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Gene: Ppp1ca (protein phosphatase 1 catalytic subunit alpha) Mus musculus
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Symbol: Ppp1ca
Name: protein phosphatase 1 catalytic subunit alpha
Description: Exhibits protein serine/threonine phosphatase activity. Involved in several processes, including circadian regulation of gene expression; entrainment of circadian clock by photoperiod; and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Localizes to the cytoplasm and nucleoplasm. Predicted to colocalize with the nuclear chromosome, telomeric region. Is expressed in several structures, including esophagus; eye; and respiratory system. Orthologous to human PPP1CA (protein phosphatase 1 catalytic subunit alpha); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; Bone morphogenetic proteins signaling pathway; dopamine signaling pathway; INTERACTS WITH (S)-colchicine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dism2; PP-1A; Ppp1c; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38194,192,174 - 4,195,419 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37194,192,174 - 4,195,419 (+)NCBIGRCm37mm9NCBIm37
MGSCv36194,192,174 - 4,195,419 (+)NCBImm8
Celera194,063,314 - 4,066,560 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Ppp1ca
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11132
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.