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Gene: Ehd1 (EH-domain containing 1) Mus musculus
Symbol: Ehd1
Name: EH-domain containing 1
Description: Predicted to have Rab GTPase binding activity and identical protein binding activity. Involved in several processes, including cholesterol homeostasis; low-density lipoprotein particle clearance; and positive regulation of cholesterol storage. Localizes to several cellular components, including the cytoplasmic vesicle; lipid droplet; and platelet dense tubular network membrane. Is expressed in several structures, including branchial arch; genitourinary system; limb bud; musculoskeletal system; and retina layer. Orthologous to human EHD1 (EH domain containing 1); PARTICIPATES IN retromer-mediated pathway; endocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA409636; EH domain-containing protein 1; mPAST1; PAST homolog 1; Past1; RME-1
Homo sapiens (human) : EHD1 (EH domain containing 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ehd1 (EH-domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ehd1 (EH domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EHD1 (EH domain containing 1)
Canis lupus familiaris (dog) : EHD1 (EH domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ehd1 (EH domain containing 1)
Sus scrofa (pig) : EHD1 (EH domain containing 1)
Chlorocebus sabaeus (green monkey) : EHD1 (EH domain containing 1)
Heterocephalus glaber (naked mole-rat) : Ehd1 (EH domain containing 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl196,276,725 - 6,300,096 (+)Ensembl
GRCm38196,276,896 - 6,300,096 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,276,896 - 6,300,096 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,276,896 - 6,300,096 (+)NCBImm8
Celera196,149,194 - 6,172,784 (+)NCBICelera
Cytogenetic Map19 ANCBI
cM Map194.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ehd1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1619277
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.