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Gene: Gjb6 (gap junction protein, beta 6) Mus musculus
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Symbol: Gjb6
Name: gap junction protein, beta 6
Description: Predicted to have cytoskeletal protein binding activity and gap junction channel activity involved in cell communication by electrical coupling. Involved in ear morphogenesis and sensory perception of sound. Localizes to the gap junction. Used to study Clouston syndrome and autosomal recessive nonsyndromic deafness 1A. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 3B; autosomal recessive nonsyndromic deafness 1A; autosomal recessive nonsyndromic deafness 1B; and ectodermal dysplasia. Is expressed in bladder; urinary system; and urothelium of bladder. Orthologous to human GJB6 (gap junction protein beta 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; Benzo[k]fluoranthene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA958971; connexin 30; connexin-30; Cx30; D14Bwg0506e; gap junction beta-6 protein; gap junction membrane channel protein beta 6
Orthologs:
Homo sapiens (human) : GJB6 (gap junction protein beta 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gjb6 (gap junction protein, beta 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gjb6 (gap junction protein beta 6)
Pan paniscus (bonobo/pygmy chimpanzee) : GJB6 (gap junction protein beta 6)
Canis lupus familiaris (dog) : GJB6 (gap junction protein beta 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gjb6 (gap junction protein beta 6)
Sus scrofa (pig) : GJB6 (gap junction protein beta 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381457,123,301 - 57,133,611 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371457,742,140 - 57,752,414 (-)NCBIGRCm37mm9NCBIm37
MGSCv361456,077,413 - 56,087,687 (-)NCBImm8
Celera1454,913,861 - 54,924,166 (-)NCBICelera
Cytogenetic Map14 C3NCBI
cM Map1430.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gjb6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551751
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.