NR1H4 (nuclear receptor subfamily 1 group H member 4) - Rat Genome Database

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Gene: NR1H4 (nuclear receptor subfamily 1 group H member 4) Homo sapiens
Analyze
Symbol: NR1H4
Name: nuclear receptor subfamily 1 group H member 4
RGD ID: 734103
HGNC Page HGNC
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; bile acid receptor activity; and chenodeoxycholic acid binding activity. Involved in several processes, including cellular response to lipid; cellular triglyceride homeostasis; and regulation of gene expression. Acts upstream of or within negative regulation of very-low-density lipoprotein particle remodeling and positive regulation of transcription, DNA-templated. Located in euchromatin. Part of receptor complex. Implicated in extrahepatic cholestasis; hepatocellular carcinoma; and progressive familial intrahepatic cholestasis 5. Biomarker of hepatocellular carcinoma; non-alcoholic steatohepatitis; and primary biliary cholangitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BAR; bile acid receptor; farnesoid X nuclear receptor; farnesoid X receptor; farnesoid X-activated receptor; farnesol receptor HRR-1; FXR; HRR-1; HRR1; MGC163445; nuclear receptor subfamily 1, group H, member 4; PFIC5; retinoid X receptor-interacting protein 14; RIP14; RXR-interacting protein 14
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12100,473,708 - 100,564,414 (+)EnsemblGRCh38hg38GRCh38
GRCh3812100,473,866 - 100,564,414 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712100,867,644 - 100,958,192 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361299,391,810 - 99,481,774 (+)NCBINCBI36hg18NCBI36
Build 341299,370,146 - 99,460,111NCBI
Celera12100,532,992 - 100,622,995 (+)NCBI
Cytogenetic Map12q23.1NCBI
HuRef1297,928,334 - 98,018,410 (+)NCBIHuRef
CHM1_112100,833,597 - 100,923,679 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(S)-colchicine  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
22,23-dihydroavermectin B1a  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,6-diaminoacridine  (EXP)
3-chloropropane-1,2-diol  (ISO)
3alpha-hydroxy-5beta-pregnan-20-one  (ISO)
4'-epidoxorubicin  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (EXP)
5-aza-2'-deoxycytidine  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (EXP)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
9-aminoacridine  (EXP)
abamectin  (EXP)
acadesine  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (EXP)
AICA ribonucleotide  (ISO)
albendazole  (EXP)
albendazole S-oxide  (EXP)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-linolenic acid  (EXP)
alvocidib  (EXP)
ammonium chloride  (ISO)
angelicin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
apigenin  (EXP)
arachidonic acid  (EXP)
arjunolic acid  (ISO)
arotinoid acid  (EXP)
arsenite(3-)  (ISO)
atazanavir sulfate  (EXP)
benazepril  (EXP)
benidipine  (EXP)
benomyl  (EXP)
benzo[a]pyrene  (EXP)
beta-D-glucosamine  (ISO)
beta-hexachlorocyclohexane  (EXP,ISO)
beta-naphthoflavone  (EXP,ISO)
bezafibrate  (EXP,ISO)
bifenthrin  (EXP)
biochanin A  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
Boldine  (ISO)
bortezomib  (EXP)
bosentan  (EXP)
butachlor  (EXP)
butanal  (EXP)
carbendazim  (EXP)
carbon nanotube  (ISO)
chenodeoxycholic acid  (EXP,ISO)
chlorpromazine  (ISO)
cholanic acid  (EXP)
cholate  (EXP)
cholesterol  (EXP,ISO)
cholic acid  (EXP,ISO)
chrysin  (EXP)
ciclobendazole  (EXP)
cilnidipine  (EXP)
cisplatin  (EXP)
citric acid  (ISO)
clevidipine  (EXP)
clofibrate  (ISO)
clofibric acid  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
corilagin  (ISO)
Cyclopamine  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP)
cyhalothrin  (EXP)
cypermethrin  (EXP)
daunorubicin  (EXP)
DDE  (EXP)
deoxycholic acid  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (EXP)
digoxin  (EXP)
dihydroartemisinin  (EXP,ISO)
dimethyl sulfoxide  (ISO)
Diosbulbin B  (ISO)
dioscin  (ISO)
diosgenin  (ISO)
Diphenadione  (EXP)
dipyridamole  (EXP)
dobutamine  (EXP)
Doramectin  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
emamectin  (EXP)
emetine  (EXP)
emodin  (ISO)
endosulfan  (ISO)
enilconazole  (ISO)
eprinomectin  (EXP)
ethacridine  (EXP)
ethanol  (EXP,ISO)
ethylestrenol  (EXP)
farnesol  (EXP)
felodipine  (EXP)
fenbendazole  (EXP)
fenofibrate  (EXP,ISO)
fenvalerate  (EXP)
Fexaramine  (EXP)
flucythrinate  (EXP)
fluoranthene  (ISO)
fluoxastrobin  (EXP)
fluvalinate  (EXP)
fulvestrant  (EXP,ISO)
furan  (ISO)
gallocatechin  (EXP)
Geniposide  (ISO)
genistein  (EXP,ISO)
Gentiopicrin  (ISO)
ginsenoside Rg1  (ISO)
glafenine  (ISO)
glyburide  (ISO)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
glycyrrhetinic acid  (ISO)
griseofulvin  (EXP)
guggulsterone  (EXP,ISO)
GW 3965  (ISO)
GW 4064  (EXP,ISO)
GW 7647  (EXP)
hexadecanoic acid  (EXP,ISO)
high-density lipoprotein cholesterol  (ISO)
hydrogen peroxide  (EXP)
ibuprofen  (ISO)
idarubicin  (EXP)
imazamox  (EXP)
imazapyr  (EXP)
Imazethapyr  (EXP)
isoniazide  (EXP,ISO)
isoprenaline  (ISO)
isotretinoin  (EXP)
Isradipine  (EXP)
ivermectin  (EXP,ISO)
juvenile hormone III  (EXP)
kadethrin  (EXP)
ketoconazole  (EXP)
lacidipine  (EXP)
lercanidipine  (EXP)
lipopolysaccharide  (ISO)
lithocholic acid  (EXP,ISO)
malic acid  (ISO)
manidipine  (EXP)
mebendazole  (EXP)
menadione  (EXP)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxsalen  (ISO)
methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate  (EXP)
methylmercury chloride  (EXP)
milbemycin  (EXP)
mitomycin C  (EXP)
monascin  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
montelukast  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalenes  (EXP)
nefazodone  (EXP,ISO)
nemorubicin  (EXP)
Nicardipine  (EXP)
nifedipine  (EXP)
nimesulide  (ISO)
nimodipine  (EXP)
nisoldipine  (EXP)
nitrendipine  (EXP)
nitrofen  (ISO)
nocodazole  (EXP)
obeticholic acid  (EXP,ISO)
oleanolic acid  (ISO)
oleic acid  (EXP)
oxfendazole  (EXP)
ozone  (ISO)
papaverine  (EXP)
paracetamol  (EXP,ISO)
pentamidine  (EXP)
pentanal  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (EXP,ISO)
phenethyl caffeate  (ISO)
phenobarbital  (ISO)
phenothrin  (EXP)
picoxystrobin  (EXP)
picropodophyllotoxin  (EXP)
Pirarubicin  (EXP)
pirinixic acid  (ISO)
platycodin D  (EXP)
podophyllotoxin  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (EXP)
psoralen  (ISO)
pyrazinecarboxamide  (ISO)
quercetin  (EXP)
quinolines  (EXP)
resveratrol  (ISO)
rifaximin  (EXP)
ritonavir  (EXP)
rosuvastatin  (ISO)
rotenone  (EXP)
Salidroside  (ISO)
Selamectin  (EXP)
senecionine  (ISO)
silibinin  (ISO)
silicon dioxide  (EXP)
simvastatin  (ISO)
sirolimus  (EXP)
sodium arsenite  (EXP)
stigmasterol  (ISO)
streptozocin  (ISO)
tamibarotene  (EXP)
tamoxifen  (ISO)
taurine  (ISO)
tauro-beta-muricholic acid  (ISO)
taurocholic acid  (EXP,ISO)
taurodeoxycholic acid  (EXP)
temozolomide  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trifloxystrobin  (EXP)
Triptolide  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
uranium atom  (ISO)
urethane  (EXP)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (EXP,ISO)
vincaleukoblastine  (EXP)
vincristine  (EXP)
vinorelbine  (EXP)
Yangonin  (EXP,ISO)
zinc acetate  (ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
bile acid and bile salt transport  (ISO)
bile acid metabolic process  (ISO)
bile acid signaling pathway  (IBA,ISO,ISS,TAS)
cell differentiation  (IBA)
cell-cell junction assembly  (ISO)
cellular glucose homeostasis  (ISO)
cellular response to bile acid  (IDA)
cellular response to fatty acid  (IDA)
cellular response to lipopolysaccharide  (ISO)
cellular response to organonitrogen compound  (ISS)
cellular response to xenobiotic stimulus  (ISO)
cellular triglyceride homeostasis  (IDA)
cholesterol homeostasis  (ISO)
defense response to bacterium  (ISO)
digestive tract development  (ISO)
fatty acid homeostasis  (ISO)
glucose homeostasis  (ISO)
hepatocyte proliferation  (ISO)
histone H3-R17 methylation  (IDA)
inflammatory response  (IEA)
innate immune response  (IEA)
intracellular bile acid receptor signaling pathway  (IDA)
intracellular receptor signaling pathway  (ISS)
leukocyte migration involved in inflammatory response  (ISO)
lipid localization  (ISO)
liver regeneration  (ISO)
negative regulation of apoptotic process  (IDA)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of I-kappaB kinase/NF-kappaB signaling  (IDA)
negative regulation of inflammatory response  (IBA)
negative regulation of interferon-gamma production  (IDA)
negative regulation of interleukin-1 production  (ISO)
negative regulation of interleukin-2 production  (ISO)
negative regulation of interleukin-6 production  (ISO)
negative regulation of monocyte chemotactic protein-1 production  (ISO)
negative regulation of NF-kappaB transcription factor activity  (ISO)
negative regulation of transcription by RNA polymerase II  (IBA,ISO,ISS)
negative regulation of triglyceride biosynthetic process  (ISO)
negative regulation of tumor necrosis factor production  (IDA)
negative regulation of tumor necrosis factor-mediated signaling pathway  (ISO)
negative regulation of very-low-density lipoprotein particle remodeling  (IDA)
nitrogen catabolite activation of transcription from RNA polymerase II promoter  (IC)
Notch signaling pathway  (ISO)
positive regulation of adipose tissue development  (ISO)
positive regulation of ammonia assimilation cycle  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of glutamate metabolic process  (ISS)
positive regulation of insulin receptor signaling pathway  (ISO)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
positive regulation of interleukin-17 production  (IDA)
positive regulation of phosphatidic acid biosynthetic process  (IDA)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IMP,ISO)
positive regulation of transcription, DNA-templated  (IDA)
regulation of bile acid biosynthetic process  (TAS)
regulation of bile acid secretion  (ISO)
regulation of carbohydrate metabolic process  (ISO)
regulation of cholesterol metabolic process  (TAS)
regulation of gene expression  (ISO)
regulation of insulin secretion involved in cellular response to glucose stimulus  (IDA)
regulation of lipid storage  (ISO)
regulation of low-density lipoprotein particle clearance  (IDA)
regulation of transcription by RNA polymerase II  (IDA,ISO)
regulation of transcription, DNA-templated  (IEA,IMP)
regulation of urea metabolic process  (ISS)
response to 17alpha-ethynylestradiol  (ISO)
response to cholesterol  (ISO)
response to ethanol  (ISO)
response to fenofibrate  (ISO)
response to glucose  (ISO)
response to lipopolysaccharide  (ISO)
response to norepinephrine  (ISO)
response to nutrient levels  (ISO)
response to organic cyclic compound  (ISO)
response to xenobiotic stimulus  (ISO)
toll-like receptor 4 signaling pathway  (IDA)
toll-like receptor 9 signaling pathway  (ISO)
triglyceride homeostasis  (ISO)

Cellular Component
chromatin  (IC,ISA)
euchromatin  (IDA)
nucleoplasm  (TAS)
nucleus  (IEA,ISO)
receptor complex  (IDA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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Additional References at PubMed
PMID:7760852   PMID:8835541   PMID:9223286   PMID:10334992   PMID:10334993   PMID:10360171   PMID:10968783   PMID:11030331   PMID:11030332   PMID:11030617   PMID:11136553   PMID:11733517  
PMID:11988537   PMID:12004058   PMID:12062799   PMID:12477932   PMID:12554753   PMID:12660231   PMID:12718892   PMID:12718893   PMID:12754200   PMID:12761213   PMID:12806625   PMID:12815072  
PMID:12891557   PMID:12917342   PMID:14527955   PMID:14684751   PMID:14701856   PMID:14988830   PMID:14990788   PMID:15187081   PMID:15202934   PMID:15342685   PMID:15454728   PMID:15471871  
PMID:15564327   PMID:15590640   PMID:15604093   PMID:15604525   PMID:15721319   PMID:15817812   PMID:15911693   PMID:16012168   PMID:16037943   PMID:16197915   PMID:16219912   PMID:16251721  
PMID:16269519   PMID:16344560   PMID:16410358   PMID:16423920   PMID:16460270   PMID:16494845   PMID:16614213   PMID:16778009   PMID:16844773   PMID:17047076   PMID:17054793   PMID:17071613  
PMID:17241392   PMID:17272748   PMID:17333335   PMID:17474147   PMID:17495603   PMID:17507182   PMID:17519356   PMID:17681172   PMID:17876519   PMID:17895379   PMID:17931734   PMID:17988216  
PMID:18029909   PMID:18391212   PMID:18436567   PMID:18514055   PMID:18563553   PMID:18621523   PMID:18660489   PMID:18668687   PMID:18676680   PMID:18755856   PMID:18768987   PMID:18769028  
PMID:18779653   PMID:18842595   PMID:18927204   PMID:18972560   PMID:18978041   PMID:19027009   PMID:19028791   PMID:19059462   PMID:19072826   PMID:19105941   PMID:19150878   PMID:19159286  
PMID:19170196   PMID:19195631   PMID:19228886   PMID:19245866   PMID:19274049   PMID:19393742   PMID:19410460   PMID:19556342   PMID:19586769   PMID:19625176   PMID:19692168   PMID:19833092  
PMID:19864602   PMID:19883617   PMID:19910507   PMID:19913569   PMID:19948975   PMID:19996107   PMID:20026603   PMID:20095622   PMID:20189675   PMID:20338915   PMID:20346360   PMID:20373033  
PMID:20399894   PMID:20447400   PMID:20827719   PMID:20855565   PMID:20883210   PMID:21242261   PMID:21296199   PMID:21323950   PMID:21330447   PMID:21364590   PMID:21431940   PMID:21532585  
PMID:21596433   PMID:21619550   PMID:21633855   PMID:21757002   PMID:21856289   PMID:21862343   PMID:21873635   PMID:21887309   PMID:21893226   PMID:21988803   PMID:22146319   PMID:22223860  
PMID:22252013   PMID:22265968   PMID:22266736   PMID:22285937   PMID:22345554   PMID:22446874   PMID:22474109   PMID:22550135   PMID:22558273   PMID:22561792   PMID:22609541   PMID:22632967  
PMID:22817871   PMID:22898327   PMID:22929053   PMID:22952826   PMID:22969091   PMID:23042943   PMID:23056173   PMID:23119029   PMID:23251605   PMID:23341777   PMID:23348121   PMID:23462506  
PMID:23507574   PMID:23519696   PMID:23530060   PMID:23546875   PMID:23620138   PMID:23640969   PMID:23703321   PMID:23767959   PMID:23784309   PMID:23861371   PMID:23916961   PMID:23928191  
PMID:24002920   PMID:24037988   PMID:24043304   PMID:24169962   PMID:24211198   PMID:24297698   PMID:24321096   PMID:24498169   PMID:24531544   PMID:24670636   PMID:25043081   PMID:25086996  
PMID:25138215   PMID:25198545   PMID:25242139   PMID:25257666   PMID:25363753   PMID:25383523   PMID:25383539   PMID:25400456   PMID:25496033   PMID:25596928   PMID:25655198   PMID:25675114  
PMID:26019035   PMID:26134028   PMID:26241054   PMID:26292095   PMID:26302777   PMID:26305715   PMID:26416445   PMID:26488943   PMID:26607331   PMID:26670557   PMID:26728993   PMID:26871637  
PMID:26888176   PMID:26899873   PMID:27045028   PMID:27109477   PMID:27138288   PMID:27251172   PMID:27471003   PMID:27596062   PMID:27738335   PMID:27758768   PMID:27846919   PMID:27853248  
PMID:28201649   PMID:28287408   PMID:28400119   PMID:28402278   PMID:28485172   PMID:28496032   PMID:28514442   PMID:28535186   PMID:28619996   PMID:28746779   PMID:28762281   PMID:28916388  
PMID:28970500   PMID:29377207   PMID:29771182   PMID:29921626   PMID:29929982   PMID:29958417   PMID:30013008   PMID:30106441   PMID:30176263   PMID:30206765   PMID:30275017   PMID:30354208  
PMID:30366773   PMID:30745168   PMID:30844798   PMID:30884797   PMID:30967475   PMID:31062417   PMID:31105019   PMID:31266946   PMID:31623375   PMID:31779647   PMID:31949131   PMID:32001246  
PMID:32296183   PMID:32299194   PMID:32581266   PMID:32597704   PMID:32650752   PMID:32678214   PMID:32712104   PMID:32807788   PMID:32846898   PMID:33029504   PMID:33029898   PMID:33568795  


Genomics

Comparative Map Data
NR1H4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12100,473,708 - 100,564,414 (+)EnsemblGRCh38hg38GRCh38
GRCh3812100,473,866 - 100,564,414 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712100,867,644 - 100,958,192 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361299,391,810 - 99,481,774 (+)NCBINCBI36hg18NCBI36
Build 341299,370,146 - 99,460,111NCBI
Celera12100,532,992 - 100,622,995 (+)NCBI
Cytogenetic Map12q23.1NCBI
HuRef1297,928,334 - 98,018,410 (+)NCBIHuRef
CHM1_112100,833,597 - 100,923,679 (+)NCBICHM1_1
Nr1h4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391089,290,096 - 89,369,484 (-)NCBIGRCm39mm39
GRCm39 Ensembl1089,290,096 - 89,369,447 (-)Ensembl
GRCm381089,454,234 - 89,533,645 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1089,454,234 - 89,533,585 (-)EnsemblGRCm38mm10GRCm38
MGSCv371088,916,979 - 88,996,367 (-)NCBIGRCm37mm9NCBIm37
MGSCv361088,884,177 - 88,936,426 (-)NCBImm8
Celera1091,441,224 - 91,574,747 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1044.98NCBI
Nr1h4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2723,846,122 - 23,942,085 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl723,846,122 - 23,942,047 (-)Ensembl
Rnor_6.0730,003,429 - 30,162,095 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,003,429 - 30,162,056 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,170,397 - 30,214,796 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0730,104,960 - 30,107,142 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4726,189,759 - 26,307,061 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1726,210,029 - 26,327,332 (-)NCBI
Celera720,992,814 - 21,085,820 (-)NCBICelera
Cytogenetic Map7q13NCBI
Nr1h4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540536,160,049 - 36,237,751 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540536,160,360 - 36,236,258 (+)NCBIChiLan1.0ChiLan1.0
NR1H4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112101,457,885 - 101,548,058 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12101,457,885 - 101,548,058 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01298,052,778 - 98,144,085 (+)NCBIMhudiblu_PPA_v0panPan3
NR1H4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11539,497,313 - 39,608,120 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1539,536,290 - 39,608,116 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1539,876,387 - 39,987,365 (+)NCBI
ROS_Cfam_1.01540,161,103 - 40,272,109 (+)NCBI
UMICH_Zoey_3.11539,418,531 - 39,529,420 (+)NCBI
UNSW_CanFamBas_1.01539,525,061 - 39,636,033 (+)NCBI
UU_Cfam_GSD_1.01539,799,183 - 39,910,169 (+)NCBI
Nr1h4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494520,304,852 - 20,379,409 (-)NCBI
SpeTri2.0NW_00493649213,315,265 - 13,365,186 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR1H4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl583,604,288 - 83,684,604 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1583,607,222 - 83,732,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2587,754,914 - 87,828,507 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NR1H4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11195,792,428 - 95,877,989 (+)NCBI
ChlSab1.1 Ensembl1195,792,996 - 95,878,293 (+)Ensembl
Vero_WHO_p1.0NW_023666037149,156,310 - 149,247,016 (-)NCBI
Nr1h4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247507,222,306 - 7,303,809 (-)NCBI

Position Markers
D12S332  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,947,903 - 100,948,231UniSTSGRCh37
GRCh3712100,947,996 - 100,948,113UniSTSGRCh37
Build 361299,472,127 - 99,472,244RGDNCBI36
Celera12100,613,257 - 100,613,589UniSTS
Celera12100,613,350 - 100,613,467RGD
Cytogenetic Map12q23.1UniSTS
HuRef1298,008,770 - 98,008,887UniSTS
HuRef1298,008,677 - 98,009,009UniSTS
Marshfield Genetic Map12105.18UniSTS
Marshfield Genetic Map12105.18RGD
Genethon Genetic Map12106.6UniSTS
deCODE Assembly Map12111.99UniSTS
Stanford-G3 RH Map124181.0UniSTS
Whitehead-YAC Contig Map12 UniSTS
GeneMap99-G3 RH Map124127.0UniSTS
RH79063  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,905,173 - 100,905,383UniSTSGRCh37
Build 361299,429,304 - 99,429,514RGDNCBI36
Celera12100,570,486 - 100,570,696RGD
Cytogenetic Map12q23.1UniSTS
HuRef1297,965,957 - 97,966,167UniSTS
GeneMap99-GB4 RH Map12398.52UniSTS
SHGC-81175  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,914,964 - 100,915,241UniSTSGRCh37
Build 361299,439,095 - 99,439,372RGDNCBI36
Celera12100,580,277 - 100,580,554RGD
Cytogenetic Map12q23.1UniSTS
HuRef1297,975,751 - 97,976,028UniSTS
TNG Radiation Hybrid Map1249891.0UniSTS
G64580  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,931,184 - 100,931,355UniSTSGRCh37
Build 361299,455,315 - 99,455,486RGDNCBI36
Celera12100,596,498 - 100,596,669RGD
Cytogenetic Map12q23.1UniSTS
G64833  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,931,021 - 100,931,202UniSTSGRCh37
Build 361299,455,152 - 99,455,333RGDNCBI36
Celera12100,596,335 - 100,596,516RGD
Cytogenetic Map12q23.1UniSTS
HuRef1297,991,809 - 97,991,990UniSTS
PMC137182P6  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,950,305 - 100,950,469UniSTSGRCh37
Build 361299,474,436 - 99,474,600RGDNCBI36
Celera12100,615,663 - 100,615,827RGD
Cytogenetic Map12q23.1UniSTS
HuRef1298,011,083 - 98,011,247UniSTS
PMC219489P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,945,039 - 100,945,472UniSTSGRCh37
Build 361299,469,170 - 99,469,603RGDNCBI36
Celera12100,610,393 - 100,610,826RGD
Cytogenetic Map12q23.1UniSTS
HuRef1298,005,814 - 98,006,247UniSTS
PMC219489P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,944,917 - 100,945,472UniSTSGRCh37
Build 361299,469,048 - 99,469,603RGDNCBI36
Celera12100,610,271 - 100,610,826RGD
Cytogenetic Map12q23.1UniSTS
HuRef1298,005,692 - 98,006,247UniSTS
PMC219489P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,944,917 - 100,945,597UniSTSGRCh37
Build 361299,469,048 - 99,469,728RGDNCBI36
Celera12100,610,271 - 100,610,951RGD
Cytogenetic Map12q23.1UniSTS
HuRef1298,005,692 - 98,006,372UniSTS
NR1I2_2318  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,957,040 - 100,957,743UniSTSGRCh37
Build 361299,481,171 - 99,481,874RGDNCBI36
Celera12100,622,392 - 100,623,095RGD
HuRef1298,017,805 - 98,018,508UniSTS
SGC33913  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,957,395 - 100,957,520UniSTSGRCh37
Build 361299,481,526 - 99,481,651RGDNCBI36
Celera12100,622,747 - 100,622,872RGD
Cytogenetic Map12q23.1UniSTS
HuRef1298,018,160 - 98,018,285UniSTS
GeneMap99-GB4 RH Map12397.91UniSTS
Whitehead-RH Map12488.1UniSTS
AFM326tf5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,937,210 - 100,937,428UniSTSGRCh37
Build 361299,461,341 - 99,461,559RGDNCBI36
Celera12100,602,524 - 100,602,742RGD
Cytogenetic Map12q23.1UniSTS
HuRef1297,997,892 - 97,998,110UniSTS
Whitehead-RH Map12492.2UniSTS
NCBI RH Map12689.3UniSTS
D12S871  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,903,467 - 100,903,766UniSTSGRCh37
Build 361299,427,598 - 99,427,897RGDNCBI36
Celera12100,568,780 - 100,569,079RGD
Cytogenetic Map12q23.1UniSTS
HuRef1297,964,251 - 97,964,550UniSTS
Whitehead-RH Map12492.2UniSTS
Whitehead-YAC Contig Map12 UniSTS
NCBI RH Map12689.3UniSTS
RH15652  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712100,957,321 - 100,957,433UniSTSGRCh37
Build 361299,481,452 - 99,481,564RGDNCBI36
Celera12100,622,673 - 100,622,785RGD
Cytogenetic Map12q23.1UniSTS
HuRef1298,018,086 - 98,018,198UniSTS
GeneMap99-GB4 RH Map12396.38UniSTS
NCBI RH Map12689.3UniSTS
D12S332  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q23.1UniSTS
Stanford-G3 RH Map124181.0UniSTS
GeneMap99-G3 RH Map124127.0UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR421hsa-miR-421OncomiRDBexternal_infoNANA22446874
MIR421hsa-miR-421OncomiRDBexternal_infoNANA22146319

Predicted Target Of
Summary Value
Count of predictions:1428
Count of miRNA genes:589
Interacting mature miRNAs:654
Transcripts:ENST00000188403, ENST00000321046, ENST00000392986, ENST00000546380, ENST00000548621, ENST00000548884, ENST00000549996, ENST00000551184, ENST00000551379
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 218 2 663 430 120 431 1 6 229 124 4
Low 385 76 303 20 100 21 16 18 292 109 388 71 1 3 6
Below cutoff 1294 1323 317 78 692 6 1515 837 2205 36 590 743 72 405 1019 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_135146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006719719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011539042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB307699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC010200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF384555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF478445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF478446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY245533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC071778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX571749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA011411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA016827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ709175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT585226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U68233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000188403   ⟹   ENSP00000188403
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,503,360 - 100,563,642 (+)Ensembl
RefSeq Acc Id: ENST00000321046   ⟹   ENSP00000315442
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,473,916 - 100,563,511 (+)Ensembl
RefSeq Acc Id: ENST00000392986   ⟹   ENSP00000376712
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,473,866 - 100,564,414 (+)Ensembl
RefSeq Acc Id: ENST00000546380   ⟹   ENSP00000446760
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,473,955 - 100,505,766 (+)Ensembl
RefSeq Acc Id: ENST00000548621   ⟹   ENSP00000446584
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,474,002 - 100,505,796 (+)Ensembl
RefSeq Acc Id: ENST00000548884   ⟹   ENSP00000448506
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,473,708 - 100,564,413 (+)Ensembl
RefSeq Acc Id: ENST00000549996   ⟹   ENSP00000448978
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,473,916 - 100,563,511 (+)Ensembl
RefSeq Acc Id: ENST00000551184   ⟹   ENSP00000446861
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,503,453 - 100,505,824 (+)Ensembl
RefSeq Acc Id: ENST00000551379   ⟹   ENSP00000447149
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,503,360 - 100,563,489 (+)Ensembl
RefSeq Acc Id: ENST00000648861   ⟹   ENSP00000496908
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,473,951 - 100,563,867 (+)Ensembl
RefSeq Acc Id: ENST00000649582   ⟹   ENSP00000496824
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl12100,473,893 - 100,505,782 (+)Ensembl
RefSeq Acc Id: NM_001206977   ⟹   NP_001193906
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,473,866 - 100,564,414 (+)NCBI
GRCh3712100,867,486 - 100,957,645 (+)NCBI
HuRef1297,928,334 - 98,018,410 (+)ENTREZGENE
CHM1_112100,833,597 - 100,923,679 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206978   ⟹   NP_001193907
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,473,866 - 100,564,414 (+)NCBI
GRCh3712100,867,486 - 100,957,645 (+)NCBI
HuRef1297,928,334 - 98,018,410 (+)ENTREZGENE
CHM1_112100,833,597 - 100,923,679 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206979   ⟹   NP_001193908
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,473,866 - 100,564,414 (+)NCBI
GRCh3712100,867,486 - 100,957,645 (+)NCBI
HuRef1297,928,334 - 98,018,410 (+)ENTREZGENE
CHM1_112100,833,597 - 100,923,679 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206992   ⟹   NP_001193921
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,503,360 - 100,564,414 (+)NCBI
GRCh3712100,867,486 - 100,957,645 (+)NCBI
HuRef1297,928,334 - 98,018,410 (+)ENTREZGENE
CHM1_112100,863,188 - 100,923,679 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001206993   ⟹   NP_001193922
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,503,360 - 100,564,414 (+)NCBI
GRCh3712100,867,486 - 100,957,645 (+)NCBI
HuRef1297,928,334 - 98,018,410 (+)ENTREZGENE
CHM1_112100,863,188 - 100,923,679 (+)NCBI
Sequence:
RefSeq Acc Id: NM_005123   ⟹   NP_005114
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,473,866 - 100,564,414 (+)NCBI
GRCh3712100,867,486 - 100,957,645 (+)NCBI
Build 361299,391,810 - 99,481,774 (+)NCBI Archive
HuRef1297,928,334 - 98,018,410 (+)ENTREZGENE
CHM1_112100,833,597 - 100,923,679 (+)NCBI
Sequence:
RefSeq Acc Id: NR_135146
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,473,866 - 100,564,414 (+)NCBI
CHM1_112100,833,597 - 100,923,679 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006719719   ⟹   XP_006719782
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,503,359 - 100,536,968 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011539040   ⟹   XP_011537342
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,491,045 - 100,563,867 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011539041   ⟹   XP_011537343
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,502,962 - 100,563,867 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011539042   ⟹   XP_011537344
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,503,359 - 100,536,968 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001193906 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193907 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193908 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193921 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193922 (Get FASTA)   NCBI Sequence Viewer  
  NP_005114 (Get FASTA)   NCBI Sequence Viewer  
  XP_006719782 (Get FASTA)   NCBI Sequence Viewer  
  XP_011537342 (Get FASTA)   NCBI Sequence Viewer  
  XP_011537343 (Get FASTA)   NCBI Sequence Viewer  
  XP_011537344 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB08107 (Get FASTA)   NCBI Sequence Viewer  
  AAH71778 (Get FASTA)   NCBI Sequence Viewer  
  AAI30574 (Get FASTA)   NCBI Sequence Viewer  
  AAI44185 (Get FASTA)   NCBI Sequence Viewer  
  AAK60271 (Get FASTA)   NCBI Sequence Viewer  
  AAM53550 (Get FASTA)   NCBI Sequence Viewer  
  AAM53551 (Get FASTA)   NCBI Sequence Viewer  
  ADZ17382 (Get FASTA)   NCBI Sequence Viewer  
  BAG35798 (Get FASTA)   NCBI Sequence Viewer  
  BAH02290 (Get FASTA)   NCBI Sequence Viewer  
  BAH12398 (Get FASTA)   NCBI Sequence Viewer  
  BAH12409 (Get FASTA)   NCBI Sequence Viewer  
  CAE11874 (Get FASTA)   NCBI Sequence Viewer  
  EAW97638 (Get FASTA)   NCBI Sequence Viewer  
  EAW97639 (Get FASTA)   NCBI Sequence Viewer  
  EAW97640 (Get FASTA)   NCBI Sequence Viewer  
  Q96RI1 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001193906   ⟸   NM_001206977
- Peptide Label: isoform 1
- UniProtKB: Q96RI1 (UniProtKB/Swiss-Prot),   F1DAL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193908   ⟸   NM_001206979
- Peptide Label: isoform 1
- UniProtKB: Q96RI1 (UniProtKB/Swiss-Prot),   F1DAL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_005114   ⟸   NM_005123
- Peptide Label: isoform 2
- UniProtKB: Q96RI1 (UniProtKB/Swiss-Prot),   B6ZGS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193907   ⟸   NM_001206978
- Peptide Label: isoform 5
- UniProtKB: Q96RI1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193922   ⟸   NM_001206993
- Peptide Label: isoform 3
- UniProtKB: Q96RI1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193921   ⟸   NM_001206992
- Peptide Label: isoform 4
- UniProtKB: Q96RI1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006719782   ⟸   XM_006719719
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011537342   ⟸   XM_011539040
- Peptide Label: isoform X1
- UniProtKB: Q96RI1 (UniProtKB/Swiss-Prot),   F1DAL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011537343   ⟸   XM_011539041
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011537344   ⟸   XM_011539042
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSP00000496908   ⟸   ENST00000648861
RefSeq Acc Id: ENSP00000188403   ⟸   ENST00000188403
RefSeq Acc Id: ENSP00000496824   ⟸   ENST00000649582
RefSeq Acc Id: ENSP00000446760   ⟸   ENST00000546380
RefSeq Acc Id: ENSP00000315442   ⟸   ENST00000321046
RefSeq Acc Id: ENSP00000448506   ⟸   ENST00000548884
RefSeq Acc Id: ENSP00000446584   ⟸   ENST00000548621
RefSeq Acc Id: ENSP00000448978   ⟸   ENST00000549996
RefSeq Acc Id: ENSP00000376712   ⟸   ENST00000392986
RefSeq Acc Id: ENSP00000446861   ⟸   ENST00000551184
RefSeq Acc Id: ENSP00000447149   ⟸   ENST00000551379
Protein Domains
NR LBD   Nuclear receptor

Promoters
RGD ID:7225151
Promoter ID:EPDNEW_H18321
Type:initiation region
Name:NR1H4_1
Description:nuclear receptor subfamily 1 group H member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18322  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,473,866 - 100,473,926EPDNEW
RGD ID:7225153
Promoter ID:EPDNEW_H18322
Type:multiple initiation site
Name:NR1H4_2
Description:nuclear receptor subfamily 1 group H member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18321  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3812100,503,360 - 100,503,420EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001206979.2(NR1H4):c.658G>T (p.Ala220Ser) single nucleotide variant not provided [RCV000727990] Chr12:100534949 [GRCh38]
Chr12:100928727 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.1322T>C (p.Leu441Pro) single nucleotide variant not provided [RCV000729788] Chr12:100563380 [GRCh38]
Chr12:100957158 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.1174A>G (p.Ile392Val) single nucleotide variant not provided [RCV000728124] Chr12:100561980 [GRCh38]
Chr12:100955758 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.345C>T (p.Gly115=) single nucleotide variant not provided [RCV000728189] Chr12:100511043 [GRCh38]
Chr12:100904821 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.733-2A>G single nucleotide variant not provided [RCV000728282] Chr12:100536510 [GRCh38]
Chr12:100930288 [GRCh37]
Chr12:12q23.1
likely pathogenic
NM_001206979.2(NR1H4):c.725C>T (p.Ser242Leu) single nucleotide variant not provided [RCV000729580] Chr12:100535016 [GRCh38]
Chr12:100928794 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.1079-8C>T single nucleotide variant not provided [RCV000729133] Chr12:100561877 [GRCh38]
Chr12:100955655 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206992.1(NR1H4):c.92G>A (p.Ser31Asn) single nucleotide variant Malignant melanoma [RCV000070271] Chr12:100503479 [GRCh38]
Chr12:100897257 [GRCh37]
Chr12:99421388 [NCBI36]
Chr12:12q23.1
not provided
NM_001206977.1(NR1H4):c.1033C>T (p.Pro345Ser) single nucleotide variant Malignant melanoma [RCV000070272] Chr12:100540773 [GRCh38]
Chr12:100934551 [GRCh37]
Chr12:99458682 [NCBI36]
Chr12:12q23.1
not provided
GRCh38/hg38 12q23.1-23.2(chr12:97394550-101410225)x3 copy number gain See cases [RCV000137891] Chr12:97394550..101410225 [GRCh38]
Chr12:97788328..101804003 [GRCh37]
Chr12:96312459..100328134 [NCBI36]
Chr12:12q23.1-23.2
likely pathogenic
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12q21.33-24.11(chr12:91044318-109133210)x3 copy number gain See cases [RCV000142447] Chr12:91044318..109133210 [GRCh38]
Chr12:91438095..109571015 [GRCh37]
Chr12:89962226..108055398 [NCBI36]
Chr12:12q21.33-24.11
pathogenic
NM_001206979.2(NR1H4):c.526C>T (p.Arg176Ter) single nucleotide variant Cholestasis, progressive familial intrahepatic 1 [RCV000240831]|Cholestasis, progressive familial intrahepatic, 5 [RCV000239570] Chr12:100532538 [GRCh38]
Chr12:100926316 [GRCh37]
Chr12:12q23.1
pathogenic
NM_001206979.2(NR1H4):c.419_420insAAA (p.Asn140_Ala141insLys) insertion Cholestasis, progressive familial intrahepatic 1 [RCV000240839]|Cholestasis, progressive familial intrahepatic, 5 [RCV000239480] Chr12:100511115..100511116 [GRCh38]
Chr12:100904893..100904894 [GRCh37]
Chr12:12q23.1
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
NR1H4, 3-BP INS, 419AAA insertion Cholestasis, progressive familial intrahepatic, 5 [RCV000239480] Chr12:12q23.1 pathogenic
NR1H4, 31.7-KB DEL deletion Cholestasis, progressive familial intrahepatic, 5 [RCV000239533] Chr12:12q23.1 pathogenic
NR1H4, ARG176TER variation Cholestasis, progressive familial intrahepatic, 5 [RCV000239570]   pathogenic
NM_001206979.2(NR1H4):c.931+19A>C single nucleotide variant not specified [RCV000244740] Chr12:100537066 [GRCh38]
Chr12:100930844 [GRCh37]
Chr12:12q23.1
benign
NM_001206979.2(NR1H4):c.832-16T>A single nucleotide variant not specified [RCV000252111] Chr12:100536932 [GRCh38]
Chr12:100930710 [GRCh37]
Chr12:12q23.1
benign
NM_001206979.2(NR1H4):c.1245T>C (p.Leu415=) single nucleotide variant not provided [RCV000726961]|not specified [RCV000247357] Chr12:100563303 [GRCh38]
Chr12:100957081 [GRCh37]
Chr12:12q23.1
likely benign|conflicting interpretations of pathogenicity|uncertain significance
NM_001206979.2(NR1H4):c.-1G>T single nucleotide variant not specified [RCV000242576] Chr12:100493323 [GRCh38]
Chr12:100887101 [GRCh37]
Chr12:12q23.1
benign
Single allele deletion Cholestasis, progressive familial intrahepatic 1 [RCV000240814] Chr12:100492476..100524210 [GRCh38]
Chr12:100886254..100917988 [GRCh37]
Chr12:12q23.1
pathogenic
NM_001206979.2(NR1H4):c.518T>C (p.Met173Thr) single nucleotide variant not provided [RCV000886965]|not specified [RCV000303836] Chr12:100532530 [GRCh38]
Chr12:100926308 [GRCh37]
Chr12:12q23.1
likely benign
NM_001206979.2(NR1H4):c.107C>T (p.Pro36Leu) single nucleotide variant not provided [RCV000347594] Chr12:100510805 [GRCh38]
Chr12:100904583 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.893A>G (p.His298Arg) single nucleotide variant not provided [RCV000383408] Chr12:100537009 [GRCh38]
Chr12:100930787 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.18T>C (p.Asn6=) single nucleotide variant not provided [RCV000280134] Chr12:100493341 [GRCh38]
Chr12:100887119 [GRCh37]
Chr12:12q23.1
conflicting interpretations of pathogenicity|uncertain significance
NM_001206979.2(NR1H4):c.732+6A>G single nucleotide variant not specified [RCV000315552] Chr12:100535029 [GRCh38]
Chr12:100928807 [GRCh37]
Chr12:12q23.1
likely benign|uncertain significance
NM_001206979.2(NR1H4):c.438G>A (p.Gly146=) single nucleotide variant not provided [RCV000398943] Chr12:100511136 [GRCh38]
Chr12:100904914 [GRCh37]
Chr12:12q23.1
conflicting interpretations of pathogenicity|uncertain significance
NM_001206979.2(NR1H4):c.655C>T (p.His219Tyr) single nucleotide variant not provided [RCV000598009] Chr12:100534946 [GRCh38]
Chr12:100928724 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.831+1G>A single nucleotide variant not provided [RCV000597819] Chr12:100536611 [GRCh38]
Chr12:100930389 [GRCh37]
Chr12:12q23.1
likely pathogenic
NM_001206979.2(NR1H4):c.1072A>C (p.Asn358His) single nucleotide variant not provided [RCV000591860] Chr12:100540812 [GRCh38]
Chr12:100934590 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.1359G>T (p.Glu453Asp) single nucleotide variant not provided [RCV000592759] Chr12:100563417 [GRCh38]
Chr12:100957195 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.302C>T (p.Thr101Ile) single nucleotide variant not provided [RCV000598511] Chr12:100511000 [GRCh38]
Chr12:100904778 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.547C>T (p.Arg183Ter) single nucleotide variant not provided [RCV000592993] Chr12:100532559 [GRCh38]
Chr12:100926337 [GRCh37]
Chr12:12q23.1
pathogenic
NM_001206979.2(NR1H4):c.963T>C (p.Ile321=) single nucleotide variant not provided [RCV000593413] Chr12:100540703 [GRCh38]
Chr12:100934481 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.1A>G (p.Met1Val) single nucleotide variant not provided [RCV000730678] Chr12:100493324 [GRCh38]
Chr12:100887102 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.428C>T (p.Thr143Ile) single nucleotide variant not provided [RCV000731124] Chr12:100511126 [GRCh38]
Chr12:100904904 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.479T>C (p.Val160Ala) single nucleotide variant not provided [RCV000732994] Chr12:100532491 [GRCh38]
Chr12:100926269 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.1106T>C (p.Met369Thr) single nucleotide variant not provided [RCV000729567] Chr12:100561912 [GRCh38]
Chr12:100955690 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.588T>C (p.Cys196=) single nucleotide variant not provided [RCV000731264] Chr12:100532600 [GRCh38]
Chr12:100926378 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.1353C>T (p.His451=) single nucleotide variant not provided [RCV000732102] Chr12:100563411 [GRCh38]
Chr12:100957189 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.750C>T (p.Thr250=) single nucleotide variant not provided [RCV000733120] Chr12:100536529 [GRCh38]
Chr12:100930307 [GRCh37]
Chr12:12q23.1
conflicting interpretations of pathogenicity|uncertain significance
NM_001206979.2(NR1H4):c.933A>T (p.Gly311=) single nucleotide variant not provided [RCV000735151] Chr12:100540673 [GRCh38]
Chr12:100934451 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.445+5G>A single nucleotide variant not provided [RCV000728549] Chr12:100511148 [GRCh38]
Chr12:100904926 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.147C>T (p.Tyr49=) single nucleotide variant not provided [RCV000734101] Chr12:100510845 [GRCh38]
Chr12:100904623 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.141G>T (p.Ser47=) single nucleotide variant not provided [RCV000734154] Chr12:100510839 [GRCh38]
Chr12:100904617 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.923dup (p.Leu309fs) duplication not provided [RCV000734777] Chr12:100537033..100537034 [GRCh38]
Chr12:100930811..100930812 [GRCh37]
Chr12:12q23.1
likely pathogenic
NM_001206979.2(NR1H4):c.1319G>A (p.Arg440His) single nucleotide variant not provided [RCV000732869] Chr12:100563377 [GRCh38]
Chr12:100957155 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.268C>T (p.Arg90Cys) single nucleotide variant not provided [RCV000731778] Chr12:100510966 [GRCh38]
Chr12:100904744 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.740C>T (p.Thr247Ile) single nucleotide variant not provided [RCV000729173] Chr12:100536519 [GRCh38]
Chr12:100930297 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.1376G>A (p.Arg459Lys) single nucleotide variant not provided [RCV000734918] Chr12:100563434 [GRCh38]
Chr12:100957212 [GRCh37]
Chr12:12q23.1
uncertain significance
GRCh37/hg19 12q23.1-23.3(chr12:100580198-105804075)x3 copy number gain See cases [RCV000445929] Chr12:100580198..105804075 [GRCh37]
Chr12:12q23.1-23.3
uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12q23.1-23.2(chr12:100667424-101651880)x3 copy number gain See cases [RCV000510816] Chr12:100667424..101651880 [GRCh37]
Chr12:12q23.1-23.2
uncertain significance
NM_001206979.2(NR1H4):c.795C>T (p.Asn265=) single nucleotide variant not provided [RCV000594028] Chr12:100536574 [GRCh38]
Chr12:100930352 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.900G>A (p.Gln300=) single nucleotide variant not provided [RCV000596434] Chr12:100537016 [GRCh38]
Chr12:100930794 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.984G>A (p.Ala328=) single nucleotide variant not provided [RCV000597705] Chr12:100540724 [GRCh38]
Chr12:100934502 [GRCh37]
Chr12:12q23.1
uncertain significance
GRCh37/hg19 12q23.1(chr12:96719383-101537641)x3 copy number gain not provided [RCV000683473] Chr12:96719383..101537641 [GRCh37]
Chr12:12q23.1
likely pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12q22-23.2(chr12:94881995-103635998)x3 copy number gain not provided [RCV000750524] Chr12:94881995..103635998 [GRCh37]
Chr12:12q22-23.2
pathogenic
NM_001206979.2(NR1H4):c.1034del (p.Pro345fs) deletion Cholestasis, progressive familial intrahepatic, 5 [RCV000991448] Chr12:100540773 [GRCh38]
Chr12:100934551 [GRCh37]
Chr12:12q23.1
likely pathogenic
NM_001206979.2(NR1H4):c.82G>A (p.Val28Ile) single nucleotide variant not provided [RCV000883361] Chr12:100510780 [GRCh38]
Chr12:100904558 [GRCh37]
Chr12:12q23.1
benign
GRCh37/hg19 12q23.1(chr12:100880334-101045578)x3 copy number gain not provided [RCV000848903] Chr12:100880334..101045578 [GRCh37]
Chr12:12q23.1
uncertain significance
NM_001206979.2(NR1H4):c.831+8T>A single nucleotide variant not provided [RCV000959328] Chr12:100536618 [GRCh38]
Chr12:100930396 [GRCh37]
Chr12:12q23.1
benign
GRCh37/hg19 12q23.1(chr12:100815231-100990942)x1 copy number loss not provided [RCV001006524] Chr12:100815231..100990942 [GRCh37]
Chr12:12q23.1
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:7967 AgrOrtholog
COSMIC NR1H4 COSMIC
Ensembl Genes ENSG00000012504 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000188403 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000315442 UniProtKB/TrEMBL
  ENSP00000376712 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000446584 UniProtKB/TrEMBL
  ENSP00000446760 UniProtKB/TrEMBL
  ENSP00000446861 UniProtKB/TrEMBL
  ENSP00000447149 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000448506 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000448978 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000496824 UniProtKB/TrEMBL
  ENSP00000496908 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000188403 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000321046 UniProtKB/TrEMBL
  ENST00000392986 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000546380 UniProtKB/TrEMBL
  ENST00000548621 UniProtKB/TrEMBL
  ENST00000548884 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000549996 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000551184 UniProtKB/TrEMBL
  ENST00000551379 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000648861 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000649582 UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000012504 GTEx
HGNC ID HGNC:7967 ENTREZGENE
Human Proteome Map NR1H4 Human Proteome Map
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NR_LBD_NR1H4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ThyrH_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:9971 UniProtKB/Swiss-Prot
NCBI Gene 9971 ENTREZGENE
OMIM 603826 OMIM
  617049 OMIM
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA31752 PharmGKB
PRINTS STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THYROIDHORMR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B6ZGS9 ENTREZGENE, UniProtKB/TrEMBL
  F1DAL1 ENTREZGENE, UniProtKB/TrEMBL
  F8W1M1_HUMAN UniProtKB/TrEMBL
  F8W656_HUMAN UniProtKB/TrEMBL
  G8JLB0_HUMAN UniProtKB/TrEMBL
  H0YHD5_HUMAN UniProtKB/TrEMBL
  NR1H4_HUMAN UniProtKB/Swiss-Prot
  Q6IPQ7_HUMAN UniProtKB/TrEMBL
  Q96RI1 ENTREZGENE
UniProt Secondary A1L4K5 UniProtKB/Swiss-Prot
  B7Z412 UniProtKB/Swiss-Prot
  B7ZM06 UniProtKB/Swiss-Prot
  F8VYG8 UniProtKB/Swiss-Prot
  Q8NFP5 UniProtKB/Swiss-Prot
  Q8NFP6 UniProtKB/Swiss-Prot
  Q92943 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 NR1H4  nuclear receptor subfamily 1 group H member 4  NR1H4  nuclear receptor subfamily 1, group H, member 4  Symbol and/or name change 5135510 APPROVED