Gsn (gelsolin) - Rat Genome Database

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Gene: Gsn (gelsolin) Mus musculus
Analyze
Symbol: Gsn
Name: gelsolin
RGD ID: 1550660
MGI Page MGI
Description: Exhibits phosphatidylinositol 3-kinase catalytic subunit binding activity. Involved in several processes, including actin polymerization or depolymerization; cellular response to interferon-gamma; and positive regulation of protein processing in phagocytic vesicle. Localizes to lamellipodium and phagocytic vesicle. Colocalizes with focal adhesion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Finnish type amyloidosis. Orthologous to human GSN (gelsolin); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; N-cadherin signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: actin-depolymerizing factor; ADF; brevin; MGC28083
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39235,146,371 - 35,197,914 (+)NCBIGRCm39mm39
GRCm39 Ensembl235,146,392 - 35,197,904 (+)Ensembl
GRCm38235,256,359 - 35,307,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl235,256,380 - 35,307,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv37235,137,960 - 35,163,412 (+)NCBIGRCm37mm9NCBIm37
MGSCv36235,104,449 - 35,129,901 (+)NCBImm8
Celera234,977,113 - 35,002,613 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map223.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,5-hexanedione  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
aminoglutethimide  (ISO)
amiodarone  (ISO)
aristolochic acid  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP,ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cumene  (EXP)
curcumin  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDT  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
diethyl maleate  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
fipronil  (ISO)
folic acid  (EXP)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glucose  (ISO)
gold atom  (EXP,ISO)
gold(0)  (EXP,ISO)
GW 4064  (EXP)
hyaluronic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (EXP,ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (EXP)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
microcystin-LR  (EXP)
N-nitrosodimethylamine  (ISO)
navitoclax  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitric oxide  (EXP)
nitroglycerin  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
phenylhydrazine  (EXP)
pirinixic acid  (EXP)
potassium dichromate  (ISO)
progesterone  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
Sodium salicylate  (ISO)
Soman  (ISO)
succimer  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (EXP)
Tesaglitazar  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP)
tetrahydropalmatine  (ISO)
titanium dioxide  (EXP)
toxaphene  (ISO)
trichostatin A  (ISO)
troglitazone  (EXP,ISO)
urethane  (EXP)
valproic acid  (EXP,ISO)
verapamil  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IMP)
actin filament capping  (IDA,ISO)
actin filament depolymerization  (IMP,ISO)
actin filament polymerization  (IDA,ISO)
actin filament reorganization  (ISO)
actin filament severing  (IBA,IMP,ISO)
actin nucleation  (IEA)
actin polymerization or depolymerization  (IBA,ISO)
aging  (ISO)
amyloid fibril formation  (ISO)
apoptotic process  (ISO)
barbed-end actin filament capping  (IBA)
cardiac muscle cell contraction  (IMP)
cell projection assembly  (IBA)
cell projection organization  (IEA)
cellular response to cadmium ion  (ISO)
cellular response to interferon-gamma  (IDA)
central nervous system development  (IBA)
cilium assembly  (ISO)
extracellular matrix disassembly  (ISO)
hepatocyte apoptotic process  (ISO)
negative regulation of viral entry into host cell  (ISO)
oligodendrocyte development  (ISO)
phagocytosis, engulfment  (IMP)
phosphatidylinositol-mediated signaling  (ISO)
positive regulation of actin nucleation  (ISO)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of keratinocyte apoptotic process  (ISO)
positive regulation of protein processing in phagocytic vesicle  (IMP)
protein destabilization  (ISO)
regulation of cell adhesion  (ISO)
regulation of establishment of T cell polarity  (ISO)
regulation of plasma membrane raft polarization  (ISO)
regulation of podosome assembly  (ISO)
regulation of receptor clustering  (ISO)
relaxation of cardiac muscle  (IMP)
renal protein absorption  (ISO)
response to ethanol  (ISO)
response to folic acid  (ISO)
response to muscle stretch  (IMP)
sequestering of actin monomers  (ISO)
striated muscle atrophy  (ISO)
tissue regeneration  (ISO)
vesicle-mediated transport  (IMP)
wound healing  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1315305   PMID:2546951   PMID:7523108   PMID:7698245   PMID:7720072   PMID:7774911   PMID:8075499   PMID:8088777   PMID:8799160   PMID:9298983   PMID:9323209   PMID:9819354  
PMID:9927495   PMID:10349636   PMID:10417819   PMID:10431814   PMID:10556799   PMID:10559185   PMID:10684249   PMID:10922068   PMID:10946270   PMID:10985859   PMID:11042159   PMID:11076861  
PMID:11130978   PMID:11217851   PMID:11423996   PMID:11514591   PMID:12270712   PMID:12477932   PMID:12578912   PMID:12654637   PMID:14610273   PMID:14617805   PMID:14681479   PMID:14691545  
PMID:14962741   PMID:15135218   PMID:15489334   PMID:15671163   PMID:15782199   PMID:16059910   PMID:16120646   PMID:16141072   PMID:16141073   PMID:16261560   PMID:16507893   PMID:16602821  
PMID:16638805   PMID:16829211   PMID:16894625   PMID:16959763   PMID:17192468   PMID:17538019   PMID:18554416   PMID:19015235   PMID:19144319   PMID:19202007   PMID:19213772   PMID:19246681  
PMID:19706712   PMID:20014276   PMID:20203201   PMID:20395300   PMID:20534669   PMID:20661277   PMID:20890741   PMID:21118511   PMID:21267068   PMID:21565611   PMID:21677750   PMID:21779330  
PMID:21828045   PMID:21873635   PMID:22008794   PMID:22108804   PMID:22139132   PMID:22271892   PMID:22421965   PMID:22445754   PMID:22633459   PMID:22922362   PMID:23022035   PMID:23055941  
PMID:23079629   PMID:23259946   PMID:23325791   PMID:24006456   PMID:24133214   PMID:24154525   PMID:24457600   PMID:24475274   PMID:24614889   PMID:24623780   PMID:24770705   PMID:25164111  
PMID:25478578   PMID:25661391   PMID:26084219   PMID:26166300   PMID:26224859   PMID:26364302   PMID:26370502   PMID:26878213   PMID:26928066   PMID:27160897   PMID:27507650   PMID:28118027  
PMID:28193690   PMID:28334940   PMID:28378742   PMID:28385809   PMID:28671696   PMID:28706196   PMID:28814713   PMID:29168693   PMID:29274870   PMID:29518331   PMID:29676259   PMID:29684438  
PMID:30177722   PMID:30568254   PMID:31116980   PMID:32325033  


Genomics

Comparative Map Data
Gsn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39235,146,371 - 35,197,914 (+)NCBIGRCm39mm39
GRCm39 Ensembl235,146,392 - 35,197,904 (+)Ensembl
GRCm38235,256,359 - 35,307,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl235,256,380 - 35,307,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv37235,137,960 - 35,163,412 (+)NCBIGRCm37mm9NCBIm37
MGSCv36235,104,449 - 35,129,901 (+)NCBImm8
Celera234,977,113 - 35,002,613 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map223.5NCBI
GSN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl9121,207,794 - 121,332,843 (+)EnsemblGRCh38hg38GRCh38
GRCh389121,201,483 - 121,332,844 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379123,963,761 - 124,095,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369123,070,201 - 123,134,941 (+)NCBINCBI36hg18NCBI36
Build 349121,109,960 - 121,174,674NCBI
Celera994,678,898 - 94,743,628 (+)NCBI
Cytogenetic Map9q33.2NCBI
HuRef993,648,171 - 93,712,883 (+)NCBIHuRef
CHM1_19124,177,269 - 124,242,004 (+)NCBICHM1_1
Gsn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2318,585,166 - 18,638,404 (+)NCBI
Rnor_6.0 Ensembl314,467,330 - 14,508,911 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0314,456,106 - 14,508,922 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0319,773,655 - 19,826,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4314,360,245 - 14,386,313 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1314,256,616 - 14,282,685 (+)NCBI
Celera313,325,045 - 13,351,501 (+)NCBICelera
Cytogenetic Map3p11NCBI
Gsn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554196,682,058 - 6,733,361 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554196,682,202 - 6,733,361 (-)NCBIChiLan1.0ChiLan1.0
GSN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19120,741,148 - 120,805,831 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9120,741,148 - 120,805,831 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0992,413,819 - 92,460,483 (+)NCBIMhudiblu_PPA_v0panPan3
GSN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11174,248,227 - 74,268,129 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1174,233,457 - 74,268,129 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1172,637,556 - 72,678,974 (+)NCBI
ROS_Cfam_1.01175,364,194 - 75,405,704 (+)NCBI
UMICH_Zoey_3.11173,871,291 - 73,912,586 (+)NCBI
UNSW_CanFamBas_1.01173,902,056 - 73,943,469 (+)NCBI
UU_Cfam_GSD_1.01174,663,262 - 74,683,140 (+)NCBI
Gsn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947189,981,162 - 190,034,252 (+)NCBI
SpeTri2.0NW_0049364879,749,755 - 9,802,787 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1261,295,713 - 261,385,287 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11261,295,711 - 261,372,848 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21293,381,825 - 293,388,559 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GSN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11218,253,079 - 18,317,285 (-)NCBI
ChlSab1.1 Ensembl1218,253,324 - 18,285,938 (-)Ensembl
Vero_WHO_p1.0NW_02366603524,700,374 - 24,764,693 (+)NCBI
Gsn
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476013,943,680 - 14,004,660 (-)NCBI

Position Markers
Gsn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37235,139,442 - 35,139,507UniSTSGRCm37
Celera234,978,595 - 34,978,660UniSTS
Cytogenetic Map2BUniSTS
cM Map224.5UniSTS
cM Map224.5UniSTS
Gsn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38235,283,922 - 35,283,987UniSTSGRCm38
MGSCv37235,139,442 - 35,139,507UniSTSGRCm37
Celera234,978,595 - 34,978,660UniSTS
Cytogenetic Map2BUniSTS
Gsn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
cM Map224.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388608993591306Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2778910341789249Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2834628442346384Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2841803942418228Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2949443443494563Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2949443443494563Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212472666726109Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21432455548324701Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357829Lvrq1_mliver weight QTL 1 (mouse)Not determined220892967119064359Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220892967119064359Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220892967119064359Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220892967119064359Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220892967119064359Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2123971355239859Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22123971355239859Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22379913357799257Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224334620148858457Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22470000055000000Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22541803957081799Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22713263056506216Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22771204884183040Mouse
14746979Manh51_mmandible shape 51 (mouse)22907111763071117Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22907111763071117Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229417935148533014Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23131302344618192Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31324555105313225Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:574
Count of miRNA genes:399
Interacting mature miRNAs:456
Transcripts:ENSMUST00000028239, ENSMUST00000124323, ENSMUST00000139867, ENSMUST00000142324
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001206367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_146120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK076156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL773523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY064133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY144206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY195027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY655071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN701174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000028239   ⟹   ENSMUSP00000028239
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl235,282,380 - 35,307,892 (+)Ensembl
RefSeq Acc Id: ENSMUST00000124323
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl235,282,513 - 35,285,025 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139867   ⟹   ENSMUSP00000144217
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl235,256,449 - 35,290,447 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142324   ⟹   ENSMUSP00000118120
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl235,256,409 - 35,293,567 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201185   ⟹   ENSMUSP00000144561
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl235,256,380 - 35,307,890 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202899   ⟹   ENSMUSP00000144470
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl235,256,396 - 35,293,569 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202990   ⟹   ENSMUSP00000144296
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl235,256,384 - 35,303,251 (+)Ensembl
RefSeq Acc Id: NM_001206367   ⟹   NP_001193296
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)ENTREZGENE
Celera234,951,052 - 35,002,623 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001206368   ⟹   NP_001193297
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)ENTREZGENE
Celera234,951,052 - 35,002,623 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001206369   ⟹   NP_001193298
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,156,756 - 35,197,914 (+)NCBI
GRCm38235,266,744 - 35,307,902 (+)NCBI
Celera234,951,052 - 35,002,623 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001362945   ⟹   NP_001349874
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001362947   ⟹   NP_001349876
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001362948   ⟹   NP_001349877
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)NCBI
Sequence:
RefSeq Acc Id: NM_146120   ⟹   NP_666232
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,172,392 - 35,197,914 (+)NCBI
GRCm38235,282,380 - 35,307,902 (+)NCBI
MGSCv37235,137,960 - 35,163,412 (+)RGD
Celera234,951,052 - 35,002,623 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006497990   ⟹   XP_006498053
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,172,406 - 35,197,909 (+)NCBI
GRCm38235,282,389 - 35,307,897 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001193296 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193297 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193298 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349874 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349876 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349877 (Get FASTA)   NCBI Sequence Viewer  
  NP_666232 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498053 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37677 (Get FASTA)   NCBI Sequence Viewer  
  AAH23143 (Get FASTA)   NCBI Sequence Viewer  
  AAH60377 (Get FASTA)   NCBI Sequence Viewer  
  BAC36223 (Get FASTA)   NCBI Sequence Viewer  
  BAC41004 (Get FASTA)   NCBI Sequence Viewer  
  BAE25485 (Get FASTA)   NCBI Sequence Viewer  
  BAE27574 (Get FASTA)   NCBI Sequence Viewer  
  BAE28702 (Get FASTA)   NCBI Sequence Viewer  
  BAE29494 (Get FASTA)   NCBI Sequence Viewer  
  BAE30608 (Get FASTA)   NCBI Sequence Viewer  
  BAE31661 (Get FASTA)   NCBI Sequence Viewer  
  BAE39054 (Get FASTA)   NCBI Sequence Viewer  
  BAE39126 (Get FASTA)   NCBI Sequence Viewer  
  BAE39925 (Get FASTA)   NCBI Sequence Viewer  
  BAE40358 (Get FASTA)   NCBI Sequence Viewer  
  BAE40410 (Get FASTA)   NCBI Sequence Viewer  
  BAE40549 (Get FASTA)   NCBI Sequence Viewer  
  BAE40566 (Get FASTA)   NCBI Sequence Viewer  
  BAE40830 (Get FASTA)   NCBI Sequence Viewer  
  BAE41291 (Get FASTA)   NCBI Sequence Viewer  
  EDL08646 (Get FASTA)   NCBI Sequence Viewer  
  EDL08647 (Get FASTA)   NCBI Sequence Viewer  
  EDL08648 (Get FASTA)   NCBI Sequence Viewer  
  P13020 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_666232   ⟸   NM_146120
- Peptide Label: isoform 1 precursor
- UniProtKB: P13020 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193296   ⟸   NM_001206367
- Peptide Label: isoform 2
- UniProtKB: Q6PAC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193297   ⟸   NM_001206368
- Peptide Label: isoform 2
- UniProtKB: Q6PAC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193298   ⟸   NM_001206369
- Peptide Label: isoform 2
- UniProtKB: Q6PAC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498053   ⟸   XM_006497990
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001349874   ⟸   NM_001362945
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001349876   ⟸   NM_001362947
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001349877   ⟸   NM_001362948
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000144217   ⟸   ENSMUST00000139867
RefSeq Acc Id: ENSMUSP00000144470   ⟸   ENSMUST00000202899
RefSeq Acc Id: ENSMUSP00000144296   ⟸   ENSMUST00000202990
RefSeq Acc Id: ENSMUSP00000028239   ⟸   ENSMUST00000028239
RefSeq Acc Id: ENSMUSP00000118120   ⟸   ENSMUST00000142324
RefSeq Acc Id: ENSMUSP00000144561   ⟸   ENSMUST00000201185
Protein Domains
Gelsolin-like

Promoters
RGD ID:6831547
Promoter ID:MM_KWN:28883
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   MEF_B6
Transcripts:OTTMUST00000030969
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36235,134,221 - 35,135,247 (+)MPROMDB
RGD ID:6831546
Promoter ID:MM_KWN:28884
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung,   MEF_B6
Transcripts:OTTMUST00000028765,   OTTMUST00000030967,   OTTMUST00000030968
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36235,137,391 - 35,137,927 (+)MPROMDB
RGD ID:6847659
Promoter ID:MM_ACW:28092
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   Lung,   MEF_B6
Transcripts:GSN.HSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36235,157,751 - 35,158,277 (+)MPROMDB
RGD ID:6847656
Promoter ID:MM_ACW:28093
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:GSN.KSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36235,159,826 - 35,160,326 (+)MPROMDB
RGD ID:6877124
Promoter ID:EPDNEW_M2013
Type:initiation region
Name:Gsn_1
Description:Mus musculus gelsolin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2014  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38235,256,422 - 35,256,482EPDNEW
RGD ID:6877126
Promoter ID:EPDNEW_M2014
Type:initiation region
Name:Gsn_2
Description:Mus musculus gelsolin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2013  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38235,266,840 - 35,266,900EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95851 AgrOrtholog
Ensembl Genes ENSMUSG00000026879 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000028239 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000118120 UniProtKB/TrEMBL
  ENSMUSP00000144217 UniProtKB/TrEMBL
  ENSMUSP00000144296 UniProtKB/TrEMBL
  ENSMUSP00000144470 UniProtKB/TrEMBL
  ENSMUSP00000144561 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028239 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000139867 UniProtKB/TrEMBL
  ENSMUST00000142324 UniProtKB/TrEMBL
  ENSMUST00000201185 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000202899 UniProtKB/TrEMBL
  ENSMUST00000202990 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CapG UniProtKB/TrEMBL
  Gelsolin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gelsolin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Villin/Gelsolin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:227753 UniProtKB/Swiss-Prot
MGD MGI:95851 ENTREZGENE
NCBI Gene 227753 ENTREZGENE
PANTHER PTHR11977 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11977:SF27 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11977:SF29 UniProtKB/TrEMBL
Pfam Gelsolin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gsn PhenoGen
PRINTS GELSOLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0J9YUJ8_MOUSE UniProtKB/TrEMBL
  A0A0J9YUQ8_MOUSE UniProtKB/TrEMBL
  A6PWS5_MOUSE UniProtKB/TrEMBL
  GELS_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TGJ9_MOUSE UniProtKB/TrEMBL
  Q3U9Q8_MOUSE UniProtKB/TrEMBL
  Q3UCW8_MOUSE UniProtKB/TrEMBL
  Q6PAC1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0J9YV37 UniProtKB/TrEMBL
  Q3UPB1 UniProtKB/Swiss-Prot
  Q8R590 UniProtKB/Swiss-Prot