Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | LRRFIP2 | Human | (+)-schisandrin B | multiple interactions | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of LRRFIP2 mRNA] | CTD | PMID:31150632 | LRRFIP2 | Human | 1,2-dimethylhydrazine | decreases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of LRRFIP2 mRNA | CTD | PMID:22206623 | LRRFIP2 | Human | 17alpha-ethynylestradiol | multiple interactions | ISO | Lrrfip2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LRRFIP2 mRNA | CTD | PMID:17942748 | LRRFIP2 | Human | 17alpha-ethynylestradiol | affects expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of LRRFIP2 mRNA | CTD | PMID:17555576 | LRRFIP2 | Human | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of LRRFIP2 mRNA | CTD | PMID:22574217 | LRRFIP2 | Human | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of LRRFIP2 mRNA | CTD | PMID:31614463 | LRRFIP2 | Human | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | EXP | | 6480464 | Dihydrotestosterone results in increased expression of LRRFIP2 mRNA | CTD | PMID:29581250 | LRRFIP2 | Human | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Lrrfip2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LRRFIP2 mRNA | CTD | PMID:17942748 | LRRFIP2 | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRRFIP2 mRNA | CTD | PMID:33387578 | LRRFIP2 | Human | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LRRFIP2 mRNA | CTD | PMID:22903824 | LRRFIP2 | Human | 2,6-dinitrotoluene | affects expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of LRRFIP2 mRNA | CTD | PMID:21346803 | LRRFIP2 | Human | 4-hydroxynon-2-enal | increases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in increased expression of LRRFIP2 mRNA | CTD | PMID:19191707 | LRRFIP2 | Human | 4-hydroxyphenyl retinamide | decreases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of LRRFIP2 mRNA | CTD | PMID:28973697 | LRRFIP2 | Human | afimoxifene | multiple interactions | EXP | | 6480464 | afimoxifene inhibits the reaction [Estrogens results in increased expression of LRRFIP2 mRNA] | CTD | PMID:21233418 | LRRFIP2 | Human | amphetamine | increases expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | Amphetamine results in increased expression of LRRFIP2 mRNA | CTD | PMID:30779732 | LRRFIP2 | Human | arsenite(3-) | increases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | arsenite results in increased expression of LRRFIP2 protein | CTD | PMID:37955338 | LRRFIP2 | Human | bisphenol A | increases expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of LRRFIP2 mRNA | CTD | PMID:25181051 more ... | LRRFIP2 | Human | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of LRRFIP2 gene more ... | CTD | PMID:31601247 and PMID:33376534 | LRRFIP2 | Human | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LRRFIP2 protein | CTD | PMID:33376534 | LRRFIP2 | Human | bisphenol A | decreases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of LRRFIP2 mRNA | CTD | PMID:33221593 | LRRFIP2 | Human | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of LRRFIP2 gene | CTD | PMID:31601247 | LRRFIP2 | Human | caffeine | affects phosphorylation | EXP | | 6480464 | Caffeine affects the phosphorylation of LRRFIP2 protein | CTD | PMID:35688186 | LRRFIP2 | Human | chlordecone | increases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | Chlordecone results in increased expression of LRRFIP2 mRNA | CTD | PMID:29980752 | LRRFIP2 | Human | clofibrate | increases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | Clofibrate results in increased expression of LRRFIP2 mRNA | CTD | PMID:17585979 | LRRFIP2 | Human | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of LRRFIP2 mRNA | CTD | PMID:19376846 | LRRFIP2 | Human | cobalt dichloride | increases expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | cobaltous chloride results in increased expression of LRRFIP2 mRNA | CTD | PMID:24386269 | LRRFIP2 | Human | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of LRRFIP2 mRNA | CTD | PMID:20106945 and PMID:25562108 | LRRFIP2 | Human | Dibutyl phosphate | affects expression | EXP | | 6480464 | di-n-butylphosphoric acid affects the expression of LRRFIP2 mRNA | CTD | PMID:37042841 | LRRFIP2 | Human | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of LRRFIP2 protein | CTD | PMID:26615145 | LRRFIP2 | Human | endosulfan | increases expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of LRRFIP2 mRNA | CTD | PMID:29391264 | LRRFIP2 | Human | ethanol | affects splicing | ISO | Lrrfip2 (Mus musculus) | 6480464 | Ethanol affects the splicing of LRRFIP2 mRNA | CTD | PMID:30319688 | LRRFIP2 | Human | flutamide | increases expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of LRRFIP2 mRNA | CTD | PMID:24136188 | LRRFIP2 | Human | FR900359 | affects phosphorylation | EXP | | 6480464 | FR900359 affects the phosphorylation of LRRFIP2 protein | CTD | PMID:37730182 | LRRFIP2 | Human | fulvestrant | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of LRRFIP2 gene and [bisphenol F co-treated with Fulvestrant] results in decreased methylation of LRRFIP2 gene | CTD | PMID:31601247 | LRRFIP2 | Human | gentamycin | increases expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of LRRFIP2 mRNA | CTD | PMID:33387578 | LRRFIP2 | Human | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of LRRFIP2 protein | CTD | PMID:32959892 | LRRFIP2 | Human | ketoconazole | decreases expression | EXP | | 6480464 | Ketoconazole results in decreased expression of LRRFIP2 mRNA | CTD | PMID:36621641 | LRRFIP2 | Human | lead(0) | affects splicing | EXP | | 6480464 | Lead affects the splicing of LRRFIP2 mRNA | CTD | PMID:28903495 | LRRFIP2 | Human | paracetamol | affects expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LRRFIP2 mRNA | CTD | PMID:17562736 | LRRFIP2 | Human | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of LRRFIP2 mRNA | CTD | PMID:21420995 | LRRFIP2 | Human | pirinixic acid | increases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of LRRFIP2 mRNA | CTD | PMID:18301758 and PMID:18445702 | LRRFIP2 | Human | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of LRRFIP2 mRNA | CTD | PMID:23557933 | LRRFIP2 | Human | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of LRRFIP2 mRNA | CTD | PMID:38568856 | LRRFIP2 | Human | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of LRRFIP2 mRNA | CTD | PMID:31533062 | LRRFIP2 | Human | tamoxifen | affects expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of LRRFIP2 mRNA | CTD | PMID:17555576 | LRRFIP2 | Human | tetrachloromethane | increases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of LRRFIP2 mRNA | CTD | PMID:27339419 and PMID:31919559 | LRRFIP2 | Human | tetrachloromethane | multiple interactions | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of LRRFIP2 mRNA] | CTD | PMID:31150632 | LRRFIP2 | Human | tetrachloromethane | increases expression | ISO | Lrrfip2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of LRRFIP2 mRNA | CTD | PMID:31150632 | LRRFIP2 | Human | thiram | increases expression | EXP | | 6480464 | Thiram results in increased expression of LRRFIP2 mRNA | CTD | PMID:38568856 | LRRFIP2 | Human | titanium dioxide | decreases methylation | ISO | Lrrfip2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of LRRFIP2 promoter | CTD | PMID:35295148 | LRRFIP2 | Human | titanium dioxide | increases methylation | ISO | Lrrfip2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of LRRFIP2 promoter | CTD | PMID:35295148 | LRRFIP2 | Human | triphenyl phosphate | affects expression | EXP | | 6480464 | triphenyl phosphate affects the expression of LRRFIP2 mRNA | CTD | PMID:37042841 | LRRFIP2 | Human | triptonide | increases expression | ISO | Lrrfip2 (Mus musculus) | 6480464 | triptonide results in increased expression of LRRFIP2 mRNA | CTD | PMID:33045310 | LRRFIP2 | Human | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of LRRFIP2 mRNA | CTD | PMID:23179753 | |