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Gene: SCARA3 (scavenger receptor class A member 3) Homo sapiens
Symbol: SCARA3
Name: scavenger receptor class A member 3
Description: This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APC7; cellular stress response gene protein; cellular stress response protein; CSR; CSR1; macrophage scavenger receptor-like 1; MSLR1; MSRL1; scavenger receptor class A, member 3
Mus musculus (house mouse) : Scara3 (scavenger receptor class A, member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Scara3 (scavenger receptor class A, member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scara3 (scavenger receptor class A member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SCARA3 (scavenger receptor class A member 3)
Canis lupus familiaris (dog) : SCARA3 (scavenger receptor class A member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scara3 (scavenger receptor class A member 3)
Sus scrofa (pig) : SCARA3 (scavenger receptor class A member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38827,633,665 - 27,736,594 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37827,491,100 - 27,534,286 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36827,547,496 - 27,590,205 (+)NCBINCBI36hg18NCBI36
Build 34827,547,495 - 27,590,205NCBI
Celera826,451,665 - 26,494,373 (+)NCBI
Cytogenetic Map8p21.1NCBI
HuRef826,036,621 - 26,079,326 (+)NCBIHuRef
CHM1_1827,693,466 - 27,736,166 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SCARA3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319520
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.