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Pathways
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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
innate immune response activating cell surface receptor signaling pathway +   
pattern recognition receptor signaling pathway +   
The series of molecular signals initiated by a ligand binding to a pattern recognition receptor (PRR), and ending with the regulation of a downstream cellular process, e.g. transcription. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.

Synonyms
Exact Synonyms: PRR signaling pathway ;   pathogen receptor signaling pathway ;   pathogen receptor signalling pathway
Definition Sources: GOC:add, GOC:ar, ISBN:0781735149, PMID:15199967

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