643 		JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:15100275 RGD:2303778 NCBI chr 7:150,737,418...150,743,646
Ensembl chr 7:150,722,253...150,750,033 		JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:23335510) UniProt PMID:23335510 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G HLA-G major histocompatibility complex, class I, G acts_upstream_of_or_within ISO (PMID:16476767) MGI PMID:16476767 NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125 		JBrowse link
G IL12A interleukin 12A involved_in IDA (PMID:2204066) UniProt PMID:2204066 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL18RAP interleukin 18 receptor accessory protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15843532) Ensembl
MGI		 PMID:15843532 GO_REF:0000107 NCBI chr 2:102,418,621...102,452,565
Ensembl chr 2:102,418,689...102,452,565 		JBrowse link
G IL21 interleukin 21 involved_in
acts_upstream_of_or_within		 IDA
IBA
ISO		 (PMID:18005035)
(PMID:14764669)		 CACAO
GO_Central
MGI		 PMID:14764669 PMID:18005035 GO_REF:0000033 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in IDA
IBA		 (PMID:9754572) UniProt
GO_Central		 PMID:9754572 GO_REF:0000033 NCBI chr12:10,430,599...10,436,010
Ensembl chr12:10,426,854...10,442,300 		JBrowse link
G KLRC3 killer cell lectin like receptor C3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,412,315...10,420,595
Ensembl chr12:10,412,315...10,420,595 		JBrowse link
G KLRC4 killer cell lectin like receptor C4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,407,384...10,409,757
Ensembl chr12:10,403,059...10,409,757 		JBrowse link
G KLRC4-KLRK1 KLRC4-KLRK1 readthrough involved_in IDA
IBA
IEA		 (PMID:15294961) UniProt
GO_Central
InterPro
Ensembl		 PMID:15294961 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in IDA
IBA		 (PMID:9754572) UniProt
GO_Central		 PMID:9754572 GO_REF:0000033 NCBI chr12:10,238,961...10,329,608
Ensembl chr12:10,226,058...10,329,608 		JBrowse link
G KLRF2 killer cell lectin like receptor F2 acts_upstream_of_or_within ISO (PMID:10229823), (PMID:10229828) MGI PMID:10229823 PMID:10229828 NCBI chr12:9,881,489...9,895,833
Ensembl chr12:9,881,489...9,895,833 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:12645935)
(PMID:15294961)		 Ensembl
MGI
GO_Central
InterPro
UniProt		 PMID:12645935 PMID:15294961 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G LAG3 lymphocyte activating 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8602528) Ensembl
MGI		 PMID:8602528 GO_REF:0000107 NCBI chr12:6,772,520...6,778,455
Ensembl chr12:6,772,512...6,778,455 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IMP (PMID:23632890) UniProt PMID:23632890 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G NCR3 natural cytotoxicity triggering receptor 3 involved_in IEA
IBA
IMP		 (PMID:16304049) InterPro
GO_Central
BHF-UCL		 PMID:16304049 GO_REF:0000002 GO_REF:0000033 NCBI chr 6:31,588,895...31,593,006
Ensembl chr 6:31,588,895...31,593,006 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IMP (PMID:16304049) BHF-UCL PMID:16304049 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IMP (PMID:16304049) BHF-UCL PMID:16304049 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G RAET1E retinoic acid early transcript 1E involved_in IDA (PMID:18544572) UniProt PMID:18544572 NCBI chr 6:149,883,179...149,898,113
Ensembl chr 6:149,883,179...149,898,113 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IMP (PMID:19933860) UniProt PMID:19933860 NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575 		JBrowse link
G SH2D1A SH2 domain containing 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19648922)
(PMID:16127454)		 Ensembl
MGI		 PMID:16127454 PMID:19648922 GO_REF:0000107 NCBI chr  X:124,346,563...124,373,160
Ensembl chr  X:124,227,868...124,373,197 		JBrowse link
G SH2D1B SH2 domain containing 1B acts_upstream_of_or_within ISO (PMID:19648922)
(PMID:20962259)		 MGI PMID:19648922 PMID:20962259 NCBI chr 1:162,395,268...162,412,136
Ensembl chr 1:162,395,268...162,412,138 		JBrowse link
G SLAMF6 SLAM family member 6 involved_in IDA (PMID:16920955) UniProt PMID:16920955 NCBI chr 1:160,485,036...160,523,255
Ensembl chr 1:160,485,030...160,523,262 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:9841920) MGI PMID:9841920 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9841920) Ensembl
MGI		 PMID:9841920 GO_REF:0000107 NCBI chr17:42,199,177...42,288,370
Ensembl chr17:42,199,176...42,288,633 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20962259) Ensembl
MGI		 PMID:20962259 GO_REF:0000107 NCBI chr19:6,772,708...6,857,361
Ensembl chr19:6,772,708...6,857,366 		JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD226 CD226 molecule involved_in IMP (PMID:12913096) BHF-UCL PMID:12913096 NCBI chr18:69,853,274...69,961,773
Ensembl chr18:69,831,158...69,961,803 		JBrowse link
G CRTAM cytotoxic and regulatory T cell molecule involved_in IDA
IBA
IEA		 (PMID:15811952) HGNC-UCL
GO_Central
Ensembl		 PMID:15811952 GO_REF:0000033 GO_REF:0000107 NCBI chr11:122,838,500...122,872,643
Ensembl chr11:122,838,500...122,872,643 		JBrowse link
G IL12A interleukin 12A involved_in IDA (PMID:7903063) UniProt PMID:7903063 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL12B interleukin 12B involved_in IDA (PMID:7903063) UniProt PMID:7903063 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 ISO RGD PMID:16323246 RGD:9685180 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IMP
IBA		 (PMID:12913096) BHF-UCL
GO_Central		 PMID:12913096 GO_REF:0000033 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IMP (PMID:12913096) BHF-UCL PMID:12913096 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD160 CD160 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288 		JBrowse link
positive regulation of natural killer cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPP4 dipeptidyl peptidase 4 ISO RGD PMID:19327106 RGD:41408336 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394 		JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:9754572) UniProt PMID:9754572 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194 		JBrowse link
G RASGRP4 RAS guanyl releasing protein 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,409,058...38,426,219
Ensembl chr19:38,409,051...38,426,305 		JBrowse link
G SH2D1B SH2 domain containing 1B involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:162,395,268...162,412,136
Ensembl chr 1:162,395,268...162,412,138 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATAT1 alpha tubulin acetyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23502856) Ensembl
MGI		 PMID:23502856 GO_REF:0000107 NCBI chr 6:30,626,874...30,646,821
Ensembl chr 6:30,626,842...30,646,823 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
IDA		 (PMID:28943315) UniProt PMID:28943315 GO_REF:0000024 NCBI chr  X:155,071,508...155,123,077
Ensembl chr  X:155,071,420...155,123,077 		JBrowse link
G BTK Bruton tyrosine kinase involved_in IDA
IEA		 (PMID:34554188) UniProt
Ensembl		 PMID:34554188 GO_REF:0000107 NCBI chr  X:101,349,450...101,390,796
Ensembl chr  X:101,349,338...101,390,796 		JBrowse link
G CASP4 caspase 4 involved_in ISO (PMID:26173909) UniProt PMID:26173909 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G DHX33 DEAH-box helicase 33 involved_in IDA (PMID:23871209) UniProt PMID:23871209 NCBI chr17:5,440,917...5,468,982
Ensembl chr17:5,440,917...5,468,982 		JBrowse link
G GBP5 guanylate binding protein 5 involved_in IDA (PMID:22461501) UniProt PMID:22461501 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860 		JBrowse link
G KCNK6 potassium two pore domain channel subfamily K member 6 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:38,319,845...38,332,076
Ensembl chr19:38,319,845...38,332,076 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IDA (PMID:39173637) UniProt PMID:39173637 NCBI chr 6:149,658,153...149,718,101
Ensembl chr 6:149,658,153...149,718,105 		JBrowse link
G LATS2 large tumor suppressor kinase 2 involved_in IDA (PMID:39173637) UniProt PMID:39173637 NCBI chr13:20,973,036...21,061,586
Ensembl chr13:20,973,036...21,061,586 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in IDA (PMID:28943315) UniProt PMID:28943315 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MARK4 microtubule affinity regulating kinase 4 involved_in IEA
IDA		 (PMID:28656979) Ensembl
UniProt		 PMID:28656979 GO_REF:0000107 NCBI chr19:45,251,271...45,305,284
Ensembl chr19:45,079,288...45,305,284 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IDA (PMID:23582325) UniProt PMID:23582325 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MIR21 microRNA 21 ISO RGD PMID:29084974 RGD:41404715 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IMP (PMID:33718825) UniProt PMID:33718825 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA
IDA
IBA		 (PMID:31189953), (PMID:36442502), (PMID:39173637) Ensembl
UniProt
GO_Central		 PMID:31189953 PMID:36442502 PMID:39173637 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:198,156,998...198,322,420
Ensembl chr 1:198,156,994...198,322,420 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G PLCG2 phospholipase C gamma 2 acts_upstream_of_or_within IMP (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chr16:81,739,041...81,962,685
Ensembl chr16:81,738,248...81,962,685 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,193,978...134,226,073 		JBrowse link
G PRKD1 protein kinase D1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:29,576,479...29,927,847
Ensembl chr14:29,576,479...30,191,898 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IDA
IEA		 (PMID:27043286) UniProt
Ensembl		 PMID:27043286 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G STMP1 short transmembrane mitochondrial protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:135,662,514...135,676,416
Ensembl chr 7:135,662,496...135,693,418 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G USP50 ubiquitin specific peptidase 50 acts_upstream_of_or_within
involved_in		 IMP
IEA		 (PMID:28094437) MGI
Ensembl		 PMID:28094437 GO_REF:0000107 NCBI chr15:50,493,025...50,546,666
Ensembl chr15:50,494,018...50,546,708 		JBrowse link
G ZDHHC1 zinc finger DHHC-type containing 1 involved_in IDA (PMID:39173637) UniProt PMID:39173637 NCBI chr16:67,394,152...67,416,477
Ensembl chr16:67,394,152...67,416,833 		JBrowse link
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in IDA (PMID:38092000) UniProt PMID:38092000 NCBI chr11:57,668,114...57,701,182
Ensembl chr11:57,667,747...57,701,182 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC15A4 solute carrier family 15 member 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G SLC46A2 solute carrier family 46 member 2 involved_in IMP (PMID:28539433) FlyBase PMID:28539433 NCBI chr 9:112,878,920...112,890,876
Ensembl chr 9:112,878,920...112,890,876 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in IMP (PMID:24790089) UniProt PMID:24790089 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B involved_in IMP (PMID:24790089) UniProt PMID:24790089 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254 		JBrowse link
G NAGK N-acetylglucosamine kinase involved_in IDA (PMID:36002575) UniProt PMID:36002575 NCBI chr 2:71,068,296...71,079,808
Ensembl chr 2:71,064,344...71,079,808 		JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337 		JBrowse link
G SLC15A3 solute carrier family 15 member 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:60,937,084...60,952,176
Ensembl chr11:60,937,060...60,952,653 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZDHHC5 zinc finger DHHC-type palmitoyltransferase 5 involved_in IMP
IBA
IEA		 (PMID:31649195) UniProt
GO_Central
Ensembl		 PMID:31649195 GO_REF:0000033 GO_REF:0000107 NCBI chr11:57,668,114...57,701,182
Ensembl chr11:57,667,747...57,701,182 		JBrowse link
positive regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LBP lipopolysaccharide binding protein involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G RPS19 ribosomal protein S19 involved_in IDA (PMID:15750715) UniProt PMID:15750715 NCBI chr19:41,860,255...41,872,925
Ensembl chr19:41,860,255...41,872,925 		JBrowse link
positive regulation of response to type II interferon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPX hemopexin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18641331) Ensembl
MGI		 PMID:18641331 GO_REF:0000107 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD17 ankyrin repeat domain 17 involved_in IDA (PMID:22328336) UniProt PMID:22328336 NCBI chr 4:73,073,376...73,258,798
Ensembl chr 4:73,073,376...73,258,798 		JBrowse link
G DDX60 DExD/H-box helicase 60 involved_in IMP (PMID:21791617) UniProt PMID:21791617 NCBI chr 4:168,216,294...168,325,979
Ensembl chr 4:168,216,291...168,318,883 		JBrowse link
G DHX58 DExH-box helicase 58 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:42,101,411...42,112,714
Ensembl chr17:42,101,404...42,112,714 		JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like involved_in IDA (PMID:25925578) ARUK-UCL PMID:25925578 NCBI chr12:121,017,761...121,039,246
Ensembl chr12:121,017,763...121,039,246 		JBrowse link
G PUM1 pumilio RNA binding family member 1 involved_in IDA (PMID:25340845) UniProt PMID:25340845 NCBI chr 1:30,931,506...31,065,717
Ensembl chr 1:30,931,506...31,065,991 		JBrowse link
G PUM2 pumilio RNA binding family member 2 involved_in IDA (PMID:25340845) UniProt PMID:25340845 NCBI chr 2:20,248,691...20,352,253
Ensembl chr 2:20,248,691...20,352,234 		JBrowse link
G TRIM15 tripartite motif containing 15 involved_in IMP (PMID:23077300) UniProt PMID:23077300 NCBI chr 6:30,163,546...30,172,693
Ensembl chr 6:30,163,206...30,172,693 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IDA (PMID:24399297) CACAO PMID:24399297 NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431 		JBrowse link
G USP17L2 ubiquitin specific peptidase 17 like family member 2 (gene/pseudogene) involved_in IMP (PMID:20368735) UniProt PMID:20368735 NCBI chr 8:12,136,435...12,138,849
Ensembl chr 8:12,136,435...12,138,849 		JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 involved_in IMP (PMID:21102435) UniProt PMID:21102435 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,132,122 		JBrowse link
G ZCCHC3 zinc finger CCHC-type containing 3 involved_in IDA
IBA		 (PMID:30193849) UniProt
GO_Central		 PMID:30193849 GO_REF:0000033 NCBI chr20:297,570...300,321
Ensembl chr20:297,570...300,321 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREML4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chr 6:41,228,349...41,238,882
Ensembl chr 6:41,228,339...41,238,882 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYBA cytochrome b-245 alpha chain involved_in IDA (PMID:22423966) UniProt PMID:22423966 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IMP (PMID:19865078) UniProt PMID:19865078 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IMP
IEA		 (PMID:26599367), (PMID:28471450) UniProt
Ensembl		 PMID:26599367 PMID:28471450 GO_REF:0000107 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G PJA2 praja ring finger ubiquitin ligase 2 involved_in IMP (PMID:28471450) UniProt PMID:28471450 NCBI chr 5:109,334,722...109,409,974
Ensembl chr 5:109,334,713...109,409,974 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IMP (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR1 toll like receptor 1 involved_in IGI (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IMP (PMID:19865078) UniProt PMID:19865078 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G FLOT1 flotillin 1 involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19734906) Ensembl
MGI		 PMID:19734906 GO_REF:0000107 NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IMP
IEA		 (PMID:23871208) UniProt
Ensembl		 PMID:23871208 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TRIM3 tripartite motif containing 3 involved_in IDA (PMID:32878999) UniProt PMID:32878999 NCBI chr11:6,448,613...6,474,459
Ensembl chr11:6,448,613...6,474,459 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IMP
IBA
IEA		 (PMID:25736436) UniProt
GO_Central
Ensembl		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:223,875,348...223,945,335
Ensembl chr 2:223,855,716...223,945,357 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IDA (PMID:18622013) UniProt PMID:18622013 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:16267105) UniProt PMID:16267105 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IFI35 interferon induced protein 35 involved_in IDA (PMID:29038465) UniProt PMID:29038465 NCBI chr17:43,006,784...43,014,456
Ensembl chr17:43,006,740...43,014,456 		JBrowse link
G LBP lipopolysaccharide binding protein involved_in IDA (PMID:11528597) BHF-UCL PMID:11528597 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LTF lactotransferrin involved_in IMP (PMID:20345905) UniProt PMID:20345905 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
G NINJ1 ninjurin 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:93,121,496...93,134,251
Ensembl chr 9:93,121,496...93,134,251 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IDA (PMID:18511497) BHF-UCL PMID:18511497 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19734906) Ensembl
MGI		 PMID:19734906 GO_REF:0000107 NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA
IMP		 (PMID:23871208) Ensembl
UniProt		 PMID:23871208 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA
IMP		 (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IMP (PMID:19509286) BHF-UCL PMID:19509286 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IMP
IDA		 (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G WDFY1 WD repeat and FYVE domain containing 1 involved_in IEA
IBA
IMP		 (PMID:25736436) Ensembl
GO_Central
UniProt		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:223,875,348...223,945,335
Ensembl chr 2:223,855,716...223,945,357 		JBrowse link
G ZNRF1 zinc and ring finger 1 involved_in IDA (PMID:28593998) UniProt PMID:28593998 NCBI chr16:74,999,024...75,110,994
Ensembl chr16:74,999,024...75,110,994 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in IDA (PMID:30341167) UniProt PMID:30341167 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IMP
IEA		 (PMID:25238095), (PMID:32433612) UniProt
Ensembl		 PMID:25238095 PMID:32433612 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IMP (PMID:32433612) UniProt PMID:32433612 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
G TREML4 triggering receptor expressed on myeloid cells like 4 involved_in IMP
IBA		 (PMID:25848864) UniProt
GO_Central		 PMID:25848864 GO_REF:0000033 NCBI chr 6:41,228,349...41,238,882
Ensembl chr 6:41,228,339...41,238,882 		JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX3X DEAD-box helicase 3 X-linked involved_in IDA (PMID:30341167) UniProt PMID:30341167 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IMP (PMID:32433612) UniProt PMID:32433612 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IMP (PMID:32433612) UniProt PMID:32433612 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:6,865,885...6,898,239
Ensembl chr 2:6,865,557...6,898,239 		JBrowse link
G RTN4 reticulon 4 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:54,972,189...55,137,831
Ensembl chr 2:54,972,187...55,112,621 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in IEA
IMP		 (PMID:25238095) Ensembl
UniProt		 PMID:25238095 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TREML4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (PMID:25848864) UniProt PMID:25848864 NCBI chr 6:41,228,349...41,238,882
Ensembl chr 6:41,228,339...41,238,882 		JBrowse link
G ZDHHC3 zinc finger DHHC-type palmitoyltransferase 3 involved_in IDA (PMID:38169466) UniProt PMID:38169466 NCBI chr 3:44,915,261...44,976,174
Ensembl chr 3:44,915,257...44,976,185 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GDI1 GDP dissociation inhibitor 1 involved_in IDA (PMID:35343654) UniProt PMID:35343654 NCBI chr  X:154,437,154...154,443,467
Ensembl chr  X:154,436,913...154,443,467 		JBrowse link
G LRCH4 leucine rich repeats and calponin homology domain containing 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:100,574,011...100,586,129
Ensembl chr 7:100,574,011...100,586,129 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) UniProt PMID:20728433 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:154,582,057...154,627,997
Ensembl chr 1:154,581,695...154,628,013 		JBrowse link
G FADD Fas associated via death domain involved_in IMP (PMID:21109225) UniProt PMID:21109225 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IEA
IDA		 (PMID:24882218) Ensembl
UniProt		 PMID:24882218 GO_REF:0000107 NCBI chr 1:206,470,476...206,496,889
Ensembl chr 1:206,470,476...206,496,889 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17618271) Ensembl
MGI		 PMID:17618271 GO_REF:0000107 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17618271) Ensembl
MGI		 PMID:17618271 GO_REF:0000107 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22745163) Ensembl
MGI		 PMID:22745163 GO_REF:0000107 NCBI chr19:34,172,504...34,229,288
Ensembl chr19:34,172,504...34,229,288 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IDA (PMID:16127453), (PMID:20451243) BHF-UCL PMID:16127453 PMID:20451243 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IDA (PMID:20061403) UniProt PMID:20061403 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531 		JBrowse link
G RBM47 RNA binding motif protein 47 involved_in IMP (PMID:34160127) UniProt PMID:34160127 NCBI chr 4:40,423,280...40,630,852
Ensembl chr 4:40,423,267...40,630,875 		JBrowse link
G RNF185 ring finger protein 185 involved_in IDA (PMID:28273161) UniProt PMID:28273161 NCBI chr22:31,160,182...31,207,019
Ensembl chr22:31,160,182...31,207,019 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IDA
IEA		 (PMID:23910378) ComplexPortal
Ensembl		 PMID:23910378 GO_REF:0000107 NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TRIM41 tripartite motif containing 41 involved_in IDA (PMID:29760876) UniProt PMID:29760876 NCBI chr 5:181,223,281...181,235,808
Ensembl chr 5:181,222,499...181,235,808 		JBrowse link
G TRIM56 tripartite motif containing 56 involved_in IDA
IBA		 (PMID:29426904) UniProt
GO_Central		 PMID:29426904 GO_REF:0000033 NCBI chr 7:101,085,481...101,097,967
Ensembl chr 7:101,085,481...101,097,967 		JBrowse link
G TRIM6 tripartite motif containing 6 involved_in IMP
IDA
IEA		 (PMID:24882218) UniProt
Ensembl		 PMID:24882218 GO_REF:0000107 NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K involved_in IMP (PMID:24882218) UniProt PMID:24882218 NCBI chr 4:39,698,136...39,782,792
Ensembl chr 4:39,698,109...39,782,792 		JBrowse link
G USP27X ubiquitin specific peptidase 27 X-linked involved_in IDA (PMID:31534008) UniProt PMID:31534008 NCBI chr  X:49,879,484...49,882,558
Ensembl chr  X:49,879,484...49,882,558 		JBrowse link
G USP29 ubiquitin specific peptidase 29 involved_in ISS UniProt GO_REF:0000024 NCBI chr19:57,119,087...57,131,926
Ensembl chr19:57,119,138...57,131,926 		JBrowse link
G WNT5A Wnt family member 5A involved_in IDA (PMID:19399181) BHF-UCL PMID:19399181 NCBI chr 3:55,465,715...55,505,263
Ensembl chr 3:55,465,715...55,490,539 		JBrowse link
G ZBP1 Z-DNA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:17618271) InterPro
MGI
GO_Central		 PMID:17618271 GO_REF:0000002 GO_REF:0000033 NCBI chr20:57,603,852...57,620,426
Ensembl chr20:57,603,846...57,620,576 		JBrowse link
positive regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPX hemopexin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18641331) Ensembl
MGI		 PMID:18641331 GO_REF:0000107 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617 		JBrowse link
G IRGM immunity related GTPase M involved_in IMP (PMID:16888103) UniProt PMID:16888103 NCBI chr 5:150,846,521...150,902,402
Ensembl chr 5:150,846,521...150,900,736 		JBrowse link
G MED1 mediator complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18339625) Ensembl
MGI		 PMID:18339625 GO_REF:0000107 NCBI chr17:39,404,285...39,451,263
Ensembl chr17:39,404,285...39,451,272 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IMP
IDA		 (PMID:20639463)
(PMID:20061403)		 BHF-UCL
UniProt		 PMID:20061403 PMID:20639463 NCBI chr16:56,989,557...57,083,520
Ensembl chr16:56,989,485...57,083,531 		JBrowse link
G PARP9 poly(ADP-ribose) polymerase family member 9 involved_in IMP
IBA
IEA		 (PMID:27796300) UniProt
GO_Central
Ensembl		 PMID:27796300 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:122,527,924...122,564,784
Ensembl chr 3:122,527,924...122,564,577 		JBrowse link
G TXK TXK tyrosine kinase involved_in IDA (PMID:11859127) UniProt PMID:11859127 NCBI chr 4:48,066,393...48,134,250
Ensembl chr 4:48,063,158...48,134,250 		JBrowse link
regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR708 microRNA 708 involved_in IDA (PMID:31599428) ARUK-UCL PMID:31599428 NCBI chr11:79,402,022...79,402,109
Ensembl chr11:79,402,022...79,402,109 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF1 interferon regulatory factor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF7 interferon regulatory factor 7 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983 		JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G KCNK13 potassium two pore domain channel subfamily K member 13 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:90,061,994...90,185,853
Ensembl chr14:90,061,994...90,185,853 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G SLC15A2 solute carrier family 15 member 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:121,894,401...121,944,188
Ensembl chr 3:121,894,401...121,944,188 		JBrowse link
G SLC15A4 solute carrier family 15 member 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC2 baculoviral IAP repeat containing 2 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IMP (PMID:27824081) UniProt PMID:27824081 NCBI chr19:47,745,546...47,757,058
Ensembl chr19:47,745,546...47,757,058 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLOT2 flotillin 2 NOT|involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr17:28,879,339...28,897,733
Ensembl chr17:28,879,335...28,897,733 		JBrowse link
G HCFC2 host cell factor C2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28970238) Ensembl
MGI		 PMID:28970238 GO_REF:0000107 NCBI chr12:104,064,531...104,106,524
Ensembl chr12:104,064,531...104,106,524 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IDA (PMID:37158982) UniProt PMID:37158982 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
G FLOT1 flotillin 1 NOT|involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IDA (PMID:19289601) UniProt PMID:19289601 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FCRL3 Fc receptor like 3 involved_in IDA (PMID:23857366) UniProt PMID:23857366 NCBI chr 1:157,676,481...157,700,956
Ensembl chr 1:157,674,321...157,700,769 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein involved_in IGI (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 involved_in TAS (PMID:20888210) UniProt PMID:20888210 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IGI (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G ESR1 estrogen receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22659029) Ensembl
MGI		 PMID:22659029 GO_REF:0000107 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in IDA (PMID:20547752) UniProt PMID:20547752 NCBI chr 1:92,473,043...92,486,925
Ensembl chr 1:92,473,043...92,486,925 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-9860276 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G MFHAS1 multifunctional ROCO family signaling regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:8,783,354...8,893,630
Ensembl chr 8:8,783,354...8,893,630 		JBrowse link
G MIR146A microRNA 146a involved_in IDA (PMID:16885212) ARUK-UCL PMID:16885212 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G S100A8 S100 calcium binding protein A8 involved_in NAS (PMID:25597447) ComplexPortal PMID:25597447 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073 		JBrowse link
G S100A9 S100 calcium binding protein A9 involved_in NAS (PMID:23123827), (PMID:25597447) ComplexPortal PMID:23123827 PMID:25597447 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766 		JBrowse link
RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLPB ClpB family mitochondrial disaggregase involved_in IDA (PMID:31522117) UniProt PMID:31522117 NCBI chr11:72,285,495...72,434,531
Ensembl chr11:72,285,495...72,434,680 		JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22745163) Ensembl
MGI		 PMID:22745163 GO_REF:0000107 NCBI chr19:34,172,504...34,229,288
Ensembl chr19:34,172,504...34,229,288 		JBrowse link
G MAVS mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,938,474...112,973,251
Ensembl chr12:112,938,051...112,976,460 		JBrowse link
G PHB1 prohibitin 1 involved_in IDA (PMID:31522117) UniProt PMID:31522117 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905 		JBrowse link
G PHB2 prohibitin 2 involved_in IDA (PMID:31522117) UniProt PMID:31522117 NCBI chr12:6,965,327...6,970,753
Ensembl chr12:6,965,327...6,970,780 		JBrowse link
G RIGI RNA sensor RIG-I involved_in IDA
IMP		 (PMID:28469175)
(PMID:19211564)		 UniProt PMID:19211564 PMID:28469175 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348 		JBrowse link
G RNF135 ring finger protein 135 involved_in IMP
IDA		 (PMID:28469175), (PMID:31006531)
(PMID:23950712)		 UniProt PMID:23950712 PMID:28469175 PMID:31006531 NCBI chr17:30,958,921...30,999,911
Ensembl chr17:30,970,984...30,999,911 		JBrowse link
G TRIM25 tripartite motif containing 25 NOT|involved_in IMP (PMID:31006531) UniProt PMID:31006531 NCBI chr17:56,887,909...56,914,049
Ensembl chr17:56,836,387...56,914,080 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC6A C-type lectin domain containing 6A involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,455,962...8,478,330
Ensembl chr12:8,455,962...8,478,330 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr12:10,116,777...10,130,304
Ensembl chr12:10,116,777...10,130,258 		JBrowse link
G CREBBP CREB binding protein involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G EP300 E1A binding protein p300 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G KLRC1 killer cell lectin like receptor C1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,442,264...10,454,685
Ensembl chr12:10,442,264...10,454,685 		JBrowse link
G KLRC2 killer cell lectin like receptor C2 involved_in IDA
IBA		 (PMID:9655483) UniProt
GO_Central		 PMID:9655483 GO_REF:0000033 NCBI chr12:10,430,599...10,436,010
Ensembl chr12:10,426,854...10,442,300 		JBrowse link
G KLRC3 killer cell lectin like receptor C3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,412,315...10,420,595
Ensembl chr12:10,412,315...10,420,595 		JBrowse link
G KLRC4 killer cell lectin like receptor C4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:10,407,384...10,409,757
Ensembl chr12:10,403,059...10,409,757 		JBrowse link
G KLRC4-KLRK1 KLRC4-KLRK1 readthrough involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146
Ensembl chr12:10,372,353...10,410,146 		JBrowse link
G KLRD1 killer cell lectin like receptor D1 involved_in IDA
IBA		 (PMID:9655483) UniProt
GO_Central		 PMID:9655483 GO_REF:0000033 NCBI chr12:10,238,961...10,329,608
Ensembl chr12:10,226,058...10,329,608 		JBrowse link
G KLRK1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12645935) Ensembl
MGI		 PMID:12645935 GO_REF:0000107 NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635 		JBrowse link
G PAK2 p21 (RAC1) activated kinase 2 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr 3:196,739,857...196,832,647
Ensembl chr 3:196,739,857...196,832,647 		JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr  X:110,944,397...111,227,361
Ensembl chr  X:110,944,285...111,227,361 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in ISS
TAS
IEA		 ARUK-UCL
Reactome
Ensembl		 GO_REF:0000024 GO_REF:0000107 Reactome:R-HSA-5621481 NCBI chr16:81,739,041...81,962,685
Ensembl chr16:81,738,248...81,962,685 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in ISS
IEA
TAS		 ARUK-UCL
Ensembl
Reactome		 GO_REF:0000024 GO_REF:0000107 Reactome:R-HSA-5621481 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-5621481 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IDA (PMID:9655483) UniProt PMID:9655483 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIR2DS2 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 involved_in IDA (PMID:9655483) UniProt PMID:9655483
G LOC124900573 killer cell immunoglobulin-like receptor 2DS2 involved_in IDA (PMID:9655483) UniProt PMID:9655483
G TYROBP transmembrane immune signaling adaptor TYROBP involved_in IDA (PMID:9655483) UniProt PMID:9655483 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADM1 cell adhesion molecule 1 involved_in IDA
IBA
ISS		 (PMID:15811952)
(PMID:12826663)		 UniProt
GO_Central		 PMID:12826663 PMID:15811952 GO_REF:0000033 NCBI chr11:115,169,236...115,504,415
Ensembl chr11:115,169,218...115,504,957 		JBrowse link
G NECTIN2 nectin cell adhesion molecule 2 involved_in IMP (PMID:12913096) BHF-UCL PMID:12913096 NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223 		JBrowse link
G PVR PVR cell adhesion molecule involved_in IMP (PMID:12913096) BHF-UCL PMID:12913096 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G ULBP1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) MGI PMID:12645935 NCBI chr 6:149,963,943...149,973,715
Ensembl chr 6:149,963,943...149,973,715 		JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIRAP TIR domain containing adaptor protein involved_in IDA (PMID:11544529) BHF-UCL PMID:11544529 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 IMP
ISO
IBA		 (PMID:10383454)
(PMID:10549626)		 BHF-UCL
MGI
GO_Central		 PMID:10383454 PMID:10549626 GO_REF:0000033 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in IDA (PMID:16116184) UniProt PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15220916) Ensembl
MGI		 PMID:15220916 GO_REF:0000107 NCBI chr16:50,693,606...50,733,075
Ensembl chr16:50,693,588...50,733,077 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IDA (PMID:11894098) MGI PMID:11894098 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G TLR2 toll like receptor 2 involved_in IDA (PMID:17128265) BHF-UCL PMID:17128265 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule involved_in ISO (PMID:25158758) UniProt PMID:25158758 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G COLEC12 collectin subfamily member 12 involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr18:316,737...500,701
Ensembl chr18:316,737...500,722 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-168164 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G LGALS9 galectin 9 involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-168164 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G RFTN1 raftlin, lipid raft linker 1 acts_upstream_of_or_within IMP (PMID:21266579) MGI PMID:21266579 NCBI chr 3:16,315,845...16,513,699
Ensembl chr 3:16,313,574...16,514,026 		JBrowse link
G RNF170 ring finger protein 170 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:31076723) MGI
Ensembl		 PMID:31076723 GO_REF:0000107 NCBI chr 8:42,849,637...42,897,299
Ensembl chr 8:42,849,637...42,897,290 		JBrowse link
G SCARA3 scavenger receptor class A member 3 NOT|involved_in IMP (PMID:25204797) UniProt PMID:25204797 NCBI chr 8:27,633,463...27,734,141
Ensembl chr 8:27,633,868...27,676,776 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IDA (PMID:12471095) UniProt PMID:12471095 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TLR3 toll like receptor 3 involved_in IDA (PMID:17128265), (PMID:18172197) UniProt PMID:17128265 PMID:18172197 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-168164 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IMP
IBA
IEA		 (PMID:18082565) UniProt
GO_Central
Ensembl		 PMID:18082565 GO_REF:0000033 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD14 CD14 molecule involved_in IDA
IBA		 (PMID:27986454) UniProt
GO_Central		 PMID:27986454 GO_REF:0000033 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IDA (PMID:26189595) UniProt PMID:26189595 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G ECSIT ECSIT signaling integrator involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr19:11,505,929...11,529,134
Ensembl chr19:11,505,929...11,529,172 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:10549626) GO_Central
MGI		 PMID:10549626 GO_REF:0000033 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in IDA (PMID:17878161) UniProt PMID:17878161 NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in IC (PMID:35977521) UniProt PMID:35977521 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IDA (PMID:25636800) UniProt PMID:25636800 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G LGALS9 galectin 9 NOT|involved_in IDA (PMID:16116184) UniProt PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA
IBA		 (PMID:16751103) UniProt
GO_Central		 PMID:16751103 GO_REF:0000033 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29624734) Ensembl
MGI		 PMID:29624734 GO_REF:0000107 NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 (PMID:18261938)
(PMID:7479976)		 Ensembl
MGI
UniProt		 PMID:7479976 PMID:18261938 GO_REF:0000107 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NMI N-myc and STAT interactor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:151,270,470...151,289,668
Ensembl chr 2:151,270,470...151,289,894 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IMP (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IDA (PMID:25355951) UniProt PMID:25355951 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894098) Ensembl
MGI		 PMID:11894098 GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064 		JBrowse link
G S100A14 S100 calcium binding protein A14 involved_in IDA
IBA		 (PMID:17625598) UniProt
GO_Central		 PMID:17625598 GO_REF:0000033 NCBI chr 1:153,614,255...153,616,325
Ensembl chr 1:153,614,255...153,616,986 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IDA (PMID:28747347) UniProt PMID:28747347 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IDA (PMID:12471095) UniProt PMID:12471095 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA (PMID:28630139) UniProt PMID:28630139 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIRAP TIR domain containing adaptor protein involved_in IDA
IBA		 (PMID:16751103) UniProt
GO_Central		 PMID:16751103 GO_REF:0000033 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:25549946)
(PMID:10196138), (PMID:15618008), (PMID:18222170)		 Ensembl
MGI
GO_Central
UniProt		 PMID:10196138 PMID:15618008 PMID:18222170 PMID:25549946 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IDA (PMID:28630139) UniProt PMID:28630139 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TMEM126A transmembrane protein 126A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25549946) Ensembl
MGI		 PMID:25549946 GO_REF:0000107 NCBI chr11:85,647,967...85,656,542
Ensembl chr11:85,647,967...85,656,547 		JBrowse link
G TNIP3 TNFAIP3 interacting protein 3 involved_in IDA (PMID:17088249) UniProt PMID:17088249 NCBI chr 4:121,131,408...121,227,483
Ensembl chr 4:121,131,408...121,227,466 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IDA (PMID:18222170) UniProt PMID:18222170 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IDA (PMID:25371197) UniProt PMID:25371197 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TRIL TLR4 interactor with leucine rich repeats involved_in IDA
IBA		 (PMID:19710467) UniProt
GO_Central		 PMID:19710467 GO_REF:0000033 NCBI chr 7:28,953,358...28,958,330
Ensembl chr 7:28,953,358...28,958,330 		JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA (PMID:16751103) UniProt PMID:16751103 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G TIRAP TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) BHF-UCL PMID:12447442 NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845 		JBrowse link
G TLR5 toll like receptor 5 involved_in IDA (PMID:14625549), (PMID:17128265) BHF-UCL PMID:14625549 PMID:17128265 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA
IBA
IDA		 (PMID:12032557) Ensembl
GO_Central		 PMID:12032557 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IMP
IBA
IEA		 (PMID:19006693) UniProt
GO_Central
Ensembl		 PMID:19006693 GO_REF:0000033 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA (PMID:33718825) UniProt PMID:33718825 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G TLR7 toll like receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 involved_in IDA (PMID:12032557), (PMID:24942581), (PMID:33718825) UniProt PMID:12032557 PMID:24942581 PMID:33718825 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPG5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect IMP (PMID:29130391) UniProt PMID:29130391 NCBI chr18:45,800,581...45,967,329
Ensembl chr18:45,800,581...45,967,329 		JBrowse link
G HAVCR2 hepatitis A virus cellular receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:157,085,832...157,109,044
Ensembl chr 5:157,085,422...157,142,869 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in TAS Reactome Reactome:R-HSA-168138 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in TAS Reactome Reactome:R-HSA-168138 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514 		JBrowse link
G TLR9 toll like receptor 9 involved_in IDA (PMID:23857366) UniProt PMID:23857366 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:2,741,648...2,756,336
Ensembl chr 4:2,741,648...2,756,342 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in IMP
ISS
IBA
IEA		 (PMID:19006693) UniProt
GO_Central
Ensembl		 PMID:19006693 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20847273) Ensembl
MGI		 PMID:20847273 GO_REF:0000107 NCBI chr 5:78,000,522...78,294,698
Ensembl chr 5:77,991,640...78,294,762 		JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in IDA (PMID:16831874) UniProt PMID:16831874 NCBI chr 1:85,265,776...85,276,632
Ensembl chr 1:85,265,776...85,276,632 		JBrowse link
G CD86 CD86 molecule acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CTSS cathepsin S involved_in TAS Reactome Reactome:R-HSA-168898 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30990796) Ensembl
MGI		 PMID:30990796 GO_REF:0000107 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in TAS Reactome Reactome:R-HSA-168181 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:27832756 RGD:34888235 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in TAS (PMID:21269878) Reactome PMID:21269878 Reactome:R-HSA-168181 NCBI chr12:43,758,951...43,789,541
Ensembl chr12:43,758,944...43,798,307 		JBrowse link
G LRRC19 leucine rich repeat containing 19 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:19679103) Ensembl
GO_Central
MGI		 PMID:19679103 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:26,993,136...27,005,672
Ensembl chr 9:26,993,136...27,005,672 		JBrowse link
G LY96 lymphocyte antigen 96 involved_in IDA (PMID:14607928) ComplexPortal PMID:14607928 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:206,684,905...206,734,281
Ensembl chr 1:206,684,905...206,734,281 		JBrowse link
G MAPKAPK3 MAPK activated protein kinase 3 involved_in ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:50,611,520...50,649,291
Ensembl chr 3:50,611,520...50,649,291 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:81,739,041...81,962,685
Ensembl chr16:81,738,248...81,962,685 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:20,149,911...20,267,097
Ensembl chr  X:20,149,911...20,267,519 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in IDA (PMID:12471095) UniProt PMID:12471095 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TIFAB TIFA inhibitor involved_in
acts_upstream_of_negative_effect		 IEA
ISO		 (PMID:26458771) Ensembl
MGI		 PMID:26458771 GO_REF:0000107 NCBI chr 5:135,444,226...135,452,351
Ensembl chr 5:135,444,226...135,452,351 		JBrowse link
G TLR1 toll like receptor 1 involved_in ISO
IEA
IBA
ISS
IDA		 (PMID:16893894) RGD
Ensembl
GO_Central
ComplexPortal
InterPro		 PMID:16893894 PMID:16973131 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114 RGD:1643119 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817 		JBrowse link
G TLR10 toll like receptor 10 involved_in IEA
IBA
ISS		 InterPro
GO_Central
ComplexPortal		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000114 NCBI chr 4:38,772,238...38,782,990
Ensembl chr 4:38,772,238...38,782,990 		JBrowse link
G TLR2 toll like receptor 2 involved_in ISO
IBA
IEA
ISS
IDA		 (PMID:16893894) RGD
GO_Central
UniProt
ComplexPortal
Ensembl
InterPro		 PMID:16893894 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000114 RGD:1643119 RGD:5684896 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR3 toll like receptor 3 involved_in ISO
IEA
IDA		 (PMID:18172197) RGD
Ensembl
UniProt
InterPro		 PMID:16973131 PMID:18172197 GO_REF:0000002 GO_REF:0000107 RGD:1643119 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISO
IDA
IEA		 (PMID:14607928) RGD
ComplexPortal
InterPro		 PMID:14607928 PMID:16973131 GO_REF:0000002 RGD:1643119 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR5 toll like receptor 5 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,292 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl
InterPro		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:1643119 RGD:5684896 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TLR7 toll like receptor 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:12,867,072...12,890,361
Ensembl chr  X:12,867,072...12,890,361 		JBrowse link
G TLR8 toll like receptor 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169 		JBrowse link
G TLR9 toll like receptor 9 involved_in ISO
IEA
IBA
IDA		 (PMID:17128265) RGD
Ensembl
GO_Central
BHF-UCL		 PMID:16973131 PMID:17128265 GO_REF:0000033 GO_REF:0000107 RGD:1643119 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA
IDA
ISS		 (PMID:18222170) Ensembl
UniProt		 PMID:18222170 GO_REF:0000024 GO_REF:0000107 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G UNC93B1 unc-93 homolog B1, TLR signaling regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16415873) InterPro
MGI
Ensembl		 PMID:16415873 GO_REF:0000002 GO_REF:0000107 NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982 		JBrowse link
toll-like receptor TLR1:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCIMP SLP adaptor and CSK interacting membrane protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860 		JBrowse link
toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IDA (PMID:36964784) UniProt PMID:36964784 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IDA (PMID:27708357) UniProt PMID:27708357 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TLR2 toll like receptor 2 involved_in IDA (PMID:23626692) ComplexPortal PMID:23626692 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR6 toll like receptor 6 involved_in IDA (PMID:23626692) ComplexPortal PMID:23626692 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCE protein kinase C epsilon involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 involved_in IDA (PMID:30883606) UniProt PMID:30883606 NCBI chr10:118,004,916...118,046,941
Ensembl chr10:118,004,916...118,046,941 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IDA
IMP		 (PMID:19412184)
(PMID:22685567)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IMP
IDA		 (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
TRIF-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule involved_in IDA (PMID:36232715) UniProt PMID:36232715 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD300LF CD300 molecule like family member f involved_in IMP (PMID:22043923) UniProt PMID:22043923 NCBI chr17:74,694,317...74,712,923
Ensembl chr17:74,694,311...74,712,978 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in TAS Reactome Reactome:R-HSA-937061 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IDA (PMID:25636800) UniProt PMID:25636800 NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in TAS Reactome Reactome:R-HSA-937061 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G TICAM1 TIR domain containing adaptor molecule 1 involved_in ISS
IBA
IEA
IMP		 (PMID:25636800) ParkinsonsUK-UCL
GO_Central
InterPro
CACAO
Ensembl		 PMID:25636800 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TLR4 toll like receptor 4 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR6 toll like receptor 6 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817 		JBrowse link
G TMED7-TICAM2 TMED7-TICAM2 readthrough involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:115,578,496...115,626,036
Ensembl chr 5:115,578,642...115,626,161 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in TAS Reactome Reactome:R-HSA-9013973 Reactome:R-HSA-936964 NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in TAS Reactome Reactome:R-HSA-937061 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19710
    response to stimulus 10255
      response to biotic stimulus 2062
        positive regulation of response to biotic stimulus 463
          positive regulation of innate immune response 423
            activation of innate immune response + 345
            positive regulation of age-related resistance 0
            positive regulation of antifungal innate immune response 3
            positive regulation of complement activation, alternative pathway 2
            positive regulation of complement activation, lectin pathway 0
            positive regulation of innate immunity memory response 0
            positive regulation of melanization defense response 0
            positive regulation of natural killer cell mediated immunity + 41
            positive regulation of pattern recognition receptor signaling pathway + 81
            positive regulation of plant-type hypersensitive response 0
            positive regulation of respiratory burst involved in inflammatory response 2
            positive regulation of response to type II interferon + 6
            positive regulation of type I interferon-mediated signaling pathway 21
Path 2
Term Annotations click to browse term
  biological_process 19710
    response to stimulus 10255
      response to external stimulus 2982
        response to external biotic stimulus 2010
          response to other organism 2007
            defense response to other organism 1434
              defense response to symbiont 1318
                innate immune response 1128
                  regulation of innate immune response 516
                    positive regulation of innate immune response 423
                      activation of innate immune response + 345
                      positive regulation of age-related resistance 0
                      positive regulation of antifungal innate immune response 3
                      positive regulation of complement activation, alternative pathway 2
                      positive regulation of complement activation, lectin pathway 0
                      positive regulation of innate immunity memory response 0
                      positive regulation of melanization defense response 0
                      positive regulation of natural killer cell mediated immunity + 41
                      positive regulation of pattern recognition receptor signaling pathway + 81
                      positive regulation of plant-type hypersensitive response 0
                      positive regulation of respiratory burst involved in inflammatory response 2
                      positive regulation of response to type II interferon + 6
                      positive regulation of type I interferon-mediated signaling pathway 21
paths to the root