Vcl (vinculin) - Rat Genome Database

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Gene: Vcl (vinculin) Mus musculus
Analyze
Symbol: Vcl
Name: vinculin
RGD ID: 1322561
MGI Page MGI
Description: Predicted to have alpha-catenin binding activity; dystroglycan binding activity; and enzyme binding activity. Involved in cell adhesion; plasma membrane bounded cell projection organization; and regulation of cell migration. Localizes to several cellular components, including costamere; fascia adherens; and focal adhesion. Predicted to colocalize with actin filament and stress fiber. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and yolk sac. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1W; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 15. Orthologous to human VCL (vinculin); PARTICIPATES IN E-cadherin signaling pathway; vascular endothelial growth factor signaling pathway; Entamoebiasis pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 1,8-cineole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9430097D22; AA571387; AI462105; AW545629; metavinculin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391420,979,436 - 21,083,744 (+)NCBIGRCm39mm39
GRCm39 Ensembl1420,979,466 - 21,083,744 (+)Ensembl
GRCm381420,929,383 - 21,033,676 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1420,929,398 - 21,033,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv371421,748,655 - 21,852,895 (+)NCBIGRCm37mm9NCBIm37
MGSCv361419,717,985 - 19,822,225 (+)NCBImm8
Celera1417,309,615 - 17,412,913 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1,8-cineole  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,6-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
2-methoxyethanol  (ISO)
2-methylcholine  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-vinylcyclohexene dioxide  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
aniline  (ISO)
antirheumatic drug  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
chloroprene  (ISO)
chromium(6+)  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP,ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (EXP,ISO)
diclofenac  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenamidone  (EXP)
flutamide  (ISO)
folic acid  (EXP)
fructose  (ISO)
fumonisin B1  (EXP)
genistein  (EXP,ISO)
glucose  (EXP)
glycerol 2-phosphate  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
griseofulvin  (EXP)
hydrogen peroxide  (ISO)
hydrogen sulfide  (EXP)
hydroxychloroquine  (ISO)
imidacloprid  (ISO)
indometacin  (ISO)
leflunomide  (ISO)
methotrexate  (ISO)
microcystin RR  (ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
naphthalene  (EXP)
nickel atom  (EXP)
Nonylphenol  (EXP)
ozone  (ISO)
paclitaxel  (EXP)
paracetamol  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP,ISO)
resveratrol  (EXP,ISO)
rimonabant  (EXP)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
sodium sulfide (anhydrous)  (EXP)
Soman  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
trichostatin A  (ISO)
troglitazone  (EXP)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (EXP)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cardiac muscle relaxation  (IAGP)
abnormal cardiovascular system morphology  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal cell adhesion  (IAGP)
abnormal cranial nerve morphology  (IAGP)
abnormal ectoderm development  (IAGP)
abnormal embryonic neuroepithelial layer differentiation  (IAGP)
abnormal embryonic tissue physiology  (IAGP)
abnormal foregut morphology  (IAGP)
abnormal forelimb bud morphology  (IAGP)
abnormal head development  (IAGP)
abnormal head mesenchyme morphology  (IAGP)
abnormal head shape  (IAGP)
abnormal heart development  (IAGP)
abnormal heart electrocardiography waveform feature  (IAGP)
abnormal heart position or orientation  (IAGP)
abnormal impulse conducting system conduction  (IAGP)
abnormal intercalated disk morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal neural fold formation  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal pericardial cavity morphology  (IAGP)
abnormal spinal nerve morphology  (IAGP)
absent atrioventricular cushions  (IAGP)
absent brain ventricles  (IAGP)
absent heart valves  (IAGP)
cardiac fibrosis  (IAGP)
cardiac hypertrophy  (IAGP)
congestive heart failure  (IAGP)
decreased brain size  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased embryo size  (IAGP)
decreased embryonic neuroepithelium thickness  (IAGP)
decreased myocardial fiber number  (IAGP)
decreased somite size  (IAGP)
decreased ventricle muscle contractility  (IAGP)
delayed heart development  (IAGP)
dilated cardiomyopathy  (IAGP)
dilated heart left ventricle  (IAGP)
dilated vasculature  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
exencephaly  (IAGP)
failure of somite differentiation  (IAGP)
heart block  (IAGP)
incomplete rostral neuropore closure  (IAGP)
increased apoptosis  (IAGP)
increased embryonic neuroepithelium apoptosis  (IAGP)
increased fibroblast proliferation  (IAGP)
increased heart weight  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
irregular heartbeat  (IAGP)
premature death  (IAGP)
prolonged QRS complex duration  (IAGP)
short rostral-caudal axis  (IAGP)
small brain ventricles  (IAGP)
small dorsal root ganglion  (IAGP)
small forelimb buds  (IAGP)
small heart  (IAGP)
thin myocardium  (IAGP)
ventricular tachycardia  (IAGP)
wavy neural tube  (IAGP)
References

Additional References at PubMed
PMID:2116004   PMID:2127699   PMID:7568093   PMID:7646816   PMID:8833241   PMID:8861907   PMID:9280281   PMID:9415431   PMID:9486805   PMID:10085297   PMID:10349636   PMID:10615402  
PMID:10833443   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11470398   PMID:11724819   PMID:11732910   PMID:11785963   PMID:11807098   PMID:11991656   PMID:12068957  
PMID:12112462   PMID:12133899   PMID:12473693   PMID:12477932   PMID:12520002   PMID:12651156   PMID:14657280   PMID:15031111   PMID:15102471   PMID:15128702   PMID:15138291   PMID:15148305  
PMID:15159399   PMID:15229287   PMID:15328010   PMID:15331426   PMID:15350277   PMID:15465019   PMID:15489334   PMID:15579911   PMID:15679099   PMID:15883197   PMID:15893749   PMID:15967814  
PMID:16000373   PMID:16126177   PMID:16141072   PMID:16141073   PMID:16374517   PMID:16407299   PMID:16407302   PMID:16481394   PMID:16584805   PMID:16973151   PMID:17015619   PMID:17112388  
PMID:17785437   PMID:17890382   PMID:17893324   PMID:17925492   PMID:18056416   PMID:18061163   PMID:18256189   PMID:18448675   PMID:18685100   PMID:19004856   PMID:19075109   PMID:19126201  
PMID:19126403   PMID:19168634   PMID:19449303   PMID:19538749   PMID:19542491   PMID:19580787   PMID:19652092   PMID:19666558   PMID:19667078   PMID:19793892   PMID:19951918   PMID:20006947  
PMID:20181946   PMID:20205236   PMID:20308429   PMID:20610383   PMID:20644727   PMID:20663867   PMID:20670372   PMID:20678470   PMID:20716775   PMID:20737513   PMID:20841379   PMID:20886612  
PMID:21048959   PMID:21107430   PMID:21224394   PMID:21267068   PMID:21270129   PMID:21295550   PMID:21401944   PMID:21403399   PMID:21536590   PMID:21677750   PMID:21841197   PMID:21924239  
PMID:22174917   PMID:22349694   PMID:22405651   PMID:22416133   PMID:22560610   PMID:22629443   PMID:22673621   PMID:22705452   PMID:22791713   PMID:22843502   PMID:22925892   PMID:22956851  
PMID:22984613   PMID:23055941   PMID:23152823   PMID:23175628   PMID:23236519   PMID:23260139   PMID:23266827   PMID:23266828   PMID:23375895   PMID:23389036   PMID:23542691   PMID:23561539  
PMID:23589308   PMID:23595642   PMID:23637629   PMID:23658024   PMID:23716647   PMID:23744273   PMID:23836933   PMID:23872053   PMID:23974298   PMID:24036928   PMID:24056078   PMID:24413171  
PMID:24590285   PMID:24614889   PMID:24623780   PMID:24675074   PMID:24751539   PMID:24996180   PMID:25020278   PMID:25077739   PMID:25115937   PMID:25139745   PMID:25179606   PMID:25193699  
PMID:25217619   PMID:25358683   PMID:25546391   PMID:25737280   PMID:25937343   PMID:26195589   PMID:26240176   PMID:26359501   PMID:26437238   PMID:26465331   PMID:26634421   PMID:26876175  
PMID:26989131   PMID:27171814   PMID:27775552   PMID:27880909   PMID:28089450   PMID:28115535   PMID:28153048   PMID:28199840   PMID:28218286   PMID:28378742   PMID:28388663   PMID:28485208  
PMID:28663132   PMID:28808245   PMID:28826662   PMID:29046336   PMID:29093447   PMID:29162887   PMID:29241625   PMID:29411501   PMID:29642037   PMID:30169110   PMID:30333137   PMID:30335684  
PMID:30578314   PMID:30947518   PMID:31180501   PMID:31201155   PMID:31246175   PMID:31399484   PMID:31483697   PMID:31483833   PMID:31582725   PMID:31659275   PMID:31680852   PMID:31804547  
PMID:31833472   PMID:31896583   PMID:32165492   PMID:32238906   PMID:32325033   PMID:32434143   PMID:32541003   PMID:32581705   PMID:33335089   PMID:33725480  


Genomics

Comparative Map Data
Vcl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391420,979,436 - 21,083,744 (+)NCBIGRCm39mm39
GRCm39 Ensembl1420,979,466 - 21,083,744 (+)Ensembl
GRCm381420,929,383 - 21,033,676 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1420,929,398 - 21,033,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv371421,748,655 - 21,852,895 (+)NCBIGRCm37mm9NCBIm37
MGSCv361419,717,985 - 19,822,225 (+)NCBImm8
Celera1417,309,615 - 17,412,913 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.53NCBI
VCL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1073,995,193 - 74,121,363 (+)EnsemblGRCh38hg38GRCh38
GRCh381073,998,116 - 74,121,363 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371075,757,874 - 75,881,121 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361075,427,878 - 75,549,924 (+)NCBINCBI36hg18NCBI36
Build 341075,427,877 - 75,549,918NCBI
Celera1069,043,066 - 69,165,189 (+)NCBI
Cytogenetic Map10q22.2NCBI
HuRef1069,753,196 - 69,875,221 (+)NCBIHuRef
CHM1_11076,039,663 - 76,161,889 (+)NCBICHM1_1
Vcl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2153,265,776 - 3,355,586 (-)NCBI
Rnor_6.0 Ensembl153,455,211 - 3,544,702 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0153,455,211 - 3,544,738 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0153,433,521 - 3,522,441 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,478,214 - 3,576,911 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1153,480,194 - 3,654,123 (-)NCBI
Celera151,235,777 - 1,325,408 (+)NCBICelera
Cytogenetic Map15p16NCBI
Vcl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543717,813,007 - 17,920,253 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543717,812,998 - 17,920,253 (-)NCBIChiLan1.0ChiLan1.0
VCL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11073,191,384 - 73,311,301 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1073,191,375 - 73,311,296 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01070,521,259 - 70,641,917 (+)NCBIMhudiblu_PPA_v0panPan3
VCL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1424,404,279 - 24,518,977 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl424,404,319 - 24,518,633 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha424,541,842 - 24,656,546 (+)NCBI
ROS_Cfam_1.0424,685,066 - 24,802,488 (+)NCBI
UMICH_Zoey_3.1424,581,947 - 24,697,844 (+)NCBI
UNSW_CanFamBas_1.0424,782,214 - 24,897,783 (+)NCBI
UU_Cfam_GSD_1.0425,137,362 - 25,252,305 (+)NCBI
Vcl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721356,558,734 - 56,670,307 (-)NCBI
SpeTri2.0NW_0049365215,051,077 - 5,163,036 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VCL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1476,700,168 - 76,811,875 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11476,700,143 - 76,811,875 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21482,826,487 - 82,938,103 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap14q2.5-q2.9NCBI
VCL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1957,253,219 - 57,375,947 (-)NCBI
ChlSab1.1 Ensembl957,255,166 - 57,376,028 (-)Ensembl
Vero_WHO_p1.0NW_02366604817,825,838 - 17,950,842 (-)NCBI
Vcl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247547,484,759 - 7,590,108 (+)NCBI

Position Markers
AW545629  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381421,033,060 - 21,033,200UniSTSGRCm38
MGSCv371421,852,282 - 21,852,422UniSTSGRCm37
Celera1417,412,300 - 17,412,440UniSTS
Cytogenetic Map14A3UniSTS
cM Map142.5UniSTS
Whitehead/MRC_RH14172.12UniSTS
D14Mit50  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381421,012,382 - 21,012,571UniSTSGRCm38
MGSCv371421,831,604 - 21,831,793UniSTSGRCm37
Celera1417,391,602 - 17,391,781UniSTS
Cytogenetic Map14A3UniSTS
cM Map144.0UniSTS
Whitehead Genetic149.8UniSTS
Whitehead_YAC14 UniSTS
AI462105  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381421,033,288 - 21,033,582UniSTSGRCm38
MGSCv371421,852,510 - 21,852,804UniSTSGRCm37
Celera1417,412,528 - 17,412,822UniSTS
Cytogenetic Map14A3UniSTS
cM Map142.5UniSTS
cM Map142.5UniSTS
Whitehead/MRC_RH1433.36UniSTS
RH124252  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381421,032,421 - 21,032,510UniSTSGRCm38
MGSCv371421,851,643 - 21,851,732UniSTSGRCm37
Celera1417,411,661 - 17,411,750UniSTS
Cytogenetic Map14A3UniSTS
cM Map142.5UniSTS
D15M14Mit50  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381421,012,410 - 21,012,552UniSTSGRCm38
MGSCv371421,831,632 - 21,831,774UniSTSGRCm37
Celera1417,391,630 - 17,391,762UniSTS
Cytogenetic Map14A3UniSTS
cM Map142.5UniSTS
VCL  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381421,029,179 - 21,029,379UniSTSGRCm38
MGSCv371421,848,401 - 21,848,601UniSTSGRCm37
Celera1417,408,419 - 17,408,619UniSTS
Cytogenetic Map14A3UniSTS
cM Map142.5UniSTS
cM Map142.5UniSTS
cM Map142.5UniSTS
BARC0060  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381421,020,693 - 21,022,118UniSTSGRCm38
MGSCv371421,839,915 - 21,841,340UniSTSGRCm37
Celera1417,399,915 - 17,401,340UniSTS
Cytogenetic Map14A3UniSTS
cM Map142.5UniSTS
Vcl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14A3UniSTS
cM Map142.5UniSTS
Vcl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14A3UniSTS
cM Map142.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532711Sluc40_msusceptibility to lung cancer 40 (mouse)14129089969Mouse
10412071Ssen3_msuseptibility to Sendai virus 3 (mouse)Not determined14129481959Mouse
13824988Phsq1_mpercent hyperactivated sperm QTL 1 (mouse)14300000021000000Mouse
1301991Wta3_mweight adult 3 (mouse)Not determined14383740537837582Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined509340539093528Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)14870000046500000Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)14870000047000000Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141249091446491050Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined1254601848527625Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141543865949438808Mouse
4141265Appd2_mAPP associated premature death 2 (mouse)Not determined141652371130392905Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141910564753105769Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142101238271648361Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:694
Count of miRNA genes:442
Interacting mature miRNAs:504
Transcripts:ENSMUST00000022369
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000022369   ⟹   ENSMUSP00000022369
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1420,929,398 - 21,033,676 (+)Ensembl
RefSeq Acc Id: ENSMUST00000224380   ⟹   ENSMUSP00000153447
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1421,022,003 - 21,027,217 (+)Ensembl
RefSeq Acc Id: ENSMUST00000226113
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1420,929,398 - 20,998,781 (+)Ensembl
RefSeq Acc Id: NM_009502   ⟹   NP_033528
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391420,979,466 - 21,083,744 (+)NCBI
GRCm381420,929,398 - 21,033,676 (+)NCBI
MGSCv371421,748,655 - 21,852,895 (+)RGD
Celera1417,309,615 - 17,412,913 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006518922   ⟹   XP_006518985
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391420,979,436 - 21,083,741 (+)NCBI
GRCm381420,929,383 - 21,033,676 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033528   ⟸   NM_009502
- UniProtKB: Q64727 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006518985   ⟸   XM_006518922
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000153447   ⟸   ENSMUST00000224380
RefSeq Acc Id: ENSMUSP00000022369   ⟸   ENSMUST00000022369

Promoters
RGD ID:8681632
Promoter ID:EPDNEW_M18846
Type:initiation region
Name:Vcl_1
Description:Mus musculus vinculin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381420,929,425 - 20,929,485EPDNEW
RGD ID:6825518
Promoter ID:MM_KWN:15821
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_009502,   UC007SKY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361421,748,136 - 21,749,152 (+)MPROMDB
RGD ID:6825519
Promoter ID:MM_KWN:15823
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000090432
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361421,847,761 - 21,848,862 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98927 AgrOrtholog
Ensembl Genes ENSMUSG00000021823 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000022369 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000153447 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022369 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000224380 UniProtKB/TrEMBL
InterPro Alpha-catenin/vinculin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vinculin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vinculin/catenin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vinculin_CS UniProtKB/Swiss-Prot
KEGG Report mmu:22330 UniProtKB/Swiss-Prot
MGD MGI:98927 ENTREZGENE
NCBI Gene 22330 ENTREZGENE
PANTHER PTHR46180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Vinculin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Vcl PhenoGen
PROSITE VINCULIN_1 UniProtKB/Swiss-Prot
  VINCULIN_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286YDJ4_MOUSE UniProtKB/TrEMBL
  Q64727 ENTREZGENE
  Q9ESQ3_MOUSE UniProtKB/TrEMBL
  VINC_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8BP32 UniProtKB/Swiss-Prot
  Q8BS46 UniProtKB/Swiss-Prot
  Q922C5 UniProtKB/Swiss-Prot
  Q922D9 UniProtKB/Swiss-Prot