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Gene: CXorf21 (chromosome X open reading frame 21) Homo sapiens
Symbol: CXorf21
Name: chromosome X open reading frame 21
Description: Involved in regulation of lysosomal lumen pH. Localizes to the cell; INTERACTS WITH aflatoxin B1; antirheumatic drug; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5430427O19Rik; FLJ11577; hypothetical protein LOC80231; uncharacterized protein CXorf21
Mus musculus (house mouse) : 5430427O19Rik (RIKEN cDNA 5430427O19 gene)  MGI  Alliance
Rattus norvegicus (Norway rat) : RGD1565785 (similar to chromosome X open reading frame 21)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102017498 (chromosome unknown open reading frame, human CXorf21)
Pan paniscus (bonobo/pygmy chimpanzee) : CXHXorf21 (chromosome X CXorf21 homolog)
Canis lupus familiaris (dog) : CXHXorf21 (chromosome X CXorf21 homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : CUNHXorf21 (chromosome unknown CXorf21 homolog)
Sus scrofa (pig) : CXHXorf21 (chromosome X CXorf21 homolog)
Chlorocebus sabaeus (green monkey) : CXHXorf21 (chromosome X open reading frame, human CXorf21)
Heterocephalus glaber (naked mole-rat) : CUNHXorf21 (chromosome unknown CXorf21 homolog)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX30,558,809 - 30,577,766 (-)Ensembl
GRCh38X30,558,809 - 30,577,766 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X30,576,941 - 30,596,033 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,486,862 - 30,505,835 (-)NCBINCBI36hg18NCBI36
Build 34X30,336,597 - 30,355,571NCBI
CeleraX34,698,462 - 34,717,597 (-)NCBI
Cytogenetic MapXp21.2NCBI
HuRefX28,314,203 - 28,333,300 (-)NCBIHuRef
CHM1_1X30,607,829 - 30,626,921 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CXorf21
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347440
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.