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Gene: TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1) Homo sapiens
Symbol: TAB1
Name: TGF-beta activated kinase 1 (MAP3K7) binding protein 1
Description: Predicted to have magnesium-dependent protein serine/threonine phosphatase activity and mitogen-activated protein kinase p38 binding activity. Predicted to be involved in several processes, including immune response-regulating signaling pathway; intracellular signal transduction; and positive regulation of NF-kappaB transcription factor activity. Localizes to the cytosol and nuclear speck.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 3'-Tab1; MAP3K7IP1; MGC57664; mitogen-activated protein kinase kinase kinase 7 interacting protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TAK1-binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; transforming growth factor beta-activated kinase-binding protein 1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382239,399,780 - 39,437,132 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372239,795,759 - 39,833,132 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,125,705 - 38,163,078 (+)NCBINCBI36hg18NCBI36
Build 342238,120,258 - 38,157,632NCBI
Celera2223,597,809 - 23,635,185 (+)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2222,760,425 - 22,797,733 (+)NCBIHuRef
CHM1_12239,754,498 - 39,791,875 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TAB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314707
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.