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Gene: Fermt1 (fermitin family member 1) Mus musculus
Symbol: Fermt1
Name: fermitin family member 1
Description: Exhibits actin filament binding activity. Involved in several processes, including positive regulation of cell adhesion; regulation of protein transport; and regulation of signal transduction. Localizes to focal adhesion. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; sensory organ; and skin. Used to study Kindler syndrome. Human ortholog(s) of this gene implicated in Kindler syndrome; telangiectasis; and vesiculobullous skin disease. Orthologous to human FERMT1 (fermitin family member 1); PARTICIPATES IN integrin mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5830467P10Rik; fermitin family homolog 1; Kind; Kindlin-1; RP23-308A23.1; unc-112-related protein 1
Homo sapiens (human) : FERMT1 (fermitin family member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fermt1 (fermitin family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fermt1 (fermitin family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FERMT1 (fermitin family member 1)
Canis lupus familiaris (dog) : FERMT1 (fermitin family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fermt1 (fermitin family member 1)
Sus scrofa (pig) : FERMT1 (fermitin family member 1)
Chlorocebus sabaeus (African green monkey) : FERMT1 (fermitin family member 1)
Heterocephalus glaber (naked mole-rat) : Fermt1 (fermitin family member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl2132,904,389 - 132,945,906 (-)EnsemblGRCm38mm10GRCm38
GRCm382132,904,177 - 132,946,036 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372132,729,915 - 132,771,772 (-)NCBIGRCm37mm9NCBIm37
MGSCv362132,595,620 - 132,637,477 (-)NCBImm8
Celera2134,125,730 - 134,167,433 (-)NCBICelera
Cytogenetic Map2F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Fermt1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315646
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.