Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | EXP | | 6480464 | ethylene dichloride results in increased expression of ZFP446 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ZFP446 mRNA | CTD | PMID:22206623 | 1,3-dinitrobenzene | decreases expression | ISO | Zfp446 (Rattus norvegicus) | 6480464 | 3-dinitrobenzene results in decreased expression of ZFP446 mRNA | CTD | PMID:21983209 | 17beta-estradiol | decreases expression | ISO | ZNF446 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ZNF446 mRNA | CTD | PMID:31614463 | 2,4-dinitrotoluene | affects expression | ISO | Zfp446 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of ZFP446 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Zfp446 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of ZFP446 mRNA | CTD | PMID:21346803 | 2-palmitoylglycerol | increases expression | ISO | ZNF446 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of ZNF446 mRNA | CTD | PMID:37199045 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | Zfp446 (Rattus norvegicus) | 6480464 | tetrabromobisphenol A results in increased expression of ZNF446 mRNA | CTD | PMID:27914987 | 4,4'-sulfonyldiphenol | decreases methylation | EXP | | 6480464 | bisphenol S results in decreased methylation of ZFP446 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Zfp446 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFP446 mRNA | CTD | PMID:36041667 | amphetamine | decreases expression | ISO | Zfp446 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of ZFP446 mRNA | CTD | PMID:30779732 | atrazine | increases expression | ISO | Zfp446 (Rattus norvegicus) | 6480464 | Atrazine results in increased expression of ZFP446 mRNA | CTD | PMID:36841081 | bisphenol A | affects methylation | EXP | | 6480464 | bisphenol A affects the methylation of ZFP446 promoter | CTD | PMID:27334623 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ZFP446 mRNA | CTD | PMID:32156529 | bisphenol A | multiple interactions | ISO | Zfp446 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFP446 mRNA | CTD | PMID:36041667 | bisphenol F | multiple interactions | ISO | Zfp446 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ZFP446 mRNA | CTD | PMID:36041667 | buspirone | increases expression | ISO | Zfp446 (Rattus norvegicus) | 6480464 | Buspirone results in increased expression of ZFP446 mRNA | CTD | PMID:24136188 | caffeine | increases phosphorylation | ISO | ZNF446 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of ZNF446 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of ZFP446 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | ZNF446 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ZNF446 gene] | CTD | PMID:28238834 | coumarin | increases phosphorylation | ISO | ZNF446 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of ZNF446 protein | CTD | PMID:35688186 | FR900359 | affects phosphorylation | ISO | ZNF446 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ZNF446 protein | CTD | PMID:37730182 | iron dichloride | decreases expression | ISO | ZNF446 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of ZNF446 mRNA | CTD | PMID:35984750 | levofloxacin | increases expression | ISO | Zfp446 (Rattus norvegicus) | 6480464 | Levofloxacin results in increased expression of ZFP446 mRNA | CTD | PMID:24136188 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ZFP446 mRNA | CTD | PMID:19710929 | resveratrol | multiple interactions | ISO | ZNF446 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of ZNF446 mRNA | CTD | PMID:23557933 | sunitinib | decreases expression | ISO | ZNF446 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ZNF446 mRNA | CTD | PMID:31533062 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of ZFP446 mRNA | CTD | PMID:33045310 | | 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Gene Ontology Annotations Click to see Annotation Detail View
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