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Gene: TSPAN6 (tetraspanin 6) Homo sapiens
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Symbol: TSPAN6
Name: tetraspanin 6
Description: Involved in negative regulation of NIK/NF-kappaB signaling and negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway. Localizes to the extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A15 homolog; putative NF-kappa-B-activating protein 321; T245; tetraspan TM4SF; tetraspanin TM4-D; tetraspanin-6; TM4SF6; transmembrane 4 superfamily member 6; TSPAN-6
Orthologs:
Mus musculus (house mouse) : Tspan6 (tetraspanin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tspan6 (tetraspanin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tspan6 (tetraspanin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TSPAN6 (tetraspanin 6)
Canis lupus familiaris (dog) : TSPAN6 (tetraspanin 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tspan6 (tetraspanin 6)
Sus scrofa (pig) : TSPAN6 (tetraspanin 6)
Chlorocebus sabaeus (African green monkey) : TSPAN6 (tetraspanin 6)
Heterocephalus glaber (naked mole-rat) : Tspan6 (tetraspanin 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX100,627,108 - 100,639,991 (-)Ensembl
GRCh38X100,627,108 - 100,637,104 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X99,882,105 - 99,892,101 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X99,770,451 - 99,778,450 (-)NCBINCBI36hg18NCBI36
Build 34X99,689,939 - 99,697,939NCBI
CeleraX100,402,531 - 100,410,530 (-)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX89,659,381 - 89,692,021 (-)NCBIHuRef
CHM1_1X99,774,986 - 99,784,982 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TSPAN6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347181
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.