Gene: KCNK6 (potassium two pore domain channel subfamily K member 6) Homo sapiens
Symbol: KCNK6
Name: potassium two pore domain channel subfamily K member 6
Description: This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ12282; inward rectifying potassium channel protein TWIK-2; K2p6.1; K2P6.1 potassium channel; KCNK8; potassium channel subfamily K member 6; potassium channel, subfamily k, member 6 (twik-2); potassium channel, two pore domain subfamily K, member 6; TOSS; TWIK-2; TWIK-originated similarity sequence; TWIK-originated sodium similarity sequence; TWIK2
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381938,319,844 - 38,329,014 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371938,810,484 - 38,819,654 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361943,502,322 - 43,511,494 (+)NCBINCBI36hg18NCBI36
Build 341943,502,323 - 43,511,487NCBI
Celera1935,612,720 - 35,621,891 (+)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1935,258,112 - 35,267,183 (+)NCBIHuRef
CHM1_11938,810,843 - 38,820,013 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNK6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735903
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-05-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.