Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RNF185 (ring finger protein 185) Homo sapiens
Symbol: RNF185
Name: ring finger protein 185
Description: Exhibits ubiquitin binding activity; ubiquitin protein ligase activity; and ubiquitin-like protein conjugating enzyme binding activity. Involved in positive regulation of ERAD pathway; protein autoubiquitination; and ubiquitin-dependent ERAD pathway. Localizes to endoplasmic reticulum; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BSK65-MONO1; BSK65-MONO2; BSK65-PANC1; BSK65-PANC2; BSK65-TEST1; BSK65-TEST2; BSK65-TEST3; E3 ubiquitin-protein ligase RNF185; FLJ38628; RING-type E3 ubiquitin transferase RNF185
Mus musculus (house mouse) : Rnf185 (ring finger protein 185)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rnf185 (ring finger protein 185)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf185 (ring finger protein 185)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF185 (ring finger protein 185)
Canis lupus familiaris (dog) : RNF185 (ring finger protein 185)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf185 (ring finger protein 185)
Sus scrofa (pig) : RNF185 (ring finger protein 185)
Chlorocebus sabaeus (African green monkey) : RNF185 (ring finger protein 185)
Heterocephalus glaber (naked mole-rat) : Rnf185 (ring finger protein 185)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2231,160,182 - 31,207,019 (+)EnsemblGRCh38hg38GRCh38
GRCh382231,160,182 - 31,207,019 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372231,556,138 - 31,603,005 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,886,179 - 29,933,000 (+)NCBINCBI36hg18NCBI36
Celera2215,356,214 - 15,403,106 (+)NCBI
Cytogenetic Map22q12.2NCBI
HuRef2214,517,777 - 14,564,817 (+)NCBIHuRef
CHM1_12231,515,988 - 31,562,845 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on RNF185
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1602840
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.