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Gene: TNIP2 (TNFAIP3 interacting protein 2) Homo sapiens
Symbol: TNIP2
Name: TNFAIP3 interacting protein 2
Description: Exhibits polyubiquitin modification-dependent protein binding activity and protein kinase binding activity. Involved in negative regulation of endothelial cell apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A20-binding inhibitor of NF-kappa-B activation 2; A20-binding inhibitor of NF-kappaB activation-2; ABIN2; DKFZp434J1313; fetal liver LKB1-interacting protein; FLIP1; KLIP; MGC4289; TNFAIP3-interacting protein 2
Mus musculus (house mouse) : Tnip2 (TNFAIP3 interacting protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tnip2 (TNFAIP3 interacting protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnip2 (TNFAIP3 interacting protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TNIP2 (TNFAIP3 interacting protein 2)
Canis lupus familiaris (dog) : TNIP2 (TNFAIP3 interacting protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnip2 (TNFAIP3 interacting protein 2)
Sus scrofa (pig) : TNIP2 (TNFAIP3 interacting protein 2)
Chlorocebus sabaeus (African green monkey) : TNIP2 (TNFAIP3 interacting protein 2)
Heterocephalus glaber (naked mole-rat) : Tnip2 (TNFAIP3 interacting protein 2)
more info ...
Related Pseudogenes: TNIP2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl42,741,648 - 2,756,342 (-)EnsemblGRCh38hg38GRCh38
GRCh3842,741,648 - 2,756,336 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3742,743,387 - 2,758,103 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3642,713,185 - 2,727,859 (-)NCBINCBI36hg18NCBI36
Build 3442,780,592 - 2,795,267NCBI
Celera42,654,688 - 2,669,415 (-)NCBI
Cytogenetic Map4p16.3NCBI
HuRef42,682,483 - 2,696,862 (-)NCBIHuRef
CHM1_142,741,351 - 2,756,073 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TNIP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317070
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.