Bcl11a (BCL11 transcription factor A) - Rat Genome Database

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Gene: Bcl11a (BCL11 transcription factor A) Mus musculus
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Symbol: Bcl11a
Name: BCL11 transcription factor A
RGD ID: 1320528
MGI Page MGI
Description: Enables transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II and protein sumoylation. Acts upstream of or within B cell differentiation; T cell differentiation; and negative regulation of gene expression. Located in nuclear body. Part of SWI/SNF complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BCL11 transcription factor A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2810047E18Rik; B cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell lymphoma/leukemia 11A; BCL-11A; COUP-TF interacting protein 1; COUP-TF-interacting protein 1; CTI; Ctip1; D930021L15Rik; ecotropic viral integration site 9 protein; Ev; Evi; EVI-9; Evi9; Evi9a; Evi9b; Evi9c; mKIAA1809; myeloid leukemia
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391124,026,498 - 24,123,558 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1124,028,056 - 24,124,123 (+)EnsemblGRCm39 Ensembl
GRCm381124,076,564 - 24,173,558 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1124,078,056 - 24,174,123 (+)EnsemblGRCm38mm10GRCm38
MGSCv371123,978,056 - 24,073,558 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361123,978,117 - 24,073,194 (+)NCBIMGSCv36mm8
Celera1126,200,322 - 26,297,352 (+)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Bcl11aMouseautism spectrum disorder  ISORGD:132052711099981DNA:mutations:multiple (human)RGD 
Bcl11aMouseB-Cell Chronic Lymphocytic Leukemia  ISORGD:132052711100004DNA:translocation:5' utr: (human)RGD 
Bcl11aMousebeta thalassemia  ISORGD:132052711100005DNA:snp, haplotype:intron:c.386-24983T>C (rs4671393) (human)RGD 
Bcl11aMousebeta thalassemia severityISORGD:132052711100008DNA:snp:intron:c.386-17267T>C (rs10189857) (human)RGD 
Bcl11aMousebeta thalassemia severityISORGD:132052711099969DNA:snps:intron:c. 386-24002G>T, c.386-24278G>A (rs766432, rs11886868) (human)RGD 
Bcl11aMousebeta thalassemia treatmentISORGD:132052711100011 RGD 
Bcl11aMouselung non-small cell carcinoma severityISORGD:132052711099968mRNA, protein:increased expression:lung (human)RGD 
Bcl11aMouseschizophrenia  ISORGD:132052711099977DNA:snps:multiple (human)RGD 
Bcl11aMousesickle cell anemia treatmentISORGD:132052711100007 RGD 
Bcl11aMousesickle cell anemia severityISORGD:132052711099970DNA:snp, haplotype:intron:c.386-24983T>C (rs4671393) (human)RGD 
Bcl11aMousesickle cell anemia severityIMP 11099996 RGD 
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Bcl11aMouseAgenesis of Corpus Callosum  ISORGD:13205278554872ClinVar Annotator: match by term: Corpus callosum, agenesis ofClinVarPMID:31474318
Bcl11aMousecerebellar hypoplasia  ISORGD:13205278554872ClinVar Annotator: match by term: Congenital cerebellar hypoplasiaClinVarPMID:31474318
Bcl11aMouseDevelopmental Disabilities  ISORGD:13205278554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:25741868|PMID:25741869
Bcl11aMouseDevelopmental Disease  ISORGD:13205278554872ClinVar Annotator: match by term: Developmental disorderClinVarPMID:25741868
Bcl11aMousegenetic disease  ISORGD:13205278554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:12196208|PMID:22542183|PMID:25418537|PMID:25741868|PMID:29985992
Bcl11aMouseINTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN  ISORGD:13205278554872ClinVar Annotator: match by term: BCL11A-related condition | ClinVar Annotator: match by term: BCL11A-related intellectual more ...ClinVarPMID:25741868|PMID:27453576|PMID:28492532|PMID:28891213|PMID:29758562|PMID:31474318|PMID:33116287|PMID:39825153
Bcl11aMouseintellectual disability  ISORGD:13205278554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868
Bcl11aMouseMarfanoid Mental Retardation Syndrome, Autosomal  ISORGD:13205278554872ClinVar Annotator: match by term: Marfanoid habitus and intellectual disabilityClinVarPMID:25741868
Bcl11aMouseNeurodevelopmental Disorders  ISORGD:13205278554872ClinVar Annotator: match by term: Neurodevelopmental abnormalityClinVar 
Bcl11aMousePostaxial Polydactyly  ISORGD:13205278554872ClinVar Annotator: match by term: Postaxial polydactylyClinVarPMID:25741868
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Bcl11aMouseadenoid cystic carcinoma  ISORGD:132052711554173CTD Direct Evidence: marker/mechanismCTDPMID:16762588
Bcl11aMouseapraxia  ISORGD:132052711554173CTD Direct Evidence: marker/mechanismCTDPMID:27120335
Bcl11aMouseCOVID-19  ISORGD:132052711554173CTD Direct Evidence: marker/mechanismCTDPMID:35255492
Bcl11aMouseLanguage Development Disorders  ISORGD:132052711554173CTD Direct Evidence: marker/mechanismCTDPMID:27120335
Bcl11aMousepolycystic ovary syndrome  ISORGD:132052711554173CTD Direct Evidence: marker/mechanismCTDPMID:21411543
Bcl11aMouseSalivary Gland Neoplasms  ISORGD:132052711554173CTD Direct Evidence: marker/mechanismCTDPMID:16762588
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Bcl11aMouseINTELLECTUAL DEVELOPMENTAL DISORDER WITH PERSISTENCE OF FETAL HEMOGLOBIN  ISORGD:13205277240710 OMIM 

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Bcl11aMouse1,2-dichloroethane increases expressionEXP 6480464ethylene dichloride results in increased expression of BCL11A mRNACTDPMID:28960355
Bcl11aMouse1,2-dimethylhydrazine multiple interactionsEXP 6480464[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of BCL11A mRNACTDPMID:22206623
Bcl11aMouse1,3-dinitrobenzene decreases expressionISORGD:130992364804643-dinitrobenzene results in decreased expression of BCL11A mRNACTDPMID:21983209
Bcl11aMouse17alpha-ethynylestradiol multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BCL11A mRNACTDPMID:17942748
Bcl11aMouse17beta-estradiol multiple interactionsISORGD:13205276480464[Estradiol co-treated with Progesterone] results in decreased expression of BCL11A mRNACTDPMID:20660070
Bcl11aMouse17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of BCL11A mRNACTDPMID:39298647
Bcl11aMouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of BCL11A mRNACTDPMID:15652763
Bcl11aMouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of BCL11A mRNACTDPMID:37172768
Bcl11aMouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BCL11A mRNACTDPMID:17942748
Bcl11aMouse2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expressionISORGD:132052764804642,2',4,4',5-brominated diphenyl ether results in decreased expression of BCL11A mRNACTDPMID:26705709
Bcl11aMouse2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionEXP 64804642,2',4,4',5-brominated diphenyl ether affects the expression of BCL11A mRNACTDPMID:38648751
Bcl11aMouse2-methoxyethanol decreases expressionISORGD:13099236480464methyl cellosolve results in decreased expression of BCL11A mRNACTDPMID:21061450
Bcl11aMouse2-methylcholine affects expressionISORGD:13205276480464beta-methylcholine affects the expression of BCL11A mRNACTDPMID:21179406
Bcl11aMouse3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of BCL11A mRNACTDPMID:26251327
Bcl11aMouse3,4-methylenedioxymethamphetamine increases methylationEXP 6480464N-Methyl-3,4-methylenedioxyamphetamine results in increased methylation of BCL11A promoterCTDPMID:26251327
Bcl11aMouse4,4'-sulfonyldiphenol increases expressionISORGD:13205276480464bisphenol S results in increased expression of BCL11A mRNACTDPMID:25912373
Bcl11aMouseacrylamide decreases expressionISORGD:13205276480464Acrylamide results in decreased expression of BCL11A mRNACTDPMID:32763439
Bcl11aMouseaflatoxin B1 increases methylationISORGD:13205276480464Aflatoxin B1 results in increased methylation of BCL11A intronCTDPMID:30157460
Bcl11aMouseAflatoxin B2 alpha increases methylationISORGD:13205276480464aflatoxin B2 results in increased methylation of BCL11A intronCTDPMID:30157460
Bcl11aMousealdehydo-D-glucose multiple interactionsEXP 6480464[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...CTDPMID:37567420

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Biological Process
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Bcl11aMouseB cell differentiation acts_upstream_of_or_withinIMPMGI:26639412290270 PMID:12717432MGIPMID:12717432
Bcl11aMousecellular response to L-glutamate  ISORGD:13099239068941 RGDPMID:20534004|REF_RGD_ID:11100020
Bcl11aMousegene expression acts_upstream_ofIMPMGI:43580882290270 PMID:19657335MGIPMID:19657335
Bcl11aMousenegative regulation of branching morphogenesis of a nerve  ISORGD:13099239068941 RGDPMID:19616629|REF_RGD_ID:11100018
Bcl11aMousenegative regulation of branching morphogenesis of a nerve involved_inISORGD:13099232290270 GO_CentralGO_REF:0000096
Bcl11aMousenegative regulation of collateral sprouting involved_inISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousenegative regulation of dendrite development involved_inISORGD:13099232290270 GO_CentralGO_REF:0000096
Bcl11aMousenegative regulation of dendrite development involved_inISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousenegative regulation of dendrite development involved_inIBAPANTHER:PTN002916321|RGD:1309923|UniProtKB:Q9H1652290270 GO_CentralGO_REF:0000033
Bcl11aMousenegative regulation of dendrite development  ISORGD:13099239068941 RGDPMID:19616629|REF_RGD_ID:11100018
Bcl11aMousenegative regulation of dendrite extension  ISORGD:13099239068941 RGDPMID:19616629|REF_RGD_ID:11100018
Bcl11aMousenegative regulation of dendrite extension involved_inISORGD:13099232290270 GO_CentralGO_REF:0000096
Bcl11aMousenegative regulation of gene expression acts_upstream_of_or_withinIMPMGI:43580882290270 PMID:19657335MGIPMID:19657335
Bcl11aMousenegative regulation of neuron projection development involved_inISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousenegative regulation of neuron remodeling  ISORGD:13099239068941 RGDPMID:19616629|REF_RGD_ID:11100018
Bcl11aMousenegative regulation of neuron remodeling involved_inISORGD:13099232290270 GO_CentralGO_REF:0000096
Bcl11aMousenegative regulation of transcription by RNA polymerase II involved_inIMP 2290270 PMID:29606353ARUK-UCLPMID:29606353
Bcl11aMousenegative regulation of transcription by RNA polymerase II involved_inISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousepositive regulation of collateral sprouting involved_inISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousepositive regulation of gene expression involved_inISORGD:13099232290270 GO_CentralGO_REF:0000096
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Cellular Component
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Bcl11aMousecytoplasm located_inIEAUniProtKB-SubCell:SL-00862290270 UniProtGO_REF:0000044
Bcl11aMousenuclear body located_inIDA 2290270 PMID:18681895UniProtPMID:18681895
Bcl11aMousenucleoplasm located_inISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousenucleus is_active_inIBAPANTHER:PTN001905569|MGI:106190|MGI:1926956|UniProtKB:Q9H165|UniProtKB:Q9C0K0|MGI:1929913|FB:FBgn00112362290270 GO_CentralGO_REF:0000033
Bcl11aMousenucleus located_inIDA 2290270 PMID:10744719MGIPMID:10744719
Bcl11aMousenucleus located_inISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMouseparaspeckles located_inISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousepostsynapse is_active_inISORGD:13099232290270 GO_CentralGO_REF:0000096
Bcl11aMouseSWI/SNF complex part_ofIDA 2290270 PMID:23644491UniProtPMID:23644491
Bcl11aMouseSWI/SNF complex part_ofISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
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Molecular Function
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Bcl11aMouseDNA-binding transcription factor activity enablesIBAPANTHER:PTN001905569|UniProtKB:Q9H165|MGI:1929913|FB:FBgn00112362290270 GO_CentralGO_REF:0000033
Bcl11aMouseDNA-binding transcription factor binding enablesISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMouseDNA-binding transcription repressor activity, RNA polymerase II-specific enablesISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMouseprotein binding enablesIPIUniProtKB:O547142290270 PMID:18681895UniProtPMID:18681895
Bcl11aMouseprotein heterodimerization activity enablesISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMouseprotein homodimerization activity enablesISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMouseprotein kinase binding  ISORGD:620049068941 RGDPMID:20623620|REF_RGD_ID:11100016
Bcl11aMouseprotein kinase binding enablesISORGD:13099232290270 GO_CentralGO_REF:0000096
Bcl11aMouseRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIBAPANTHER:PTN001905569|UniProtKB:Q9H165|FB:FBgn0029939|MGI:19299132290270 GO_CentralGO_REF:0000033
Bcl11aMouseRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousetranscription coregulator activity enablesISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousetranscription corepressor activity enablesIDA 2290270 PMID:10744719MGIPMID:10744719
Bcl11aMousetranscription regulatory region nucleic acid binding enablesISOUniProtKB:Q9H1652290270 GO_CentralGO_REF:0000119
Bcl11aMousezinc ion binding enablesIEAUniProtKB-KW:KW-08632290270 UniProtGO_REF:0000043
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Bcl11aMouseabnormal axon morphology  IAGP 5509061 MGIPMID:22491945
Bcl11aMouseabnormal common lymphocyte progenitor cell morphology  IAGP 5509061 MGIPMID:23230003
Bcl11aMouseabnormal dendritic cell differentiation  IAGP 5509061 MGIPMID:24591644
Bcl11aMouseabnormal erythropoiesis  IAGP 5509061 MGIPMID:19657335
Bcl11aMouseabnormal erythropoiesis  IAGP 5509061 MGIPMID:23361909
Bcl11aMouseabnormal excitatory postsynaptic currents  IAGP 5509061 MGIPMID:22491945
Bcl11aMouseabnormal hematopoietic stem cell physiology  IAGP 5509061 MGIPMID:23230003
Bcl11aMouseabnormal hemoglobin content  IAGP 5509061 MGIPMID:19657335
Bcl11aMouseabnormal immune system morphology  IAGP 5509061 MGIPMID:23230003
Bcl11aMouseabnormal immunoglobulin heavy chain V(D)J recombination  IAGP 5509061 MGIPMID:12717432
Bcl11aMouseabnormal neurite morphology  IAGP 5509061 MGIPMID:22491945
Bcl11aMouseabnormal neuron differentiation  IAGP 5509061 MGIPMID:22491945
Bcl11aMouseabnormal sensory neuron innervation pattern  IAGP 5509061 MGIPMID:22491945
Bcl11aMouseabnormal spinal cord dorsal horn morphology  IAGP 5509061 MGIPMID:22491945
Bcl11aMouseabnormal T cell differentiation  IAGP 5509061 MGIPMID:23230003
Bcl11aMouseabsent B cells  IAGP 5509061 MGIPMID:12717432
Bcl11aMouseabsent B cells  IAGP 5509061 MGIPMID:24591644
Bcl11aMouseabsent CD4-positive, alpha-beta T cells  IAGP 5509061 MGIPMID:12717432
Bcl11aMouseabsent lymphocyte  IAGP 5509061 MGIPMID:24591644
Bcl11aMouseanemia  IAGP 5509061 MGIPMID:23361909
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Reference Title
Reference Citation
1. Genetic Modifiers in beta-Thalassemia Intermedia: A Study on 102 Iraqi Arab Patients. Al-Allawi NA, etal., Genet Test Mol Biomarkers. 2015 May;19(5):242-7. doi: 10.1089/gtmb.2014.0310. Epub 2015 Mar 9.
2. BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations. Basak A, etal., J Clin Invest. 2015 Jun;125(6):2363-8. doi: 10.1172/JCI81163. Epub 2015 May 4.
3. Molecular mechanism of yisui shengxue granule, a complex chinese medicine, on thalassemia patients suffering from hemolysis and anemia of erythrocytes. Chu NL, etal., Evid Based Complement Alternat Med. 2014;2014:213782. doi: 10.1155/2014/213782. Epub 2014 Dec 10.
4. Synaptic, transcriptional and chromatin genes disrupted in autism. De Rubeis S, etal., Nature. 2014 Nov 13;515(7526):209-15. doi: 10.1038/nature13772. Epub 2014 Oct 29.
5. Hydroxycarbamide alters erythroid gene expression in children with sickle cell anaemia. Flanagan JM, etal., Br J Haematol. 2012 Apr;157(2):240-8. doi: 10.1111/j.1365-2141.2012.09061.x. Epub 2012 Feb 24.
6. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
7. Analysis of rs4671393 polymorphism in hemoglobin E/beta-thalassemia major in Guangxi Province of China. He Y, etal., J Pediatr Hematol Oncol. 2012 May;34(4):323-4. doi: 10.1097/MPH.0b013e3182370bff.
8. BCL11A overexpression predicts survival and relapse in non-small cell lung cancer and is modulated by microRNA-30a and gene amplification. Jiang BY, etal., Mol Cancer. 2013 Jun 12;12:61. doi: 10.1186/1476-4598-12-61.
9. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
10. DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. Lettre G, etal., Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11869-74. doi: 10.1073/pnas.0804799105. Epub 2008 Jul 30.
11. MGDs mouse GO annotations MGD data from the GO Consortium
12. MGD IEA MGD IEA
13. The influence of the BCL11A polymorphism on the phenotype of patients with beta thalassemia could be affected by the beta globin locus control region and/or the Xmn1-HBG2 genotypic background. Neishabury M, etal., Blood Cells Mol Dis. 2013 Aug;51(2):80-4. doi: 10.1016/j.bcmd.2013.02.007. Epub 2013 Mar 28.
14. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
15. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16. Mouse MP Annotation Import Pipeline RGD automated import pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. The BCL11 gene family: involvement of BCL11A in lymphoid malignancies. Satterwhite E, etal., Blood. 2001 Dec 1;98(12):3413-20.
20. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing. Xu J, etal., Science. 2011 Nov 18;334(6058):993-6. doi: 10.1126/science.1211053. Epub 2011 Oct 13.
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PMID:8563752   PMID:8889548   PMID:10349636   PMID:10744719   PMID:10757802   PMID:11042159   PMID:11076861   PMID:11161790   PMID:12477932   PMID:12618378   PMID:12717432   PMID:14610273  
PMID:15254596   PMID:15465497   PMID:15489334   PMID:15639232   PMID:16107646   PMID:16141072   PMID:16141073   PMID:16919269   PMID:17207666   PMID:18287559   PMID:18640244   PMID:18681895  
PMID:18948576   PMID:19030180   PMID:19092943   PMID:19386638   PMID:19571125   PMID:19657335   PMID:19799774   PMID:20089898   PMID:21194568   PMID:21267068   PMID:21677750   PMID:21873635  
PMID:22235033   PMID:22491945   PMID:22988430   PMID:23230003   PMID:23361909   PMID:23576758   PMID:23644491   PMID:23741395   PMID:23975195   PMID:24316575   PMID:24371119   PMID:24442869  
PMID:24591644   PMID:24952961   PMID:25330008   PMID:25574598   PMID:25972180   PMID:26182416   PMID:26375006   PMID:26390863   PMID:27100196   PMID:27117402   PMID:27453576   PMID:27653684  
PMID:27707736   PMID:28671696   PMID:28935710   PMID:28942923   PMID:29044125   PMID:29055695   PMID:29513653   PMID:29606353   PMID:29898395   PMID:30127402   PMID:30242153   PMID:34095148  
PMID:34321999   PMID:34525371   PMID:34921112   PMID:34963132   PMID:35156680   PMID:35363520   PMID:35766181   PMID:35805190   PMID:37142655   PMID:37250402   PMID:37524711   PMID:37744176  
PMID:38616731   PMID:39017845   PMID:39159043   PMID:39808658  



Bcl11a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391124,026,498 - 24,123,558 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1124,028,056 - 24,124,123 (+)EnsemblGRCm39 Ensembl
GRCm381124,076,564 - 24,173,558 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1124,078,056 - 24,174,123 (+)EnsemblGRCm38mm10GRCm38
MGSCv371123,978,056 - 24,073,558 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361123,978,117 - 24,073,194 (+)NCBIMGSCv36mm8
Celera1126,200,322 - 26,297,352 (+)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.41NCBI
BCL11A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38260,450,520 - 60,553,924 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl260,450,520 - 60,554,467 (-)EnsemblGRCh38hg38GRCh38
GRCh37260,677,655 - 60,781,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36260,531,806 - 60,634,137 (-)NCBINCBI36Build 36hg18NCBI36
Build 34260,589,952 - 60,692,284NCBI
Celera260,521,903 - 60,624,215 (-)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef260,420,518 - 60,522,477 (-)NCBIHuRef
CHM1_1260,608,322 - 60,710,989 (-)NCBICHM1_1
T2T-CHM13v2.0260,456,325 - 60,559,762 (-)NCBIT2T-CHM13v2.0
Bcl11a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814102,230,147 - 102,325,289 (+)NCBIGRCr8
mRatBN7.21498,029,018 - 98,124,181 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1498,030,461 - 98,124,180 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14102,356,972 - 102,441,929 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014103,601,214 - 103,686,130 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014100,072,890 - 100,157,850 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014108,826,717 - 108,921,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14108,826,831 - 108,921,669 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014108,546,630 - 108,641,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414105,002,744 - 105,088,365 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114105,021,975 - 105,116,487 (+)NCBI
Celera1496,996,223 - 97,081,419 (+)NCBICelera
Cytogenetic Map14q22NCBI
Bcl11a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542423,233,523 - 23,330,679 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542423,233,523 - 23,330,679 (+)NCBIChiLan1.0ChiLan1.0
BCL11A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21265,812,483 - 65,916,535 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A65,816,446 - 65,920,488 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A60,552,908 - 60,655,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A61,695,613 - 61,795,818 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A61,695,613 - 61,795,800 (-)Ensemblpanpan1.1panPan2
BCL11A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11060,589,298 - 60,691,997 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1060,589,708 - 60,689,073 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1060,476,758 - 60,576,928 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01061,594,834 - 61,695,110 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1061,594,834 - 61,695,003 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11061,295,070 - 61,395,145 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01061,582,263 - 61,682,432 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01061,874,607 - 61,974,801 (-)NCBIUU_Cfam_GSD_1.0
Bcl11a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629222,453,189 - 22,549,575 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364916,021,343 - 6,118,568 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364916,021,340 - 6,118,103 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL11A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl381,196,294 - 81,296,382 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1381,195,217 - 81,296,165 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2385,284,350 - 85,384,809 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BCL11A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11446,453,102 - 46,553,802 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604565,253,058 - 65,353,332 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl11a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248331,367,781 - 1,468,400 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248331,367,878 - 1,468,257 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Bcl11a
2450 total Variants

1 to 10 of 543 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh37/hg19 22q11.21(chr22:18915347-21463730)x1 copy number loss VATER association [RCV000520380] Chr22:18915347..21463730 [GRCh37]
Chr22:22q11.21		 likely pathogenic
GRCh37/hg19 22q11.21(chr22:18894835-21464119) copy number gain Global developmental delay [RCV001291954] Chr22:18894835..21464119 [GRCh37]
Chr22:22q11.21		 pathogenic
GRCh37/hg19 22q11.21(chr22:18894835-20311763) copy number loss Astigmatism [RCV000626527] Chr22:18894835..20311763 [GRCh37]
Chr22:22q11.21		 pathogenic
GRCh38/hg38 22q11.21(chr22:18339130-21207225)x3 copy number gain See cases [RCV000050271] Chr22:18339130..21207225 [GRCh38]
Chr22:18919942..21561514 [GRCh37]
Chr22:17299942..19891514 [NCBI36]
Chr22:22q11.21		 pathogenic
GRCh38/hg38 22q11.21(chr22:18339130-21207225)x1 copy number loss See cases [RCV000050273] Chr22:18339130..21207225 [GRCh38]
Chr22:18919942..21561514 [GRCh37]
Chr22:17299942..19891514 [NCBI36]
Chr22:22q11.21		 pathogenic
GRCh38/hg38 22q11.21(chr22:18339130-20671425)x1 copy number loss See cases [RCV000050290] Chr22:18339130..20671425 [GRCh38]
Chr22:18706001..21025713 [GRCh37]
Chr22:17086001..19355713 [NCBI36]
Chr22:22q11.21		 pathogenic
GRCh38/hg38 22q11.21(chr22:18339130-21086225)x3 copy number gain See cases [RCV000050991] Chr22:18339130..21086225 [GRCh38]
Chr22:18919942..21440514 [GRCh37]
Chr22:17299942..19770514 [NCBI36]
Chr22:22q11.21		 pathogenic
GRCh38/hg38 22q11.21(chr22:18339130-21086225)x1 copy number loss See cases [RCV000050992] Chr22:18339130..21086225 [GRCh38]
Chr22:18919942..21440514 [GRCh37]
Chr22:17299942..19770514 [NCBI36]
Chr22:22q11.21		 pathogenic
GRCh38/hg38 22q11.1-11.21(chr22:16916608-20324240)x3 copy number gain See cases [RCV000050858] Chr22:16916608..20324240 [GRCh38]
Chr22:17397498..20311763 [GRCh37]
Chr22:15777498..18691763 [NCBI36]
Chr22:22q11.1-11.21		 pathogenic
GRCh38/hg38 22q11.1-11.21(chr22:16916608-20324240)x1 copy number loss See cases [RCV000050859] Chr22:16916608..20324240 [GRCh38]
Chr22:17397498..20311763 [GRCh37]
Chr22:15777498..18691763 [NCBI36]
Chr22:22q11.1-11.21		 pathogenic
1 to 10 of 543 rows

Predicted Target Of
Summary Value
Count of predictions:1829
Count of miRNA genes:733
Interacting mature miRNAs:943
Transcripts:ENSMUST00000000881, ENSMUST00000109514, ENSMUST00000109516, ENSMUST00000118955, ENSMUST00000124148, ENSMUST00000127494
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 50 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse

1 to 10 of 50 rows
BE447163  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381124,166,994 - 24,167,081UniSTSGRCm38
MGSCv371124,066,994 - 24,067,081UniSTSGRCm37
Celera1126,290,180 - 26,290,267UniSTS
Cytogenetic Map11A3.2UniSTS
Whitehead/MRC_RH11396.54UniSTS
Bcl11a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371124,064,167 - 24,064,546UniSTSGRCm37
Celera1126,287,353 - 26,287,732UniSTS
Cytogenetic Map11A3.2UniSTS
cM Map11 UniSTS
Bcl11a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A3.2UniSTS
cM Map11 UniSTS
Bcl11a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381124,164,167 - 24,164,546UniSTSGRCm38
MGSCv371124,064,167 - 24,064,546UniSTSGRCm37
Celera1126,287,353 - 26,287,732UniSTS
Cytogenetic Map11A3.2UniSTS






1 to 30 of 48 rows
RefSeq Transcripts NM_001159289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001159290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001242934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_016707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006514507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA008362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF051525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF169036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF169037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF186018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 48 rows

Ensembl Acc Id: ENSMUST00000000881   ⟹   ENSMUSP00000000881
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1124,028,056 - 24,123,194 (+)Ensembl
GRCm38.p6 Ensembl1124,078,056 - 24,173,194 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109514   ⟹   ENSMUSP00000105140
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1124,028,173 - 24,118,429 (+)Ensembl
GRCm38.p6 Ensembl1124,078,173 - 24,168,429 (+)Ensembl
Ensembl Acc Id: ENSMUST00000109516   ⟹   ENSMUSP00000105142
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1124,028,117 - 24,124,123 (+)Ensembl
GRCm38.p6 Ensembl1124,078,117 - 24,174,123 (+)Ensembl
Ensembl Acc Id: ENSMUST00000118955   ⟹   ENSMUSP00000112948
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1124,030,670 - 24,123,558 (+)Ensembl
GRCm38.p6 Ensembl1124,080,670 - 24,173,558 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124148
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1124,028,147 - 24,040,906 (+)Ensembl
GRCm38.p6 Ensembl1124,078,147 - 24,090,906 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127494
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1124,092,379 - 24,113,291 (+)Ensembl
GRCm38.p6 Ensembl1124,142,379 - 24,163,291 (+)Ensembl
RefSeq Acc Id: NM_001159289   ⟹   NP_001152761
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,028,056 - 24,123,558 (+)NCBI
GRCm381124,078,056 - 24,173,558 (+)NCBI
MGSCv371123,978,056 - 24,073,558 (+)RGD
Celera1126,200,322 - 26,297,352 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001159290   ⟹   NP_001152762
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,030,695 - 24,123,558 (+)NCBI
GRCm381124,080,695 - 24,173,558 (+)NCBI
MGSCv371123,978,056 - 24,073,558 (+)RGD
Celera1126,200,322 - 26,297,352 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001242934   ⟹   NP_001229863
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,028,056 - 24,118,435 (+)NCBI
GRCm381124,078,056 - 24,168,435 (+)NCBI
Celera1126,200,322 - 26,297,352 (+)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_016707   ⟹   NP_057916
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,028,056 - 24,123,558 (+)NCBI
GRCm381124,078,056 - 24,173,558 (+)NCBI
MGSCv371123,978,056 - 24,073,558 (+)RGD
Celera1126,200,322 - 26,297,352 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006514504   ⟹   XP_006514567
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,564 - 24,118,435 (+)NCBI
GRCm381124,076,564 - 24,168,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006514507   ⟹   XP_006514570
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,030,635 - 24,118,435 (+)NCBI
GRCm381124,078,524 - 24,168,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011243659   ⟹   XP_011241961
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,564 - 24,123,194 (+)NCBI
GRCm381124,076,564 - 24,173,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011243660   ⟹   XP_011241962
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,027,441 - 24,118,435 (+)NCBI
GRCm381124,077,462 - 24,168,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030245543   ⟹   XP_030101403
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,027,441 - 24,123,194 (+)NCBI
GRCm381124,077,490 - 24,173,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030245545   ⟹   XP_030101405
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,030,634 - 24,118,435 (+)NCBI
GRCm381124,080,634 - 24,168,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030245547   ⟹   XP_030101407
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,030,635 - 24,123,194 (+)NCBI
GRCm381124,078,531 - 24,173,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030245548   ⟹   XP_030101408
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,806 - 24,123,194 (+)NCBI
GRCm381124,077,515 - 24,173,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156314   ⟹   XP_036012207
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,564 - 24,123,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156315   ⟹   XP_036012208
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,498 - 24,118,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156316   ⟹   XP_036012209
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,564 - 24,118,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156317   ⟹   XP_036012210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,027,500 - 24,118,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156318   ⟹   XP_036012211
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,545 - 24,118,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156319   ⟹   XP_036012212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,498 - 24,123,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156320   ⟹   XP_036012213
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,498 - 24,123,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156321   ⟹   XP_036012214
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,564 - 24,123,194 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156322   ⟹   XP_036012215
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391124,026,806 - 24,123,194 (+)NCBI
Sequence:
1 to 30 of 46 rows
Protein RefSeqs NP_001152761 (Get FASTA)   NCBI Sequence Viewer  
  NP_001152762 (Get FASTA)   NCBI Sequence Viewer  
  NP_001229863 (Get FASTA)   NCBI Sequence Viewer  
  NP_057916 (Get FASTA)   NCBI Sequence Viewer  
  XP_006514567 (Get FASTA)   NCBI Sequence Viewer  
  XP_006514570 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241961 (Get FASTA)   NCBI Sequence Viewer  
  XP_011241962 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101403 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101405 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101407 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101408 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012207 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012208 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012209 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012210 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012211 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012212 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012213 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012214 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012215 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF22430 (Get FASTA)   NCBI Sequence Viewer  
  AAF63682 (Get FASTA)   NCBI Sequence Viewer  
  AAF65928 (Get FASTA)   NCBI Sequence Viewer  
  AAF65929 (Get FASTA)   NCBI Sequence Viewer  
  AAH10585 (Get FASTA)   NCBI Sequence Viewer  
  AAH51418 (Get FASTA)   NCBI Sequence Viewer  
  BAB23285 (Get FASTA)   NCBI Sequence Viewer  
  BAC31616 (Get FASTA)   NCBI Sequence Viewer  
  BAC32416 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 46 rows
1 to 5 of 25 rows
1 to 5 of 25 rows
RefSeq Acc Id: NP_057916   ⟸   NM_016707
- Peptide Label: isoform 1
- UniProtKB: Q9JLK8 (UniProtKB/Swiss-Prot),   Q9JIT4 (UniProtKB/Swiss-Prot),   Q9D0V2 (UniProtKB/Swiss-Prot),   Q921V4 (UniProtKB/Swiss-Prot),   Q8BWX3 (UniProtKB/Swiss-Prot),   Q8BLR4 (UniProtKB/Swiss-Prot),   Q8BLC7 (UniProtKB/Swiss-Prot),   Q80T89 (UniProtKB/Swiss-Prot),   Q9JLK9 (UniProtKB/Swiss-Prot),   Q9QYE3 (UniProtKB/Swiss-Prot),   Q3US10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001152761   ⟸   NM_001159289
- Peptide Label: isoform 2
- UniProtKB: Q9QYE3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001152762   ⟸   NM_001159290
- Peptide Label: isoform 3
- UniProtKB: Q9QYE3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001229863   ⟸   NM_001242934
- Peptide Label: isoform 4
- UniProtKB: Q3US10 (UniProtKB/TrEMBL),   Q5STS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006514567   ⟸   XM_006514504
- Peptide Label: isoform X1
- UniProtKB: Q5STS9 (UniProtKB/TrEMBL),   Q3US10 (UniProtKB/TrEMBL)
- Sequence:
C2H2-type

Name Modeler Protein Id AA Range Protein Structure
AF-Q9QYE3-F1-model_v2 AlphaFold Q9QYE3 1-773 view protein structure

RGD ID:6820488
Promoter ID:MM_KWN:6708
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:OTTMUST00000011802
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361124,041,431 - 24,041,931 (+)MPROMDB
RGD ID:8674134
Promoter ID:EPDNEW_M15098
Type:initiation region
Name:Bcl11a_1
Description:Mus musculus B cell CLL/lymphoma 11A , transcript variant 3,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15099  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381124,078,034 - 24,078,094EPDNEW
RGD ID:8674136
Promoter ID:EPDNEW_M15099
Type:initiation region
Name:Bcl11a_2
Description:Mus musculus B cell CLL/lymphoma 11A , transcript variant 3,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15098  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381124,080,700 - 24,080,760EPDNEW


1 to 40 of 46 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000000861 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000000881 ENTREZGENE
  ENSMUST00000000881.13 UniProtKB/Swiss-Prot
  ENSMUST00000109514 ENTREZGENE
  ENSMUST00000109516 ENTREZGENE
  ENSMUST00000109516.8 UniProtKB/Swiss-Prot
  ENSMUST00000118955 ENTREZGENE
  ENSMUST00000118955.2 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
InterPro Dev/Hematopoietic_TF UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report mmu:14025 UniProtKB/Swiss-Prot
MGD MGI:106190 ENTREZGENE
NCBI Gene 14025 ENTREZGENE
PANTHER B-CELL LYMPHOMA/LEUKEMIA 11 UniProtKB/Swiss-Prot
  B-CELL LYMPHOMA/LEUKEMIA 11A UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
PhenoGen Bcl11a PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt BC11A_MOUSE UniProtKB/Swiss-Prot
  Q3TP99_MOUSE UniProtKB/TrEMBL
  Q3US10 ENTREZGENE, UniProtKB/TrEMBL
  Q5STS9 ENTREZGENE, UniProtKB/TrEMBL
  Q80T89 ENTREZGENE
  Q8BLC7 ENTREZGENE
  Q8BLR4 ENTREZGENE
  Q8BWX3 ENTREZGENE
  Q921V4 ENTREZGENE
  Q9D0V2 ENTREZGENE
  Q9JIT4 ENTREZGENE
  Q9JLK8 ENTREZGENE
  Q9JLK9 ENTREZGENE
  Q9QYE3 ENTREZGENE
UniProt Secondary Q80T89 UniProtKB/Swiss-Prot
  Q8BLC7 UniProtKB/Swiss-Prot
  Q8BLR4 UniProtKB/Swiss-Prot
1 to 40 of 46 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Bcl11a  BCL11 transcription factor A  Bcl11a  B cell CLL/lymphoma 11A (zinc finger protein)  Symbol and/or name change 5135510 APPROVED
2012-02-07 Bcl11a  B cell CLL/lymphoma 11A (zinc finger protein)  Bcl11a  B-cell CLL/lymphoma 11A (zinc finger protein)  Symbol and/or name change 5135510 APPROVED