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Gene: LGR4 (leucine rich repeat containing G protein-coupled receptor 4) Homo sapiens
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Symbol: LGR4
Name: leucine rich repeat containing G protein-coupled receptor 4
Description: Exhibits transmembrane signaling receptor activity. Involved in positive regulation of canonical Wnt signaling pathway. Localizes to integral component of plasma membrane. Implicated in osteoporosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BNMD17; G protein-coupled receptor 48; G-protein coupled receptor 48; G-protein-coupled receptor 48; GPR48; leucine-rich repeat containing G protein-coupled receptor 4; leucine-rich repeat-containing G protein-coupled receptor 4; leucine-rich repeat-containing G-protein coupled receptor 4
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1127,365,961 - 27,472,790 (-)EnsemblGRCh38hg38GRCh38
GRCh381127,365,961 - 27,472,790 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371127,387,508 - 27,494,338 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361127,344,084 - 27,450,910 (-)NCBINCBI36hg18NCBI36
Celera1127,532,862 - 27,640,072 (-)NCBI
Cytogenetic Map11p14.1NCBI
HuRef1127,084,852 - 27,193,084 (-)NCBIHuRef
CHM1_11127,386,916 - 27,493,708 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LGR4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605061
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.