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Gene: USP27X (ubiquitin specific peptidase 27 X-linked) Homo sapiens
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Symbol: USP27X
Name: ubiquitin specific peptidase 27 X-linked
Description: Predicted to have Lys48-specific deubiquitinase activity; Lys63-specific deubiquitinase activity; and thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in positive regulation of apoptotic process; protein deubiquitination; and protein stabilization. Predicted to localize to the cytosol and nucleus. Implicated in non-syndromic X-linked intellectual disability.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deubiquitinating enzyme 27; MRX105; ubiquitin carboxyl-terminal hydrolase 22-like; ubiquitin carboxyl-terminal hydrolase 27; ubiquitin specific peptidase 27, X-linked; ubiquitin specific protease 27, X chromosome; ubiquitin thioesterase 27; ubiquitin thiolesterase 27; ubiquitin-specific-processing protease 27; USP22L; USP27; X-linked ubiquitin carboxyl-terminal hydrolase 27
Orthologs:
Mus musculus (house mouse) : Usp27x (ubiquitin specific peptidase 27, X chromosome)  MGI  Alliance
Rattus norvegicus (Norway rat) : Usp27x (ubiquitin specific peptidase 27, X-linked)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp27x (ubiquitin specific peptidase 27 X-linked)
Pan paniscus (bonobo/pygmy chimpanzee) : USP27X (ubiquitin specific peptidase 27, X-linked)
Canis lupus familiaris (dog) : USP27X (ubiquitin specific peptidase 27 X-linked)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp27x (ubiquitin specific peptidase 27 X-linked)
Sus scrofa (pig) : USP27X (ubiquitin specific peptidase 27 X-linked)
Chlorocebus sabaeus (green monkey) : USP27X (ubiquitin specific peptidase 27 X-linked)
Heterocephalus glaber (naked mole-rat) : Usp27x (ubiquitin specific peptidase 27 X-linked)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX49,879,484 - 49,882,558 (+)Ensembl
GRCh38X49,879,484 - 49,882,558 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,644,470 - 49,647,169 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X49,530,949 - 49,533,210 (+)NCBINCBI36hg18NCBI36
CeleraX53,713,777 - 53,716,476 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX47,113,635 - 47,116,334 (+)NCBIHuRef
CHM1_1X49,724,245 - 49,726,944 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on USP27X
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350698
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.