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Gene: NOD1 (nucleotide binding oligomerization domain containing 1) Homo sapiens
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Symbol: NOD1
Name: nucleotide binding oligomerization domain containing 1
Description: Exhibits CARD domain binding activity and protein homodimerization activity. Involved in several processes, including cellular response to muramyl dipeptide; positive regulation of intracellular signal transduction; and response to bacterium. Localizes to the basolateral plasma membrane and cytoplasm. Implicated in asthma. Biomarker of rhinitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CARD4; caspase recruitment domain family, member 4; caspase recruitment domain-containing protein 4; CLR7.1; NLR family, CARD domain containing 1; NLRC1; nucleotide-binding oligomerization domain containing 1; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1; nucleotide-binding oligomerization domain-containing protein 1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,424,527 - 30,478,866 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37730,464,143 - 30,518,426 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,430,675 - 30,484,790 (-)NCBINCBI36hg18NCBI36
Build 34730,237,389 - 30,291,505NCBI
Celera730,453,464 - 30,507,713 (-)NCBI
Cytogenetic Map7p14.3NCBI
HuRef730,346,423 - 30,400,669 (-)NCBIHuRef
CHM1_1730,464,171 - 30,518,245 (-)NCBICHM1_1
CRA_TCAGchr7v2730,513,913 - 30,568,158 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NOD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344653
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.