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Gene: RNF34 (ring finger protein 34) Homo sapiens
Symbol: RNF34
Name: ring finger protein 34
RGD ID: 1352323
Description: Exhibits several functions, including p53 binding activity; ubiquitin protein ligase activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular protein metabolic process; negative regulation of apoptotic process; and negative regulation of signal transduction by p53 class mediator. Localizes to cytoplasm; nuclear body; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CARP-1; CARP1; caspase regulator CARP1; caspases-8 and -10-associated RING finger protein 1; E3 ubiquitin-protein ligase RNF34; FLJ21786; FYVE-RING finger protein MOMO; hRFI; human RING finger homologous to inhibitor of apoptosis protein; RFI; RIF; RIFF; ring finger protein 34, E3 ubiquitin protein ligase; RING finger protein RIFF; RING-type E3 ubiquitin transferase RNF34
Mus musculus (house mouse) : Rnf34 (ring finger protein 34)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rnf34 (ring finger protein 34)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf34 (ring finger protein 34)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF34 (ring finger protein 34)
Canis lupus familiaris (dog) : RNF34 (ring finger protein 34)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf34 (ring finger protein 34)
Sus scrofa (pig) : RNF34 (ring finger protein 34)
Chlorocebus sabaeus (African green monkey) : RNF34 (ring finger protein 34)
Heterocephalus glaber (naked mole-rat) : Rnf34 (ring finger protein 34)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl12121,400,041 - 121,430,623 (+)EnsemblGRCh38hg38GRCh38
GRCh3812121,400,096 - 121,424,352 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712121,837,886 - 121,862,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612120,322,285 - 120,346,538 (+)NCBINCBI36hg18NCBI36
Build 3412120,300,621 - 120,324,875NCBI
Celera12121,475,573 - 121,499,826 (+)NCBI
Cytogenetic Map12q24.31NCBI
HuRef12118,847,675 - 118,871,945 (+)NCBIHuRef
CHM1_112121,806,339 - 121,830,742 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RNF34
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352323
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.