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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of innate immune response
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Accession:GO:0045088 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.


show annotations for term's descendants           Sort by:
regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (MGI:6212700|PMID:29336888) RGD PMID:29336888 MGI:6212700 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6270783|PMID:27219021) RGD PMID:27219021 MGI:6270783 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6270783|PMID:27219021) RGD PMID:27219021 MGI:6270783 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Casp8 caspase 8 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6472603|PMID:32971525)		 UniProt
RGD		 PMID:32971525 GO_REF:0000024 MGI:6472603 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (PMID:18411269) RGD PMID:18411269 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (MGI:3051749|PMID:15306813) RGD PMID:15306813 MGI:3051749 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5294498|PMID:21746961)		 UniProt
RGD		 PMID:21746961 GO_REF:0000024 MGI:5294498 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Lrp8 LDL receptor related protein 8 involved_in ISO (MGI:6212700|PMID:29336888) RGD PMID:29336888 MGI:6212700 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352 		JBrowse link
G Myo1f myosin IF acts_upstream_of_or_within ISO MGI:3664779 (MGI:3664353|PMID:17023661) RGD PMID:17023661 MGI:3664353 NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911 		JBrowse link
G N4bp1 Nedd4 binding protein 1 involved_in ISO (MGI:6472603|PMID:32971525) RGD PMID:32971525 MGI:6472603 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO
ISS		 (MGI:3622037|PMID:16585964)
GO_REF:0000024		 RGD
UniProt		 PMID:16585964 GO_REF:0000024 MGI:3622037 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Rnf135 ring finger protein 135 involved_in ISO
IBA
ISS		 (PMID:19017631)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:19017631 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:65,170,560...65,189,791
Ensembl chr10:65,170,560...65,262,804 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO
IBA		 (PMID:19525956), (PMID:29670289)
PMID:21873635		 RGD PMID:19525956 PMID:29670289 PMID:21873635 RGD:13792537 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Serpinb1a serpin family B member 1A involved_in ISO (MGI:3760197|PMID:17664292) RGD PMID:17664292 MGI:3760197 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISO (PMID:16289032) RGD PMID:16289032 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6275756|PMID:30548312) RGD PMID:30548312 MGI:6275756 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (MGI:4848004|PMID:20871604), (MGI:5787754|PMID:26320659) RGD PMID:20871604 PMID:26320659 MGI:4848004 MGI:5787754 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
activation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO
IBA		 (PMID:19158675), (PMID:19158676), (PMID:19158679)
PMID:21873635
(MGI:3839523|PMID:19158676)		 RGD PMID:19158675 PMID:19158676 PMID:19158679 PMID:21873635 MGI:3839523, RGD:13792537 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Casp6 caspase 6 involved_in ISO
IEA
ISS		 (PMID:32298652)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:32298652 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in IBA
ISO		 PMID:21873635
(PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:29426904), (PMID:30007416), (PMID:32817552), (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35438208)
(MGI:5487472|PMID:23258413), (MGI:5505711|PMID:23929945), (MGI:5908326|PMID:24077100), (MGI:6119245|PMID:29426904), (MGI:6754862|PMID:32911480), (MGI:6810288|PMID:32911481), (MGI:6828894|PMID:32913000)		 RGD PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More... MGI:5487472 MGI:5505711 MGI:5908326 MGI:6119245 MGI:6754862 MGI:6810288 MGI:6828894, RGD:13792537 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G ENSRNOG00000069878 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr13:85,977,035...85,994,718 JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (MGI:5571540|PMID:24739961) RGD PMID:24739961 MGI:5571540 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Gbp2 guanylate binding protein 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5571540|PMID:24739961)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24739961 GO_REF:0000024 GO_REF:0000107 MGI:5571540 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp4 guanylate binding protein 4 involved_in ISO (MGI:5571540|PMID:24739961) RGD PMID:24739961 MGI:5571540 NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (MGI:5571540|PMID:24739961) RGD PMID:24739961 MGI:5571540 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Gbp7 guanylate binding protein 7 involved_in ISO (MGI:5571540|PMID:24739961) RGD PMID:24739961 MGI:5571540 NCBI chr 2:231,275,521...231,297,289
Ensembl chr 2:231,275,640...231,297,278 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:24971542) RGD PMID:24971542 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO
ISS		 (PMID:20628368)
GO_REF:0000024		 RGD
UniProt		 PMID:20628368 GO_REF:0000024 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Ifi214 interferon activated gene 214 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:85,940,028...85,951,004
Ensembl chr13:85,940,078...85,951,004 		JBrowse link
G LOC102556096 pyrin domain-containing protein 3-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:85,911,915...85,929,491
Ensembl chr13:85,912,044...85,929,007 		JBrowse link
G Matr3 matrin 3 involved_in ISO
IEA		 (PMID:28712728)
GO_REF:0000107		 RGD
Ensembl		 PMID:28712728 GO_REF:0000107 NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO
ISS		 (PMID:18818105), (PMID:20628368)
GO_REF:0000024		 RGD
UniProt		 PMID:18818105 PMID:20628368 GO_REF:0000024 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3662990|PMID:16648852)		 UniProt
RGD		 PMID:16648852 GO_REF:0000024 MGI:3662990 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 involved_in ISO (PMID:22672233) RGD PMID:22672233 NCBI chr 1:162,922,806...162,930,363
Ensembl chr 1:162,922,806...162,930,363 		JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISO
ISS		 (PMID:26046437)
GO_REF:0000024		 RGD
UniProt		 PMID:26046437 GO_REF:0000024 NCBI chr  X:14,603,516...14,608,091
Ensembl chr  X:14,603,539...14,608,087 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Pspc1 paraspeckle component 1 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:21575908)
(MGI:3839029|PMID:19158675)		 RGD PMID:19158675 PMID:21575908 MGI:3839029 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665 		JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (PMID:22783022) RGD PMID:22783022 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IBA		 (MGI:5487473|PMID:23258412), (MGI:5487515|PMID:21947006), (MGI:6827194|PMID:23910378)
(PMID:18818105), (PMID:23910378)
PMID:21873635		 RGD PMID:18818105 PMID:21947006 PMID:23258412 PMID:23910378 PMID:21873635 MGI:5487473 MGI:5487515 MGI:6827194, RGD:13792537 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 acts_upstream_of_or_within
involved_in		 ISO MGI:3046789 (MGI:3530402|PMID:15661922)
(PMID:25636800)		 RGD PMID:15661922 PMID:25636800 MGI:3530402 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO MGI:1860885 (MGI:3530402|PMID:15661922) RGD PMID:15661922 MGI:3530402 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (MGI:5887188|PMID:25686612) RGD PMID:25686612 MGI:5887188 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:20628368)		 Ensembl
UniProt
RGD		 PMID:20628368 GO_REF:0000024 GO_REF:0000107 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202 		JBrowse link
G Trim5 tripartite motif-containing 5 involved_in ISO (PMID:21512573) RGD PMID:21512573 NCBI chr 1:158,720,407...158,737,393
Ensembl chr 1:158,720,410...158,814,012 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6434626|PMID:32296175), (MGI:6436412|PMID:32200799), (MGI:6453154|PMID:32350114), (MGI:6490907|PMID:33109609)		 UniProt
RGD		 PMID:32200799 PMID:32296175 PMID:32350114 PMID:33109609 GO_REF:0000024 MGI:6434626 MGI:6436412 MGI:6453154 MGI:6490907 NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IBA		 (PMID:30135424), (PMID:30193849)
PMID:21873635
(MGI:6209107|PMID:30135424), (MGI:6271678|PMID:30193849)		 RGD PMID:30135424 PMID:30193849 PMID:21873635 MGI:6209107 MGI:6271678, RGD:13792537 NCBI chr 3:140,872,460...140,875,292
Ensembl chr 3:140,872,460...140,882,408 		JBrowse link
G Znfx1 zinc finger, NFX1-type containing 1 involved_in ISO (MGI:6384069|PMID:31685995) RGD PMID:31685995 MGI:6384069 NCBI chr 3:155,764,073...155,791,777
Ensembl chr 3:155,764,980...155,821,242 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:15294986) RGD PMID:15294986 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Clec7a C-type lectin domain containing 7A acts_upstream_of_or_within ISO (MGI:3042099|PMID:12719478) RGD PMID:12719478 MGI:3042099 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Fcna ficolin A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105 		JBrowse link
G Fcnb ficolin B involved_in ISO (PMID:21037097) RGD PMID:21037097 NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO
ISS		 (PMID:21037097)
GO_REF:0000024		 RGD
UniProt		 PMID:21037097 GO_REF:0000024 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA		 (PMID:15294986)
GO_REF:0000107		 RGD
Ensembl		 PMID:15294986 GO_REF:0000107 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:22966085) RGD PMID:22966085 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675 (MGI:3042099|PMID:12719478) RGD PMID:12719478 MGI:3042099 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in IEA
ISO		 GO_REF:0000107
(PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35322803), (PMID:35438208), (PMID:35460603)		 Ensembl
RGD		 PMID:32911482 PMID:32912999 PMID:33542149 PMID:35322803 PMID:35438208 More... GO_REF:0000107 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25636800), (PMID:30842659), (PMID:30842662)		 Ensembl
RGD		 PMID:25636800 PMID:30842659 PMID:30842662 GO_REF:0000107 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpk1 alpha-kinase 1 involved_in ISO
IBA		 (PMID:28222186), (PMID:28877472), (PMID:30111836)
PMID:21873635
(MGI:6196443|PMID:30111836)		 RGD PMID:28222186 PMID:28877472 PMID:30111836 PMID:21873635 MGI:6196443, RGD:13792537 NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23258413) RGD PMID:23258413 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (PMID:19211564) RGD PMID:19211564 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Ipo5 importin 5 involved_in ISO (PMID:31340999) RGD PMID:31340999 NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:8524823) RGD PMID:8524823 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:21931555) RGD PMID:21931555 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16125763), (PMID:20451243) RGD PMID:16125763 PMID:20451243 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (PMID:19576794) RGD PMID:19576794 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378) RGD PMID:23910378 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (PMID:29441066) RGD PMID:29441066 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain involved_in ISO
IBA
ISS		 (PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23015697)		 Ensembl
RGD		 PMID:23015697 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trim25 tripartite motif-containing 25 involved_in ISO (PMID:17392790) RGD PMID:17392790 NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISO (PMID:22607805) RGD PMID:22607805 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589 		JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll-like receptor 4 IMP RGD PMID:19226379 RGD:2312509 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO
IBA		 (PMID:17600090), (PMID:19211564), (PMID:33727702)
PMID:21873635		 RGD PMID:17600090 PMID:19211564 PMID:33727702 PMID:21873635 RGD:13792537 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (MGI:3836337|PMID:19265123) RGD PMID:19265123 MGI:3836337 NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255 		JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) RGD PMID:14660645 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) RGD PMID:16148103 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1346060|MGI:2385681 (MGI:2670551|PMID:12872135), (MGI:3028810|PMID:14764662), (MGI:3042099|PMID:12719478)
GO_REF:0000002		 RGD
InterPro		 PMID:12719478 PMID:12872135 PMID:14764662 GO_REF:0000002 MGI:2670551 MGI:3028810 MGI:3042099 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Reg3g regenerating family member 3 gamma involved_in ISS
ISO		 GO_REF:0000024
(MGI:3760234|PMID:17635956)		 UniProt
RGD		 PMID:17635956 GO_REF:0000024 MGI:3760234 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:108005 (MGI:3042099|PMID:12719478) RGD PMID:12719478 MGI:3042099 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:20037584)
UniProtKB:Q9EPW9 (MGI:4438693|PMID:20037584)		 Ensembl
RGD		 PMID:20037584 PMID:21873635 GO_REF:0000107 MGI:4438693, RGD:13792537 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO UniProtKB:Q9QUK6 (MGI:4438693|PMID:20037584)
(PMID:20037584)		 RGD PMID:20037584 MGI:4438693 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO UniProtKB:P22366 (MGI:3826712|PMID:18820679) RGD PMID:18820679 MGI:3826712 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in ISO (MGI:5305352|PMID:22011580) RGD PMID:22011580 MGI:5305352 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625 		JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (MGI:3836337|PMID:19265123) RGD PMID:19265123 MGI:3836337 NCBI chr 8:111,091,453...111,193,947
Ensembl chr 8:111,091,503...111,193,255 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794|MGI:3029019 (MGI:2669022|PMID:12855817), (MGI:2670551|PMID:12872135) RGD PMID:12855817 PMID:12872135 MGI:2669022 MGI:2670551 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) RGD PMID:17088249 NCBI chr 4:94,867,258...94,908,780
Ensembl chr 4:94,811,097...94,907,605 		JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim11 tripartite motif-containing 11 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27498865)		 UniProt
RGD		 PMID:27498865 GO_REF:0000024 NCBI chr10:43,758,299...43,771,138
Ensembl chr10:43,758,354...43,771,138 		JBrowse link
negative regulation of antifungal innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam3a FAM3 metabolism regulating signaling molecule A involved_in ISO (PMID:18212107) RGD PMID:18212107 NCBI chr  X:152,166,716...152,175,327
Ensembl chr  X:152,165,535...152,175,362 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:33093067)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:33093067 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26440888)		 Ensembl
RGD		 PMID:26440888 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aurkb aurora kinase B involved_in IEA
ISO		 GO_REF:0000107
(PMID:33542149)		 Ensembl
RGD		 PMID:33542149 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Banf1 BAF nuclear assembly factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:32792394)		 Ensembl
RGD		 PMID:32792394 GO_REF:0000107 NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in IEA
ISO		 GO_REF:0000107
(PMID:32911482), (PMID:32912999)		 Ensembl
RGD		 PMID:32911482 PMID:32912999 GO_REF:0000107 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:32715615) RGD PMID:32715615 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:35460603)		 Ensembl
RGD		 PMID:35460603 GO_REF:0000107 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:35322803)		 Ensembl
RGD		 PMID:35322803 GO_REF:0000107 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Ppp6c protein phosphatase 6, catalytic subunit involved_in IEA
ISO		 GO_REF:0000107
(PMID:32474700)		 Ensembl
RGD		 PMID:32474700 GO_REF:0000107 NCBI chr 3:22,929,816...22,962,123
Ensembl chr 3:22,931,577...22,962,113 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:33273464) RGD PMID:33273464 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:33476576)		 Ensembl
RGD		 PMID:33476576 GO_REF:0000107 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Zdhhc18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:35438208)		 Ensembl
RGD		 PMID:35438208 GO_REF:0000107 NCBI chr 5:145,821,534...145,859,989
Ensembl chr 5:145,831,446...145,859,993 		JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) RGD PMID:9029106 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO
IBA		 (PMID:23482636)
PMID:21873635		 RGD PMID:23482636 PMID:21873635 RGD:13792537 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in IBA
ISO		 PMID:21873635
UniProtKB:P01024 (PMID:17051150)		 RGD PMID:17051150 PMID:21873635 RGD:13792537 NCBI chr  X:61,144,926...61,170,212
Ensembl chr  X:61,144,928...61,170,212 		JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin involved_in ISO (PMID:12538697) RGD PMID:12538697 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Serping1 serpin family G member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10946292)		 UniProt
RGD		 PMID:10946292 GO_REF:0000024 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tarbp2 Tarbp2 subunit of RISC loading complex involved_in ISO (PMID:30927622) RGD PMID:30927622 NCBI chr 7:133,649,118...133,654,306
Ensembl chr 7:133,649,090...133,654,314 		JBrowse link
G Tspan6 tetraspanin 6 involved_in ISO (PMID:22908223) RGD PMID:22908223 NCBI chr  X:97,092,394...97,099,659
Ensembl chr  X:97,092,388...97,099,309 		JBrowse link
negative regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Atg12 autophagy related 12 involved_in ISO (MGI:3722754|PMID:17709747) RGD PMID:17709747 MGI:3722754 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 involved_in ISO
IEA		 (MGI:3722754|PMID:17709747)
GO_REF:0000107		 RGD
Ensembl		 PMID:17709747 GO_REF:0000107 MGI:3722754 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Aurkb aurora kinase B involved_in ISO
IEA		 (PMID:33542149)
GO_REF:0000107		 RGD
Ensembl		 PMID:33542149 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Banf1 BAF nuclear assembly factor 1 involved_in ISO (PMID:32792394) RGD PMID:32792394 NCBI chr 1:202,672,170...202,674,215
Ensembl chr 1:202,671,305...202,674,188 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 involved_in ISO (MGI:4943412|PMID:15557190) RGD PMID:15557190 MGI:4943412 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cep63 centrosomal protein 63 involved_in ISO
IEA		 (PMID:35793002)
GO_REF:0000107		 RGD
Ensembl		 PMID:35793002 GO_REF:0000107 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (PMID:21525357)
(MGI:5318004|PMID:21525357)		 RGD PMID:21525357 MGI:5318004 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO (MGI:5473736|PMID:23242137) RGD PMID:23242137 MGI:5473736 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 involved_in ISO (PMID:27692986), (PMID:35793002) RGD PMID:27692986 PMID:35793002 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818 		JBrowse link
G Grn granulin precursor involved_in ISS
ISO		 GO_REF:0000024
(MGI:4421471|PMID:20026663)		 UniProt
RGD		 PMID:20026663 GO_REF:0000024 MGI:4421471 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Lyar Ly1 antibody reactive involved_in IEA
ISO		 GO_REF:0000107
(PMID:31413131)		 Ensembl
RGD		 PMID:31413131 GO_REF:0000107 NCBI chr14:72,576,878...72,590,854
Ensembl chr14:72,576,879...72,590,612 		JBrowse link
G Mir181b1 microRNA 181b-1 involved_in ISO ENSEMBL_GeneID:ENSG00000171049 (PMID:25505240) RGD PMID:25505240 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir181b2 microRNA 181b-2 involved_in ISO ENSEMBL_GeneID:ENSG00000171049 (PMID:25505240) RGD PMID:25505240 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:22286305) RGD PMID:22286305 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (MGI:5568884|PMID:24560620) RGD PMID:24560620 MGI:5568884 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Nlrp4 NLR family, pyrin domain containing 4 involved_in ISO (PMID:27692986) RGD PMID:27692986 NCBI chr 1:68,089,321...68,132,429
Ensembl chr 1:68,089,321...68,127,521 		JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5141085 (MGI:5050761|PMID:21703540)		 Ensembl
RGD		 PMID:21703540 GO_REF:0000107 MGI:5050761 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484 		JBrowse link
G Nmi N-myc (and STAT) interactor involved_in
acts_upstream_of_or_within		 ISO (PMID:26342464)
(MGI:5546557|PMID:23956435)		 RGD PMID:23956435 PMID:26342464 MGI:5546557 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:7286108|PMID:35460603)
(PMID:32844745), (PMID:35460603)		 UniProt
RGD		 PMID:32844745 PMID:35460603 GO_REF:0000024 MGI:7286108 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
PMID:21873635
(MGI:3831253|PMID:18849341)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18849341 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3831253, RGD:13792537 NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525 		JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in ISO (PMID:33476576) RGD PMID:33476576 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Trim21 tripartite motif-containing 21 involved_in ISO (PMID:26342464) RGD PMID:26342464 NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
UniProtKB:Q00993|UniProtKB:Q60805 (MGI:3773763|PMID:18083102)		 UniProt
Ensembl
RGD		 PMID:18083102 GO_REF:0000024 GO_REF:0000107 MGI:3773763 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
G Usp38 ubiquitin specific peptidase 38 involved_in ISO (PMID:27692986) RGD PMID:27692986 NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta involved_in ISO (PMID:35662396) RGD PMID:35662396 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668 		JBrowse link
G Zdhhc18 zinc finger DHHC-type palmitoyltransferase 18 involved_in ISO
IEA
ISS		 (PMID:35438208)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:35438208 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:145,821,534...145,859,989
Ensembl chr 5:145,831,446...145,859,993 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO
IEA
ISS		 (PMID:19164550)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (PMID:21187438) RGD PMID:21187438 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:25865883) RGD PMID:25865883 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17600090)		 UniProt
Ensembl
RGD		 PMID:17600090 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:22043923) RGD PMID:22043923 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Cd300lf Cd300 molecule-like family member F involved_in ISS
ISO		 GO_REF:0000024
(PMID:22043923)		 UniProt
RGD		 PMID:22043923 GO_REF:0000024 NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041 		JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sarm1 sterile alpha and TIR motif containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:63,369,456...63,393,016
Ensembl chr10:63,369,456...63,392,822 		JBrowse link
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd96 CD96 molecule acts_upstream_of_or_within ISO MGI:5617136 (MGI:5569209|PMID:24658051) RGD PMID:24658051 MGI:5569209 NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO
IEA		 (PMID:18604210)
GO_REF:0000107		 RGD
Ensembl		 PMID:18604210 GO_REF:0000107 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Clec12b C-type lectin domain family 12, member B involved_in ISO (PMID:17562706) RGD PMID:17562706 NCBI chr 4:162,827,462...162,843,821
Ensembl chr 4:162,827,462...162,838,946 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein IMP RGD PMID:18835194 RGD:11568650 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration IDA RGD PMID:9021955 RGD:9685777 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869 		JBrowse link
G Igf2 insulin-like growth factor 2 IDA RGD PMID:9021955 RGD:9685777 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206), (PMID:9486650) RGD PMID:9485206 PMID:9486650 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425 		JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IEA
ISS		 (PMID:9486650)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9486650 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23408620) RGD PMID:23408620 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G RT1-A1 RT1 class Ia, locus A1 IMP RGD PMID:10837412 RGD:2313500 NCBI chr20:4,905,309...4,914,593 JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:10799855), (PMID:17179229), (PMID:23335510), (PMID:9486650) RGD PMID:9486650 PMID:10799855 PMID:17179229 PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:10190900), (PMID:12874224) RGD PMID:10190900 PMID:12874224 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:3641175 (MGI:3639618|PMID:16127454) RGD PMID:16127454 MGI:3639618 NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509 		JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:23696226)
(MGI:5512785|PMID:23696226)
GO_REF:0000024		 RGD
UniProt		 PMID:23696226 GO_REF:0000024 MGI:5512785 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) RGD PMID:22842346 MGI:5437532 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Klre1 killer cell lectin like receptor E1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:24586048) RGD PMID:24586048 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS		 (PMID:29164996)
GO_REF:0000024		 RGD
UniProt		 PMID:29164996 GO_REF:0000024 NCBI chr 5:166,474,947...166,479,103
Ensembl chr 5:166,474,966...166,479,017 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6787653|PMID:34615873)		 UniProt
RGD		 PMID:34615873 GO_REF:0000024 MGI:6787653 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 involved_in ISO (PMID:26037928) RGD PMID:26037928 NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO (PMID:36586411) RGD PMID:36586411 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO		 GO_REF:0000024
(MGI:6282153|PMID:30612879)
(PMID:30612879)		 UniProt
RGD		 PMID:30612879 GO_REF:0000024 MGI:6282153 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO (PMID:36586411) RGD PMID:36586411 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISS
ISO		 GO_REF:0000024
(PMID:26347139)		 UniProt
RGD		 PMID:26347139 GO_REF:0000024 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,551,378...11,585,027
Ensembl chr10:11,551,356...11,584,398 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5488534|PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (MGI:6391726|PMID:29887864)
(PMID:32514138)		 RGD PMID:29887864 PMID:32514138 MGI:6391726 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO (PMID:27929086)
(MGI:5907951|PMID:27929086)		 RGD PMID:27929086 MGI:5907951 NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Zdhhc12 zinc finger DHHC-type palmitoyltransferase 12 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:36586411)		 UniProt
Ensembl
RGD		 PMID:36586411 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:13,363,504...13,366,383
Ensembl chr 3:13,363,504...13,366,474 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:3777503|PMID:18342009) RGD PMID:18342009 MGI:3777503 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbin erbb2 interacting protein involved_in ISO (PMID:16203728)
(MGI:5640951|PMID:16203728)		 RGD PMID:16203728 MGI:5640951 NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in IBA
ISO		 PMID:21873635
(MGI:5640942|PMID:23991106)
(PMID:23991106)		 RGD PMID:23991106 PMID:21873635 MGI:5640942, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:3777503|PMID:18342009) RGD PMID:18342009 MGI:3777503 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Znrf4 zinc and ring finger 4 involved_in ISO (PMID:28656966) RGD PMID:28656966 NCBI chr 9:1,353,308...1,354,496
Ensembl chr 9:1,353,306...1,354,584 		JBrowse link
negative regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (MGI:4366202|PMID:19696743) RGD PMID:19696743 MGI:4366202 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Grn granulin precursor involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:12526812)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12526812 GO_REF:0000024 GO_REF:0000107 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:11443198) RGD PMID:11443198 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15750715) RGD PMID:15750715 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508 		JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO MGI:5442794 (MGI:5752697|PMID:25799045) RGD PMID:25799045 MGI:5752697 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211 		JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO
IEA
ISS		 (PMID:19164550)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IBA		 (PMID:18411269), (PMID:21187438)
PMID:21873635
(MGI:3836702|PMID:17475874)		 RGD PMID:17475874 PMID:18411269 PMID:21187438 PMID:21873635 MGI:3836702, RGD:13792537 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Gpatch3 G patch domain containing 3 involved_in ISO
IBA		 (PMID:28414768)
PMID:21873635		 RGD PMID:28414768 PMID:21873635 RGD:13792537 NCBI chr 5:145,800,107...145,809,519
Ensembl chr 5:145,800,111...145,809,250 		JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5141085 (MGI:5050761|PMID:21703540)		 Ensembl
RGD		 PMID:21703540 GO_REF:0000107 MGI:5050761 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor involved_in ISO
IEA
ISS		 (PMID:26471729)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26471729 GO_REF:0000024 GO_REF:0000107 NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913 		JBrowse link
G Rnf125 ring finger protein 125 involved_in ISO (PMID:17460044), (PMID:26471729) RGD PMID:17460044 PMID:26471729 NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983 		JBrowse link
G Sec14l1 SEC14-like lipid binding 1 involved_in ISO
IBA		 (PMID:23843640)
PMID:21873635		 RGD PMID:23843640 PMID:21873635 RGD:13792537 NCBI chr10:102,319,920...102,367,070
Ensembl chr10:102,319,920...102,367,068 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 involved_in ISO
IEA
ISS		 (PMID:26471729)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26471729 GO_REF:0000024 GO_REF:0000107 NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087 		JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:4456928|PMID:20385881)		 UniProt
RGD		 PMID:20385881 GO_REF:0000024 MGI:4456928 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:26599367)
(MGI:6162316|PMID:26599367)		 RGD PMID:26599367 MGI:6162316 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (MGI:3050756|PMID:15220916) RGD PMID:15220916 MGI:3050756 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949) RGD PMID:22198949 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695864|PMID:31134514) RGD PMID:31134514 MGI:6695864 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) RGD PMID:19865078 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:15474016) RGD PMID:15474016 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5619743|PMID:21695056)		 Ensembl
RGD		 PMID:21695056 GO_REF:0000107 MGI:5619743 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Bpifb1 BPI fold containing family B, member 1 involved_in ISO
IEA
IBA		 (PMID:21900486)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:21900486 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19948740)		 UniProt
Ensembl
RGD		 PMID:19948740 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:4456928|PMID:20385881)		 UniProt
RGD		 PMID:20385881 GO_REF:0000024 MGI:4456928 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28609714) RGD PMID:28609714 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mir140 microRNA 140 involved_in ISO UniProtKB:O00206 (PMID:30233718), (PMID:30321456) RGD PMID:30233718 PMID:30321456 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir200b microRNA 200b involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mir200c microRNA 200c involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:29653364) RGD PMID:29653364 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir708 microRNA 708 involved_in ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISO
IEA		 (PMID:18511497)
GO_REF:0000107		 RGD
Ensembl		 PMID:18511497 GO_REF:0000107 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO (MGI:3834524|PMID:17395780) RGD PMID:17395780 MGI:3834524 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184) RGD PMID:19412184 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6152919|PMID:29407460), (MGI:6695864|PMID:31134514) RGD PMID:29407460 PMID:31134514 MGI:6152919 MGI:6695864 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:4943853|PMID:19912257) RGD PMID:19912257 MGI:4943853 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gramd4 GRAM domain containing 4 involved_in IBA
ISO		 PMID:21873635
(MGI:6274965|PMID:25917084)		 RGD PMID:25917084 PMID:21873635 MGI:6274965, RGD:13792537 NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053 		JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISO
IEA		 (PMID:26231120)
GO_REF:0000107		 RGD
Ensembl		 PMID:26231120 GO_REF:0000107 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO (MGI:4355098|PMID:19587007) RGD PMID:19587007 MGI:4355098 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO
IEA		 (MGI:3662828|PMID:16378096)
GO_REF:0000107		 RGD
Ensembl		 PMID:16378096 GO_REF:0000107 MGI:3662828 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6220977|PMID:30332431)		 UniProt
Ensembl
RGD		 PMID:30332431 GO_REF:0000024 GO_REF:0000107 MGI:6220977 NCBI chr 9:2,120,740...2,131,771
Ensembl chr 9:2,120,744...2,132,572 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) RGD PMID:28039360 MGI:5896692 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO MGI:2387941 (MGI:3608246|PMID:16236719) RGD PMID:16236719 MGI:3608246 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5499954|PMID:23589304)		 UniProt
RGD		 PMID:23589304 GO_REF:0000024 MGI:5499954 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in ISO
IEA
ISS		 (PMID:27426725)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:27426725 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:108,430,755...108,437,118
Ensembl chr 7:108,430,792...108,437,111 		JBrowse link
G Mir140 microRNA 140 IMP RGD PMID:31376096 RGD:329337378 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:26041742) RGD PMID:26041742 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir19a microRNA 19a involved_in ISO (PMID:26041742) RGD PMID:26041742 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISO
IBA
ISS		 (PMID:20829348)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:20829348 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:5085850 (MGI:5432950|PMID:22763455)
GO_REF:0000107		 RGD
Ensembl		 PMID:22763455 GO_REF:0000107 MGI:5432950 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in IBA
ISO		 PMID:21873635
(MGI:6120140|PMID:29395066)
(PMID:29395066)		 RGD PMID:29395066 PMID:21873635 MGI:6120140, RGD:13792537 NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA		 (MGI:4821539|PMID:20584979)
GO_REF:0000107		 RGD
Ensembl		 PMID:20584979 GO_REF:0000107 MGI:4821539 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5487531|PMID:20728433) RGD PMID:20728433 MGI:5487531 NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
G Ptgs2os prostaglandin-endoperoxide synthase 2, opposite strand acts_upstream_of_or_within ISO (MGI:5502463|PMID:23907535) RGD PMID:23907535 MGI:5502463 NCBI chr13:62,160,002...62,163,710 JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B involved_in ISO (MGI:5689225|PMID:26095358) RGD PMID:26095358 MGI:5689225 NCBI chr 5:144,944,618...144,966,703
Ensembl chr 5:144,944,636...144,966,720 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
UniProtKB:Q00993|UniProtKB:Q60805 (MGI:3773763|PMID:18083102)		 UniProt
Ensembl
RGD		 PMID:18083102 GO_REF:0000024 GO_REF:0000107 MGI:3773763 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142 		JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3828307 (MGI:3821394|PMID:19060901)
GO_REF:0000107		 RGD
Ensembl		 PMID:19060901 GO_REF:0000107 MGI:3821394 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO (PMID:23386060) RGD PMID:23386060 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO (PMID:27782195) RGD PMID:27782195 NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E family member 2 involved_in ISO (PMID:35878012) RGD PMID:35878012 NCBI chr 9:87,886,126...87,914,470
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO (PMID:35878012) RGD PMID:35878012 NCBI chr 9:88,001,212...88,127,040
Ensembl chr 9:88,001,301...88,125,715 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (PMID:28724761) RGD PMID:28724761 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5583923|PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO
IBA		 (PMID:20434986)
PMID:21873635
(MGI:4454346|PMID:20434986)		 RGD PMID:20434986 PMID:21873635 MGI:4454346, RGD:13792537 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
IEA
ISS		 (PMID:11909529)
GO_REF:0000107
(MGI:3691503|PMID:11909529), (MGI:5493216|PMID:12138178)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11909529 PMID:12138178 GO_REF:0000024 GO_REF:0000107 MGI:3691503 MGI:5493216 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:29670289)
(MGI:5521417|PMID:23972988)		 RGD PMID:23972988 PMID:29670289 MGI:5521417 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO (PMID:28165510)
(MGI:6508512|PMID:28165510)		 RGD PMID:28165510 MGI:6508512 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:3834787|PMID:18724932) RGD PMID:18724932 MGI:3834787 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 involved_in ISO (PMID:28011935) RGD PMID:28011935 NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) RGD PMID:28165510 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 involved_in ISO (MGI:6316470|PMID:30591559) RGD PMID:30591559 MGI:6316470 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
negative regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (PMID:16709924)
GO_REF:0000107		 RGD
Ensembl		 PMID:16709924 GO_REF:0000107 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:11679576) RGD PMID:11679576 NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Otop1 otopetrin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5750846|PMID:24379350)		 UniProt
RGD		 PMID:24379350 GO_REF:0000024 MGI:5750846 NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300)
(MGI:5905929|PMID:27796300)		 RGD PMID:27796300 MGI:5905929 NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:21268089) RGD PMID:21268089 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5493216|PMID:12138178)		 UniProt
Ensembl
RGD		 PMID:12138178 GO_REF:0000024 GO_REF:0000107 MGI:5493216 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp1a NLR family, pyrin domain containing 1A involved_in ISO (PMID:22665479), (PMID:27662089), (PMID:31484767), (PMID:33243852), (PMID:33420028), (PMID:33420033), (PMID:33852854), (PMID:35594856) RGD PMID:22665479 PMID:27662089 PMID:31484767 PMID:33243852 PMID:33420028 More... NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5488534|PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO MGI:2180015 (MGI:6363385|PMID:28928055) RGD PMID:28928055 MGI:6363385 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 acts_upstream_of_or_within
involved_in		 ISO
ISS		 MGI:5465108 (MGI:5446983|PMID:22753929)
(PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502)
(MGI:5492224|PMID:23582325), (MGI:5780643|PMID:26173909), (MGI:5792478|PMID:27043286), (MGI:5913002|PMID:28716882), (MGI:5921465|PMID:28656979), (MGI:6106673|PMID:28943315), (MGI:6260219|PMID:30487600), (MGI:6787653|PMID:34615873), (MGI:6844859|PMID:34861190), (MGI:6859739|PMID:28465465)
GO_REF:0000024		 RGD
UniProt		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More... GO_REF:0000024 MGI:5446983 MGI:5492224 MGI:5780643 MGI:5792478 MGI:5913002 MGI:5921465 MGI:6106673 MGI:6260219 MGI:6787653 MGI:6844859 MGI:6859739 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:27432880) RGD PMID:27432880 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5488534|PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp6 NLR family, pyrin domain containing 6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6706628|PMID:32424362), (MGI:6833928|PMID:34678144)
(PMID:30674671), (PMID:31932628), (PMID:34678144)		 UniProt
Ensembl
RGD		 PMID:30674671 PMID:31932628 PMID:32424362 PMID:34678144 GO_REF:0000024 GO_REF:0000107 MGI:6706628 MGI:6833928 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 involved_in ISO (PMID:11058605), (PMID:12791997), (PMID:12796777)
(MGI:6210191|PMID:27007849)		 RGD PMID:11058605 PMID:12791997 PMID:12796777 PMID:27007849 MGI:6210191 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO MGI:2660793 (MGI:2176422|PMID:11894098)
(PMID:29452636), (PMID:30279485)		 RGD PMID:11894098 PMID:29452636 PMID:30279485 MGI:2176422 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO
IEA		 (PMID:29452636)
GO_REF:0000107		 RGD
Ensembl		 PMID:29452636 GO_REF:0000107 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:25891078) RGD PMID:25891078 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:31875558) RGD PMID:31875558 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (MGI:3775161|PMID:18261938) RGD PMID:18261938 MGI:3775161 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO (MGI:5562512|PMID:23892723)
(MGI:3529429|PMID:15692052), (MGI:6210191|PMID:27007849)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195)
(PMID:12527755)		 RGD PMID:12527755 PMID:12626759 PMID:15044951 PMID:15692052 PMID:17355968 More... MGI:3529429 MGI:5562512 MGI:6210191 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity involved_in ISO (PMID:23806334) RGD PMID:23806334 NCBI chr 2:78,290,437...78,316,633
Ensembl chr 2:78,290,959...78,316,422 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within ISO (PMID:12527755) RGD PMID:12527755 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO MGI:2660793 (MGI:2176422|PMID:11894098)
(MGI:7484276|PMID:17947236)
(PMID:16824733), (PMID:17355968), (PMID:17562858), (PMID:23806334), (PMID:28545134), (PMID:29452636), (PMID:30026309), (PMID:30279485), (PMID:30478312)		 RGD PMID:11894098 PMID:16824733 PMID:17355968 PMID:17562858 PMID:17947236 More... MGI:2176422 MGI:7484276 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3775161|PMID:18261938)
GO_REF:0000107		 RGD
Ensembl		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19667203), (PMID:22607974), (PMID:29452636)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19667203 PMID:22607974 PMID:29452636 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23258413) RGD PMID:23258413 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Clec4e C-type lectin domain family 4, member E involved_in ISO
ISS		 (PMID:24101491)
GO_REF:0000024		 RGD
UniProt		 PMID:24101491 GO_REF:0000024 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945), (PMID:31875558) RGD PMID:28593945 PMID:31875558 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 involved_in ISO (PMID:31649195) RGD PMID:31649195 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:31649195) RGD PMID:31649195 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378) RGD PMID:23910378 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp2 guanylate binding protein 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5774627|PMID:25774716), (MGI:5774628|PMID:25774715)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:25774715 PMID:25774716 GO_REF:0000024 GO_REF:0000107 MGI:5774627 MGI:5774628 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (MGI:5774627|PMID:25774716), (MGI:5774628|PMID:25774715) RGD PMID:25774715 PMID:25774716 MGI:5774627 MGI:5774628 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
positive regulation of antifungal innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g5 phospholipase A2, group V involved_in ISS
ISO		 GO_REF:0000024
(MGI:3841317|PMID:19342668)		 UniProt
RGD		 PMID:19342668 GO_REF:0000024 MGI:3841317 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (MGI:6381024|PMID:30911105) RGD PMID:30911105 MGI:6381024 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Trim62 tripartite motif-containing 62 involved_in ISO (PMID:26488816)
(MGI:5788367|PMID:26488816)		 RGD PMID:26488816 MGI:5788367 NCBI chr 5:141,230,830...141,260,629
Ensembl chr 5:141,231,523...141,259,915 		JBrowse link
positive regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009349|PMID:20683884) RGD PMID:20683884 MGI:5009349 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Akirin2 akirin 2 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(MGI:5607662|PMID:25107474)		 UniProt
RGD		 PMID:25107474 PMID:21873635 GO_REF:0000024 MGI:5607662, RGD:13792537 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568 		JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (MGI:3697751|PMID:17187069) RGD PMID:17187069 MGI:3697751 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Coch cochlin acts_upstream_of_or_within ISO MGI:3624560 (MGI:5525040|PMID:23684986) RGD PMID:23684986 MGI:5525040 NCBI chr 6:69,031,139...69,045,124
Ensembl chr 6:69,031,167...69,045,109 		JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (MGI:5908739|PMID:28636595) RGD PMID:28636595 MGI:5908739 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Ereg epiregulin involved_in ISS
ISO		 GO_REF:0000024
(MGI:3604223|PMID:16182244)		 UniProt
RGD		 PMID:16182244 GO_REF:0000024 MGI:3604223 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Fadd Fas associated via death domain involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in ISO (PMID:25505240) RGD PMID:25505240 NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (MGI:5319585|PMID:22461501) RGD PMID:22461501 MGI:5319585 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO UniProtKB:O08573 (MGI:4839671|PMID:20937702) RGD PMID:20937702 MGI:4839671 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:4367121 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgb2 high mobility group box 2 involved_in ISO (MGI:4367121|PMID:19890330) RGD PMID:19890330 MGI:4367121 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Ifi35 interferon-induced protein 35 involved_in ISO (PMID:29038465)
(MGI:6099204|PMID:29038465)		 RGD PMID:29038465 MGI:6099204 NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO (PMID:32817552) RGD PMID:32817552 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Lgals9 galectin 9 involved_in ISO UniProtKB:Q8VIM0 (MGI:4839671|PMID:20937702) RGD PMID:20937702 MGI:4839671 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Mmp2 matrix metallopeptidase 2 acts_upstream_of_or_within ISO (MGI:5435352|PMID:22509276) RGD PMID:22509276 MGI:5435352 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Nmi N-myc (and STAT) interactor involved_in ISO (MGI:6099204|PMID:29038465) RGD PMID:29038465 MGI:6099204 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:4946442|PMID:21156799)
MGI:3529594 (MGI:3528786|PMID:15692051)		 RGD PMID:15692051 PMID:21156799 MGI:3528786 MGI:4946442 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5284800|PMID:15308695)
(PMID:15308695)		 UniProt
RGD		 PMID:15308695 GO_REF:0000024 MGI:5284800 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692 		JBrowse link
G Polr3b RNA polymerase III subunit B involved_in ISO (PMID:19609254) RGD PMID:19609254 NCBI chr 7:19,039,179...19,142,450
Ensembl chr 7:19,038,552...19,142,598 		JBrowse link
G Polr3c RNA polymerase III subunit C involved_in ISO
IEA
ISS		 (PMID:19609254)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19609254 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:184,246,201...184,262,150
Ensembl chr 2:184,246,204...184,262,208 		JBrowse link
G Polr3d RNA polymerase III subunit D involved_in ISO (PMID:19631370) RGD PMID:19631370 NCBI chr15:45,511,587...45,516,256
Ensembl chr15:45,511,589...45,516,353 		JBrowse link
G Polr3f RNA polymerase III subunit F involved_in ISO (PMID:19631370) RGD PMID:19631370 NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837 		JBrowse link
G Polr3g RNA polymerase III subunit G involved_in ISO (PMID:19609254), (PMID:19631370) RGD PMID:19609254 PMID:19631370 NCBI chr 2:11,945,215...11,986,125
Ensembl chr 2:11,945,217...11,986,125 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:24807708) RGD PMID:24807708 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO (PMID:28273161) RGD PMID:28273161 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:32433612)		 UniProt
RGD		 PMID:32433612 GO_REF:0000024 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in ISO (MGI:5287349|PMID:21531336) RGD PMID:21531336 MGI:5287349 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) RGD PMID:32433612 NCBI chr  X:50,403,962...50,423,141
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (MGI:3713420|PMID:16301656) RGD PMID:16301656 MGI:3713420 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO (PMID:16123302) RGD PMID:16123302 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (PMID:29426904) RGD PMID:29426904 NCBI chr12:19,544,913...19,567,324
Ensembl chr12:19,551,521...19,567,462 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) RGD PMID:22328336 NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 involved_in ISO (PMID:21791617) RGD PMID:21791617 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (MGI:4421606|PMID:20080593) RGD PMID:20080593 MGI:4421606 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Usp17li ubiquitin specific peptidase 17-like I involved_in ISO (PMID:20368735) RGD PMID:20368735 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:17307798) RGD PMID:17307798 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Cd226 CD226 molecule involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:4454325 (MGI:5569209|PMID:24658051)		 RGD PMID:24658051 PMID:21873635 MGI:5569209, RGD:13792537 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (MGI:3774350|PMID:16439675) RGD PMID:16439675 MGI:3774350 NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (MGI:3028812|PMID:14764669) RGD PMID:14764669 MGI:3028812 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:16366734), (PMID:19304799), (PMID:23184984) RGD PMID:16366734 PMID:19304799 PMID:23184984 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA		 (PMID:23632890)
GO_REF:0000107		 RGD
Ensembl		 PMID:23632890 GO_REF:0000107 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,633...37,831,134
Ensembl chr19:37,744,633...37,829,167 		JBrowse link
G Cadm1 cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:15811952)
(MGI:3689781|PMID:15811952)
GO_REF:0000024		 RGD
HGNC		 PMID:15811952 GO_REF:0000024 MGI:3689781 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:12486241), (PMID:17307798) RGD PMID:12486241 PMID:17307798 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
G Cd226 CD226 molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (PMID:15811952)
(MGI:3689781|PMID:15811952)		 RGD PMID:15811952 MGI:3689781 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15100275 RGD:2303778 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:2204066) RGD PMID:2204066 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein acts_upstream_of_or_within ISO MGI:3579137 (MGI:3578455|PMID:15843532) RGD PMID:15843532 MGI:3578455 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959 		JBrowse link
G Il21 interleukin 21 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:18005035)
GO_REF:0000107
(MGI:3028812|PMID:14764669)
PMID:21873635		 RGD
Ensembl		 PMID:14764669 PMID:18005035 PMID:21873635 GO_REF:0000107 MGI:3028812, RGD:13792537 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425 		JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO
IBA		 (PMID:9754572)
PMID:21873635		 RGD PMID:9754572 PMID:21873635 RGD:13792537 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843 		JBrowse link
G Klrc3 killer cell lectin like receptor C3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,105,081...163,112,737
Ensembl chr 4:163,106,024...163,112,336 		JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IBA
IEA		 (PMID:9754572)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:9754572 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518 		JBrowse link
G Klre1 killer cell lectin like receptor E1 involved_in ISO
IBA		 (PMID:15294961)
PMID:21873635		 RGD PMID:15294961 PMID:21873635 RGD:13792537 NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Klri1 killer cell lectin-like receptor family I member 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,183,675...163,218,903
Ensembl chr 4:163,183,669...163,218,870 		JBrowse link
G Klri2 killer cell lectin-like receptor family I member 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:163,252,844...163,261,484
Ensembl chr 4:163,252,844...163,261,484 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000002
(MGI:3054301|PMID:15294961)
(MGI:2450811|PMID:12645935)
GO_REF:0000107
(PMID:15294961)
PMID:21873635		 UniProt
InterPro
RGD
Ensembl		 PMID:12645935 PMID:15294961 PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 MGI:2450811 MGI:3054301, RGD:13792537 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Lag3 lymphocyte activating 3 acts_upstream_of_or_within ISO MGI:2176269 (MGI:80003|PMID:8602528) RGD PMID:8602528 MGI:80003 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G Ly49s3 Ly-49 stimulatory receptor 3 IDA RGD PMID:12077224 RGD:633264 Ensembl chr 4:164,122,072...164,341,692 JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO
IEA
IBA		 (PMID:16304049)
GO_REF:0000107
GO_REF:0000002
PMID:21873635		 RGD
Ensembl
InterPro		 PMID:16304049 PMID:21873635 GO_REF:0000002 GO_REF:0000107, RGD:13792537 NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:16304049) RGD PMID:16304049 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Raet1e retinoic acid early transcript 1E involved_in ISO (PMID:18544572) RGD PMID:18544572 NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755 		JBrowse link
G Raet1l retinoic acid early transcript 1L IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,979,433...1,984,410
Ensembl chr 1:1,979,443...1,984,410 		JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IDA RGD PMID:20306467 RGD:9685184 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO
IEA		 (PMID:19933860)
GO_REF:0000107		 RGD
Ensembl		 PMID:19933860 GO_REF:0000107 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:23335510) RGD PMID:23335510 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 acts_upstream_of_or_within ISO MGI:3701255 (MGI:3700871|PMID:16476767) RGD PMID:16476767 MGI:3700871 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Sh2d1a SH2 domain containing 1A acts_upstream_of_or_within ISO MGI:1349420|MGI:3575311|MGI:3622649 (MGI:3639618|PMID:16127454), (MGI:4355255|PMID:19648922) RGD PMID:16127454 PMID:19648922 MGI:3639618 MGI:4355255 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:1328352|MGI:1349420|MGI:98923 (MGI:4355255|PMID:19648922), (MGI:4839659|PMID:20962259) RGD PMID:19648922 PMID:20962259 MGI:4355255 MGI:4839659 NCBI chr13:82,437,418...82,461,511
Ensembl chr13:82,437,428...82,461,509 		JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (PMID:16920955) RGD PMID:16920955 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:1857249 (MGI:3655409|PMID:9841920) RGD PMID:9841920 MGI:3655409 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2181592 (MGI:3655409|PMID:9841920)		 Ensembl
RGD		 PMID:9841920 GO_REF:0000107 MGI:3655409 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1349420|MGI:3622649 (MGI:4839659|PMID:20962259)
GO_REF:0000107		 RGD
Ensembl		 PMID:20962259 GO_REF:0000107 MGI:4839659 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in IBA
ISO		 PMID:21873635
(PMID:12913096)		 RGD PMID:12913096 PMID:21873635 RGD:13792537 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in IBA
ISO		 PMID:21873635
(MGI:3689781|PMID:15811952)
(PMID:15811952)		 RGD PMID:15811952 PMID:21873635 MGI:3689781, RGD:13792537 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:7903063)
GO_REF:0000107		 RGD
Ensembl		 PMID:7903063 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:7903063) RGD PMID:7903063 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IBA
ISO		 PMID:21873635
(PMID:12913096)		 RGD PMID:12913096 PMID:21873635 RGD:13792537 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656 		JBrowse link
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (MGI:5644003|PMID:25711213) RGD PMID:25711213 MGI:5644003 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
positive regulation of natural killer cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dpp4 dipeptidylpeptidase 4 IMP RGD PMID:19327106 RGD:41408336 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:9754572) RGD PMID:9754572 NCBI chr20:4,870,939...4,910,183 JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5488534|PMID:23502856)
GO_REF:0000107		 RGD
Ensembl		 PMID:23502856 GO_REF:0000107 MGI:5488534 NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28943315)
(MGI:7387171|PMID:23246432)		 UniProt
RGD		 PMID:23246432 PMID:28943315 GO_REF:0000024 MGI:7387171 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080 		JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO (PMID:34554188)
(MGI:7276081|PMID:34554188)		 RGD PMID:34554188 MGI:7276081 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Casp4 caspase 4 involved_in ISO (MGI:5780643|PMID:26173909) RGD PMID:26173909 MGI:5780643 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cd36 CD36 molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5546292|PMID:23812099)		 UniProt
Ensembl
RGD		 PMID:23812099 GO_REF:0000024 GO_REF:0000107 MGI:5546292 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd36l1 CD36 molecule like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (MGI:6368386|PMID:31511697) RGD PMID:31511697 MGI:6368386 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO (PMID:23871209) RGD PMID:23871209 NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6106673|PMID:28943315)
(PMID:28943315)		 UniProt
Ensembl
RGD		 PMID:28943315 GO_REF:0000024 GO_REF:0000107 MGI:6106673 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO (PMID:28656979)
(MGI:5921465|PMID:28656979)		 RGD PMID:28656979 MGI:5921465 NCBI chr 1:79,075,353...79,108,882
Ensembl chr 1:79,068,904...79,108,556 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:23582325)
(MGI:5492224|PMID:23582325)		 RGD PMID:23582325 MGI:5492224 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mir21 microRNA 21 IDA RGD PMID:29084974 RGD:41404715 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:33718825)		 UniProt
RGD		 PMID:33718825 GO_REF:0000024 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nek7 NIMA-related kinase 7 involved_in ISO
IEA
ISS		 (MGI:5698271|PMID:26642356), (MGI:5751332|PMID:26814970)
(PMID:31189953), (PMID:36442502)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 GO_REF:0000024 GO_REF:0000107 MGI:5698271 MGI:5751332 NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:32514138)
GO_REF:0000107		 RGD
Ensembl		 PMID:32514138 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(MGI:6859739|PMID:28465465)		 UniProt
RGD		 PMID:28465465 GO_REF:0000024 MGI:6859739 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5913002|PMID:28716882)		 UniProt
RGD		 PMID:28716882 GO_REF:0000024 MGI:5913002 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:27043286)
(MGI:5792478|PMID:27043286)		 RGD PMID:27043286 MGI:5792478 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (MGI:6384515|PMID:31836654) RGD PMID:31836654 MGI:6384515 NCBI chr 4:63,927,523...63,937,355 JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5546292|PMID:23812099)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23812099 GO_REF:0000024 GO_REF:0000107 MGI:5546292 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (MGI:5546292|PMID:23812099) RGD PMID:23812099 MGI:5546292 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (MGI:5888801|PMID:28094437)
(PMID:28094437)		 RGD PMID:28094437 MGI:5888801 NCBI chr 3:114,012,104...114,035,468
Ensembl chr 3:114,011,702...114,035,476 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:6278628|PMID:21277849), (MGI:6450424|PMID:19570976)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19570976 PMID:21277849 GO_REF:0000024 GO_REF:0000107 MGI:6278628 MGI:6450424 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Slc46a2 solute carrier family 46, member 2 involved_in ISO (PMID:28539433) RGD PMID:28539433 NCBI chr 5:74,800,226...74,808,128
Ensembl chr 5:74,800,226...74,808,128 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3775161|PMID:18261938)		 Ensembl
RGD		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Nagk N-acetylglucosamine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:7484284|PMID:36002575)
(PMID:36002575)		 UniProt
RGD		 PMID:36002575 GO_REF:0000024 MGI:7484284 NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (MGI:5562512|PMID:23892723) RGD PMID:23892723 MGI:5562512 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5571205|PMID:24695226)		 UniProt
RGD		 PMID:24695226 GO_REF:0000024 MGI:5571205 NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5571205|PMID:24695226)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24695226 GO_REF:0000024 GO_REF:0000107 MGI:5571205 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3775161|PMID:18261938)		 Ensembl
RGD		 PMID:18261938 GO_REF:0000107 MGI:3775161 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO (PMID:31649195)
(MGI:6414746|PMID:31649195)		 RGD PMID:31649195 MGI:6414746 NCBI chr 3:69,772,037...69,800,142
Ensembl chr 3:69,771,890...69,799,921 		JBrowse link
positive regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA		 (MGI:1097829|PMID:9338787)
GO_REF:0000107		 RGD
Ensembl		 PMID:9338787 GO_REF:0000107 MGI:1097829 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15750715) RGD PMID:15750715 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508 		JBrowse link
positive regulation of response to type II interferon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (MGI:3807609|PMID:18641331) RGD PMID:18641331 MGI:3807609 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) RGD PMID:22328336 NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 involved_in ISO (PMID:21791617) RGD PMID:21791617 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (MGI:4421606|PMID:20080593) RGD PMID:20080593 MGI:4421606 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like involved_in ISO (PMID:25925578) RGD PMID:25925578 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Pum1 pumilio RNA-binding family member 1 involved_in ISO (PMID:25340845) RGD PMID:25340845 NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039 		JBrowse link
G Pum2 pumilio RNA-binding family member 2 involved_in ISO (PMID:25340845) RGD PMID:25340845 NCBI chr 6:31,462,879...31,542,976
Ensembl chr 6:31,462,872...31,542,976 		JBrowse link
G Trim15 tripartite motif containing 15 involved_in ISO (PMID:23077300) RGD PMID:23077300 NCBI chr20:1,700,905...1,710,249
Ensembl chr20:1,700,905...1,710,249 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in ISO
IEA		 (PMID:24399297)
GO_REF:0000107		 RGD
Ensembl		 PMID:24399297 GO_REF:0000107 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
G Usp17li ubiquitin specific peptidase 17-like I involved_in ISO (PMID:20368735) RGD PMID:20368735 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IBA		 (PMID:30193849)
PMID:21873635		 RGD PMID:30193849 PMID:21873635 RGD:13792537 NCBI chr 3:140,872,460...140,875,292
Ensembl chr 3:140,872,460...140,882,408 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (MGI:5775261|PMID:25848864) RGD PMID:25848864 MGI:5775261 NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain involved_in ISO
IEA		 (PMID:22423966)
GO_REF:0000107		 RGD
Ensembl		 PMID:22423966 GO_REF:0000107 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) RGD PMID:19865078 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) RGD PMID:16267105 MGI:5788395 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:26599367), (PMID:28471450)
(MGI:6162316|PMID:26599367)		 RGD PMID:26599367 PMID:28471450 MGI:6162316 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in ISO
ISS		 (PMID:28471450)
GO_REF:0000024		 RGD
UniProt		 PMID:28471450 GO_REF:0000024 NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr1 toll-like receptor 1 involved_in ISO ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949) RGD PMID:22198949 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:25204797)
GO_REF:0000107		 RGD
Ensembl		 PMID:25204797 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) RGD PMID:19865078 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (MGI:4359971|PMID:19734906) RGD PMID:19734906 MGI:4359971 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in IBA
ISO		 PMID:21873635
(MGI:5562517|PMID:23871208)
(PMID:23871208)		 RGD PMID:23871208 PMID:21873635 MGI:5562517, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (MGI:4943396|PMID:17322885) RGD PMID:17322885 MGI:4943396 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Trim3 tripartite motif-containing 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:32878999)		 Ensembl
RGD		 PMID:32878999 GO_REF:0000107 NCBI chr 1:159,950,921...159,973,600
Ensembl chr 1:159,944,908...159,973,600 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IBA		 (PMID:25736436)
PMID:21873635
(MGI:5688815|PMID:25736436)		 RGD PMID:25736436 PMID:21873635 MGI:5688815, RGD:13792537 NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISS
ISO		 GO_REF:0000024
(MGI:5645195|PMID:24380872)		 UniProt
RGD		 PMID:24380872 GO_REF:0000024 MGI:5645195 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:18622013) RGD PMID:18622013 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) RGD PMID:16267105 MGI:5788395 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ifi35 interferon-induced protein 35 involved_in ISO (PMID:29038465) RGD PMID:29038465 NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA		 (PMID:11528597)
GO_REF:0000107		 RGD
Ensembl		 PMID:11528597 GO_REF:0000107 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6694429|PMID:25860173)		 UniProt
RGD		 PMID:25860173 GO_REF:0000024 MGI:6694429 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO (PMID:18511497) RGD PMID:18511497 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (MGI:4359971|PMID:19734906) RGD PMID:19734906 MGI:4359971 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO
IBA		 (PMID:23871208)
(MGI:5562517|PMID:23871208)
PMID:21873635		 RGD PMID:23871208 PMID:21873635 MGI:5562517, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184)
(PMID:22685567)		 RGD PMID:19412184 PMID:22685567 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) RGD PMID:19509286 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in ISO
IBA		 (PMID:25736436)
PMID:21873635
(MGI:5688815|PMID:25736436)		 RGD PMID:25736436 PMID:21873635 MGI:5688815, RGD:13792537 NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775 		JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO (PMID:28593998) RGD PMID:28593998 NCBI chr19:39,496,414...39,581,600
Ensembl chr19:39,496,527...39,580,969 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in IBA
ISO		 PMID:21873635
(MGI:5562517|PMID:23871208)		 RGD PMID:23871208 PMID:21873635 MGI:5562517, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:4943343|PMID:21435586)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21435586 GO_REF:0000024 GO_REF:0000107 MGI:4943343 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:4848237|PMID:21045126), (MGI:6357091|PMID:25238095)
GO_REF:0000024
(PMID:25238095), (PMID:32433612)		 Ensembl
RGD
UniProt		 PMID:21045126 PMID:25238095 PMID:32433612 GO_REF:0000024 GO_REF:0000107 MGI:4848237 MGI:6357091 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) RGD PMID:32433612 NCBI chr  X:50,403,962...50,423,141
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO
IBA		 (PMID:25848864)
(MGI:5775261|PMID:25848864)
PMID:21873635		 RGD PMID:25848864 PMID:21873635 MGI:5775261, RGD:13792537 NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:30341167) RGD PMID:30341167 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:32433612)		 Ensembl
UniProt
RGD		 PMID:32433612 GO_REF:0000024 GO_REF:0000107 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) RGD PMID:32433612 NCBI chr  X:50,403,962...50,423,141
Ensembl chr  X:50,361,248...50,423,269 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in IBA
ISO		 PMID:21873635
(MGI:5562517|PMID:23871208)		 RGD PMID:23871208 PMID:21873635 MGI:5562517, RGD:13792537 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:4943343|PMID:21435586)		 UniProt
Ensembl
RGD		 PMID:21435586 GO_REF:0000024 GO_REF:0000107 MGI:4943343 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Rtn4 reticulon 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6274965|PMID:25917084)		 UniProt
Ensembl
RGD		 PMID:25917084 GO_REF:0000024 GO_REF:0000107 MGI:6274965 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO
ISS
IEA		 (PMID:25238095)
GO_REF:0000024
(MGI:4848237|PMID:21045126), (MGI:6278628|PMID:21277849), (MGI:6357091|PMID:25238095)
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:21045126 PMID:21277849 PMID:25238095 GO_REF:0000024 GO_REF:0000107 MGI:4848237 MGI:6278628 MGI:6357091 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (MGI:3828189|PMID:18931679) RGD PMID:18931679 MGI:3828189 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 involved_in ISO (MGI:5775261|PMID:25848864) RGD PMID:25848864 MGI:5775261 NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrch4 leucine rich repeats and calponin homology domain containing 4 involved_in ISO (MGI:3615854|PMID:16449650) RGD PMID:16449650 MGI:3615854 NCBI chr12:19,057,582...19,072,573
Ensembl chr12:19,057,587...19,068,577 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5487531|PMID:20728433) RGD PMID:20728433 MGI:5487531 NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828 		JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in ISO (PMID:21109225) RGD PMID:21109225 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (MGI:5792628|PMID:27129230)
(PMID:24882218)		 RGD PMID:24882218 PMID:27129230 MGI:5792628 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (MGI:3718275|PMID:17618271) RGD PMID:17618271 MGI:3718275 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 acts_upstream_of_or_within ISO (MGI:3718275|PMID:17618271) RGD PMID:17618271 MGI:3718275 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor acts_upstream_of_or_within ISO (MGI:5432265|PMID:22745163) RGD PMID:22745163 MGI:5432265 NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16127453), (PMID:20451243) RGD PMID:16127453 PMID:20451243 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5583923|PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO (PMID:20061403) RGD PMID:20061403 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO (PMID:34160127) RGD PMID:34160127 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
IEA
ISS		 (PMID:28273161)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28273161 GO_REF:0000024 GO_REF:0000107 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA		 (PMID:23910378)
GO_REF:0000107
(MGI:6827194|PMID:23910378)		 RGD
Ensembl		 PMID:23910378 GO_REF:0000107 MGI:6827194 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:5792628 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Trim41 tripartite motif-containing 41 involved_in ISO (PMID:29760876) RGD PMID:29760876 NCBI chr10:33,175,213...33,186,472
Ensembl chr10:33,175,213...33,186,694 		JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (PMID:29426904)
(MGI:6119245|PMID:29426904)		 RGD PMID:29426904 MGI:6119245 NCBI chr12:19,544,913...19,567,324
Ensembl chr12:19,551,521...19,567,462 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218)
(MGI:5645191|PMID:24882218)		 RGD PMID:24882218 MGI:5645191 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked involved_in ISO (PMID:31534008) RGD PMID:31534008 NCBI chr  X:15,123,620...15,126,855
Ensembl chr  X:15,124,596...15,125,912 		JBrowse link
G Usp29 ubiquitin specific peptidase 29 involved_in ISO (MGI:6761183|PMID:32457395) RGD PMID:32457395 MGI:6761183 NCBI chr 1:66,874,216...67,097,731
Ensembl chr 1:66,874,017...67,097,686 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:19399181)
GO_REF:0000107		 RGD
Ensembl		 PMID:19399181 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000002
(MGI:3718275|PMID:17618271)
PMID:21873635		 InterPro
RGD		 PMID:17618271 PMID:21873635 GO_REF:0000002 MGI:3718275, RGD:13792537 NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
positive regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (MGI:3807609|PMID:18641331) RGD PMID:18641331 MGI:3807609 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:16888103)
(MGI:3656111|PMID:16888103)		 RGD PMID:16888103 MGI:3656111 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:2176946|MGI:3511276 (MGI:3798012|PMID:18339625) RGD PMID:18339625 MGI:3798012 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO (PMID:20061403), (PMID:20639463) RGD PMID:20061403 PMID:20639463 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO
IBA		 (PMID:27796300)
PMID:21873635
(MGI:5905929|PMID:27796300)		 RGD PMID:27796300 PMID:21873635 MGI:5905929, RGD:13792537 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Txk TXK tyrosine kinase involved_in ISO (PMID:11859127) RGD PMID:11859127 NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448 		JBrowse link
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec2d C-type lectin domain family 2, member D acts_upstream_of_or_within ISO MGI:107539 (MGI:2682492|PMID:12858173), (MGI:3041277|PMID:14990792), (MGI:3849756|PMID:19535641) RGD PMID:12858173 PMID:14990792 PMID:19535641 MGI:2682492 MGI:3041277 MGI:3849756 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937), (PMID:9754572) RGD PMID:9754572 PMID:25631937 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 NOT|involved_in ISO (PMID:18502829)
(PMID:18502829), (PMID:8839770)		 RGD PMID:8839770 PMID:18502829 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Serpinb3a serpin family B member 3A involved_in ISO (PMID:21857942) RGD PMID:21857942 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985 		JBrowse link
G Serpinb9 serpin family B member 9 involved_in ISO (PMID:21795594) RGD PMID:21795594 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member IMP RGD PMID:8120379 RGD:2312378 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407 		JBrowse link
regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfh complement factor H involved_in ISO (PMID:20378178), (PMID:28671664) RGD PMID:20378178 PMID:28671664 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir708 microRNA 708 involved_in ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:150,599,876...150,599,963
Ensembl chr 1:150,599,876...150,599,963 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3691368|PMID:17018642)		 UniProt
RGD		 PMID:17018642 GO_REF:0000024 MGI:3691368 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (MGI:3575992|PMID:15800576) RGD PMID:15800576 MGI:3575992 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf7 interferon regulatory factor 7 involved_in ISO (MGI:3575992|PMID:15800576) RGD PMID:15800576 MGI:3575992 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klrb1 killer cell lectin like receptor B1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:162,456,294...162,474,989
Ensembl chr 4:162,456,294...162,474,989 		JBrowse link
G Klrb1a killer cell lectin like receptor B1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675 		JBrowse link
G Klrb1b killer cell lectin like receptor B1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:161,948,259...161,961,537
Ensembl chr 4:161,890,577...161,961,675 		JBrowse link
G Klrb1c killer cell lectin like receptor B1C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:162,380,773...162,394,688
Ensembl chr 4:162,381,602...162,393,786 		JBrowse link
G Lep leptin involved_in ISS
ISO		 GO_REF:0000024
(PMID:12504075)		 UniProt
RGD		 PMID:12504075 GO_REF:0000024 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Nkr-p1c killer cell lectin-like receptor subfamily B member involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 involved_in ISO (PMID:11062502) RGD PMID:11062502 NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243 		JBrowse link
regulation of natural killer cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:18448674) RGD PMID:18448674 NCBI chr20:4,870,939...4,910,183 JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5432942|PMID:22801494)		 UniProt
RGD		 PMID:22801494 GO_REF:0000024 MGI:5432942 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (MGI:5562512|PMID:23892723) RGD PMID:23892723 MGI:5562512 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a2 solute carrier family 15 member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6192142|PMID:29784761)		 UniProt
RGD		 PMID:29784761 GO_REF:0000024 MGI:6192142 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6192142|PMID:29784761)		 UniProt
RGD		 PMID:29784761 GO_REF:0000024 MGI:6192142 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncf1 neutrophil cytosolic factor 1 IMP RGD PMID:21275845 RGD:41404729 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
regulation of response to type II interferon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO (PMID:16809771) RGD PMID:16809771 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:27824081) RGD PMID:27824081 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flot2 flotillin 2 NOT|involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Hcfc2 host cell factor C2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:5445585 (MGI:5923623|PMID:28970238)
GO_REF:0000107		 RGD
Ensembl		 PMID:28970238 GO_REF:0000107 MGI:5923623 NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:37158982) RGD PMID:37158982 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6270783|PMID:27219021) RGD PMID:27219021 MGI:6270783 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6270783|PMID:27219021) RGD PMID:27219021 MGI:6270783 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Flot1 flotillin 1 NOT|involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO
IEA		 (PMID:19289601)
GO_REF:0000107		 RGD
Ensembl		 PMID:19289601 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695864|PMID:31134514) RGD PMID:31134514 MGI:6695864 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:23857366) RGD PMID:23857366 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
regulation of toll-like receptor signaling pathway term browser