Gsn (gelsolin) - Rat Genome Database

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Gene: Gsn (gelsolin) Mus musculus
Analyze
Symbol: Gsn
Name: gelsolin
RGD ID: 1550660
MGI Page MGI
Description: Enables phosphatidylinositol 3-kinase catalytic subunit binding activity. Involved in several processes, including actin filament capping; actin polymerization or depolymerization; and positive regulation of protein processing in phagocytic vesicle. Acts upstream of or within cellular response to type II interferon and vesicle-mediated transport. Located in lamellipodium and phagocytic vesicle. Colocalizes with focal adhesion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Finnish type amyloidosis. Orthologous to human GSN (gelsolin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actin-depolymerizing factor; ADF; brevin; MGC28083
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39235,146,371 - 35,197,914 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl235,146,392 - 35,197,904 (+)EnsemblGRCm39 Ensembl
GRCm38235,256,359 - 35,307,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl235,256,380 - 35,307,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv37235,137,960 - 35,163,412 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36235,104,449 - 35,129,901 (+)NCBIMGSCv36mm8
Celera234,977,113 - 35,002,613 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map223.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,5-hexanedione  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-bromohexadecanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
aminoglutethimide  (ISO)
amiodarone  (ISO)
amitrole  (ISO)
arabinogalactan  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (ISO)
butyric acid  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
cantharidin  (EXP)
carbon nanotube  (EXP,ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
corosolic acid  (ISO)
cumene  (EXP)
Cuprizon  (ISO)
curcumin  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDE  (ISO)
DDT  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
diethyl maleate  (EXP)
dimethylselenide  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
fipronil  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glucose  (ISO)
gold atom  (EXP,ISO)
gold(0)  (EXP,ISO)
GW 4064  (EXP)
hyaluronic acid  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroxyl  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
inulin  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (EXP)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
microcystin-LR  (EXP)
Muraglitazar  (ISO)
N-nitrosodimethylamine  (ISO)
navitoclax  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitric oxide  (EXP)
nitroglycerin  (ISO)
ozone  (EXP,ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
phenylhydrazine  (EXP)
pirinixic acid  (EXP)
potassium dichromate  (ISO)
progesterone  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
Sodium salicylate  (ISO)
Soman  (ISO)
succimer  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (EXP)
Tesaglitazar  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP)
tetrahydropalmatine  (ISO)
thapsigargin  (ISO)
titanium dioxide  (EXP)
toxaphene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP,ISO)
urethane  (EXP)
valproic acid  (EXP,ISO)
verapamil  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IMP)
actin filament capping  (IDA,ISO)
actin filament depolymerization  (IMP,ISO)
actin filament organization  (ISO)
actin filament polymerization  (IDA,ISO)
actin filament severing  (IBA,IMP,ISO,ISS)
actin polymerization or depolymerization  (IBA,ISO)
amyloid fibril formation  (ISO)
barbed-end actin filament capping  (IBA)
cardiac muscle cell contraction  (IMP)
cell projection assembly  (IBA)
cell projection organization  (IEA)
cellular response to cadmium ion  (ISO)
cellular response to type II interferon  (IDA)
central nervous system development  (IBA)
cilium assembly  (ISO,ISS)
extracellular matrix disassembly  (ISO)
hepatocyte apoptotic process  (IEA,ISO)
negative regulation of viral entry into host cell  (ISO)
oligodendrocyte development  (ISO)
phagocytosis, engulfment  (IMP)
positive regulation of actin nucleation  (ISO)
positive regulation of cardiac muscle hypertrophy  (ISO)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway  (IEA,ISO)
positive regulation of gene expression  (ISO)
positive regulation of keratinocyte apoptotic process  (ISO)
positive regulation of p38MAPK cascade  (ISO)
positive regulation of protein processing in phagocytic vesicle  (IMP)
protein destabilization  (ISO)
regulation of establishment of T cell polarity  (ISO)
regulation of plasma membrane raft polarization  (IEA,ISO)
regulation of podosome assembly  (ISO)
regulation of receptor clustering  (ISO)
relaxation of cardiac muscle  (IMP)
renal protein absorption  (ISO)
response to ethanol  (ISO)
response to folic acid  (ISO)
response to muscle stretch  (IMP)
sequestering of actin monomers  (IEA,ISO)
striated muscle atrophy  (IEA,ISO)
tissue regeneration  (ISO)
vesicle-mediated transport  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Plasma gelsolin as a biomarker of acute rheumatic carditis. Argun M, etal., Cardiol Young. 2015 Oct;25(7):1276-80. doi: 10.1017/S1047951114002327. Epub 2014 Nov 18.
2. Widespread loss of gelsolin in breast cancers of humans, mice, and rats. Asch HL, etal., Cancer Res. 1996 Nov 1;56(21):4841-5.
3. Pulmonary vascular permeability and ischemic injury in gelsolin-deficient mice. Becker PM, etal., Am J Respir Cell Mol Biol. 2003 Apr;28(4):478-84. doi: 10.1165/rcmb.2002-0024OC.
4. Altered plasma-type gelsolin and amyloid-β in neonates with hypoxic-ischaemic encephalopathy under therapeutic hypothermia. Benavente-Fernandez I, etal., J Cereb Blood Flow Metab. 2019 Jul;39(7):1349-1354. doi: 10.1177/0271678X18757419. Epub 2018 Feb 21.
5. Gelsolin and Progression of Aortic Arch Calcification in Chronic Hemodialysis Patients. Chiou TT, etal., Int J Med Sci. 2016 Jan 29;13(2):92-8. doi: 10.7150/ijms.13785. eCollection 2016.
6. Neuroprotective effects of gelsolin during murine stroke. Endres M, etal., J Clin Invest. 1999 Feb;103(3):347-54. doi: 10.1172/JCI4953.
7. The cytoskeleton in 'couch potato-ism': Insights from a murine model of impaired actin dynamics. Gertz K, etal., Exp Neurol. 2018 Aug;306:34-44. doi: 10.1016/j.expneurol.2018.04.004. Epub 2018 Apr 21.
8. Plasma gelsolin levels and 1-year mortality after first-ever ischemic stroke. Guo XC, etal., J Crit Care. 2011 Dec;26(6):608-12. doi: 10.1016/j.jcrc.2011.02.007. Epub 2011 Apr 9.
9. Protective effects of gelsolin in acute pulmonary thromboembolism and thrombosis in the carotid artery of mice. Gupta AK, etal., PLoS One. 2019 Apr 19;14(4):e0215717. doi: 10.1371/journal.pone.0215717. eCollection 2019.
10. Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/GSN axis in aging rats. Hu WS, etal., Environ Toxicol. 2019 Jan;34(1):5-12. doi: 10.1002/tox.22651. Epub 2018 Sep 21.
11. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
12. Mutation in gelsolin gene in Finnish hereditary amyloidosis. Levy E, etal., J Exp Med. 1990 Dec 1;172(6):1865-7.
13. Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis. Li GH, etal., Circ Res. 2009 Apr 10;104(7):896-904. doi: 10.1161/CIRCRESAHA.108.172882. Epub 2009 Feb 26.
14. Larch Arabinogalactan Attenuates Myocardial Injury by Inhibiting Apoptotic Cascades in a Rat Model of Ischemia-Reperfusion. Lim SH, J Med Food. 2017 Jul;20(7):691-699. doi: 10.1089/jmf.2016.3886. Epub 2017 Jun 16.
15. Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end. Mejillano MR, etal., Cell 2004 Aug 6;118(3):363-73.
16. MGDs mouse GO annotations MGD data from the GO Consortium
17. Gene expression profile changes are commonly modulated across models and species after traumatic brain injury. Natale JE, etal., J Neurotrauma. 2003 Oct;20(10):907-27.
18. Gelsolin gene expression is upregulated in damaged rat and human livers within non-parenchymal cells and not in hepatocytes. Neubauer K, etal., Histochem Cell Biol. 2003 Oct;120(4):265-75. Epub 2003 Aug 28.
19. Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men. Nishimura H, etal., Mol Cell 1999 Jan;3(1):1-10.
20. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
21. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
22. Plasma gelsolin levels and outcomes after aneurysmal subarachnoid hemorrhage. Pan JW, etal., Crit Care. 2013 Jul 23;17(4):R149. doi: 10.1186/cc12828.
23. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
24. Gelsolin immunoreactivity and development of the tectorial membrane in the cochlea of normal and hypothyroid rats. Rabie A, etal., Cell Tissue Res. 1988 Oct;254(1):241-5.
25. Mouse MP Annotation Import Pipeline RGD automated import pipeline
26. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
27. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
28. Lack of gelsolin promotes perpetuation of atrial fibrillation in the mouse heart. Schrickel JW, etal., J Interv Card Electrophysiol. 2009 Oct;26(1):3-10. doi: 10.1007/s10840-009-9425-4. Epub 2009 Aug 8.
29. Cognitive Impairment and Brain and Peripheral Alterations in a Murine Model of Intraventricular Hemorrhage in the Preterm Newborn. Segado-Arenas A, etal., Mol Neurobiol. 2018 Jun;55(6):4896-4910. doi: 10.1007/s12035-017-0693-1. Epub 2017 Jul 28.
30. Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia. Sigurdsson MI, etal., Genome Med. 2016 Dec 6;8(1):127. doi: 10.1186/s13073-016-0381-1.
31. Circulating actin-gelsolin complexes following oleic acid-induced lung injury. Smith DB, etal., Am J Pathol. 1988 Feb;130(2):261-7.
32. Decreased plasma gelsolin concentrations in acute liver failure, myocardial infarction, septic shock, and myonecrosis. Suhler E, etal., Crit Care Med. 1997 Apr;25(4):594-8. doi: 10.1097/00003246-199704000-00007.
33. Investigation of the actin scavenging system in pre-eclampsia. Tannetta DS, etal., Eur J Obstet Gynecol Reprod Biol. 2014 Jan;172:32-5. doi: 10.1016/j.ejogrb.2013.10.022. Epub 2013 Oct 25.
34. Expression of Cytoplasmic Gelsolin in Rat Brain After Experimental Subarachnoid Hemorrhage. Xie GB, etal., Cell Mol Neurobiol. 2015 Jul;35(5):723-31. doi: 10.1007/s10571-015-0168-8. Epub 2015 Mar 6.
35. Inhibition of histone deacetylation protects wildtype but not gelsolin-deficient mice from ischemic brain injury. Yildirim F, etal., Exp Neurol. 2008 Apr;210(2):531-42. doi: 10.1016/j.expneurol.2007.11.031. Epub 2007 Dec 23.
36. Significant reduction of plasma gelsolin levels in patients with intracerebral hemorrhage. Zhao DQ, etal., Clin Chim Acta. 2013 Jan 16;415:202-6. doi: 10.1016/j.cca.2012.10.048. Epub 2012 Nov 7.
Additional References at PubMed
PMID:1315305   PMID:2546951   PMID:7523108   PMID:7698245   PMID:7720072   PMID:7774911   PMID:8075499   PMID:8088777   PMID:8799160   PMID:9298983   PMID:9323209   PMID:9819354  
PMID:10349636   PMID:10417819   PMID:10431814   PMID:10556799   PMID:10559185   PMID:10684249   PMID:10922068   PMID:10946270   PMID:10985859   PMID:11042159   PMID:11076861   PMID:11130978  
PMID:11217851   PMID:11423996   PMID:11514591   PMID:12270712   PMID:12477932   PMID:12578912   PMID:14610273   PMID:14617805   PMID:14681479   PMID:14691545   PMID:14962741   PMID:15135218  
PMID:15489334   PMID:15671163   PMID:15782199   PMID:16059910   PMID:16120646   PMID:16141072   PMID:16141073   PMID:16261560   PMID:16507893   PMID:16602821   PMID:16638805   PMID:16829211  
PMID:16894625   PMID:16959763   PMID:17192468   PMID:17538019   PMID:18554416   PMID:19015235   PMID:19144319   PMID:19202007   PMID:19213772   PMID:19706712   PMID:20014276   PMID:20203201  
PMID:20395300   PMID:20534669   PMID:20661277   PMID:20890741   PMID:21118511   PMID:21267068   PMID:21565611   PMID:21677750   PMID:21779330   PMID:21828045   PMID:21873635   PMID:22008794  
PMID:22108804   PMID:22139132   PMID:22271892   PMID:22421965   PMID:22445754   PMID:22633459   PMID:22794259   PMID:22922362   PMID:23022035   PMID:23055941   PMID:23079629   PMID:23259946  
PMID:23325791   PMID:24006456   PMID:24133214   PMID:24154525   PMID:24457600   PMID:24475274   PMID:24614889   PMID:24623780   PMID:24770705   PMID:25164111   PMID:25478578   PMID:25661391  
PMID:26084219   PMID:26166300   PMID:26224859   PMID:26364302   PMID:26370502   PMID:26878213   PMID:26928066   PMID:27160897   PMID:27507650   PMID:28118027   PMID:28193690   PMID:28334940  
PMID:28378742   PMID:28385809   PMID:28671696   PMID:28706196   PMID:28814713   PMID:29168693   PMID:29274870   PMID:29382714   PMID:29518331   PMID:29676259   PMID:30177722   PMID:30568254  
PMID:31116980   PMID:32325033   PMID:32554809   PMID:34081922   PMID:34549830   PMID:34896365   PMID:34948078   PMID:35451126   PMID:36114006   PMID:36293380   PMID:36522181   PMID:37126682  
PMID:37142655   PMID:38777258  


Genomics

Comparative Map Data
Gsn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39235,146,371 - 35,197,914 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl235,146,392 - 35,197,904 (+)EnsemblGRCm39 Ensembl
GRCm38235,256,359 - 35,307,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl235,256,380 - 35,307,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv37235,137,960 - 35,163,412 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36235,104,449 - 35,129,901 (+)NCBIMGSCv36mm8
Celera234,977,113 - 35,002,613 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map223.5NCBI
GSN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389121,201,483 - 121,332,842 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9121,207,794 - 121,332,843 (+)EnsemblGRCh38hg38GRCh38
GRCh379123,963,761 - 124,095,120 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369123,070,201 - 123,134,941 (+)NCBINCBI36Build 36hg18NCBI36
Build 349121,109,960 - 121,174,674NCBI
Celera994,678,898 - 94,743,628 (+)NCBICelera
Cytogenetic Map9q33.2NCBI
HuRef993,648,171 - 93,712,883 (+)NCBIHuRef
CHM1_19124,177,269 - 124,242,004 (+)NCBICHM1_1
T2T-CHM13v2.09133,397,510 - 133,528,852 (+)NCBIT2T-CHM13v2.0
Gsn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8338,982,605 - 39,035,849 (+)NCBIGRCr8
mRatBN7.2318,585,166 - 18,638,404 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl318,585,172 - 18,638,402 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx321,683,799 - 21,710,538 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0330,268,837 - 30,295,574 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0328,522,714 - 28,549,446 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0314,456,106 - 14,508,922 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl314,467,330 - 14,508,911 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0319,773,655 - 19,826,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4314,360,245 - 14,386,313 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1314,256,616 - 14,282,685 (+)NCBI
Celera313,325,045 - 13,351,501 (+)NCBICelera
Cytogenetic Map3p11NCBI
Gsn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554196,682,058 - 6,733,361 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554196,682,202 - 6,733,361 (-)NCBIChiLan1.0ChiLan1.0
GSN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21118,011,809 - 18,076,682 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1918,014,159 - 18,079,040 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0992,413,819 - 92,460,483 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19120,741,148 - 120,805,831 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9120,741,148 - 120,805,831 (+)Ensemblpanpan1.1panPan2
GSN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11174,248,227 - 74,268,129 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1174,233,457 - 74,268,129 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1172,637,556 - 72,678,974 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01175,364,194 - 75,405,704 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1175,364,181 - 75,405,705 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11173,871,291 - 73,912,586 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01173,902,056 - 73,943,469 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01174,663,262 - 74,683,140 (+)NCBIUU_Cfam_GSD_1.0
Gsn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947189,981,162 - 190,034,252 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364879,764,944 - 9,802,841 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364879,749,755 - 9,802,787 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1261,307,008 - 261,372,848 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11261,295,711 - 261,372,848 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21293,381,825 - 293,388,559 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GSN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11218,253,079 - 18,317,285 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1218,253,324 - 18,285,938 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603524,700,374 - 24,764,693 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gsn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476013,943,888 - 13,969,905 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476013,943,680 - 14,004,660 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gsn
1269 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:574
Count of miRNA genes:399
Interacting mature miRNAs:456
Transcripts:ENSMUST00000028239, ENSMUST00000124323, ENSMUST00000139867, ENSMUST00000142324
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
12904005Cfq2_mconditioned fear QTL 2 (mouse)22702264256396228Mouse
14746979Manh51_mmandible shape 51 (mouse)22896112962961129Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
12904008Cfq6_mconditioned fear QTL 6 (mouse)23120303544508204Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
14746997Mancz2_mmandible centroid size 2 (mouse)22896112962961129Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
13464253Ifvrq1_minfluenza virus resistance QTL 1 (mouse)23303449252034492Mouse
1300577Capsq1_mcapsaicin sensitivity related QTL 1 (mouse)Not determined22760206084013384Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse

Markers in Region
Gsn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37235,139,442 - 35,139,507UniSTSGRCm37
Celera234,978,595 - 34,978,660UniSTS
Cytogenetic Map2BUniSTS
cM Map224.5UniSTS
cM Map224.5UniSTS
Gsn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38235,283,922 - 35,283,987UniSTSGRCm38
MGSCv37235,139,442 - 35,139,507UniSTSGRCm37
Celera234,978,595 - 34,978,660UniSTS
Cytogenetic Map2BUniSTS
Gsn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2BUniSTS
cM Map224.5UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001206367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_146120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK076156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL773523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY064133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY144206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY195027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY655071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN701174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000028239   ⟹   ENSMUSP00000028239
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl235,172,392 - 35,197,904 (+)Ensembl
GRCm38.p6 Ensembl235,282,380 - 35,307,892 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124323
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl235,172,525 - 35,175,037 (+)Ensembl
GRCm38.p6 Ensembl235,282,513 - 35,285,025 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139867   ⟹   ENSMUSP00000144217
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl235,146,461 - 35,180,459 (+)Ensembl
GRCm38.p6 Ensembl235,256,449 - 35,290,447 (+)Ensembl
Ensembl Acc Id: ENSMUST00000142324   ⟹   ENSMUSP00000118120
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl235,146,421 - 35,183,579 (+)Ensembl
GRCm38.p6 Ensembl235,256,409 - 35,293,567 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201185   ⟹   ENSMUSP00000144561
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl235,146,392 - 35,197,902 (+)Ensembl
GRCm38.p6 Ensembl235,256,380 - 35,307,890 (+)Ensembl
Ensembl Acc Id: ENSMUST00000202899   ⟹   ENSMUSP00000144470
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl235,146,408 - 35,183,581 (+)Ensembl
GRCm38.p6 Ensembl235,256,396 - 35,293,569 (+)Ensembl
Ensembl Acc Id: ENSMUST00000202990   ⟹   ENSMUSP00000144296
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl235,146,396 - 35,193,263 (+)Ensembl
GRCm38.p6 Ensembl235,256,384 - 35,303,251 (+)Ensembl
RefSeq Acc Id: NM_001206367   ⟹   NP_001193296
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)ENTREZGENE
Celera234,951,052 - 35,002,623 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001206368   ⟹   NP_001193297
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)ENTREZGENE
Celera234,951,052 - 35,002,623 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001206369   ⟹   NP_001193298
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,156,756 - 35,197,914 (+)NCBI
GRCm38235,266,744 - 35,307,902 (+)NCBI
Celera234,951,052 - 35,002,623 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001362945   ⟹   NP_001349874
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001362947   ⟹   NP_001349876
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001362948   ⟹   NP_001349877
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,146,371 - 35,197,914 (+)NCBI
GRCm38235,256,359 - 35,307,902 (+)NCBI
Sequence:
RefSeq Acc Id: NM_146120   ⟹   NP_666232
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,172,392 - 35,197,914 (+)NCBI
GRCm38235,282,380 - 35,307,902 (+)NCBI
MGSCv37235,137,960 - 35,163,412 (+)RGD
Celera234,951,052 - 35,002,623 (+)ENTREZGENE
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006497990   ⟹   XP_006498053
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39235,172,406 - 35,197,909 (+)NCBI
GRCm38235,282,389 - 35,307,897 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001193296 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193297 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193298 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349874 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349876 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349877 (Get FASTA)   NCBI Sequence Viewer  
  NP_666232 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498053 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37677 (Get FASTA)   NCBI Sequence Viewer  
  AAH23143 (Get FASTA)   NCBI Sequence Viewer  
  AAH60377 (Get FASTA)   NCBI Sequence Viewer  
  BAC36223 (Get FASTA)   NCBI Sequence Viewer  
  BAC41004 (Get FASTA)   NCBI Sequence Viewer  
  BAE25485 (Get FASTA)   NCBI Sequence Viewer  
  BAE27574 (Get FASTA)   NCBI Sequence Viewer  
  BAE28702 (Get FASTA)   NCBI Sequence Viewer  
  BAE29494 (Get FASTA)   NCBI Sequence Viewer  
  BAE30608 (Get FASTA)   NCBI Sequence Viewer  
  BAE31661 (Get FASTA)   NCBI Sequence Viewer  
  BAE39054 (Get FASTA)   NCBI Sequence Viewer  
  BAE39126 (Get FASTA)   NCBI Sequence Viewer  
  BAE39925 (Get FASTA)   NCBI Sequence Viewer  
  BAE40358 (Get FASTA)   NCBI Sequence Viewer  
  BAE40410 (Get FASTA)   NCBI Sequence Viewer  
  BAE40549 (Get FASTA)   NCBI Sequence Viewer  
  BAE40566 (Get FASTA)   NCBI Sequence Viewer  
  BAE40830 (Get FASTA)   NCBI Sequence Viewer  
  BAE41291 (Get FASTA)   NCBI Sequence Viewer  
  EDL08646 (Get FASTA)   NCBI Sequence Viewer  
  EDL08647 (Get FASTA)   NCBI Sequence Viewer  
  EDL08648 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000028239
  ENSMUSP00000028239.7
  ENSMUSP00000118120.2
  ENSMUSP00000144217.2
  ENSMUSP00000144296.2
  ENSMUSP00000144470.2
  ENSMUSP00000144561
  ENSMUSP00000144561.2
GenBank Protein P13020 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_666232   ⟸   NM_146120
- Peptide Label: isoform 1 precursor
- UniProtKB: Q8R590 (UniProtKB/Swiss-Prot),   Q3UPB1 (UniProtKB/Swiss-Prot),   P13020 (UniProtKB/Swiss-Prot),   Q3U9Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193296   ⟸   NM_001206367
- Peptide Label: isoform 2
- UniProtKB: Q3U9Q8 (UniProtKB/TrEMBL),   Q6PAC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193297   ⟸   NM_001206368
- Peptide Label: isoform 2
- UniProtKB: Q3U9Q8 (UniProtKB/TrEMBL),   Q6PAC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193298   ⟸   NM_001206369
- Peptide Label: isoform 2
- UniProtKB: Q3U9Q8 (UniProtKB/TrEMBL),   Q6PAC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498053   ⟸   XM_006497990
- Peptide Label: isoform X1
- UniProtKB: Q3U9Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001349874   ⟸   NM_001362945
- Peptide Label: isoform 3
- UniProtKB: Q3U9Q8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001349876   ⟸   NM_001362947
- Peptide Label: isoform 3
- UniProtKB: Q3U9Q8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001349877   ⟸   NM_001362948
- Peptide Label: isoform 2
- UniProtKB: Q3U9Q8 (UniProtKB/TrEMBL),   Q6PAC1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000144217   ⟸   ENSMUST00000139867
Ensembl Acc Id: ENSMUSP00000144470   ⟸   ENSMUST00000202899
Ensembl Acc Id: ENSMUSP00000144296   ⟸   ENSMUST00000202990
Ensembl Acc Id: ENSMUSP00000028239   ⟸   ENSMUST00000028239
Ensembl Acc Id: ENSMUSP00000118120   ⟸   ENSMUST00000142324
Ensembl Acc Id: ENSMUSP00000144561   ⟸   ENSMUST00000201185
Protein Domains
Gelsolin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P13020-F1-model_v2 AlphaFold P13020 1-780 view protein structure

Promoters
RGD ID:6831547
Promoter ID:MM_KWN:28883
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   MEF_B6
Transcripts:OTTMUST00000030969
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36235,134,221 - 35,135,247 (+)MPROMDB
RGD ID:6831546
Promoter ID:MM_KWN:28884
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung,   MEF_B6
Transcripts:OTTMUST00000028765,   OTTMUST00000030967,   OTTMUST00000030968
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36235,137,391 - 35,137,927 (+)MPROMDB
RGD ID:6847659
Promoter ID:MM_ACW:28092
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   Lung,   MEF_B6
Transcripts:GSN.HSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36235,157,751 - 35,158,277 (+)MPROMDB
RGD ID:6847656
Promoter ID:MM_ACW:28093
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:GSN.KSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36235,159,826 - 35,160,326 (+)MPROMDB
RGD ID:6877124
Promoter ID:EPDNEW_M2013
Type:initiation region
Name:Gsn_1
Description:Mus musculus gelsolin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2014  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38235,256,422 - 35,256,482EPDNEW
RGD ID:6877126
Promoter ID:EPDNEW_M2014
Type:initiation region
Name:Gsn_2
Description:Mus musculus gelsolin , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2013  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38235,266,840 - 35,266,900EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95851 AgrOrtholog
Ensembl Genes ENSMUSG00000026879 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000028239 ENTREZGENE
  ENSMUST00000028239.8 UniProtKB/Swiss-Prot
  ENSMUST00000139867.5 UniProtKB/TrEMBL
  ENSMUST00000142324.8 UniProtKB/TrEMBL
  ENSMUST00000201185 ENTREZGENE
  ENSMUST00000201185.4 UniProtKB/Swiss-Prot
  ENSMUST00000202899.4 UniProtKB/TrEMBL
  ENSMUST00000202990.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gelsolin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Villin/Gelsolin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:227753 UniProtKB/Swiss-Prot
MGD MGI:95851 ENTREZGENE
NCBI Gene Gsn ENTREZGENE
PANTHER GELSOLIN UniProtKB/Swiss-Prot
  PTHR11977 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11977:SF29 UniProtKB/TrEMBL
Pfam Gelsolin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gsn PhenoGen
PRINTS GELSOLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0J9YUJ8_MOUSE UniProtKB/TrEMBL
  A0A0J9YUQ8_MOUSE UniProtKB/TrEMBL
  A6PWS5_MOUSE UniProtKB/TrEMBL
  GELS_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TGJ9_MOUSE UniProtKB/TrEMBL
  Q3U9Q8 ENTREZGENE, UniProtKB/TrEMBL
  Q3UCW8_MOUSE UniProtKB/TrEMBL
  Q3UPB1 ENTREZGENE
  Q6PAC1 ENTREZGENE, UniProtKB/TrEMBL
  Q8R590 ENTREZGENE
UniProt Secondary A0A0J9YV37 UniProtKB/TrEMBL
  Q3UPB1 UniProtKB/Swiss-Prot
  Q8R590 UniProtKB/Swiss-Prot