Nxn (nucleoredoxin) - Rat Genome Database

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Gene: Nxn (nucleoredoxin) Mus musculus
Analyze
Symbol: Nxn
Name: nucleoredoxin
RGD ID: 1321420
MGI Page MGI
Description: Enables thioredoxin-disulfide reductase (NADPH) activity. Involved in circulatory system development; negative regulation of Wnt signaling pathway; and negative regulation of protein ubiquitination. Acts upstream of or within in utero embryonic development. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; musculoskeletal system; and nervous system. Human ortholog(s) of this gene implicated in autosomal recessive Robinow syndrome 2. Orthologous to human NXN (nucleoredoxin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: l11Jus; l11Jus13; protein Red-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,148,052 - 76,289,967 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1176,148,024 - 76,289,966 (-)EnsemblGRCm39 Ensembl
GRCm381176,257,226 - 76,399,141 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,257,198 - 76,399,140 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,070,728 - 76,212,643 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,074,153 - 76,215,336 (-)NCBIMGSCv36mm8
Celera1183,770,072 - 83,910,908 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(E,E)-2,4-hexadienal  (ISO)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methylcholanthrene  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcium dichloride  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
chrysene  (EXP)
cisplatin  (EXP)
clobetasol  (EXP)
clofibrate  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (EXP)
ethanol  (EXP)
Evodiamine  (EXP)
folic acid  (EXP)
fonofos  (ISO)
fulvestrant  (ISO)
indole-3-methanol  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
lutein  (EXP)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
Soman  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
trovafloxacin  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
nucleus  (IBA,IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cell physiology  (IAGP)
abnormal craniofacial morphology  (IEA)
abnormal cranium morphology  (IEA)
abnormal digit morphology  (IEA)
abnormal embryo size  (IEA)
abnormal eyelid morphology  (IEA)
abnormal facial morphology  (IEA)
abnormal freezing behavior  (IEA)
abnormal head shape  (IEA)
abnormal head size  (IEA)
abnormal locomotor behavior  (IEA)
abnormal mammary gland morphology  (IEA)
abnormal Mullerian duct morphology  (IEA)
abnormal optic disk morphology  (IEA)
abnormal retina blood vessel morphology  (IEA)
abnormal snout morphology  (IEA)
abnormal sternum morphology  (IAGP)
abnormal vitelline vein topology  (IEA)
absent stapedial artery  (IEA)
anophthalmia  (IEA)
atrioventricular septal defect  (IAGP)
cleft palate  (IEA)
decreased body length  (IEA)
decreased cardiac muscle contractility  (IEA)
decreased exploration in new environment  (IEA)
decreased fetal size  (IAGP)
decreased intestine length  (IEA)
decreased locomotor activity  (IEA)
dilated liver sinusoidal space  (IEA)
double outlet right ventricle  (IEA)
facial cleft  (IEA)
hemorrhage  (IEA)
herniated liver  (IEA)
increased circulating alkaline phosphatase level  (IEA)
increased circulating bilirubin level  (IEA)
increased circulating HDL cholesterol level  (IEA)
increased circulating triglyceride level  (IEA)
increased effector memory CD8-positive, alpha-beta T cell number  (IEA)
increased fasting circulating glucose level  (IEA)
increased grip strength  (IEA)
increased mean corpuscular hemoglobin concentration  (IEA)
increased osteoblast cell number  (IAGP)
irregularly shaped pupil  (IEA)
no spontaneous movement  (IEA)
perimembraneous ventricular septal defect  (IEA)
perinatal lethality, complete penetrance  (IAGP)
persistent truncus arteriosus  (IAGP)
preweaning lethality, complete penetrance  (IEA)
preweaning lethality, incomplete penetrance  (IEA)
short tibia  (IEA)
small adrenal glands  (IEA)
small frontal bone  (IAGP)
spina bifida  (IEA)
split xiphoid process  (IAGP)
unresponsive to tactile stimuli  (IEA)
ventricular septal defect  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9119370   PMID:10349636   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12955145   PMID:14610273   PMID:15670764   PMID:15782199  
PMID:15840001   PMID:16141072   PMID:16141073   PMID:16466971   PMID:16604061   PMID:16764867   PMID:17967808   PMID:18691226   PMID:18799693   PMID:19643732   PMID:19906978   PMID:20011118  
PMID:20400501   PMID:20970343   PMID:21251912   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23109420   PMID:24120946   PMID:24194600   PMID:24457600   PMID:27626380   PMID:27996060  
PMID:28185240   PMID:28700664   PMID:29539633   PMID:30157441   PMID:30973865   PMID:32325033   PMID:34198070   PMID:34321999   PMID:36126861   PMID:38355793   PMID:38822427  


Genomics

Comparative Map Data
Nxn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,148,052 - 76,289,967 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1176,148,024 - 76,289,966 (-)EnsemblGRCm39 Ensembl
GRCm381176,257,226 - 76,399,141 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,257,198 - 76,399,140 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,070,728 - 76,212,643 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,074,153 - 76,215,336 (-)NCBIMGSCv36mm8
Celera1183,770,072 - 83,910,908 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
NXN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3817799,310 - 979,776 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl17799,310 - 979,776 (-)EnsemblGRCh38hg38GRCh38
GRCh3717702,550 - 883,016 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3617649,335 - 829,760 (-)NCBINCBI36Build 36hg18NCBI36
Build 3417649,334 - 829,760NCBI
Celera17714,726 - 894,595 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef17612,981 - 789,470 (-)NCBIHuRef
CHM1_117711,357 - 891,770 (-)NCBICHM1_1
T2T-CHM13v2.017685,572 - 866,169 (-)NCBIT2T-CHM13v2.0
Nxn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81061,607,557 - 61,745,807 (-)NCBIGRCr8
mRatBN7.21061,109,322 - 61,247,578 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1061,110,020 - 61,248,251 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1065,751,867 - 65,893,235 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01065,257,315 - 65,398,693 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01060,727,671 - 60,868,987 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01064,411,710 - 64,550,147 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1064,412,833 - 64,550,145 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01063,464,225 - 63,602,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41067,775,938 - 67,913,018 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11067,789,548 - 67,927,072 (+)NCBI
Celera1060,125,836 - 60,262,704 (-)NCBICelera
Cytogenetic Map10q24NCBI
Nxn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554812,338,445 - 2,481,557 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554812,338,005 - 2,481,557 (-)NCBIChiLan1.0ChiLan1.0
NXN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,348,844 - 8,533,378 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11710,320,098 - 10,504,511 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v017769,179 - 946,981 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.117690,089 - 720,659 (-)NCBIpanpan1.1PanPan1.1panPan2
NXN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1944,847,468 - 45,003,129 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl944,847,558 - 44,998,906 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha943,998,054 - 44,150,808 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0945,664,165 - 45,818,376 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl945,664,254 - 45,816,996 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1944,443,986 - 44,597,122 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0944,729,843 - 44,890,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0944,816,642 - 44,969,467 (+)NCBIUU_Cfam_GSD_1.0
Nxn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,010,042 - 44,116,920 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365386,966,296 - 6,995,691 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NXN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1246,904,407 - 47,075,432 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11246,909,175 - 47,075,435 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21249,205,888 - 49,239,692 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NXN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116543,375 - 717,671 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605921,373,073 - 21,542,511 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nxn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247863,372,796 - 3,515,142 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247863,373,533 - 3,516,592 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nxn
4121 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1066
Count of miRNA genes:511
Interacting mature miRNAs:621
Transcripts:ENSMUST00000021204, ENSMUST00000131472
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse

Markers in Region
D11Jcs11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,322,793 - 76,323,041UniSTSGRCm38
MGSCv371176,136,295 - 76,136,543UniSTSGRCm37
Celera1183,835,127 - 83,835,359UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.0UniSTS
UniSTS:236643  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,396,773 - 76,397,042UniSTSGRCm38
MGSCv371176,210,275 - 76,210,544UniSTSGRCm37
Celera1183,908,569 - 83,908,838UniSTS
Cytogenetic Map11B5UniSTS
cM Map1145.2UniSTS
UniSTS:236647  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,257,785 - 76,257,877UniSTSGRCm38
MGSCv371176,071,287 - 76,071,379UniSTSGRCm37
Celera1183,770,631 - 83,770,723UniSTS
Cytogenetic Map11B5UniSTS
cM Map1145.2UniSTS
D11Bhm34  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,260,950 - 76,261,060UniSTSGRCm38
MGSCv371176,074,452 - 76,074,562UniSTSGRCm37
Celera1183,773,801 - 83,773,911UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.58UniSTS
D11Bhm35  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,275,517 - 76,275,633UniSTSGRCm38
MGSCv371176,089,019 - 76,089,135UniSTSGRCm37
Celera1183,788,271 - 83,788,387UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.61UniSTS
D11Bhm36  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,297,364 - 76,297,527UniSTSGRCm38
MGSCv371176,110,866 - 76,111,029UniSTSGRCm37
Celera1183,809,858 - 83,810,021UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.64UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB095441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB095442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB095443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB095444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB096016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB096017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB096018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB096019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI425633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL663050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL806529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X92750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000021204   ⟹   ENSMUSP00000021204
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,148,024 - 76,289,966 (-)Ensembl
GRCm38.p6 Ensembl1176,257,198 - 76,399,140 (-)Ensembl
Ensembl Acc Id: ENSMUST00000131472
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,249,629 - 76,289,894 (-)Ensembl
GRCm38.p6 Ensembl1176,358,803 - 76,399,068 (-)Ensembl
RefSeq Acc Id: NM_008750   ⟹   NP_032776
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,148,052 - 76,289,967 (-)NCBI
GRCm381176,257,226 - 76,399,141 (-)ENTREZGENE
MGSCv371176,070,728 - 76,212,643 (-)RGD
Celera1183,770,072 - 83,910,908 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032776   ⟸   NM_008750
- UniProtKB: P97346 (UniProtKB/Swiss-Prot),   Q5H8U0 (UniProtKB/Swiss-Prot),   Q5H8T6 (UniProtKB/Swiss-Prot),   Q99KF3 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000021204   ⟸   ENSMUST00000021204
Protein Domains
Thioredoxin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97346-F1-model_v2 AlphaFold P97346 1-435 view protein structure

Promoters
RGD ID:6821475
Promoter ID:MM_KWN:8560
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000014069,   UC007KFP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361176,212,471 - 76,212,971 (-)MPROMDB
RGD ID:8675596
Promoter ID:EPDNEW_M15829
Type:initiation region
Name:Nxn_1
Description:Mus musculus nucleoredoxin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381176,399,133 - 76,399,193EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109331 AgrOrtholog
Ensembl Genes ENSMUSG00000020844 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000021204 ENTREZGENE
  ENSMUST00000021204.4 UniProtKB/Swiss-Prot
Gene3D-CATH Glutaredoxin UniProtKB/Swiss-Prot
InterPro NRX_PDI_b' UniProtKB/Swiss-Prot
  Thioredoxin-like_fold UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
  Thioredoxin_domain UniProtKB/Swiss-Prot
  TryX_NRX_thioredoxin_dom UniProtKB/Swiss-Prot
KEGG Report mmu:18230 UniProtKB/Swiss-Prot
MGD MGI:109331 ENTREZGENE
NCBI Gene 18230 ENTREZGENE
PANTHER NUCLEOREDOXIN UniProtKB/Swiss-Prot
  NUCLEOREDOXIN UniProtKB/Swiss-Prot
Pfam Thioredoxin_6 UniProtKB/Swiss-Prot
  Thioredoxin_8 UniProtKB/Swiss-Prot
PhenoGen Nxn PhenoGen
PROSITE THIOREDOXIN_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot
UniProt NXN_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5H8T6 ENTREZGENE
  Q5H8U0 ENTREZGENE
  Q99KF3 ENTREZGENE
UniProt Secondary Q5H8T6 UniProtKB/Swiss-Prot
  Q5H8U0 UniProtKB/Swiss-Prot
  Q99KF3 UniProtKB/Swiss-Prot