TRIM31 (tripartite motif containing 31) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TRIM31 (tripartite motif containing 31) Homo sapiens
Analyze
Symbol: TRIM31
Name: tripartite motif containing 31
RGD ID: 1318479
HGNC Page HGNC
Description: Enables transcription coactivator activity. Involved in several processes, including negative regulation of viral entry into host cell; negative regulation of viral transcription; and positive regulation of DNA-binding transcription factor activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C6orf13; E3 ubiquitin-protein ligase TRIM31; HCG1; HCGI; ring finger protein; RING-type E3 ubiquitin transferase TRIM31; RNF; tripartite motif-containing 31; tripartite motif-containing 31 gamma; tripartite motif-containing protein 31
RGD Orthologs
Mouse
Rat
Bonobo
Squirrel
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl630,102,897 - 30,113,090 (-)EnsemblGRCh38hg38GRCh38
GRCh38630,102,892 - 30,113,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37630,070,674 - 30,080,867 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,178,653 - 30,188,846 (-)NCBINCBI36hg18NCBI36
Build 34630,178,654 - 30,188,833NCBI
Celera631,668,926 - 31,679,124 (-)NCBI
Cytogenetic Map6p22.1NCBI
HuRef629,868,836 - 29,879,034 (-)NCBIHuRef
CHM1_1630,072,756 - 30,082,946 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytosol  (TAS)
mitochondrion  (IEA)

Molecular Function

References

Additional References at PubMed
PMID:8125298   PMID:8490624   PMID:11331580   PMID:12477932   PMID:14574404   PMID:14759258   PMID:15489334   PMID:16189514   PMID:16341674   PMID:16344560   PMID:16702430   PMID:16712791  
PMID:18248090   PMID:18773414   PMID:19549727   PMID:19851445   PMID:20125193   PMID:20211142   PMID:21143188   PMID:21231912   PMID:21302343   PMID:21873635   PMID:22493164   PMID:23077300  
PMID:23105109   PMID:23417110   PMID:24489884   PMID:24566900   PMID:25217961   PMID:25416956   PMID:25590999   PMID:27216961   PMID:27743201   PMID:27929086   PMID:27992402   PMID:28967907  
PMID:29449217   PMID:29643511   PMID:29665353   PMID:29864908   PMID:29930725   PMID:31129970   PMID:31304625   PMID:32020206   PMID:32232394   PMID:32296183   PMID:32323100   PMID:32511263  
PMID:32716108   PMID:32814053   PMID:33311639   PMID:34105476  


Genomics

Comparative Map Data
TRIM31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl630,102,897 - 30,113,090 (-)EnsemblGRCh38hg38GRCh38
GRCh38630,102,892 - 30,113,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37630,070,674 - 30,080,867 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,178,653 - 30,188,846 (-)NCBINCBI36hg18NCBI36
Build 34630,178,654 - 30,188,833NCBI
Celera631,668,926 - 31,679,124 (-)NCBI
Cytogenetic Map6p22.1NCBI
HuRef629,868,836 - 29,879,034 (-)NCBIHuRef
CHM1_1630,072,756 - 30,082,946 (-)NCBICHM1_1
Trim31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,209,022 - 37,221,109 (+)NCBIGRCm39mm39
GRCm39 Ensembl1737,209,010 - 37,221,106 (+)Ensembl
GRCm381736,898,130 - 36,910,217 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,898,118 - 36,910,214 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,035,075 - 37,047,162 (+)NCBIGRCm37mm9NCBIm37
MGSCv361736,506,183 - 36,518,270 (+)NCBImm8
Celera1740,317,255 - 40,329,416 (+)NCBICelera
Cytogenetic Map17B1NCBI
Trim31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2201,653,165 - 1,666,494 (-)NCBI
Rnor_6.0 Ensembl202,146,257 - 2,159,631 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0202,146,245 - 2,159,875 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0204,183,577 - 4,196,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,745,437 - 1,758,194 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1201,746,131 - 1,757,962 (-)NCBI
Celera202,361,720 - 2,375,040 (-)NCBICelera
Cytogenetic Map20p12NCBI
TRIM31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1630,550,802 - 30,560,993 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,550,802 - 30,560,977 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0629,880,668 - 29,890,905 (-)NCBIMhudiblu_PPA_v0panPan3
Trim31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,646,388 - 32,657,283 (-)NCBI
SpeTri2.0NW_004936723934,808 - 945,279 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1722,665,150 - 22,681,616 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,946,635 - 24,960,048 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
D6S2967  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371820,288,703 - 20,289,022UniSTSGRCh37
GRCh37630,074,773 - 30,074,968UniSTSGRCh37
Build 36630,182,752 - 30,182,947RGDNCBI36
Celera1817,102,873 - 17,103,192UniSTS
Celera631,673,025 - 31,673,220RGD
Cytogenetic Map6p21.3UniSTS
HuRef1817,143,216 - 17,143,535UniSTS
HuRef629,872,935 - 29,873,130UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2014
Count of miRNA genes:835
Interacting mature miRNAs:1005
Transcripts:ENST00000376734, ENST00000468264, ENST00000471695, ENST00000480808, ENST00000484583, ENST00000485864, ENST00000493404, ENST00000540829
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 516 1 45 45 99 47 1 1 28 180 22
Low 542 2 340 226 187 223 839 16 32 47 561 359 11 8 374
Below cutoff 903 1683 1221 319 990 165 2260 1048 2009 248 585 1093 157 950 1394 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_007028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_134870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_134871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB088088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB103594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB202083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB303153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF230386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF230387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK222729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL669914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL671859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC017017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG403536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM847963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX005441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX088647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX322644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX897730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB142265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB147821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR753815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR925727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT009552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB244000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X81006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y07828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000376734   ⟹   ENSP00000365924
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,102,897 - 30,113,090 (-)Ensembl
RefSeq Acc Id: ENST00000468264
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,103,873 - 30,108,199 (-)Ensembl
RefSeq Acc Id: ENST00000471695
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,102,897 - 30,105,657 (-)Ensembl
RefSeq Acc Id: ENST00000480808
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,108,746 - 30,111,706 (-)Ensembl
RefSeq Acc Id: ENST00000484583
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,103,931 - 30,105,440 (-)Ensembl
RefSeq Acc Id: ENST00000485864
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,105,196 - 30,112,186 (-)Ensembl
RefSeq Acc Id: ENST00000493404
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,111,218 - 30,112,475 (-)Ensembl
RefSeq Acc Id: NM_007028   ⟹   NP_008959
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,102,897 - 30,113,090 (-)NCBI
GRCh37630,070,674 - 30,080,867 (-)RGD
Build 36630,178,653 - 30,188,846 (-)NCBI Archive
Celera631,668,926 - 31,679,124 (-)RGD
HuRef629,868,836 - 29,879,034 (-)RGD
CHM1_1630,072,756 - 30,082,962 (-)NCBI
Sequence:
RefSeq Acc Id: NR_134870
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,102,897 - 30,113,090 (-)NCBI
CHM1_1630,072,756 - 30,082,962 (-)NCBI
Sequence:
RefSeq Acc Id: NR_134871
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,102,897 - 30,113,090 (-)NCBI
CHM1_1630,072,756 - 30,082,962 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011514264   ⟹   XP_011512566
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,102,892 - 30,113,090 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011514265   ⟹   XP_011512567
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,102,892 - 30,113,090 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011514266   ⟹   XP_011512568
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,108,075 - 30,113,090 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_008959 (Get FASTA)   NCBI Sequence Viewer  
  XP_011512566 (Get FASTA)   NCBI Sequence Viewer  
  XP_011512567 (Get FASTA)   NCBI Sequence Viewer  
  XP_011512568 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG50165 (Get FASTA)   NCBI Sequence Viewer  
  AAG50166 (Get FASTA)   NCBI Sequence Viewer  
  AAH16866 (Get FASTA)   NCBI Sequence Viewer  
  AAH17017 (Get FASTA)   NCBI Sequence Viewer  
  AAP35321 (Get FASTA)   NCBI Sequence Viewer  
  AQY77172 (Get FASTA)   NCBI Sequence Viewer  
  AQY77173 (Get FASTA)   NCBI Sequence Viewer  
  AQY77174 (Get FASTA)   NCBI Sequence Viewer  
  AQY77175 (Get FASTA)   NCBI Sequence Viewer  
  AQY77176 (Get FASTA)   NCBI Sequence Viewer  
  AQY77177 (Get FASTA)   NCBI Sequence Viewer  
  AQY77178 (Get FASTA)   NCBI Sequence Viewer  
  AQY77179 (Get FASTA)   NCBI Sequence Viewer  
  AQY77180 (Get FASTA)   NCBI Sequence Viewer  
  AQY77181 (Get FASTA)   NCBI Sequence Viewer  
  AQY77182 (Get FASTA)   NCBI Sequence Viewer  
  AQY77183 (Get FASTA)   NCBI Sequence Viewer  
  AQY77184 (Get FASTA)   NCBI Sequence Viewer  
  AQY77185 (Get FASTA)   NCBI Sequence Viewer  
  BAD96449 (Get FASTA)   NCBI Sequence Viewer  
  BAE78603 (Get FASTA)   NCBI Sequence Viewer  
  BAF82959 (Get FASTA)   NCBI Sequence Viewer  
  BAH58735 (Get FASTA)   NCBI Sequence Viewer  
  CAA69165 (Get FASTA)   NCBI Sequence Viewer  
  CAM26290 (Get FASTA)   NCBI Sequence Viewer  
  EAX03257 (Get FASTA)   NCBI Sequence Viewer  
  EAX03258 (Get FASTA)   NCBI Sequence Viewer  
  EAX03259 (Get FASTA)   NCBI Sequence Viewer  
  EAX03260 (Get FASTA)   NCBI Sequence Viewer  
  EAX03261 (Get FASTA)   NCBI Sequence Viewer  
  EAX03262 (Get FASTA)   NCBI Sequence Viewer  
  EAX03263 (Get FASTA)   NCBI Sequence Viewer  
  Q9BZY9 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_008959   ⟸   NM_007028
- UniProtKB: Q9BZY9 (UniProtKB/Swiss-Prot),   Q2L6J1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011512566   ⟸   XM_011514264
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011512567   ⟸   XM_011514265
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011512568   ⟸   XM_011514266
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSP00000365924   ⟸   ENST00000376734
Protein Domains
B box-type   RING-type


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p22.3-21.33(chr6:18120520-30767516)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|See cases [RCV000052180] Chr6:18120520..30767516 [GRCh38]
Chr6:18120751..30735293 [GRCh37]
Chr6:18228730..30843272 [NCBI36]
Chr6:6p22.3-21.33
pathogenic
NM_007028.3(TRIM31):c.767+310T>C single nucleotide variant Lung cancer [RCV000096815] Chr6:30108716 [GRCh38]
Chr6:30076493 [GRCh37]
Chr6:6p22.1
uncertain significance
GRCh38/hg38 6p25.2-21.33(chr6:3224310-30657190)x3 copy number gain See cases [RCV000138956] Chr6:3224310..30657190 [GRCh38]
Chr6:3224544..30624967 [GRCh37]
Chr6:3169543..30732946 [NCBI36]
Chr6:6p25.2-21.33
pathogenic
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3
pathogenic
chr6:29910378..30075843 complex variant complex Ductal breast carcinoma [RCV000207211] Chr6:29910378..30075843 [GRCh37]
Chr6:6p22.1
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.1-21.32(chr6:28130359-32108367)x3 copy number gain not provided [RCV000745592] Chr6:28130359..32108367 [GRCh37]
Chr6:6p22.1-21.32
uncertain significance
NM_007028.5(TRIM31):c.1044G>A (p.Gly348=) single nucleotide variant not provided [RCV000970979] Chr6:30103770 [GRCh38]
Chr6:30071547 [GRCh37]
Chr6:6p22.1
benign
NM_007028.5(TRIM31):c.525A>C (p.Glu175Asp) single nucleotide variant not provided [RCV000964267] Chr6:30110667 [GRCh38]
Chr6:30078444 [GRCh37]
Chr6:6p22.1
likely benign
NM_007028.5(TRIM31):c.707A>G (p.Lys236Arg) single nucleotide variant not provided [RCV000884600] Chr6:30110485 [GRCh38]
Chr6:30078262 [GRCh37]
Chr6:6p22.1
likely benign
NM_007028.5(TRIM31):c.559C>T (p.Leu187Phe) single nucleotide variant not provided [RCV000964266] Chr6:30110633 [GRCh38]
Chr6:30078410 [GRCh37]
Chr6:6p22.1
likely benign
NM_007028.5(TRIM31):c.734A>G (p.Gln245Arg) single nucleotide variant not provided [RCV000946925] Chr6:30110458 [GRCh38]
Chr6:30078235 [GRCh37]
Chr6:6p22.1
benign
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1
pathogenic
NM_007028.5(TRIM31):c.18T>G (p.Phe6Leu) single nucleotide variant not provided [RCV000963327] Chr6:30112788 [GRCh38]
Chr6:30080565 [GRCh37]
Chr6:6p22.1
benign
NM_007028.5(TRIM31):c.15G>T (p.Gln5His) single nucleotide variant not provided [RCV000964268] Chr6:30112791 [GRCh38]
Chr6:30080568 [GRCh37]
Chr6:6p22.1
likely benign
NM_007028.5(TRIM31):c.1228G>T (p.Glu410Ter) single nucleotide variant not provided [RCV000881999] Chr6:30103586 [GRCh38]
Chr6:30071363 [GRCh37]
Chr6:6p22.1
likely benign
NM_007028.5(TRIM31):c.379A>G (p.Asn127Asp) single nucleotide variant not provided [RCV000956373] Chr6:30112427 [GRCh38]
Chr6:30080204 [GRCh37]
Chr6:6p22.1
benign
NM_007028.5(TRIM31):c.303G>A (p.Met101Ile) single nucleotide variant not provided [RCV000956374] Chr6:30112503 [GRCh38]
Chr6:30080280 [GRCh37]
Chr6:6p22.1
benign
NM_007028.5(TRIM31):c.214C>T (p.Arg72Trp) single nucleotide variant not provided [RCV000956375] Chr6:30112592 [GRCh38]
Chr6:30080369 [GRCh37]
Chr6:6p22.1
benign
NM_007028.5(TRIM31):c.704T>C (p.Leu235Pro) single nucleotide variant not provided [RCV000956372] Chr6:30110488 [GRCh38]
Chr6:30078265 [GRCh37]
Chr6:6p22.1
benign
NM_007028.5(TRIM31):c.50C>G (p.Pro17Arg) single nucleotide variant not provided [RCV000956376] Chr6:30112756 [GRCh38]
Chr6:30080533 [GRCh37]
Chr6:6p22.1
benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:16289 AgrOrtholog
COSMIC TRIM31 COSMIC
Ensembl Genes ENSG00000137397 UniProtKB/Swiss-Prot
  ENSG00000204616 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000223531 UniProtKB/Swiss-Prot
  ENSG00000224168 UniProtKB/Swiss-Prot
  ENSG00000224542 UniProtKB/TrEMBL
  ENSG00000225130 UniProtKB/Swiss-Prot
  ENSG00000226402 UniProtKB/TrEMBL
  ENSG00000233573 UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000350182 UniProtKB/Swiss-Prot
  ENSP00000365924 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000390551 UniProtKB/Swiss-Prot
  ENSP00000391685 UniProtKB/Swiss-Prot
  ENSP00000398677 UniProtKB/Swiss-Prot
  ENSP00000404933 UniProtKB/TrEMBL
  ENSP00000409501 UniProtKB/Swiss-Prot
  ENSP00000411879 UniProtKB/TrEMBL
Ensembl Transcript ENST00000357569 UniProtKB/Swiss-Prot
  ENST00000376734 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000422484 UniProtKB/TrEMBL
  ENST00000433864 UniProtKB/Swiss-Prot
  ENST00000445679 UniProtKB/Swiss-Prot
  ENST00000449412 UniProtKB/Swiss-Prot
  ENST00000453266 UniProtKB/Swiss-Prot
  ENST00000455349 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000137397 GTEx
  ENSG00000204616 GTEx
  ENSG00000223531 GTEx
  ENSG00000224168 GTEx
  ENSG00000224542 GTEx
  ENSG00000225130 GTEx
  ENSG00000226402 GTEx
  ENSG00000233573 GTEx
HGNC ID HGNC:16289 ENTREZGENE
Human Proteome Map TRIM31 Human Proteome Map
InterPro Znf_B-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_B-box_chordata UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:11074 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 11074 ENTREZGENE
OMIM 609316 OMIM
Pfam zf-B_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA38117 PharmGKB
PRINTS BBOXZNFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ZF_BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JJX2_HUMAN UniProtKB/TrEMBL
  A0A140T9J6_HUMAN UniProtKB/TrEMBL
  C4B4E3_HUMAN UniProtKB/TrEMBL
  Q2L6J1 ENTREZGENE, UniProtKB/TrEMBL
  Q9BZY9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A1U9X8Q7 UniProtKB/TrEMBL
  A6NLX6 UniProtKB/Swiss-Prot
  A9R9Q4 UniProtKB/Swiss-Prot
  Q53H52 UniProtKB/Swiss-Prot
  Q5RI37 UniProtKB/Swiss-Prot
  Q5SRJ7 UniProtKB/Swiss-Prot
  Q5SRJ8 UniProtKB/Swiss-Prot
  Q5SS28 UniProtKB/Swiss-Prot
  Q96AK4 UniProtKB/Swiss-Prot
  Q96AP8 UniProtKB/Swiss-Prot
  Q99579 UniProtKB/Swiss-Prot
  Q9BZY8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-09-01 TRIM31  tripartite motif containing 31  TRIM31  tripartite motif containing 31  Symbol and/or name change 5135510 APPROVED
2011-07-27 TRIM31  tripartite motif containing 31  TRIM31  tripartite motif-containing 31  Symbol and/or name change 5135510 APPROVED