Bcl11a (BCL11 transcription factor A) - Rat Genome Database

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Gene: Bcl11a (BCL11 transcription factor A) Chinchilla lanigera
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Symbol: Bcl11a
Name: BCL11 transcription factor A (Ensembl:BAF chromatin remodeling complex subunit BCL11A)
RGD ID: 8909288
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN B cell differentiation (ortholog); cellular response to L-glutamate (ortholog); gene expression (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); apraxia (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: B cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell lymphoma/leukemia 11A; BAF chromatin remodeling complex subunit BCL11A; BCL11A, BAF complex component
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542423,233,523 - 23,330,679 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542423,233,523 - 23,330,679 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Bcl11a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542423,233,523 - 23,330,679 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542423,233,523 - 23,330,679 (+)NCBIChiLan1.0ChiLan1.0
BCL11A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38260,450,520 - 60,553,924 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl260,450,520 - 60,554,467 (-)EnsemblGRCh38hg38GRCh38
GRCh37260,677,655 - 60,780,789 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36260,531,806 - 60,634,137 (-)NCBINCBI36Build 36hg18NCBI36
Build 34260,589,952 - 60,692,284NCBI
Celera260,521,903 - 60,624,215 (-)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef260,420,518 - 60,522,477 (-)NCBIHuRef
CHM1_1260,608,322 - 60,710,989 (-)NCBICHM1_1
T2T-CHM13v2.0260,456,325 - 60,559,762 (-)NCBIT2T-CHM13v2.0
Bcl11a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391124,026,498 - 24,123,558 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1124,028,056 - 24,124,123 (+)EnsemblGRCm39 Ensembl
GRCm381124,076,564 - 24,173,558 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1124,078,056 - 24,174,123 (+)EnsemblGRCm38mm10GRCm38
MGSCv371123,978,056 - 24,073,558 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361123,978,117 - 24,073,194 (+)NCBIMGSCv36mm8
Celera1126,200,322 - 26,297,352 (+)NCBICelera
Cytogenetic Map11A3.2NCBI
cM Map1114.41NCBI
Bcl11a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814102,230,147 - 102,325,289 (+)NCBIGRCr8
mRatBN7.21498,029,018 - 98,124,181 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1498,030,461 - 98,124,180 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx14102,356,972 - 102,441,929 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014103,601,214 - 103,686,130 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014100,072,890 - 100,157,850 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014108,826,717 - 108,921,197 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14108,826,831 - 108,921,669 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014108,546,630 - 108,641,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414105,002,744 - 105,088,365 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114105,021,975 - 105,116,487 (+)NCBI
Celera1496,996,223 - 97,081,419 (+)NCBICelera
Cytogenetic Map14q22NCBI
BCL11A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21265,812,483 - 65,916,535 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A65,816,446 - 65,920,488 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A60,552,908 - 60,655,437 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A61,695,613 - 61,795,818 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A61,695,613 - 61,795,800 (-)Ensemblpanpan1.1panPan2
BCL11A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11060,589,298 - 60,691,997 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1060,589,708 - 60,689,073 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1060,476,758 - 60,576,928 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01061,594,834 - 61,695,110 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1061,594,834 - 61,695,003 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11061,295,070 - 61,395,145 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01061,582,263 - 61,682,432 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01061,874,607 - 61,974,801 (-)NCBIUU_Cfam_GSD_1.0
Bcl11a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629222,453,189 - 22,549,575 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364916,021,343 - 6,118,568 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364916,021,340 - 6,118,103 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL11A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl381,196,294 - 81,296,382 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1381,195,217 - 81,296,165 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2385,284,350 - 85,384,809 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BCL11A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11446,453,102 - 46,553,802 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604565,253,058 - 65,353,332 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl11a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248331,367,781 - 1,468,400 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248331,367,878 - 1,468,257 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000013447   ⟹   ENSCLAP00000013295
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542423,233,523 - 23,326,625 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000013448   ⟹   ENSCLAP00000013296
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542423,234,013 - 23,330,679 (+)Ensembl
RefSeq Acc Id: XM_005385757   ⟹   XP_005385814
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542423,234,013 - 23,330,679 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514702   ⟹   XP_013370156
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542423,234,354 - 23,326,639 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514703   ⟹   XP_013370157
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542423,233,523 - 23,326,639 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514704   ⟹   XP_013370158
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542423,234,354 - 23,326,639 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514705   ⟹   XP_013370159
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542423,236,711 - 23,330,679 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514707   ⟹   XP_013370161
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542423,241,648 - 23,330,679 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514708   ⟹   XP_013370162
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542423,234,354 - 23,330,679 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514709   ⟹   XP_013370163
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542423,234,354 - 23,330,679 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005385814   ⟸   XM_005385757
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VBW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370157   ⟸   XM_013514703
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VBY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370163   ⟸   XM_013514709
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_013370162   ⟸   XM_013514708
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_013370156   ⟸   XM_013514702
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VBY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013370158   ⟸   XM_013514704
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013370159   ⟸   XM_013514705
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013370161   ⟸   XM_013514707
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCLAP00000013295   ⟸   ENSCLAT00000013447
RefSeq Acc Id: ENSCLAP00000013296   ⟸   ENSCLAT00000013448
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009184 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013447 ENTREZGENE
  ENSCLAT00000013447.1 UniProtKB/TrEMBL
  ENSCLAT00000013448 ENTREZGENE
  ENSCLAT00000013448.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Bcl11a ENTREZGENE
PANTHER B-CELL LYMPHOMA/LEUKEMIA 11 UniProtKB/TrEMBL
  B-CELL LYMPHOMA/LEUKEMIA 11A UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A8C2VBW4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VBY4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-11-01 Bcl11a  BCL11 transcription factor A  Bcl11a  BAF chromatin remodeling complex subunit BCL11A  Symbol and/or name change 5135510 APPROVED
2019-01-29 Bcl11a  BAF chromatin remodeling complex subunit BCL11A    BCL11A, BAF complex component  Symbol and/or name change 5135510 APPROVED
2018-11-06 Bcl11a  BCL11A, BAF complex component    B cell CLL/lymphoma 11A  Symbol and/or name change 5135510 APPROVED
2017-12-19 Bcl11a  B cell CLL/lymphoma 11A    B-cell CLL/lymphoma 11A  Symbol and/or name change 5135510 APPROVED
2016-08-03 Bcl11a  B-cell CLL/lymphoma 11A    B-cell CLL/lymphoma 11A (zinc finger protein)  Symbol and/or name change 5135510 APPROVED