1,3-dinitrobenzene - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	1,3-dinitrobenzene	go back to main search page
Accession:	CHEBI:51397	browse the term
Definition:	A dinitrobenzene that is benzene disubstituted at positions 1 and 3 with nitro groups.
Synonyms:	related_synonym:	1,3-Dinitrobenzol; 2,4-Dinitrobenzene; DINITROPHENYLENE; Formula=C6H4N2O4; InChI=1S/C6H4N2O4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H; InChIKey=WDCYWAQPCXBPJA-UHFFFAOYSA-N; SMILES=[O-][N+](=O)c1cccc(c1)[N+]([O-])=O; m-DNB; m-Dinitrobenzene; meta-Dinitrobenzene
	alt_id:	CHEBI:44536
	xref:	Beilstein:1105654; CAS:99-65-0
	xref_mesh:	MESH:C017906
	xref:	MetaCyc:13-DINITROBENZENE; PDBeChem:NIN; PMID:12119003; PMID:7744316; PMID:9291486; PPDB:1637; Reaxys:1105654

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Genes (391)

1,3-dinitrobenzene

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 0610010K14 gene

increases expression

3-dinitrobenzene results in increased expression of C10H17ORF49 mRNA

NCBI chr11:70,126,030...70,128,808
Ensembl chr11:70,126,032...70,128,740

G

RIKEN cDNA 3110040N11 gene

decreases expression

3-dinitrobenzene results in decreased expression of C1H15ORF40 mRNA

NCBI chr 7:81,430,031...81,439,203
Ensembl chr 7:81,431,930...81,439,226

G

RIKEN cDNA 4930579G24 gene

decreases expression

3-dinitrobenzene results in decreased expression of C2H4ORF46 mRNA

NCBI chr 3:79,536,386...79,540,127
Ensembl chr 3:79,536,386...79,540,127

G

4-aminobutyrate aminotransferase

increases oxidation

3-dinitrobenzene results in increased oxidation of ABAT protein

NCBI chr16:8,331,293...8,439,432
Ensembl chr16:8,331,293...8,439,432

G

ATP-binding cassette, sub-family A member 5

decreases expression

3-dinitrobenzene results in decreased expression of ABCA5 mRNA

NCBI chr11:110,160,195...110,228,542
Ensembl chr11:110,160,195...110,228,542

G

ATP-binding cassette, sub-family B member 1A

increases expression
decreases expression

3-dinitrobenzene results in increased expression of ABCB1A mRNA
3-dinitrobenzene results in decreased expression of ABCB1 mRNA

PMID:16142770 PMID:21983209

NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575

G

abhydrolase domain containing 10

increases expression

3-dinitrobenzene results in increased expression of ABHD10 protein

NCBI chr16:45,550,088...45,563,355
Ensembl chr16:45,550,088...45,563,318

G

acetyl-CoA acyltransferase 2

increases expression

3-dinitrobenzene results in increased expression of ACAA2 protein

NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279

G

acetyl-Coenzyme A acetyltransferase 1

increases oxidation

3-dinitrobenzene results in increased oxidation of ACAT1 protein

NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682

G

aconitase 2, mitochondrial

increases metabolic processing

3-dinitrobenzene results in increased metabolism of ACO2 protein

NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334

G

acyl-CoA thioesterase 2

increases expression

3-dinitrobenzene results in increased expression of ACOT2 mRNA

PMID:21983209 PMID:24140754

NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647

G

ajuba LIM protein

increases expression

3-dinitrobenzene results in increased expression of AJUBA mRNA

NCBI chr14:54,804,926...54,815,118
Ensembl chr14:54,804,929...54,815,015

G

albumin

increases metabolic processing

3-dinitrobenzene results in increased metabolism of ALB protein

NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461

G

aldehyde dehydrogenase 2, mitochondrial

affects binding
increases metabolic processing

3-dinitrobenzene binds to ALDH2 protein
3-dinitrobenzene results in increased metabolism of ALDH2 protein

PMID:11896682 PMID:21402099

NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887

G

alkB homolog 6

increases expression

3-dinitrobenzene results in increased expression of ALKBH6 mRNA

NCBI chr 7:30,008,178...30,013,728
Ensembl chr 7:30,008,142...30,013,729

G

alkaline phosphatase, liver/bone/kidney

affects expression

3-dinitrobenzene affects the expression of ALPL mRNA

NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695

G

ankyrin repeat domain 2

decreases expression

3-dinitrobenzene results in decreased expression of ANKRD2 protein

NCBI chr19:42,024,358...42,033,550
Ensembl chr19:42,024,439...42,033,549

G

ankyrin repeat domain 34B

decreases expression

3-dinitrobenzene results in decreased expression of ANKRD34B mRNA

NCBI chr13:92,562,413...92,578,166
Ensembl chr13:92,562,404...92,578,166

G

annexin A2

increases expression

3-dinitrobenzene results in increased expression of ANXA2 mRNA

NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077

G

apoptotic peptidase activating factor 1

increases expression

3-dinitrobenzene results in increased expression of APAF1 mRNA

NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632

G

aquaporin 4

decreases expression

3-dinitrobenzene results in decreased expression of AQP4 mRNA

NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3

increases expression

3-dinitrobenzene results in increased expression of ARAP3 mRNA

NCBI chr18:38,105,676...38,132,583
Ensembl chr18:38,105,681...38,132,022

G

Rho GTPase activating protein 44

decreases expression

3-dinitrobenzene results in decreased expression of ARHGAP44 mRNA

NCBI chr11:64,892,865...65,053,779
Ensembl chr11:64,892,865...65,053,787

G

armadillo repeat containing, X-linked 6

increases expression

3-dinitrobenzene results in increased expression of ARMCX6 mRNA

NCBI chr X:133,649,204...133,657,236
Ensembl chr X:133,649,210...133,652,166

G

actin related protein 2/3 complex, subunit 4

decreases expression

3-dinitrobenzene results in decreased expression of ARPC4 protein

NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409

G

ankyrin repeat and SOCs box-containing 5

decreases expression

3-dinitrobenzene results in decreased expression of ASB5 mRNA

NCBI chr 8:55,003,366...55,040,877
Ensembl chr 8:54,982,615...55,040,910

G

autophagy related 4C, cysteine peptidase

decreases expression

3-dinitrobenzene results in decreased expression of ATG4C mRNA

NCBI chr 4:99,077,181...99,185,495
Ensembl chr 4:99,082,171...99,148,024

G

ATPase, Ca++ transporting, plasma membrane 2

increases oxidation

3-dinitrobenzene results in increased oxidation of ATP2B2 protein

NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574

G

ATP synthase F1 subunit beta

increases metabolic processing

3-dinitrobenzene results in increased metabolism of ATP5F1B protein

NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260

G

ATPase, H+ transporting, lysosomal V0 subunit A1

increases expression

3-dinitrobenzene results in increased expression of ATP6V0A1 mRNA

NCBI chr11:100,899,262...100,954,545
Ensembl chr11:100,900,278...100,954,545

G

ATPase, H+ transporting, lysosomal V1 subunit C2

decreases expression

3-dinitrobenzene results in decreased expression of ATP6V1C2 mRNA

NCBI chr12:17,334,722...17,375,700
Ensembl chr12:17,334,722...17,379,360

G

aurora kinase C

decreases expression

3-dinitrobenzene results in decreased expression of AURKC mRNA

NCBI chr 7:6,998,346...7,006,090
Ensembl chr 7:6,998,299...7,006,090

G

advillin

decreases expression

3-dinitrobenzene results in decreased expression of AVIL mRNA

NCBI chr10:126,835,933...126,856,857
Ensembl chr10:126,836,578...126,856,863

G

beta-2 microglobulin

increases expression

3-dinitrobenzene results in increased expression of B2M mRNA

NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564

G

UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1

decreases expression

3-dinitrobenzene results in decreased expression of B3GALNT1 mRNA

NCBI chr 3:69,481,252...69,506,305
Ensembl chr 3:69,481,491...69,506,293

G

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5

decreases expression

3-dinitrobenzene results in decreased expression of B3GALT5 mRNA

NCBI chr16:96,037,001...96,121,059
Ensembl chr16:96,037,001...96,121,059

G

BCL2-antagonist/killer 1

increases expression

3-dinitrobenzene results in increased expression of BAK1 mRNA

NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983

G

BCL2-associated X protein

increases expression

3-dinitrobenzene results in increased expression of BAX mRNA
3-dinitrobenzene results in increased expression of BAX mRNA; 3-dinitrobenzene results in increased expression of BAX protein

PMID:16025311 PMID:19477251

NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322

G

BCL2 binding component 3

increases expression

3-dinitrobenzene results in increased expression of BBC3 mRNA

PMID:22841810 PMID:24140754

NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130

G

BCL11 transcription factor A

decreases expression

3-dinitrobenzene results in decreased expression of BCL11A mRNA

NCBI chr11:24,026,498...24,123,558
Ensembl chr11:24,028,056...24,124,123

G

B cell leukemia/lymphoma 2

increases expression
decreases expression

3-dinitrobenzene results in increased expression of BCL2 mRNA
3-dinitrobenzene results in decreased expression of BCL2 mRNA; 3-dinitrobenzene results in decreased expression of BCL2 protein

PMID:16025311 PMID:19477251

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

BCL2-like 1

affects response to substance
increases expression
decreases response to substance
decreases expression

BCL2L1 protein affects the susceptibility to 3-dinitrobenzene
3-dinitrobenzene results in increased expression of BCL2L1 mRNA
BCL2L1 protein results in decreased susceptibility to 3-dinitrobenzene
3-dinitrobenzene results in decreased expression of BCL2L1 mRNA

PMID:10960601 PMID:16025311 PMID:16257055 PMID:22841810

NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648

G

B cell CLL/lymphoma 9

increases expression

3-dinitrobenzene results in increased expression of BCL9 mRNA

NCBI chr 3:97,110,974...97,205,718
Ensembl chr 3:97,110,978...97,205,233

G

basic helix-loop-helix family, member e40

increases expression

3-dinitrobenzene results in increased expression of BHLHE40 mRNA

NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886

G

basic helix-loop-helix family, member e41

decreases expression

3-dinitrobenzene results in decreased expression of BHLHE41 mRNA

NCBI chr 6:145,803,969...145,811,146
Ensembl chr 6:145,803,969...145,811,284

G

baculoviral IAP repeat-containing 2

decreases expression

3-dinitrobenzene results in decreased expression of BIRC2 mRNA

PMID:22841810 PMID:24140754

NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065

G

BMP-binding endothelial regulator

decreases expression

3-dinitrobenzene results in decreased expression of BMPER mRNA

NCBI chr 9:23,134,372...23,396,511
Ensembl chr 9:23,134,372...23,396,496

G

bone morphogenic protein/retinoic acid inducible neural-specific 2

decreases expression

3-dinitrobenzene results in decreased expression of BRINP2 mRNA

NCBI chr 1:158,072,835...158,185,096
Ensembl chr 1:158,072,839...158,183,896

G

complement component 1, q subcomponent, alpha polypeptide

increases expression

3-dinitrobenzene results in increased expression of C1QA mRNA

NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114

G

complement component 1, q subcomponent, beta polypeptide

increases expression

3-dinitrobenzene results in increased expression of C1QB mRNA

NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498

G

complement C2

decreases expression

3-dinitrobenzene results in decreased expression of C2 protein

NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241

G

C2 calcium-dependent domain containing 4B

decreases expression

3-dinitrobenzene results in decreased expression of C2CD4B mRNA

NCBI chr 9:67,623,506...67,668,215
Ensembl chr 9:67,666,719...67,668,212

G

complement component 3a receptor 1

increases expression

3-dinitrobenzene results in increased expression of C3AR1 mRNA

NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120

G

calcium binding protein 4

decreases expression

3-dinitrobenzene results in decreased expression of CABP4 mRNA

NCBI chr19:4,185,422...4,189,608
Ensembl chr19:4,185,422...4,194,032

G

calcium channel, voltage-dependent, T type, alpha 1H subunit

decreases expression

3-dinitrobenzene results in decreased expression of CACNA1H mRNA

NCBI chr17:25,593,259...25,655,308
Ensembl chr17:25,593,259...25,652,759

G

calmodulin-like 3

increases expression

3-dinitrobenzene results in increased expression of CALML3 mRNA

NCBI chr13:3,852,893...3,854,318
Ensembl chr13:3,852,896...3,854,316

G

calreticulin

increases metabolic processing

3-dinitrobenzene results in increased metabolism of CALR protein

NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563

G

calumenin

increases expression

3-dinitrobenzene results in increased expression of CALU mRNA

NCBI chr 6:29,348,105...29,376,674
Ensembl chr 6:29,348,068...29,377,109

G

caspase 3

increases cleavage

3-dinitrobenzene results in increased cleavage of CASP3 protein

PMID:19477251 PMID:22841810

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caspase 6

increases cleavage
increases expression

3-dinitrobenzene results in increased cleavage of CASP6 protein
3-dinitrobenzene results in increased expression of CASP6 mRNA

NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752

G

cell division cycle and apoptosis regulator 1

decreases expression

3-dinitrobenzene results in decreased expression of CCAR1 mRNA

NCBI chr10:62,579,707...62,628,147
Ensembl chr10:62,579,707...62,628,065

G

coiled-coil domain containing 107

increases expression

3-dinitrobenzene results in increased expression of CCDC107 mRNA

NCBI chr 4:43,493,365...43,495,921
Ensembl chr 4:43,492,900...43,495,921

G

coiled-coil domain containing 117

decreases expression

3-dinitrobenzene results in decreased expression of CCDC117 mRNA

NCBI chr11:5,478,887...5,492,217
Ensembl chr11:5,478,887...5,492,187

G

coiled coil domain containing 88A

decreases expression

3-dinitrobenzene results in decreased expression of CCDC88A mRNA

NCBI chr11:29,323,521...29,460,808
Ensembl chr11:29,323,658...29,460,808

G

coiled-coil domain containing 97

decreases expression

3-dinitrobenzene results in decreased expression of CCDC97 mRNA

NCBI chr 7:25,410,537...25,418,460
Ensembl chr 7:25,410,531...25,418,513

G

cellular communication network factor 2

increases expression

3-dinitrobenzene results in increased expression of CCN2 mRNA

NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581

G

C-C motif chemokine receptor-like 2

increases expression

3-dinitrobenzene results in increased expression of CCRL2 mRNA

NCBI chr 9:110,883,902...110,886,586
Ensembl chr 9:110,883,554...110,886,587

G

CD55 molecule, decay accelerating factor for complement

decreases expression

3-dinitrobenzene results in decreased expression of CD55 mRNA

NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481

G

CDC16 cell division cycle 16

decreases expression

3-dinitrobenzene results in decreased expression of CDC16 mRNA

NCBI chr 8:13,807,650...13,831,951
Ensembl chr 8:13,807,676...13,831,938

G

cell division cycle 20

decreases expression

3-dinitrobenzene results in decreased expression of CDC20 mRNA

NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549

G

CDC42 effector protein 3

decreases expression

3-dinitrobenzene results in decreased expression of CDC42EP3 mRNA

NCBI chr17:79,641,152...79,662,520
Ensembl chr17:79,641,156...79,662,520

G

cadherin 2

increases expression

3-dinitrobenzene results in increased expression of CDH2 mRNA

PMID:21983209 PMID:24140754

NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303

G

cyclin dependent kinase 1

decreases expression

3-dinitrobenzene results in decreased expression of CDK1 protein
3-dinitrobenzene results in decreased expression of CDK1 mRNA

PMID:19477251 PMID:22841810

NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768

G

cyclin dependent kinase 14

decreases expression

3-dinitrobenzene results in decreased expression of CDK14 mRNA

NCBI chr 5:4,853,384...5,430,650
Ensembl chr 5:4,853,391...5,470,312

G

cyclin dependent kinase 16

increases expression

3-dinitrobenzene results in increased expression of CDK16 mRNA

NCBI chr X:20,554,210...20,566,119
Ensembl chr X:20,554,193...20,566,119

G

cyclin dependent kinase 4

increases expression

3-dinitrobenzene results in increased expression of CDK4 mRNA

NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789

G

cyclin dependent kinase 5

increases expression

3-dinitrobenzene results in increased expression of CDK5 mRNA

NCBI chr 5:24,612,595...24,628,737
Ensembl chr 5:24,623,239...24,628,528

G

cyclin dependent kinase inhibitor 1A

increases expression

3-dinitrobenzene results in increased expression of CDKN1A protein

NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701

G

cyclin dependent kinase inhibitor 2D

increases expression

3-dinitrobenzene results in increased expression of CDKN2D mRNA

NCBI chr 9:21,199,759...21,202,553
Ensembl chr 9:21,199,706...21,202,703

G

centrosomal protein 70

decreases expression

3-dinitrobenzene results in decreased expression of CEP70 mRNA

NCBI chr 9:99,065,640...99,205,569
Ensembl chr 9:99,125,420...99,182,457

G

ceramide synthase 5

increases expression

3-dinitrobenzene results in increased expression of CERS5 mRNA

NCBI chr15:99,633,473...99,670,396
Ensembl chr15:99,632,762...99,670,766

G

cilia and flagella associated protein 410

decreases expression

3-dinitrobenzene results in decreased expression of CFAP410 mRNA

NCBI chr10:77,814,364...77,821,272
Ensembl chr10:77,814,358...77,822,739

G

CASP8 and FADD-like apoptosis regulator

increases expression

3-dinitrobenzene results in increased expression of CFLAR mRNA

NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043

G

cingulin

increases expression

3-dinitrobenzene results in increased expression of CGN mRNA

NCBI chr 3:94,667,376...94,695,036
Ensembl chr 3:94,667,376...94,693,826

G

checkpoint kinase 1

increases expression

3-dinitrobenzene results in increased expression of CHEK1 mRNA

NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361

G

cytokine induced apoptosis inhibitor 1

decreases expression

3-dinitrobenzene results in decreased expression of CIAPIN1 mRNA

NCBI chr 8:95,546,446...95,565,454
Ensembl chr 8:95,546,432...95,564,986

G

cytokine inducible SH2-containing protein

increases expression

3-dinitrobenzene results in increased expression of CISH mRNA

NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983

G

chemokine-like factor

decreases expression

3-dinitrobenzene results in decreased expression of CKLF mRNA

NCBI chr 8:104,977,493...104,992,642
Ensembl chr 8:104,977,493...104,991,570

G

claudin 5

decreases expression

3-dinitrobenzene results in decreased expression of CLDN5 mRNA

NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012

G

C-type lectin domain family 10, member A

increases expression

3-dinitrobenzene results in increased expression of CLEC10A mRNA

NCBI chr11:70,057,449...70,061,662
Ensembl chr11:70,047,023...70,061,660

G

C-type lectin domain family 4, member a1

increases expression

3-dinitrobenzene results in increased expression of CLEC4A1 mRNA

NCBI chr 6:122,898,807...122,911,578
Ensembl chr 6:122,898,807...122,911,578

G

COMM domain containing 1

decreases expression

3-dinitrobenzene results in decreased expression of COMMD1 mRNA

NCBI chr11:22,849,728...22,934,539
Ensembl chr11:22,846,136...22,932,382

G

cytochrome c oxidase subunit 6C

increases oxidation

3-dinitrobenzene results in increased oxidation of COX6C protein

NCBI chr15:35,932,122...35,938,392
Ensembl chr15:35,926,032...35,938,392

G

cytoplasmic polyadenylation element binding protein 2

decreases expression

3-dinitrobenzene results in decreased expression of CPEB2 mRNA

NCBI chr 5:43,382,692...43,447,067
Ensembl chr 5:43,390,513...43,447,067

G

carbamoyl-phosphate synthetase 1

decreases expression

3-dinitrobenzene results in decreased expression of CPS1 protein

NCBI chr 1:67,151,294...67,270,426
Ensembl chr 1:67,162,185...67,270,418

G

CREB3 regulatory factor

decreases expression

3-dinitrobenzene results in decreased expression of CREBRF mRNA

NCBI chr17:26,918,716...26,995,611
Ensembl chr17:26,934,624...26,995,609

G

centrosome and spindle pole associated protein 1

decreases expression

3-dinitrobenzene results in decreased expression of CSPP1 mRNA

NCBI chr 1:10,108,194...10,206,996
Ensembl chr 1:10,108,212...10,206,993

G

cleavage stimulation factor, 3' pre-RNA subunit 2, tau

decreases expression

3-dinitrobenzene results in decreased expression of CSTF2T mRNA

NCBI chr19:31,060,241...31,063,992
Ensembl chr19:31,060,237...31,064,469

G

CTD small phosphatase like

increases expression

3-dinitrobenzene results in increased expression of CTDSPL mRNA

NCBI chr 9:118,751,313...118,873,187
Ensembl chr 9:118,755,521...118,873,066

G

catenin alpha 1

increases expression

3-dinitrobenzene results in increased expression of CTNNA1 mRNA

PMID:21983209 PMID:24140754

NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832

G

catenin beta 1

increases expression

3-dinitrobenzene results in increased expression of CTNNB1 mRNA

NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573

G

cutC copper transporter

decreases expression

3-dinitrobenzene results in decreased expression of CUTC mRNA

NCBI chr19:43,741,462...43,757,077
Ensembl chr19:43,741,435...43,757,077

G

C-X-C motif chemokine ligand 9

increases expression

3-dinitrobenzene results in increased expression of CXCL9 mRNA

NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938

G

cytochrome P450, family 11, subfamily a, polypeptide 1

decreases expression

3-dinitrobenzene results in decreased expression of CYP11A1 mRNA

NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases expression

3-dinitrobenzene results in decreased expression of CYP17A1 mRNA

NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611

G

cytochrome P450, family 46, subfamily a, polypeptide 1

increases expression

3-dinitrobenzene results in increased expression of CYP46A1 mRNA

NCBI chr12:108,300,568...108,328,497
Ensembl chr12:108,300,640...108,328,493

G

DDB1 and CUL4 associated factor 6

decreases expression

3-dinitrobenzene results in decreased expression of DCAF6 mRNA

NCBI chr 1:165,157,069...165,288,475
Ensembl chr 1:165,156,267...165,288,044

G

doublecortin domain containing 2a

decreases expression

3-dinitrobenzene results in decreased expression of DCDC2 mRNA

NCBI chr13:25,239,126...25,394,689
Ensembl chr13:25,239,987...25,394,689

G

damage specific DNA binding protein 1

increases expression

3-dinitrobenzene results in increased expression of DDB1 mRNA

NCBI chr19:10,582,961...10,607,186
Ensembl chr19:10,582,691...10,607,183

G

DDHD domain containing 1

increases expression

3-dinitrobenzene results in increased expression of DDHD1 mRNA

NCBI chr14:45,830,628...45,895,600
Ensembl chr14:45,825,924...45,895,600

G

DNA-damage-inducible transcript 4

increases expression

3-dinitrobenzene results in increased expression of DDIT4 mRNA

NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656

G

DEAD box helicase 28

decreases expression

3-dinitrobenzene results in decreased expression of DDX28 mRNA

NCBI chr 8:106,736,248...106,738,118
Ensembl chr 8:106,736,253...106,738,514

G

DEP domain containing 1B

decreases expression

3-dinitrobenzene results in decreased expression of DEPDC1B mRNA

NCBI chr13:108,452,592...108,526,100
Ensembl chr13:108,452,866...108,544,316

G

DIX domain containing 1

decreases expression

3-dinitrobenzene results in decreased expression of DIXDC1 mRNA

NCBI chr 9:50,574,052...50,650,900
Ensembl chr 9:50,574,052...50,650,817

G

dihydrolipoamide dehydrogenase

multiple interactions

[5-methoxyindole-2-carboxylic acid results in decreased activity of DLD protein] inhibits the reaction [3-dinitrobenzene results in decreased abundance of Thioctic Acid]

NCBI chr12:31,381,561...31,401,470
Ensembl chr12:31,381,276...31,401,452

G

distal membrane arm assembly component 2 like

decreases expression

3-dinitrobenzene results in decreased expression of DMAC2L mRNA

NCBI chr12:69,771,687...69,791,439
Ensembl chr12:69,771,724...69,791,434

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

decreases expression

3-dinitrobenzene results in decreased expression of DNPH1 mRNA

NCBI chr17:46,807,715...46,810,544
Ensembl chr17:46,807,637...46,810,550

G

dihydropyrimidinase-like 4

increases expression

3-dinitrobenzene results in increased expression of DPYSL4 mRNA

NCBI chr 7:138,665,917...138,681,711
Ensembl chr 7:138,665,917...138,682,620

G

down-regulator of transcription 1

decreases expression

3-dinitrobenzene results in decreased expression of DR1 mRNA

NCBI chr 5:108,416,763...108,428,387
Ensembl chr 5:108,416,763...108,428,392

G

dystrobrevin binding protein 1

decreases expression

3-dinitrobenzene results in decreased expression of DTNBP1 mRNA

NCBI chr13:45,075,552...45,155,614
Ensembl chr13:45,075,551...45,155,623

G

dual specificity phosphatase 23

decreases expression

3-dinitrobenzene results in decreased expression of DUSP23 protein

NCBI chr 1:172,458,336...172,460,504
Ensembl chr 1:172,458,331...172,460,529

G

dual specificity phosphatase 5

increases expression

3-dinitrobenzene results in increased expression of DUSP5 mRNA

NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862

G

dual specificity phosphatase 6

increases expression

3-dinitrobenzene results in increased expression of DUSP6 mRNA

NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351

G

dynein cytoplasmic 1 heavy chain 1

increases oxidation

3-dinitrobenzene results in increased oxidation of DYNC1H1 protein

NCBI chr12:110,567,829...110,633,378
Ensembl chr12:110,567,886...110,633,379

G

emopamil binding protein-like

decreases expression

3-dinitrobenzene results in decreased expression of EBPL mRNA

NCBI chr14:61,577,212...61,597,894
Ensembl chr14:61,569,191...61,597,888

G

enoyl Coenzyme A hydratase domain containing 1

affects expression

3-dinitrobenzene affects the expression of ECHDC1 mRNA

NCBI chr10:29,174,140...29,222,657
Ensembl chr10:29,189,162...29,223,465

G

endothelin 1

increases expression

3-dinitrobenzene results in increased expression of EDN1 mRNA

NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466

G

EH-domain containing 1

increases expression

3-dinitrobenzene results in increased expression of EHD1 mRNA

NCBI chr19:6,326,926...6,350,126
Ensembl chr19:6,326,755...6,350,126

G

etoposide induced 2.4 mRNA

increases expression

3-dinitrobenzene results in increased expression of EI24 mRNA

NCBI chr 9:36,690,449...36,708,630
Ensembl chr 9:36,690,455...36,708,689

G

endosomal transmembrane epsin interactor 1

increases expression

3-dinitrobenzene results in increased expression of ENTREP1 mRNA

NCBI chr19:23,950,114...24,008,800
Ensembl chr19:23,950,114...24,008,383

G

Eph receptor A4

decreases expression

3-dinitrobenzene results in decreased expression of EPHA4 mRNA

NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725

G

ets variant 5

increases expression

3-dinitrobenzene results in increased expression of ETV5 mRNA

NCBI chr16:22,200,063...22,258,320
Ensembl chr16:22,200,059...22,258,469

G

coagulation factor II

affects expression

3-dinitrobenzene affects the expression of F2 mRNA

NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759

G

coagulation factor VIII

decreases expression

3-dinitrobenzene results in decreased expression of F8 mRNA

NCBI chr X:74,213,950...74,426,342
Ensembl chr X:74,216,321...74,426,221

G

fatty acid binding protein 9, testis

decreases expression

3-dinitrobenzene results in decreased expression of FABP9 protein

NCBI chr 3:10,258,683...10,262,343
Ensembl chr 3:10,258,681...10,262,343

G

phenylalanine-tRNA synthetase 2, mitochondrial

decreases expression

3-dinitrobenzene results in decreased expression of FARS2 protein

NCBI chr13:36,301,373...36,721,569
Ensembl chr13:36,301,395...36,910,254

G

f-box protein 9

decreases expression

3-dinitrobenzene results in decreased expression of FBXO9 mRNA

NCBI chr 9:77,988,781...78,016,347
Ensembl chr 9:77,988,781...78,016,347

G

fermitin family member 1

decreases expression

3-dinitrobenzene results in decreased expression of FERMT1 protein

NCBI chr 2:132,746,097...132,787,956
Ensembl chr 2:132,746,309...132,787,826

G

fermitin family member 2

increases expression

3-dinitrobenzene results in increased expression of FERMT2 mRNA

NCBI chr14:45,696,252...45,767,767
Ensembl chr14:45,696,252...45,767,575

G

Friend leukemia integration 1

increases expression

3-dinitrobenzene results in increased expression of FLI1 mRNA

NCBI chr 9:32,333,500...32,454,292
Ensembl chr 9:32,333,500...32,454,157

G

formin binding protein 1

increases expression

3-dinitrobenzene results in increased expression of FNBP1 mRNA

PMID:21983209 PMID:24140754

NCBI chr 2:30,916,218...31,032,046
Ensembl chr 2:30,916,218...31,032,020

G

forkhead box P2

decreases expression

3-dinitrobenzene results in decreased expression of FOXP2 mRNA

NCBI chr 6:14,901,348...15,441,976
Ensembl chr 6:14,901,348...15,441,976

G

fibroblast growth factor receptor substrate 3

decreases expression

3-dinitrobenzene results in decreased expression of FRS3 mRNA

NCBI chr17:47,998,532...48,015,211
Ensembl chr17:47,999,955...48,015,211

G

fucosyltransferase 2

increases expression

3-dinitrobenzene results in increased expression of FUT2 mRNA

NCBI chr 7:45,298,015...45,315,818
Ensembl chr 7:45,298,015...45,315,818

G

growth arrest and DNA-damage-inducible 45 gamma

increases expression

3-dinitrobenzene results in increased expression of GADD45G mRNA

NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504

G

polypeptide N-acetylgalactosaminyltransferase 6

increases expression

3-dinitrobenzene results in increased expression of GALNT6 mRNA

NCBI chr15:100,587,796...100,627,257
Ensembl chr15:100,589,694...100,627,257

G

glyceraldehyde-3-phosphate dehydrogenase

increases oxidation

3-dinitrobenzene results in increased oxidation of GAPDH protein

NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430

G

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

decreases expression

3-dinitrobenzene results in decreased expression of GAPDHS protein

NCBI chr 7:30,429,204...30,443,106
Ensembl chr 7:30,429,200...30,443,106

G

guanylate binding protein 2

increases expression

3-dinitrobenzene results in increased expression of GBP2 mRNA

NCBI chr 3:142,326,424...142,343,769
Ensembl chr 3:142,326,363...142,343,769

G

guanylate binding protein 3

increases expression

3-dinitrobenzene results in increased expression of GBP4 mRNA

NCBI chr 3:142,265,781...142,278,974
Ensembl chr 3:142,265,787...142,278,970

G

gap junction protein, alpha 1

decreases expression

3-dinitrobenzene results in decreased expression of GJA1 protein; 3-dinitrobenzene results in decreased expression of GJA1 protein modified form

NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609

G

gap junction protein, beta 6

decreases expression

3-dinitrobenzene results in decreased expression of GJB6 mRNA

NCBI chr14:57,360,760...57,370,764
Ensembl chr14:57,360,760...57,371,068

G

guanosine monophosphate reductase 2

decreases expression

3-dinitrobenzene results in decreased expression of GMPR2 mRNA

NCBI chr14:55,909,692...55,935,602
Ensembl chr14:55,909,398...55,916,657

G

guanine nucleotide binding protein, alpha 14

increases expression

3-dinitrobenzene results in increased expression of GNA14 mRNA

NCBI chr19:16,413,031...16,590,706
Ensembl chr19:16,413,126...16,588,184

G

golgi associated PDZ and coiled-coil motif containing

decreases expression

3-dinitrobenzene results in decreased expression of GOPC mRNA

NCBI chr10:52,213,120...52,258,220
Ensembl chr10:52,211,946...52,258,220

G

G protein-coupled receptor 61

decreases expression

3-dinitrobenzene results in decreased expression of GPR61 mRNA

NCBI chr 3:108,055,660...108,062,218
Ensembl chr 3:108,055,637...108,062,198

G

gelsolin

increases expression

3-dinitrobenzene results in increased expression of GSN mRNA

NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904

G

glutathione S-transferase kappa 1

increases oxidation

3-dinitrobenzene results in increased oxidation of GSTK1 protein

NCBI chr 6:42,222,869...42,227,375
Ensembl chr 6:42,222,869...42,227,381

G

glutathione S-transferase, pi 1

increases expression

3-dinitrobenzene results in increased expression of GSTP1 mRNA

NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985

G

H2A clustered histone 25

decreases expression

3-dinitrobenzene results in decreased expression of H2AC25 mRNA

NCBI chr11:58,845,511...58,846,018
Ensembl chr11:58,845,511...58,847,656

G

H2A.X variant histone

decreases expression

3-dinitrobenzene results in decreased expression of H2AX mRNA

NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374

G

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1

decreases expression

3-dinitrobenzene results in decreased expression of HACE1 mRNA

NCBI chr10:45,453,911...45,588,441
Ensembl chr10:45,453,925...45,588,441

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases oxidation

3-dinitrobenzene results in increased oxidation of HADHB protein

NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591

G

hemicentin 1

decreases expression

3-dinitrobenzene results in decreased expression of HMCN1 mRNA

NCBI chr 1:150,438,251...150,869,568
Ensembl chr 1:150,438,275...150,869,186

G

heme oxygenase 1

increases expression

3-dinitrobenzene results in increased expression of HMOX1 mRNA

NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217

G

HPS6, biogenesis of lysosomal organelles complex 2 subunit 3

increases expression

3-dinitrobenzene results in increased expression of HPS6 mRNA

NCBI chr19:45,991,917...45,994,612
Ensembl chr19:45,991,947...45,994,612

G

heat shock protein 90, beta (Grp94), member 1

increases metabolic processing

3-dinitrobenzene results in increased metabolism of HSP90B1 protein

NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373

G

heat shock protein 5

increases metabolic processing

3-dinitrobenzene results in increased metabolism of HSPA5 protein

NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559

G

heat shock protein 8

decreases expression

3-dinitrobenzene results in decreased expression of HSPB8 mRNA

NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923

G

inhibitor of DNA binding 4

decreases expression

3-dinitrobenzene results in decreased expression of ID4 mRNA

NCBI chr13:48,414,592...48,419,504
Ensembl chr13:48,414,704...48,419,502

G

immediate early response 3

increases expression
affects expression

3-dinitrobenzene results in increased expression of IER3 mRNA
3-dinitrobenzene affects the expression of IER3 mRNA

PMID:21983209 PMID:24140754

NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815

G

interferon-induced protein 44 like

increases expression

3-dinitrobenzene results in increased expression of IFI44L mRNA

NCBI chr 3:151,464,374...151,468,528
Ensembl chr 3:151,464,374...151,468,529

G

interleukin 1 alpha

increases expression

3-dinitrobenzene results in increased expression of IL1A mRNA

NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892

G

interleukin 6 receptor, alpha

increases expression

3-dinitrobenzene results in increased expression of IL6R mRNA

NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503

G

integrin beta 1 (fibronectin receptor beta)

increases expression

3-dinitrobenzene results in increased expression of ITGB1 mRNA

PMID:21983209 PMID:24140754

NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681

G

inter alpha-trypsin inhibitor, heavy chain 4

increases expression

3-dinitrobenzene results in increased expression of ITIH4 mRNA

NCBI chr14:30,608,433...30,623,943
Ensembl chr14:30,608,433...30,624,310

G

junction adhesion molecule 2

increases expression

3-dinitrobenzene results in increased expression of JAM2 mRNA

NCBI chr16:84,571,011...84,623,268
Ensembl chr16:84,571,011...84,622,816

G

potassium voltage-gated channel, Shal-related family, member 1

increases expression

3-dinitrobenzene results in increased expression of KCND1 mRNA

NCBI chr X:7,686,907...7,704,517
Ensembl chr X:7,688,528...7,704,519

G

Kv channel-interacting protein 1

affects expression

3-dinitrobenzene affects the expression of KCNIP1 mRNA

NCBI chr11:33,579,339...33,943,854
Ensembl chr11:33,579,339...33,943,152

G

potassium inwardly-rectifying channel, subfamily K, member 6

increases expression

3-dinitrobenzene results in increased expression of KCNK6 mRNA

NCBI chr 7:28,921,353...28,931,947
Ensembl chr 7:28,921,351...28,931,940

G

kinase D-interacting substrate 220

decreases expression

3-dinitrobenzene results in decreased expression of KIDINS220 mRNA

NCBI chr12:25,024,909...25,113,151
Ensembl chr12:25,024,924...25,113,151

G

keratin 10

decreases expression

3-dinitrobenzene results in decreased expression of KRT10 protein

NCBI chr11:99,276,080...99,288,631
Ensembl chr11:99,276,080...99,280,190

G

keratin 19

increases expression

3-dinitrobenzene results in increased expression of KRT19 mRNA

NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491

G

laminin gamma 3

increases expression

3-dinitrobenzene results in increased expression of LAMC3 mRNA

NCBI chr 2:31,777,293...31,839,095
Ensembl chr 2:31,777,303...31,836,551

G

lymphoid enhancer binding factor 1

decreases expression

3-dinitrobenzene results in decreased expression of LEF1 mRNA

NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005

G

luteinizing hormone beta

decreases expression

3-dinitrobenzene results in decreased expression of LHB mRNA

NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321

G

luteinizing hormone/choriogonadotropin receptor

increases expression

3-dinitrobenzene results in increased expression of LHCGR mRNA

NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418

G

leukemia inhibitory factor

increases expression

3-dinitrobenzene results in increased expression of LIF mRNA

NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514

G

leucine rich repeat containing 23

increases expression

3-dinitrobenzene results in increased expression of LRRC23 protein

NCBI chr 6:124,746,832...124,757,411
Ensembl chr 6:124,746,826...124,756,690

G

U7 snRNP-specific Sm-like protein LSM11

decreases expression

3-dinitrobenzene results in decreased expression of LSM11 mRNA

NCBI chr11:45,819,096...45,835,762
Ensembl chr11:45,819,096...45,835,762

G

lipolysis stimulated lipoprotein receptor

increases expression

3-dinitrobenzene results in increased expression of LSR mRNA

NCBI chr 7:30,657,195...30,672,894
Ensembl chr 7:30,657,195...30,672,889

G

macroH2A.2 histone

decreases expression

3-dinitrobenzene results in decreased expression of MACROH2A2 mRNA

NCBI chr10:61,574,419...61,620,383
Ensembl chr10:61,574,444...61,619,926

G

mannosidase 2, alpha 2

decreases expression

3-dinitrobenzene results in decreased expression of MAN2A2 mRNA

NCBI chr 7:79,998,843...80,021,222
Ensembl chr 7:79,998,845...80,021,123

G

mitogen-activated protein kinase kinase kinase 8

increases expression

3-dinitrobenzene results in increased expression of MAP3K8 mRNA

NCBI chr18:4,331,325...4,352,978
Ensembl chr18:4,331,327...4,353,015

G

mitogen-activated protein kinase 1

increases phosphorylation

3-dinitrobenzene results in increased phosphorylation of MAPK1 protein

NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317

G

mitogen-activated protein kinase 15

decreases expression

3-dinitrobenzene results in decreased expression of MAPK15 mRNA

NCBI chr15:75,865,581...75,871,002
Ensembl chr15:75,865,618...75,871,003

G

mitogen-activated protein kinase 3

increases phosphorylation

3-dinitrobenzene results in increased phosphorylation of MAPK3 protein

NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991

G

membrane associated ring-CH-type finger 3

decreases expression

3-dinitrobenzene results in decreased expression of MARCHF3 mRNA

NCBI chr18:56,894,788...57,058,587
Ensembl chr18:56,894,788...57,058,620

G

muscleblind like splicing factor 3

increases expression

3-dinitrobenzene results in increased expression of MBNL3 mRNA

NCBI chr X:50,202,371...50,294,867
Ensembl chr X:50,206,146...50,295,409

G

methyltransferase 6, methylcytidine

decreases expression

3-dinitrobenzene results in decreased expression of METTL6 mRNA

NCBI chr14:31,180,775...31,217,007
Ensembl chr14:31,195,535...31,216,997

G

mitochondrial calcium uptake family, member 3

decreases expression

3-dinitrobenzene results in decreased expression of MICU3 mRNA

NCBI chr 8:40,760,394...40,841,824
Ensembl chr 8:40,760,499...40,839,349

G

myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10

decreases expression

3-dinitrobenzene results in decreased expression of MLLT10 mRNA

NCBI chr 2:18,059,971...18,217,201
Ensembl chr 2:18,060,048...18,217,199

G

myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3

increases expression

3-dinitrobenzene results in increased expression of MLLT3 mRNA

NCBI chr 4:87,688,162...87,951,652
Ensembl chr 4:87,688,162...87,951,601

G

MRS2 magnesium transporter

decreases expression

3-dinitrobenzene results in decreased expression of MRS2 mRNA

NCBI chr13:25,171,466...25,204,345
Ensembl chr13:25,171,466...25,204,362

G

methionine sulfoxide reductase B2

decreases expression

3-dinitrobenzene results in decreased expression of MSRB2 mRNA

NCBI chr 2:19,376,247...19,399,787
Ensembl chr 2:19,376,251...19,399,787

G

5, 10-methenyltetrahydrofolate synthetase

increases expression

3-dinitrobenzene results in increased expression of MTHFS mRNA

NCBI chr 9:89,093,243...89,122,278
Ensembl chr 9:89,092,729...89,259,766

G

myosin, light polypeptide kinase

increases expression

3-dinitrobenzene results in increased expression of MYLK mRNA

NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790

G

N(alpha)-acetyltransferase 40, NatD catalytic subunit

decreases expression

3-dinitrobenzene results in decreased expression of NAA40 mRNA

NCBI chr19:7,203,033...7,218,587
Ensembl chr19:7,203,033...7,218,548

G

Ngfi-A binding protein 2

increases expression

3-dinitrobenzene results in increased expression of NAB2 mRNA

NCBI chr10:127,496,787...127,502,572
Ensembl chr10:127,496,787...127,504,437

G

NADH:ubiquinone oxidoreductase subunit A6

increases oxidation

3-dinitrobenzene results in increased oxidation of NDUFA6 protein

NCBI chr15:82,234,342...82,238,438
Ensembl chr15:82,234,341...82,238,523

G

nectin cell adhesion molecule 2

increases expression

3-dinitrobenzene results in increased expression of NECTIN2 mRNA

NCBI chr 7:19,450,569...19,483,498
Ensembl chr 7:19,450,569...19,484,408

G

nectin cell adhesion molecule 3

decreases expression

3-dinitrobenzene results in decreased expression of NECTIN3 mRNA

NCBI chr16:46,208,028...46,318,898
Ensembl chr16:46,208,069...46,318,888

G

nestin

affects expression

3-dinitrobenzene affects the expression of NES mRNA

NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758

G

nidogen 1

increases expression

3-dinitrobenzene results in increased expression of NID1 mRNA

NCBI chr13:13,612,252...13,686,849
Ensembl chr13:13,612,136...13,686,854

G

nitrilase 1

decreases expression

3-dinitrobenzene results in decreased expression of NIT1 protein

NCBI chr 1:171,168,145...171,173,209
Ensembl chr 1:171,165,576...171,173,214

G

nucleolar protein 4

decreases expression

3-dinitrobenzene results in decreased expression of NOL4 mRNA

NCBI chr18:22,826,209...23,174,926
Ensembl chr18:22,826,238...23,174,710

G

nitric oxide synthase 3, endothelial cell

increases expression

3-dinitrobenzene results in increased expression of NOS3 mRNA

NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472

G

neuronal PAS domain protein 1

increases expression

3-dinitrobenzene results in increased expression of NPAS1 mRNA

NCBI chr 7:16,189,643...16,210,741
Ensembl chr 7:16,189,646...16,211,653

G

nuclear receptor interacting protein 3

decreases expression

3-dinitrobenzene results in decreased expression of NRIP3 mRNA

NCBI chr 7:109,357,263...109,380,752
Ensembl chr 7:109,357,262...109,381,232

G

netrin 5

decreases expression

3-dinitrobenzene results in decreased expression of NTN5 mRNA

NCBI chr 7:45,333,519...45,343,980
Ensembl chr 7:45,333,446...45,343,980

G

nucleoporin 210

increases expression

3-dinitrobenzene results in increased expression of NUP210 mRNA

NCBI chr 6:90,990,049...91,095,920
Ensembl chr 6:90,990,050...91,093,811

G

nucleoredoxin

increases expression

3-dinitrobenzene results in increased expression of NXN mRNA

NCBI chr11:76,148,052...76,289,967
Ensembl chr11:76,148,024...76,289,966

G

obscurin-like 1

increases expression

3-dinitrobenzene results in increased expression of OBSL1 mRNA

NCBI chr 1:75,462,469...75,483,134
Ensembl chr 1:75,455,954...75,483,096

G

3-oxoacid CoA transferase 1

increases oxidation

3-dinitrobenzene results in increased oxidation of OXCT1 protein

NCBI chr15:4,055,910...4,184,826
Ensembl chr15:4,055,865...4,184,826

G

prolyl 3-hydroxylase family member 4 (non-enzymatic)

increases expression

3-dinitrobenzene results in increased expression of P3H4 mRNA

NCBI chr11:100,299,293...100,305,542
Ensembl chr11:100,299,282...100,305,662

G

prolyl 4-hydroxylase, beta polypeptide

increases metabolic processing

3-dinitrobenzene results in increased metabolism of P4HB protein

NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079

G

palladin, cytoskeletal associated protein

increases expression

3-dinitrobenzene results in increased expression of PALLD mRNA

NCBI chr 8:61,964,465...62,355,741
Ensembl chr 8:61,964,467...62,355,724

G

poly (ADP-ribose) polymerase family, member 1

increases cleavage
multiple interactions

3-dinitrobenzene results in increased cleavage of PARP1 protein
pyrazolanthrone inhibits the reaction [3-dinitrobenzene results in increased cleavage of PARP1 protein]

NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819

G

poly (ADP-ribose) polymerase family, member 2

decreases expression

3-dinitrobenzene results in decreased expression of PARP2 mRNA

NCBI chr14:51,045,347...51,058,758
Ensembl chr14:51,045,298...51,058,758

G

PAS domain containing serine/threonine kinase

decreases expression

3-dinitrobenzene results in decreased expression of PASK mRNA

NCBI chr 1:93,237,165...93,271,237
Ensembl chr 1:93,236,492...93,271,204

G

PDZ binding kinase

decreases expression
affects expression

3-dinitrobenzene results in decreased expression of PBK mRNA
3-dinitrobenzene affects the expression of PBK mRNA

PMID:21983209 PMID:24140754

NCBI chr14:66,043,337...66,055,271
Ensembl chr14:66,043,286...66,055,271

G

protocadherin 8

decreases expression

3-dinitrobenzene results in decreased expression of PCDH8 mRNA

NCBI chr14:80,004,224...80,008,752
Ensembl chr14:80,004,215...80,008,752

G

proprotein convertase subtilisin/kexin type 1

increases expression

3-dinitrobenzene results in increased expression of PCSK1 mRNA

NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980

G

phosphodiesterase 4D interacting protein (myomegalin)

decreases expression

3-dinitrobenzene results in decreased expression of PDE4DIP mRNA

NCBI chr 3:97,597,144...97,796,023
Ensembl chr 3:97,597,140...97,796,023

G

protein disulfide isomerase associated 3

increases expression
increases metabolic processing

3-dinitrobenzene results in increased expression of PDIA3 mRNA
3-dinitrobenzene results in increased metabolism of PDIA3 protein

PMID:21402099 PMID:21983209

NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168

G

pyridoxal (pyridoxine, vitamin B6) phosphatase

decreases expression

3-dinitrobenzene results in decreased expression of PDXP protein

NCBI chr15:78,796,342...78,803,717
Ensembl chr15:78,798,119...78,803,717

G

prodynorphin

increases expression

3-dinitrobenzene results in increased expression of PDYN mRNA

NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764

G

proliferation and apoptosis adaptor protein 15A

increases expression

3-dinitrobenzene results in increased expression of PEA15A mRNA

NCBI chr 1:172,024,295...172,034,298
Ensembl chr 1:172,024,295...172,034,371

G

phosphoglucomutase 2-like 1

decreases expression

3-dinitrobenzene results in decreased expression of PGM2L1 mRNA

NCBI chr 7:99,876,471...99,928,079
Ensembl chr 7:99,876,601...99,928,075

G

PHD finger protein 2

decreases expression

3-dinitrobenzene results in decreased expression of PHF2 mRNA

PMID:21983209 PMID:24140754

NCBI chr13:48,955,226...49,024,361
Ensembl chr13:48,955,226...49,024,595

G

peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1

decreases expression

3-dinitrobenzene results in decreased expression of PIN1 protein

NCBI chr 9:20,563,335...20,575,008
Ensembl chr 9:20,563,391...20,577,880

G

pirin

increases expression

3-dinitrobenzene results in increased expression of PIR mRNA

NCBI chr X:163,052,427...163,156,009
Ensembl chr X:163,052,367...163,156,007

G

paired-like homeodomain transcription factor 2

decreases expression

3-dinitrobenzene results in decreased expression of PITX2 mRNA

PMID:22841810 PMID:24140754

NCBI chr 3:128,993,527...129,013,243
Ensembl chr 3:128,993,527...129,013,240

G

protein kinase inhibitor beta, cAMP dependent, testis specific

decreases expression

3-dinitrobenzene results in decreased expression of PKIB mRNA

NCBI chr10:57,508,077...57,617,208
Ensembl chr10:57,508,077...57,617,208

G

phospholipase C, beta 4

decreases expression

3-dinitrobenzene results in decreased expression of PLCB4 protein

NCBI chr 2:135,500,523...135,856,522
Ensembl chr 2:135,500,931...135,856,513

G

perilipin 2

increases expression

3-dinitrobenzene results in increased expression of PLIN2 mRNA

NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297

G

polo like kinase 1

decreases expression

3-dinitrobenzene results in decreased expression of PLK1 mRNA

NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096

G

polo like kinase 2

increases expression

3-dinitrobenzene results in increased expression of PLK2 mRNA

NCBI chr13:110,531,578...110,537,378
Ensembl chr13:110,531,580...110,537,378

G

polymerase (DNA directed), beta

decreases expression

3-dinitrobenzene results in decreased expression of POLB mRNA

NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451

G

polymerase (RNA) III (DNA directed) polypeptide K

decreases expression

3-dinitrobenzene results in decreased expression of POLR3K mRNA

NCBI chr 2:181,506,153...181,512,623
Ensembl chr 2:181,506,130...181,512,623

G

paraoxonase 2

increases expression

3-dinitrobenzene results in increased expression of PON2 mRNA

NCBI chr 6:5,264,620...5,298,408
Ensembl chr 6:5,264,147...5,298,455

G

pancreatic progenitor cell differentiation and proliferation factor

increases expression

3-dinitrobenzene results in increased expression of PPDPF mRNA

NCBI chr 2:180,828,615...180,830,297
Ensembl chr 2:180,829,040...180,830,564

G

protein phosphatase 1H (PP2C domain containing)

increases expression

3-dinitrobenzene results in increased expression of PPM1H mRNA

NCBI chr10:122,512,720...122,781,700
Ensembl chr10:122,514,667...122,781,700

G

protein phosphatase 1 catalytic subunit alpha

decreases expression

3-dinitrobenzene results in decreased expression of PPP1CA protein

NCBI chr19:4,242,173...4,245,418
Ensembl chr19:4,242,064...4,245,419

G

protein phosphatase 2, regulatory subunit A, beta

decreases expression

3-dinitrobenzene results in decreased expression of PPP2R1B mRNA

NCBI chr 9:50,767,946...50,810,625
Ensembl chr 9:50,756,601...50,805,529

G

protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)

increases expression

3-dinitrobenzene results in increased expression of PPP3R1 mRNA

NCBI chr11:17,109,298...17,150,380
Ensembl chr11:17,109,263...17,150,375

G

protein arginine N-methyltransferase 2

decreases expression

3-dinitrobenzene results in decreased expression of PRMT2 mRNA

NCBI chr10:76,043,060...76,073,699
Ensembl chr10:76,043,056...76,073,699

G

prokineticin 2

decreases expression

3-dinitrobenzene results in decreased expression of PROK2 mRNA

NCBI chr 6:99,687,833...99,703,368
Ensembl chr 6:99,688,260...99,703,353

G

PC4 and SFRS1 interacting protein 1

decreases expression

3-dinitrobenzene results in decreased expression of PSIP1 mRNA

NCBI chr 4:83,373,917...83,404,700
Ensembl chr 4:83,373,917...83,404,696

G

proteasome subunit alpha 3

increases expression

3-dinitrobenzene results in increased expression of PSMA3 mRNA

NCBI chr12:71,016,082...71,042,651
Ensembl chr12:71,021,395...71,043,121

G

proteasome subunit alpha 4

increases expression

3-dinitrobenzene results in increased expression of PSMA4 mRNA

NCBI chr 9:54,858,074...54,865,316
Ensembl chr 9:54,858,074...54,865,314

G

proteasome subunit alpha 5

increases expression

3-dinitrobenzene results in increased expression of PSMA5 mRNA

NCBI chr 3:108,164,242...108,187,268
Ensembl chr 3:108,164,242...108,187,290

G

proteasome (prosome, macropain) subunit, beta type 1

affects expression

3-dinitrobenzene affects the expression of PSMB1 mRNA

NCBI chr17:15,695,983...15,718,538
Ensembl chr17:15,695,283...15,720,013

G

proteasome (prosome, macropain) subunit, beta type 10

affects expression

3-dinitrobenzene affects the expression of PSMB10 mRNA

NCBI chr 8:106,662,360...106,665,024
Ensembl chr 8:106,662,367...106,665,076

G

proteasome (prosome, macropain) subunit, beta type 2

affects expression
increases expression
decreases expression

3-dinitrobenzene affects the expression of PSMB2 mRNA
3-dinitrobenzene results in increased expression of PSMB2 mRNA
3-dinitrobenzene results in decreased expression of PSMB2 protein

PMID:16988215 PMID:24140754

NCBI chr 4:126,571,460...126,603,503
Ensembl chr 4:126,571,423...126,603,507

G

proteasome (prosome, macropain) subunit, beta type 5

affects expression

3-dinitrobenzene affects the expression of PSMB5 mRNA

NCBI chr14:54,851,577...54,855,452
Ensembl chr14:54,851,576...54,855,479

G

proteasome (prosome, macropain) subunit, beta type 6

increases expression

3-dinitrobenzene results in increased expression of PSMB6 mRNA

NCBI chr11:70,416,116...70,418,684
Ensembl chr11:70,416,193...70,418,684

G

proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)

affects expression

3-dinitrobenzene affects the expression of PSMB8 mRNA

NCBI chr17:34,417,169...34,420,428
Ensembl chr17:34,416,695...34,420,428

G

proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)

affects expression

3-dinitrobenzene affects the expression of PSMB9 mRNA

NCBI chr17:34,401,006...34,406,347
Ensembl chr17:34,400,961...34,406,738

G

PTK7 protein tyrosine kinase 7

increases expression

3-dinitrobenzene results in increased expression of PTK7 mRNA

NCBI chr17:46,875,377...46,940,975
Ensembl chr17:46,875,397...46,940,430

G

protein tyrosine phosphatase, non-receptor type 3

increases expression

3-dinitrobenzene results in increased expression of PTPN3 mRNA

NCBI chr 4:57,190,841...57,339,036
Ensembl chr 4:57,190,841...57,301,837

G

protein tyrosine phosphatase, non-receptor type 7

increases expression

3-dinitrobenzene results in increased expression of PTPN7 mRNA

NCBI chr 1:135,059,577...135,073,064
Ensembl chr 1:135,060,438...135,073,055

G

protein tyrosine phosphatase receptor type F

increases expression

3-dinitrobenzene results in increased expression of PTPRF mRNA

NCBI chr 4:118,065,410...118,148,602
Ensembl chr 4:118,065,410...118,148,602

G

pituitary tumor-transforming gene 1

decreases expression

3-dinitrobenzene results in decreased expression of PTTG1 mRNA

NCBI chr11:43,311,097...43,317,417
Ensembl chr11:43,311,077...43,317,078

G

RAB20, member RAS oncogene family

increases expression

3-dinitrobenzene results in increased expression of RAB20 mRNA

NCBI chr 8:11,503,390...11,528,640
Ensembl chr 8:11,503,518...11,528,710

G

RAB5C, member RAS oncogene family

increases expression

3-dinitrobenzene results in increased expression of RAB5C mRNA

NCBI chr11:100,605,829...100,629,041
Ensembl chr11:100,605,835...100,629,041

G

RAD50 double strand break repair protein

decreases expression

3-dinitrobenzene results in decreased expression of RAD50 mRNA

NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146

G

ribonucleic acid export 1

increases expression

3-dinitrobenzene results in increased expression of RAE1 mRNA

NCBI chr 2:172,841,909...172,857,532
Ensembl chr 2:172,841,910...172,857,532

G

RNA guanine-7 methyltransferase activating subunit

decreases expression

3-dinitrobenzene results in decreased expression of RAMAC mRNA

NCBI chr 7:81,412,701...81,419,238
Ensembl chr 7:81,412,673...81,419,239

G

RAS, dexamethasone-induced 1

increases expression

3-dinitrobenzene results in increased expression of RASD1 mRNA

NCBI chr11:59,854,007...59,855,770
Ensembl chr11:59,854,007...59,855,770

G

RAS-like, family 11, member B

increases expression

3-dinitrobenzene results in increased expression of RASL11B mRNA

NCBI chr 5:74,355,987...74,360,138
Ensembl chr 5:74,355,947...74,360,142

G

RNA binding motif protein 20

decreases expression

3-dinitrobenzene results in decreased expression of RBM20 mRNA

NCBI chr19:53,649,422...53,855,514
Ensembl chr19:53,665,737...53,855,511

G

RNA binding motif protein, X chromosome

increases expression

3-dinitrobenzene results in increased expression of RBMX mRNA

NCBI chr X:56,428,708...56,438,405
Ensembl chr X:56,428,890...56,438,396

G

regulator of calcineurin 1

increases expression

3-dinitrobenzene results in increased expression of RCAN1 mRNA

NCBI chr16:92,188,839...92,263,057
Ensembl chr16:92,188,841...92,267,755

G

retroelement silencing factor 1

decreases expression

3-dinitrobenzene results in decreased expression of RESF1 mRNA

PMID:21983209 PMID:24140754

NCBI chr 6:149,210,907...149,237,161
Ensembl chr 6:149,210,912...149,237,161

G

regulatory factor X, 4 (influences HLA class II expression)

decreases expression

3-dinitrobenzene results in decreased expression of RFX4 mRNA

NCBI chr10:84,591,895...84,742,402
Ensembl chr10:84,591,926...84,742,402

G

Rab interacting lysosomal protein-like 1

increases expression

3-dinitrobenzene results in increased expression of RILPL1 mRNA

NCBI chr 5:124,631,143...124,669,684
Ensembl chr 5:124,631,143...124,669,454

G

ripply transcriptional repressor 3

decreases expression

3-dinitrobenzene results in decreased expression of RIPPLY3 mRNA

NCBI chr16:94,129,281...94,137,794
Ensembl chr16:94,129,279...94,137,794

G

Rho family GTPase 1

increases expression

3-dinitrobenzene results in increased expression of RND1 mRNA

NCBI chr15:98,567,086...98,575,342
Ensembl chr15:98,561,302...98,575,342

G

ring finger protein (C3H2C3 type) 6

decreases expression

3-dinitrobenzene results in decreased expression of RNF6 mRNA

NCBI chr 5:146,146,003...146,158,267
Ensembl chr 5:146,146,002...146,158,365

G

ribosomal protein S6 kinase polypeptide 3

increases expression

3-dinitrobenzene results in increased expression of RPS6KA3 mRNA

NCBI chr X:158,038,652...158,151,240
Ensembl chr X:157,993,303...158,151,240

G

related RAS viral (r-ras) oncogene 2

increases expression

3-dinitrobenzene results in increased expression of RRAS2 mRNA

NCBI chr 7:113,646,017...113,717,016
Ensembl chr 7:113,646,017...113,717,016

G

S100 calcium binding protein A10 (calpactin)

increases expression

3-dinitrobenzene results in increased expression of S100A10 mRNA

NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950

G

sarcosine dehydrogenase

increases expression

3-dinitrobenzene results in increased expression of SARDH mRNA

NCBI chr 2:27,078,405...27,138,344
Ensembl chr 2:27,078,405...27,138,349

G

secretogranin II

decreases expression

3-dinitrobenzene results in decreased expression of SCG2 mRNA

NCBI chr 1:79,412,083...79,417,743
Ensembl chr 1:79,412,386...79,417,837

G

syndecan 4

increases expression

3-dinitrobenzene results in increased expression of SDC4 mRNA

NCBI chr 2:164,266,167...164,285,512
Ensembl chr 2:164,266,167...164,285,807

G

succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

increases oxidation

3-dinitrobenzene results in increased oxidation of SDHA protein

NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399

G

secreted frizzled-related protein 4

decreases expression

3-dinitrobenzene results in decreased expression of SFRP4 mRNA

NCBI chr13:19,807,345...19,816,995
Ensembl chr13:19,807,274...19,817,164

G

SH2 domain containing 4A

increases expression

3-dinitrobenzene results in increased expression of SH2D4A mRNA

NCBI chr 8:68,729,180...68,800,356
Ensembl chr 8:68,729,219...68,800,351

G

SH3-domain GRB2-like endophilin B2

increases expression

3-dinitrobenzene results in increased expression of SH3GLB2 mRNA

NCBI chr 2:30,234,789...30,249,380
Ensembl chr 2:30,234,821...30,249,349

G

src homology 2 domain-containing transforming protein C3

decreases expression

3-dinitrobenzene results in decreased expression of SHC3 mRNA

NCBI chr13:51,577,422...51,724,909
Ensembl chr13:51,585,077...51,723,523

G

SHQ1 homolog (S. cerevisiae)

decreases expression

3-dinitrobenzene results in decreased expression of SHQ1 mRNA

NCBI chr 6:100,548,772...100,648,135
Ensembl chr 6:100,545,217...100,648,118

G

SKI family transcriptional corepressor 1

decreases expression

3-dinitrobenzene results in decreased expression of SKOR1 mRNA

NCBI chr 9:63,045,446...63,056,243
Ensembl chr 9:63,045,452...63,056,243

G

solute carrier family 12, member 6

decreases expression

3-dinitrobenzene results in decreased expression of SLC12A6 mRNA

NCBI chr 2:112,096,659...112,193,508
Ensembl chr 2:112,096,170...112,193,508

G

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

affects expression

3-dinitrobenzene affects the expression of SLC13A3 mRNA

NCBI chr 2:165,247,215...165,315,117
Ensembl chr 2:165,246,948...165,315,150

G

solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4

increases expression

3-dinitrobenzene results in increased expression of SLC25A4 mRNA

NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321

G

solute carrier family 34 (sodium phosphate), member 2

decreases expression

3-dinitrobenzene results in decreased expression of SLC34A2 mRNA

NCBI chr 5:53,206,695...53,229,006
Ensembl chr 5:53,195,423...53,229,006

G

solute carrier family 44, member 1

increases expression

3-dinitrobenzene results in increased expression of SLC44A1 mRNA

NCBI chr 4:53,440,387...53,622,478
Ensembl chr 4:53,440,413...53,622,478

G

solute carrier family 45, member 1

increases expression

3-dinitrobenzene results in increased expression of SLC45A1 mRNA

NCBI chr 4:150,713,853...150,736,614
Ensembl chr 4:150,713,029...150,736,631

G

STE20-like kinase

increases expression

3-dinitrobenzene results in increased expression of SLK mRNA

NCBI chr19:47,568,458...47,633,685
Ensembl chr19:47,568,117...47,633,685

G

SMAD family member 7

increases expression

3-dinitrobenzene results in increased expression of SMAD7 mRNA

NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006

G

structural maintenance of chromosomes 1A

increases expression

3-dinitrobenzene results in increased expression of SMC1A mRNA

NCBI chr X:150,799,386...150,844,969
Ensembl chr X:150,799,424...150,845,690

G

SMAD specific E3 ubiquitin protein ligase 1

decreases expression

3-dinitrobenzene results in decreased expression of SMURF1 mRNA

NCBI chr 5:144,813,305...144,902,657
Ensembl chr 5:144,813,305...144,902,657

G

synaptosomal-associated protein 25

increases oxidation

3-dinitrobenzene results in increased oxidation of SNAP25 protein

NCBI chr 2:136,555,359...136,624,348
Ensembl chr 2:136,555,373...136,624,348

G

suppressor of cytokine signaling 2

decreases expression

3-dinitrobenzene results in decreased expression of SOCS2 mRNA

NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042

G

sorbin and SH3 domain containing 1

increases expression

3-dinitrobenzene results in increased expression of SORBS1 mRNA

NCBI chr19:40,280,484...40,502,399
Ensembl chr19:40,283,197...40,502,223

G

sperm acrosome associated 9

decreases expression

3-dinitrobenzene results in decreased expression of SPACA9 protein

NCBI chr 2:28,582,092...28,589,663
Ensembl chr 2:28,582,092...28,589,739

G

speedy/RINGO cell cycle regulator family, member A

decreases expression

3-dinitrobenzene results in decreased expression of SPDYA mRNA

NCBI chr17:71,833,890...71,896,528
Ensembl chr17:71,859,056...71,896,528

G

sperm microtubule inner protein 11

increases expression

3-dinitrobenzene results in increased expression of SPMIP11 mRNA

NCBI chr15:98,468,885...98,487,469
Ensembl chr15:98,468,885...98,487,461

G

spectrin beta, non-erythrocytic 4

decreases expression

3-dinitrobenzene results in decreased expression of SPTBN4 mRNA

NCBI chr 7:27,055,808...27,147,128
Ensembl chr 7:27,055,808...27,147,111

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

increases expression

3-dinitrobenzene results in increased expression of ST3GAL4 mRNA

NCBI chr 9:34,957,872...35,028,160
Ensembl chr 9:34,957,872...35,030,564

G

STAM binding protein

decreases expression

3-dinitrobenzene results in decreased expression of STAMBP mRNA

NCBI chr 6:83,520,188...83,552,781
Ensembl chr 6:83,520,193...83,549,711

G

steroidogenic acute regulatory protein

decreases expression

3-dinitrobenzene results in decreased expression of STAR mRNA

NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010

G

signal transducer and activator of transcription 3

increases expression

3-dinitrobenzene results in increased expression of STAT3 mRNA

PMID:21983209 PMID:22841810

NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366

G

syntaxin 11

increases expression

3-dinitrobenzene results in increased expression of STX11 mRNA

NCBI chr10:12,813,961...12,840,242
Ensembl chr10:12,813,953...12,840,042

G

syntaxin 17

affects expression

3-dinitrobenzene affects the expression of STX17 mRNA

NCBI chr 4:48,124,912...48,186,507
Ensembl chr 4:48,124,915...48,186,507

G

syntaxin binding protein 1

increases oxidation

3-dinitrobenzene results in increased oxidation of STXBP1 protein

NCBI chr 2:32,677,619...32,737,249
Ensembl chr 2:32,677,614...32,737,257

G

sulfatase modifying factor 2

decreases expression

3-dinitrobenzene results in decreased expression of SUMF2 mRNA

NCBI chr 5:129,875,807...129,892,275
Ensembl chr 5:129,875,827...129,892,891

G

TATA-box binding protein associated factor 1

increases expression

3-dinitrobenzene results in increased expression of TAF1 mRNA

NCBI chr X:100,576,335...100,644,635
Ensembl chr X:100,576,279...100,644,640

G

TBC1 domain family, member 5

decreases expression

3-dinitrobenzene results in decreased expression of TBC1D5 mRNA

NCBI chr17:51,040,155...51,488,228
Ensembl chr17:51,040,152...51,486,380

G

TBCC domain containing 1

decreases expression

3-dinitrobenzene results in decreased expression of TBCCD1 mRNA

NCBI chr16:22,631,964...22,676,441
Ensembl chr16:22,631,964...22,676,419

G

tudor domain containing 1

decreases expression

3-dinitrobenzene results in decreased expression of TDRD1 mRNA

NCBI chr19:56,814,603...56,858,444
Ensembl chr19:56,814,641...56,858,444

G

TEK receptor tyrosine kinase

increases expression

3-dinitrobenzene results in increased expression of TEK mRNA

NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213

G

telomere maintenance 2

decreases expression

3-dinitrobenzene results in decreased expression of TELO2 mRNA

NCBI chr17:25,318,543...25,334,951
Ensembl chr17:25,318,544...25,334,941

G

transforming growth factor alpha

decreases expression

3-dinitrobenzene results in decreased expression of TGFA mRNA

PMID:21983209 PMID:22841810

NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701

G

THO complex 7

decreases expression

3-dinitrobenzene results in decreased expression of THOC7 mRNA

NCBI chr14:8,507,911...8,520,751
Ensembl chr14:8,507,911...8,520,751

G

T cell lymphoma invasion and metastasis 1

increases expression

3-dinitrobenzene results in increased expression of TIAM1 mRNA

NCBI chr16:89,583,999...89,942,488
Ensembl chr16:89,583,999...89,940,657

G

tight junction protein 2

increases expression

3-dinitrobenzene results in increased expression of TJP2 mRNA

NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394

G

transketolase

increases expression

3-dinitrobenzene results in increased expression of TKT mRNA

NCBI chr14:30,271,088...30,296,681
Ensembl chr14:30,270,316...30,296,677

G

transmembrane p24 trafficking protein 4

decreases expression

3-dinitrobenzene results in decreased expression of TMED4 mRNA

NCBI chr11:6,220,714...6,224,837
Ensembl chr11:6,220,369...6,224,870

G

transmembrane protein 230

decreases expression

3-dinitrobenzene results in decreased expression of TMEM230 mRNA

NCBI chr 2:132,081,412...132,089,708
Ensembl chr 2:132,081,412...132,089,727

G

transmembrane protein 38B

decreases expression

3-dinitrobenzene results in decreased expression of TMEM38B mRNA

NCBI chr 4:53,825,988...53,862,019
Ensembl chr 4:53,826,045...53,862,019

G

transmembrane protein 67

decreases expression

3-dinitrobenzene results in decreased expression of TMEM67 mRNA

NCBI chr 4:12,039,355...12,090,020
Ensembl chr 4:12,039,363...12,090,020

G

tumor necrosis factor receptor superfamily, member 12a

increases expression

3-dinitrobenzene results in increased expression of TNFRSF12A mRNA

PMID:22841810 PMID:24140754

NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442

G

tumor necrosis factor receptor superfamily, member 1a

increases expression

3-dinitrobenzene results in increased expression of TNFRSF1A mRNA

NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447

G

tumor protein D52-like 1

increases expression

3-dinitrobenzene results in increased expression of TPD52L1 mRNA

NCBI chr10:31,208,369...31,321,989
Ensembl chr10:31,208,372...31,321,954

G

triosephosphate isomerase 1

decreases expression

3-dinitrobenzene results in decreased expression of TPI1 protein

NCBI chr 6:124,787,549...124,791,121
Ensembl chr 6:124,787,549...124,791,259

G

tropomyosin 1, alpha

increases expression

3-dinitrobenzene results in increased expression of TPM1 mRNA

NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688

G

tripartite motif-containing 14

decreases expression
affects expression

3-dinitrobenzene results in decreased expression of TRIM14 mRNA
3-dinitrobenzene affects the expression of TRIM14 mRNA

PMID:21983209 PMID:24140754

NCBI chr 4:46,505,072...46,536,148
Ensembl chr 4:46,493,781...46,536,141

G

tRNA methyltransferase 12

decreases expression

3-dinitrobenzene results in decreased expression of TRMT12 mRNA

PMID:21983209 PMID:24140754

NCBI chr15:58,744,498...58,748,630
Ensembl chr15:58,744,523...58,748,976

G

tubulin, beta 2A class IIA

increases oxidation

3-dinitrobenzene results in increased oxidation of TUBB2A protein

NCBI chr13:34,258,261...34,261,991
Ensembl chr13:34,258,257...34,261,990

G

ubiquitin-like modifier activating enzyme 1

affects expression
decreases expression

3-dinitrobenzene affects the expression of UBA1 mRNA
3-dinitrobenzene results in decreased expression of UBA1 mRNA

PMID:16988215 PMID:24140754

NCBI chr X:20,524,660...20,549,420
Ensembl chr X:20,524,565...20,549,418

G

ubiquitin associated and SH3 domain containing, B

increases expression

3-dinitrobenzene results in increased expression of UBASH3B mRNA

NCBI chr 9:40,922,056...41,069,358
Ensembl chr 9:40,922,394...41,072,993

G

ubiquitin D

decreases expression

3-dinitrobenzene results in decreased expression of UBD mRNA

NCBI chr17:37,504,783...37,506,992
Ensembl chr17:37,504,783...37,506,986

G

ubiquitin-conjugating enzyme E2A

decreases expression

3-dinitrobenzene results in decreased expression of UBE2A mRNA

NCBI chr X:36,137,948...36,147,875
Ensembl chr X:36,064,828...36,147,875

G

ubiquitin-conjugating enzyme E2B

increases expression

3-dinitrobenzene results in increased expression of UBE2B mRNA

NCBI chr11:51,875,965...51,894,972
Ensembl chr11:51,876,324...51,891,589

G

ubiquitin-conjugating enzyme E2C

decreases expression

3-dinitrobenzene results in decreased expression of UBE2C mRNA

NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742

G

ubiquitin-conjugating enzyme E2D 1

decreases expression

3-dinitrobenzene results in decreased expression of UBE2D1 mRNA

NCBI chr10:71,090,810...71,121,048
Ensembl chr10:71,090,810...71,121,092

G

ubiquitin-conjugating enzyme E2D 2A

increases expression

3-dinitrobenzene results in increased expression of UBE2D2 mRNA

NCBI chr18:35,904,612...35,940,225
Ensembl chr18:35,904,611...35,942,547

G

ubiquitin-conjugating enzyme E2D 3

affects expression

3-dinitrobenzene affects the expression of UBE2D3 mRNA

NCBI chr 3:135,143,993...135,173,975
Ensembl chr 3:135,143,910...135,173,959

G

ubiquitin-conjugating enzyme E2E 3

increases expression

3-dinitrobenzene results in increased expression of UBE2E3 mRNA

NCBI chr 2:78,698,696...78,759,132
Ensembl chr 2:78,698,468...78,751,637

G

ubiquitin-conjugating enzyme E2G 1

increases expression

3-dinitrobenzene results in increased expression of UBE2G1 mRNA

NCBI chr11:72,498,087...72,577,307
Ensembl chr11:72,498,109...72,577,307

G

ubiquitin-conjugating enzyme E2M

decreases expression

3-dinitrobenzene results in decreased expression of UBE2M mRNA

NCBI chr 7:12,769,047...12,772,202
Ensembl chr 7:12,769,047...12,772,202

G

ubiquitin-conjugating enzyme E2N

decreases expression

3-dinitrobenzene results in decreased expression of UBE2N mRNA

NCBI chr10:95,351,024...95,381,520
Ensembl chr10:95,351,007...95,381,519

G

ubiquitination factor E4A

increases expression

3-dinitrobenzene results in increased expression of UBE4A mRNA

NCBI chr 9:44,834,425...44,877,021
Ensembl chr 9:44,834,425...44,876,898

G

ubiquitin carboxy-terminal hydrolase L1

affects expression

3-dinitrobenzene affects the expression of UCHL1 mRNA

NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577

G

UFM1 specific ligase 1

decreases expression

3-dinitrobenzene results in decreased expression of UFL1 mRNA

NCBI chr 4:25,247,149...25,281,821
Ensembl chr 4:25,248,600...25,281,821

G

upstream transcription factor 1

increases expression

3-dinitrobenzene results in increased expression of USF1 mRNA

NCBI chr 1:171,238,881...171,246,327
Ensembl chr 1:171,238,881...171,246,710

G

ubiquitin specific peptidase 28

increases expression

3-dinitrobenzene results in increased expression of USP28 mRNA

NCBI chr 9:48,896,577...48,953,817
Ensembl chr 9:48,896,675...48,953,817

G

ubiquitin specific peptidase 32

increases expression

3-dinitrobenzene results in increased expression of USP32 mRNA

NCBI chr11:84,875,263...85,031,107
Ensembl chr11:84,875,268...85,030,987

G

ubiquitin specific peptidase 35

decreases expression

3-dinitrobenzene results in decreased expression of USP35 mRNA

NCBI chr 7:96,958,610...96,981,502
Ensembl chr 7:96,958,587...96,981,227

G

ubiquitin specific peptidase 40

increases expression

3-dinitrobenzene results in increased expression of USP40 mRNA

NCBI chr 1:87,872,841...87,936,308
Ensembl chr 1:87,872,841...87,936,273

G

ubiquitin specific peptidase 47

increases expression

3-dinitrobenzene results in increased expression of USP47 mRNA

NCBI chr 7:111,622,692...111,710,591
Ensembl chr 7:111,622,711...111,710,868

G

ubiquitin specific peptidase 48

increases expression

3-dinitrobenzene results in increased expression of USP48 mRNA

NCBI chr 4:137,321,079...137,385,842
Ensembl chr 4:137,321,066...137,385,848

G

ubiquitin specific peptidase 54

increases expression

3-dinitrobenzene results in increased expression of USP54 mRNA

NCBI chr14:20,598,980...20,694,559
Ensembl chr14:20,598,980...20,691,131

G

vinculin

increases expression

3-dinitrobenzene results in increased expression of VCL mRNA

NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744

G

vimentin

increases metabolic processing

3-dinitrobenzene results in increased metabolism of VIM protein

NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637

G

VPS26 retromer complex component A

decreases expression

3-dinitrobenzene results in decreased expression of VPS26A mRNA

NCBI chr10:62,290,622...62,322,584
Ensembl chr10:62,291,014...62,322,584

G

WD repeat domain 3

increases expression

3-dinitrobenzene results in increased expression of WDR3 mRNA

NCBI chr 3:100,045,496...100,069,723
Ensembl chr 3:100,045,496...100,069,723

G

WNK lysine deficient protein kinase 4

increases expression

3-dinitrobenzene results in increased expression of WNK4 mRNA

NCBI chr11:101,151,363...101,168,235
Ensembl chr11:101,151,393...101,168,235

G

wingless-type MMTV integration site family, member 2

increases expression

3-dinitrobenzene results in increased expression of WNT2 mRNA

NCBI chr 6:17,988,939...18,032,771
Ensembl chr 6:17,988,939...18,030,584

G

wingless-type MMTV integration site family, member 4

increases expression

3-dinitrobenzene results in increased expression of WNT4 mRNA

NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037

G

wingless-type MMTV integration site family, member 5B

increases expression

3-dinitrobenzene results in increased expression of WNT5B mRNA

NCBI chr 6:119,409,493...119,521,847
Ensembl chr 6:119,409,492...119,521,308

G

xin actin-binding repeat containing 1

affects expression

3-dinitrobenzene affects the expression of XIRP1 mRNA

NCBI chr 9:119,842,821...119,852,660
Ensembl chr 9:119,842,821...119,852,664

G

X-ray repair complementing defective repair in Chinese hamster cells 2

decreases expression

3-dinitrobenzene results in decreased expression of XRCC2 mRNA

NCBI chr 5:25,894,812...25,910,795
Ensembl chr 5:25,894,810...25,910,823

G

zinc finger, CCHC domain containing 12

increases expression

3-dinitrobenzene results in increased expression of ZCCHC12 mRNA

NCBI chr X:35,459,553...35,462,817
Ensembl chr X:35,459,557...35,462,811

G

zinc finger protein 446

decreases expression

3-dinitrobenzene results in decreased expression of ZFP446 mRNA

NCBI chr 7:12,711,726...12,718,323
Ensembl chr 7:12,711,775...12,719,641

G

zinc finger protein 672

decreases expression

3-dinitrobenzene results in decreased expression of ZFP672 protein

NCBI chr11:58,205,940...58,221,197
Ensembl chr11:58,205,940...58,221,165

G

zinc fingers and homeoboxes 2

increases expression

3-dinitrobenzene results in increased expression of ZHX2 mRNA

NCBI chr15:57,558,063...57,703,228
Ensembl chr15:57,558,061...57,703,228

G

zinc and ring finger 2

decreases expression

3-dinitrobenzene results in decreased expression of ZNRF2 mRNA

NCBI chr 6:54,793,901...54,867,209
Ensembl chr 6:54,793,901...54,870,485

G

zyxin

increases expression

3-dinitrobenzene results in increased expression of ZYX mRNA

NCBI chr 6:42,326,507...42,337,158
Ensembl chr 6:42,326,564...42,337,147

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	22182
role	22167
biological role	22166
aetiopathogenetic role	21269
neurotoxin	18809
1,3-dinitrobenzene	391
Path 2
Term	Annotations
CHEBI ontology	22182
subatomic particle	22174
composite particle	22174
hadron	22174
baryon	22174
nucleon	22174
atomic nucleus	22174
atom	22174
main group element atom	22108
p-block element atom	22108
carbon group element atom	21909
carbon atom	21835
organic molecular entity	21835
organic molecule	21652
organic cyclic compound	21261
carbocyclic compound	19695
benzenoid aromatic compound	18832
benzenes	18634
nitrobenzenes	1791
dinitrobenzene	392
1,3-dinitrobenzene	391

paths to the root