AC097637.1 (novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: AC097637.1 (novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein) Homo sapiens
Analyze
Symbol: AC097637.1
Name: novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein
RGD ID: 16550817
Description: ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN activation of innate immune response (inferred); inflammatory response (inferred); innate immune response (inferred); FOUND IN cytoplasm (inferred); endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred)
Type: protein-coding
Latest Assembly: GRCh38.p14 Ensembl - Human Genome Assembly GRCh38 Ensembl
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p14 Ensembl352,221,081 - 52,231,190 (-)EnsemblGRCh38hg38GRCh38
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:649
Count of miRNA genes:462
Interacting mature miRNAs:497
Transcripts:ENST00000478201, ENST00000494383
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system integumental system nervous system renal system reproductive system respiratory system
High
Medium
Low
Below cutoff 1 1 10 2 3 1 2 3

Sequence

Nucleotide Sequences

Reference Sequences
RefSeq Acc Id: ENST00000478201   ⟹   ENSP00000419980
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl352,223,920 - 52,229,773 (-)Ensembl
RefSeq Acc Id: ENST00000494383   ⟹   ENSP00000417517
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl352,221,081 - 52,231,190 (-)Ensembl
Protein Sequences
Ensembl Protein ENSP00000417517.1
  ENSP00000419980.1
Reference Protein Sequences
RefSeq Acc Id: ENSP00000419980   ⟸   ENST00000478201
RefSeq Acc Id: ENSP00000417517   ⟸   ENST00000494383
Protein Domains
ADF-H   TIR


Additional Information

Database Acc Id Source(s)
COSMIC AC097637.1 COSMIC
Ensembl Genes ENSG00000173366 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENST00000478201.1 UniProtKB/TrEMBL
  ENST00000494383.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/TrEMBL
  3.40.50.10140 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
GTEx ENSG00000173366 GTEx
Human Proteome Map AC097637.1 Human Proteome Map
InterPro ADF-H UniProtKB/TrEMBL
  ADF-H/Gelsolin-like_dom_sf UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_12 UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  TIR_dom UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
  Twinfilin UniProtKB/TrEMBL
PANTHER PTHR13759 UniProtKB/TrEMBL
  PTHR47410:SF3 UniProtKB/TrEMBL
  TOLL-LIKE RECEPTOR 7-RELATED UniProtKB/TrEMBL
  TWINFILIN-2 UniProtKB/TrEMBL
Pfam Cofilin_ADF UniProtKB/TrEMBL
  LRR_12 UniProtKB/TrEMBL
  LRR_6 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE ADF_H UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
SMART ADF UniProtKB/TrEMBL
  LRR_BAC UniProtKB/TrEMBL
  LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/TrEMBL
  L domain-like UniProtKB/TrEMBL
  SSF52200 UniProtKB/TrEMBL
UniProt H0Y858_HUMAN UniProtKB/TrEMBL
  H7C5I2_HUMAN UniProtKB/TrEMBL