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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of pattern recognition receptor signaling pathway
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Accession:GO:0062208 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.


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positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO
IEA
IBA		 (PMID:31649195)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:31649195 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:69,771,890...69,799,921 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp2 guanylate binding protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:25774715), (PMID:25774716)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25774715 PMID:25774716 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO
IEA		 (PMID:25774715), (PMID:25774716)
GO_REF:0000107		 RGD
Ensembl		 PMID:25774715 PMID:25774716 GO_REF:0000107 NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase involved_in ISO
IEA		 (PMID:25704810)
GO_REF:0000107		 RGD
Ensembl		 PMID:25704810 GO_REF:0000107 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) RGD PMID:37832545 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:37916870)		 Ensembl
RGD		 PMID:37916870 GO_REF:0000107 NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632 		JBrowse link
G Rnf39 ring finger protein 39 involved_in ISO (PMID:39255680) RGD PMID:39255680 NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,604,794...1,610,283 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 involved_in ISO
IEA		 (PMID:36745868)
GO_REF:0000107		 RGD
Ensembl		 PMID:36745868 GO_REF:0000107 NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,584,411...11,601,972 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 involved_in ISO
IEA		 (PMID:37832545)
GO_REF:0000107		 RGD
Ensembl		 PMID:37832545 GO_REF:0000107 NCBI chr 7:113,556,157...113,587,351
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Zdhhc9 zinc finger DHHC-type palmitoyltransferase 9 involved_in ISO
IEA		 (PMID:37802025)
GO_REF:0000107		 RGD
Ensembl		 PMID:37802025 GO_REF:0000107 NCBI chr  X:132,230,243...132,266,139
Ensembl chr  X:127,352,345...127,388,245 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO
IEA		 (PMID:22328336)
GO_REF:0000107		 RGD
Ensembl		 PMID:22328336 GO_REF:0000107 NCBI chr14:18,007,342...18,145,980
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 involved_in ISO (PMID:21791617) RGD PMID:21791617 NCBI chr16:33,087,940...33,208,843
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IEA		 (PMID:20080593)
GO_REF:0000107		 RGD
Ensembl		 PMID:20080593 GO_REF:0000107 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:20368735) RGD PMID:20368735 NCBI chr 1:168,563,281...168,567,056
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
positive regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc134 coiled-coil domain containing 134 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:38670073)		 UniProt
Ensembl
RGD		 PMID:38670073 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:115,526,537...115,539,155
Ensembl chr 7:113,644,639...113,659,050 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO
IEA		 (PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,844,616...2,861,964 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23246432)
(PMID:28943315)		 UniProt
RGD		 PMID:23246432 PMID:28943315 GO_REF:0000024 NCBI chr 9:2,073,927...2,076,469
Ensembl chr 9:1,986,575...1,991,080 		JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO
IEA		 (PMID:34554188)
GO_REF:0000107		 RGD
Ensembl		 PMID:34554188 GO_REF:0000107 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:26173909) RGD PMID:26173909 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cd36 CD36 molecule involved_in ISS
ISO		 GO_REF:0000024
(PMID:23812099)		 UniProt
RGD		 PMID:23812099 GO_REF:0000024 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd36l1 CD36 molecule like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:18,316,806...18,357,863
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO
IEA		 (PMID:31511697)
GO_REF:0000107		 RGD
Ensembl		 PMID:31511697 GO_REF:0000107 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO
IEA		 (PMID:23871209)
GO_REF:0000107		 RGD
Ensembl		 PMID:23871209 GO_REF:0000107 NCBI chr10:56,206,680...56,223,189
Ensembl chr10:55,705,756...55,724,567 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO
IEA		 (PMID:22461501)
GO_REF:0000107		 RGD
Ensembl		 PMID:22461501 GO_REF:0000107 NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Kcnk6 potassium two pore domain channel subfamily K member 6 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:93,652,888...93,661,419
Ensembl chr 1:84,525,590...84,534,677 		JBrowse link
G Lats1 large tumor suppressor kinase 1 involved_in ISO
IEA		 (PMID:39173637)
GO_REF:0000107		 RGD
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Lats2 large tumor suppressor kinase 2 involved_in ISO
IEA		 (PMID:39173637)
GO_REF:0000107		 RGD
Ensembl		 PMID:39173637 GO_REF:0000107 NCBI chr15:35,940,632...35,992,225
Ensembl chr15:31,825,092...31,877,220 		JBrowse link
G LOC134486712 platelet glycoprotein 4-like involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:18,372,301...18,408,431 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:28943315)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:28943315 GO_REF:0000024 GO_REF:0000107 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:37575012)		 Ensembl
RGD		 PMID:37575012 GO_REF:0000107 NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:234,931,271...234,952,632 		JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO
IEA		 (PMID:28656979)
GO_REF:0000107		 RGD
Ensembl		 PMID:28656979 GO_REF:0000107 NCBI chr 1:88,203,352...88,239,858
Ensembl chr 1:79,068,904...79,108,556 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:23582325) RGD PMID:23582325 NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mir21 microRNA 21 IDA RGD PMID:29084974 RGD:41404715 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:33718825)		 UniProt
Ensembl
RGD		 PMID:33718825 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:31189953), (PMID:36442502), (PMID:39173637)
(PMID:26642356), (PMID:26814970)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 PMID:39173637 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:52,573,730...52,700,869
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29958799)		 UniProt
RGD		 PMID:29958799 GO_REF:0000024 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within ISO (PMID:32514138) RGD PMID:32514138 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:28465465)		 UniProt
RGD		 PMID:28465465 GO_REF:0000024 NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28716882)		 UniProt
Ensembl
RGD		 PMID:28716882 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:27043286) RGD PMID:27043286 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (PMID:31836654) RGD PMID:31836654 NCBI chr 4:64,894,663...64,904,495 JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23812099)		 UniProt
Ensembl
RGD		 PMID:23812099 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA		 (PMID:23812099)
GO_REF:0000107		 RGD
Ensembl		 PMID:23812099 GO_REF:0000107 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO
IEA		 (PMID:28094437)
GO_REF:0000107		 RGD
Ensembl		 PMID:28094437 GO_REF:0000107 NCBI chr 3:134,465,469...134,488,859
Ensembl chr 3:114,011,702...114,035,476 		JBrowse link
G Zdhhc1 zinc finger, DHHC-type containing 1 involved_in ISO (PMID:39173637) RGD PMID:39173637 NCBI chr19:50,260,445...50,285,634
Ensembl chr19:33,350,533...33,375,616 		JBrowse link
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO
IEA		 (PMID:38092000)
GO_REF:0000107		 RGD
Ensembl		 PMID:38092000 GO_REF:0000107 NCBI chr 3:90,178,734...90,206,889
Ensembl chr 3:69,771,890...69,799,921 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19570976), (PMID:21277849)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19570976 PMID:21277849 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Slc46a2 solute carrier family 46, member 2 involved_in ISO
IEA		 (PMID:28539433)
GO_REF:0000107		 RGD
Ensembl		 PMID:28539433 GO_REF:0000107 NCBI chr 5:79,594,003...79,603,074
Ensembl chr 5:74,800,226...74,808,128 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO
IEA		 (PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Nagk N-acetylglucosamine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:36002575)		 UniProt
Ensembl
RGD		 PMID:36002575 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:117,838,761...117,846,304
Ensembl chr 4:116,281,328...116,313,137 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) RGD PMID:23892723 NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24695226)		 UniProt
Ensembl
RGD		 PMID:24695226 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:216,906,836...216,932,046
Ensembl chr 1:207,492,365...207,507,157 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:24695226)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24695226 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO
IEA		 (PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO
IEA		 (PMID:22328336)
GO_REF:0000107		 RGD
Ensembl		 PMID:22328336 GO_REF:0000107 NCBI chr14:18,007,342...18,145,980
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 involved_in ISO (PMID:21791617) RGD PMID:21791617 NCBI chr16:33,087,940...33,208,843
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IEA		 (PMID:20080593)
GO_REF:0000107		 RGD
Ensembl		 PMID:20080593 GO_REF:0000107 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like involved_in ISO (PMID:25925578) RGD PMID:25925578 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Pum1 pumilio RNA-binding family member 1 involved_in ISO
IEA		 (PMID:25340845)
GO_REF:0000107		 RGD
Ensembl		 PMID:25340845 GO_REF:0000107 NCBI chr 5:148,120,712...148,238,468
Ensembl chr 5:142,837,127...142,954,039 		JBrowse link
G Pum2 pumilio RNA-binding family member 2 involved_in ISO
IEA		 (PMID:25340845)
GO_REF:0000107		 RGD
Ensembl		 PMID:25340845 GO_REF:0000107 NCBI chr 6:37,182,130...37,262,223
Ensembl chr 6:31,462,872...31,542,976 		JBrowse link
G Trim15 tripartite motif containing 15 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr20:1,703,723...1,715,465
Ensembl chr20:1,700,905...1,710,249 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in ISO
IEA		 (PMID:24399297)
GO_REF:0000107		 RGD
Ensembl		 PMID:24399297 GO_REF:0000107 NCBI chr 7:60,643,611...60,805,137
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:20368735) RGD PMID:20368735 NCBI chr 1:168,563,281...168,567,056
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,979,055...68,029,353
Ensembl chr 4:67,012,185...67,062,428 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IBA
IEA		 (PMID:30193849)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:30193849 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:161,332,760...161,335,591
Ensembl chr 3:140,872,460...140,882,408 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (PMID:25848864) RGD PMID:25848864 NCBI chr 9:20,216,569...20,241,476
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain involved_in ISO
IEA		 (PMID:22423966)
GO_REF:0000107		 RGD
Ensembl		 PMID:22423966 GO_REF:0000107 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA		 (PMID:19865078)
GO_REF:0000107		 RGD
Ensembl		 PMID:19865078 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) RGD PMID:16267105 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO
IEA		 (PMID:26599367), (PMID:28471450)
GO_REF:0000107		 RGD
Ensembl		 PMID:26599367 PMID:28471450 GO_REF:0000107 NCBI chr16:63,248,833...63,336,441
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO
IEA
ISS		 (PMID:28471450)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28471450 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:111,403,624...111,453,703
Ensembl chr 9:103,956,678...104,006,783 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr1 toll-like receptor 1 involved_in ISO
IEA		 ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949)
GO_REF:0000107		 RGD
Ensembl		 PMID:22198949 GO_REF:0000107 NCBI chr14:43,737,761...43,750,389
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:25204797)
GO_REF:0000107		 RGD
Ensembl		 PMID:25204797 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA		 (PMID:19865078)
GO_REF:0000107		 RGD
Ensembl		 PMID:19865078 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Flot1 flotillin 1 involved_in ISO
IEA		 (PMID:25204797)
GO_REF:0000107		 RGD
Ensembl		 PMID:25204797 GO_REF:0000107 NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA		 MGI:4361448 (PMID:19734906)
GO_REF:0000107		 RGD
Ensembl		 PMID:19734906 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:17322885) RGD PMID:17322885 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Trim3 tripartite motif-containing 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:32878999)		 Ensembl
RGD		 PMID:32878999 GO_REF:0000107 NCBI chr 1:169,362,751...169,385,430
Ensembl chr 1:159,944,908...159,973,600 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IEA
IBA		 (PMID:25736436)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:88,459,613...88,541,215
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24380872)		 UniProt
Ensembl
RGD		 PMID:24380872 GO_REF:0000024 GO_REF:0000107 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IEA		 (PMID:18622013)
GO_REF:0000107		 RGD
Ensembl		 PMID:18622013 GO_REF:0000107 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:16267105) RGD PMID:16267105 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ifi35 interferon-induced protein 35 involved_in ISO
IEA		 (PMID:29038465)
GO_REF:0000107		 RGD
Ensembl		 PMID:29038465 GO_REF:0000107 NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA		 (PMID:11528597)
GO_REF:0000107		 RGD
Ensembl		 PMID:11528597 GO_REF:0000107 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25860173)		 UniProt
RGD		 PMID:25860173 GO_REF:0000024 NCBI chr17:15,659,208...15,668,115
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA		 (PMID:18511497)
GO_REF:0000107		 RGD
Ensembl		 PMID:18511497 GO_REF:0000107 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA		 MGI:4361448 (PMID:19734906)
GO_REF:0000107		 RGD
Ensembl		 PMID:19734906 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567)		 RGD PMID:19412184 PMID:22685567 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IEA
IBA		 (PMID:25736436)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:25736436 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:88,459,613...88,541,215
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO
IEA		 (PMID:28593998)
GO_REF:0000107		 RGD
Ensembl		 PMID:28593998 GO_REF:0000107 NCBI chr19:39,496,414...39,581,600
Ensembl chr19:39,496,527...39,580,969 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21435586)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21435586 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:21045126), (PMID:25238095)
GO_REF:0000024
(PMID:25238095), (PMID:32433612)		 Ensembl
RGD
UniProt		 PMID:21045126 PMID:25238095 PMID:32433612 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO
IEA		 (PMID:32433612)
GO_REF:0000107		 RGD
Ensembl		 PMID:32433612 GO_REF:0000107 NCBI chr  X:54,354,755...54,373,930
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO
IBA		 (PMID:25848864)
GO_REF:0000033		 RGD
GO_Central		 PMID:25848864 GO_REF:0000033 NCBI chr 9:20,216,569...20,241,476
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:32433612)		 Ensembl
UniProt
RGD		 PMID:32433612 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO
IEA		 (PMID:32433612)
GO_REF:0000107		 RGD
Ensembl		 PMID:32433612 GO_REF:0000107 NCBI chr  X:54,354,755...54,373,930
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21435586)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21435586 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:25917084)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25917084 GO_REF:0000024 GO_REF:0000107 NCBI chr14:107,651,001...107,698,610
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO
ISS
IEA		 (PMID:25238095)
(PMID:21045126), (PMID:21277849), (PMID:25238095)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:21045126 PMID:21277849 PMID:25238095 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA		 (PMID:18931679)
GO_REF:0000107		 RGD
Ensembl		 PMID:18931679 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (PMID:25848864) RGD PMID:25848864 NCBI chr 9:20,216,569...20,241,476
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO
IEA		 (PMID:38169466)
GO_REF:0000107		 RGD
Ensembl		 PMID:38169466 GO_REF:0000107 NCBI chr 8:131,602,663...131,650,998
Ensembl chr 8:122,715,111...122,773,529 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdi1 GDP dissociation inhibitor 1 involved_in ISO
IEA		 (PMID:35343654)
GO_REF:0000107		 RGD
Ensembl		 PMID:35343654 GO_REF:0000107 NCBI chr  X:157,238,900...157,245,562
Ensembl chr  X:152,087,444...152,094,272 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 involved_in ISO
IEA		 (PMID:11584270)
GO_REF:0000107		 RGD
Ensembl		 PMID:11584270 GO_REF:0000107 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 involved_in ISO (PMID:16449650) RGD PMID:16449650 NCBI chr12:24,694,364...24,709,354
Ensembl chr12:19,057,587...19,068,577 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) RGD PMID:20728433 NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        positive regulation of signal transduction 1768
          positive regulation of pattern recognition receptor signaling pathway 87
            positive regulation of MDA-5 signaling pathway 4
            positive regulation of RIG-I signaling pathway 12
            positive regulation of cGAS/STING signaling pathway 7
            positive regulation of inflammasome-mediated signaling pathway + 32
            positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway + 8
            positive regulation of peptidoglycan recognition protein signaling pathway 0
            positive regulation of toll-like receptor 1 signaling pathway 0
            positive regulation of toll-like receptor 10 signaling pathway 0
            positive regulation of toll-like receptor 11 signaling pathway 0
            positive regulation of toll-like receptor 12 signaling pathway 0
            positive regulation of toll-like receptor 13 signaling pathway 1
            positive regulation of toll-like receptor 15 signaling pathway 0
            positive regulation of toll-like receptor 2 signaling pathway 7
            positive regulation of toll-like receptor 3 signaling pathway 8
            positive regulation of toll-like receptor 4 signaling pathway 14
            positive regulation of toll-like receptor 5 signaling pathway 0
            positive regulation of toll-like receptor 6 signaling pathway 0
            positive regulation of toll-like receptor 7 signaling pathway 6
            positive regulation of toll-like receptor 8 signaling pathway 3
            positive regulation of toll-like receptor 9 signaling pathway + 8
            positive regulation of toll-like receptor signaling pathway + 5
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to biotic stimulus 1943
        response to external biotic stimulus 1894
          response to other organism 1890
            defense response to other organism 1336
              defense response to symbiont 1112
                innate immune response 1025
                  regulation of innate immune response 491
                    positive regulation of innate immune response 401
                      activation of innate immune response 329
                        innate immune response-activating signaling pathway 301
                          pattern recognition receptor signaling pathway 290
                            regulation of pattern recognition receptor signaling pathway 192
                              positive regulation of pattern recognition receptor signaling pathway 87
                                positive regulation of MDA-5 signaling pathway 4
                                positive regulation of RIG-I signaling pathway 12
                                positive regulation of cGAS/STING signaling pathway 7
                                positive regulation of inflammasome-mediated signaling pathway + 32
                                positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway + 8
                                positive regulation of peptidoglycan recognition protein signaling pathway 0
                                positive regulation of toll-like receptor 1 signaling pathway 0
                                positive regulation of toll-like receptor 10 signaling pathway 0
                                positive regulation of toll-like receptor 11 signaling pathway 0
                                positive regulation of toll-like receptor 12 signaling pathway 0
                                positive regulation of toll-like receptor 13 signaling pathway 1
                                positive regulation of toll-like receptor 15 signaling pathway 0
                                positive regulation of toll-like receptor 2 signaling pathway 7
                                positive regulation of toll-like receptor 3 signaling pathway 8
                                positive regulation of toll-like receptor 4 signaling pathway 14
                                positive regulation of toll-like receptor 5 signaling pathway 0
                                positive regulation of toll-like receptor 6 signaling pathway 0
                                positive regulation of toll-like receptor 7 signaling pathway 6
                                positive regulation of toll-like receptor 8 signaling pathway 3
                                positive regulation of toll-like receptor 9 signaling pathway + 8
                                positive regulation of toll-like receptor signaling pathway + 5
paths to the root