Arhgap44 (Rho GTPase activating protein 44) - Rat Genome Database

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Gene: Arhgap44 (Rho GTPase activating protein 44) Mus musculus
Analyze
Symbol: Arhgap44
Name: Rho GTPase activating protein 44
RGD ID: 1332239
MGI Page MGI
Description: Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including negative regulation of Rac protein signal transduction; regulation of dendritic spine morphogenesis; and regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane. Located in dendritic spine. Is active in glutamatergic synapse. Is expressed in central nervous system; olfactory epithelium; respiratory system; and retina. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and skin melanoma. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6330543G20; AI840762; AU04082; AW493732; rho GTPase-activating protein 44; rho GTPase-activating protein RICH2; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2; RICH-2; Rich2; RP23-219K7.2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391164,892,865 - 65,053,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1164,892,865 - 65,053,787 (-)EnsemblGRCm39 Ensembl
GRCm381165,002,039 - 65,162,972 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,002,039 - 65,162,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv371164,815,541 - 64,976,463 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361164,818,234 - 64,979,156 (-)NCBIMGSCv36mm8
Celera1171,938,015 - 72,099,074 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Screening low-frequency SNPS from genome-wide association study reveals a new risk allele for progression to AIDS. Le Clerc S, etal., J Acquir Immune Defic Syndr. 2011 Mar 1;56(3):279-84. doi: 10.1097/QAI.0b013e318204982b.
2. Genetic variants in the genes encoding rho GTPases and related regulators predict cutaneous melanoma-specific survival. Liu S, etal., Int J Cancer. 2017 Aug 15;141(4):721-730. doi: 10.1002/ijc.30785. Epub 2017 Jun 1.
3. A comprehensive landscape of transcription profiles and data resources for human leukemia. Luo M, etal., Blood Adv. 2023 Jul 25;7(14):3435-3449. doi: 10.1182/bloodadvances.2022008410.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. RICH2 is implicated in viraemic control of HIV-1 in black South African individuals. Paximadis M, etal., Infect Genet Evol. 2017 Apr;49:78-87. doi: 10.1016/j.meegid.2017.01.007. Epub 2017 Jan 6.
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Mutant p53 promotes cell spreading and migration via ARHGAP44. Xu J, etal., Sci China Life Sci. 2017 Sep;60(9):1019-1029. doi: 10.1007/s11427-016-9040-8. Epub 2017 May 16.
9. RICH2, a potential tumor suppressor in hepatocellular carcinoma. Zhang J, etal., Front Biosci (Landmark Ed). 2019 Jun 1;24(8):1363-1376. doi: 10.2741/4784.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:11431473   PMID:12466851   PMID:12477932   PMID:12520002   PMID:14610273  
PMID:15489334   PMID:16141072   PMID:16141073   PMID:16512683   PMID:16602821   PMID:21267068   PMID:21873635   PMID:23739967   PMID:24352656   PMID:26969129   PMID:28642683   PMID:28671696  
PMID:32325033   PMID:37142655   PMID:37926169   PMID:38355793  


Genomics

Comparative Map Data
Arhgap44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391164,892,865 - 65,053,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1164,892,865 - 65,053,787 (-)EnsemblGRCm39 Ensembl
GRCm381165,002,039 - 65,162,972 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,002,039 - 65,162,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv371164,815,541 - 64,976,463 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361164,818,234 - 64,979,156 (-)NCBIMGSCv36mm8
Celera1171,938,015 - 72,099,074 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.42NCBI
ARHGAP44
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381712,789,498 - 12,991,643 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1712,789,498 - 12,991,643 (+)EnsemblGRCh38hg38GRCh38
GRCh371712,692,815 - 12,894,960 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361712,633,554 - 12,835,685 (+)NCBINCBI36Build 36hg18NCBI36
Celera1712,718,166 - 12,920,275 (+)NCBICelera
Cytogenetic Map17p12NCBI
HuRef1712,588,245 - 12,790,668 (+)NCBIHuRef
CHM1_11712,701,589 - 12,903,719 (+)NCBICHM1_1
T2T-CHM13v2.01712,696,985 - 12,899,110 (+)NCBIT2T-CHM13v2.0
Arhgap44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81050,154,724 - 50,322,027 (-)NCBIGRCr8
mRatBN7.21049,655,583 - 49,822,876 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1049,655,584 - 49,824,297 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01051,501,547 - 51,669,546 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1051,502,894 - 51,669,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01051,259,533 - 51,425,933 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41051,313,035 - 51,479,556 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11051,328,436 - 51,494,957 (-)NCBI
Celera1048,871,532 - 49,038,827 (-)NCBICelera
Cytogenetic Map10q24NCBI
Arhgap44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554674,430,087 - 4,522,611 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554674,428,738 - 4,590,877 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP44
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21960,757,445 - 60,959,269 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11765,564,061 - 65,765,878 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01738,657,824 - 38,859,591 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11743,357,438 - 43,558,355 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1743,357,438 - 43,453,457 (-)Ensemblpanpan1.1panPan2
ARHGAP44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1536,790,059 - 36,957,932 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl536,789,814 - 36,957,411 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha536,933,812 - 37,101,416 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0536,898,675 - 37,066,421 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl536,898,649 - 37,066,421 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1536,871,586 - 37,039,378 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0536,818,449 - 36,986,578 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0537,008,878 - 37,176,525 (+)NCBIUU_Cfam_GSD_1.0
Arhgap44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560251,899,406 - 52,068,726 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365955,373,476 - 5,543,073 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365955,373,645 - 5,542,915 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1257,049,895 - 57,206,889 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11257,049,900 - 57,206,706 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21260,167,786 - 60,195,211 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11612,125,543 - 12,328,203 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1612,125,574 - 12,330,501 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660598,910,762 - 9,113,230 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap44
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624877661,998 - 850,431 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624877662,595 - 851,762 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgap44
6351 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2558
Count of miRNA genes:625
Interacting mature miRNAs:776
Transcripts:ENSMUST00000047463, ENSMUST00000093001, ENSMUST00000093002, ENSMUST00000130420
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115925661769482699Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115406567067078411Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
4141642Ltxs2_mlethal factor toxin susceptibility 2 (mouse)Not determined116304211368500330Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115408094165103841Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
AI840762  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,021,796 - 65,021,897UniSTSGRCm38
MGSCv371164,835,298 - 64,835,399UniSTSGRCm37
Celera1171,957,772 - 71,957,873UniSTS
Cytogenetic Map11B3UniSTS
Whitehead/MRC_RH11851.8UniSTS
AU040829  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,002,124 - 65,002,233UniSTSGRCm38
MGSCv371164,815,626 - 64,815,735UniSTSGRCm37
Celera1171,938,100 - 71,938,209UniSTS
Cytogenetic Map11B3UniSTS
cM Map1131.0UniSTS
Whitehead/MRC_RH11851.05UniSTS
Whitehead/MRC_RH11852.61UniSTS
RH124888  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,001,737 - 65,001,853UniSTSGRCm38
MGSCv371164,815,239 - 64,815,355UniSTSGRCm37
Celera1171,937,713 - 71,937,829UniSTS
Cytogenetic Map11B3UniSTS
cM Map1131.0UniSTS
UniSTS:236614  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,002,164 - 65,002,392UniSTSGRCm38
MGSCv371164,815,666 - 64,815,894UniSTSGRCm37
Celera1171,938,140 - 71,938,368UniSTS
Cytogenetic Map11B3UniSTS
cM Map1131.0UniSTS
RH138269  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,151,957 - 65,152,084UniSTSGRCm38
MGSCv371164,965,459 - 64,965,586UniSTSGRCm37
Celera1172,087,982 - 72,088,109UniSTS
Cytogenetic Map11B3UniSTS
UniSTS:224505  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,013,818 - 65,013,975UniSTSGRCm38
MGSCv371164,827,320 - 64,827,477UniSTSGRCm37
Celera1171,949,794 - 71,949,951UniSTS
Cytogenetic Map11B3UniSTS
RH125885  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,001,801 - 65,002,052UniSTSGRCm38
MGSCv371164,815,303 - 64,815,554UniSTSGRCm37
Celera1171,937,777 - 71,938,028UniSTS
Cytogenetic Map11B3UniSTS
cM Map1131.0UniSTS
Whitehead/MRC_RH11848.76UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001099288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK032008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL663045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ059392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000047463   ⟹   ENSMUSP00000039139
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1164,892,865 - 65,053,787 (-)Ensembl
GRCm38.p6 Ensembl1165,002,039 - 65,162,961 (-)Ensembl
Ensembl Acc Id: ENSMUST00000093001   ⟹   ENSMUSP00000090680
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1164,942,301 - 65,053,393 (-)Ensembl
GRCm38.p6 Ensembl1165,051,475 - 65,162,567 (-)Ensembl
Ensembl Acc Id: ENSMUST00000093002   ⟹   ENSMUSP00000090681
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1164,892,866 - 65,053,730 (-)Ensembl
GRCm38.p6 Ensembl1165,002,040 - 65,162,904 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130420   ⟹   ENSMUSP00000115612
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1164,892,867 - 64,950,660 (-)Ensembl
GRCm38.p6 Ensembl1165,002,041 - 65,059,834 (-)Ensembl
RefSeq Acc Id: NM_001099288   ⟹   NP_001092758
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
GRCm381165,002,039 - 65,162,961 (-)NCBI
MGSCv371164,815,541 - 64,976,463 (-)RGD
Celera1171,938,015 - 72,099,074 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001408223   ⟹   NP_001395152
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
RefSeq Acc Id: NM_001408224   ⟹   NP_001395153
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
RefSeq Acc Id: NM_001408226   ⟹   NP_001395155
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
RefSeq Acc Id: NM_001408228   ⟹   NP_001395157
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
RefSeq Acc Id: NM_175003   ⟹   NP_778168
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
GRCm381165,002,039 - 65,162,961 (-)NCBI
MGSCv371164,815,541 - 64,976,463 (-)RGD
Celera1171,938,015 - 72,099,074 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532874   ⟹   XP_006532937
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,871 - 64,957,313 (-)NCBI
GRCm381165,002,039 - 65,066,514 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245812   ⟹   XP_030101672
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,871 - 65,053,104 (-)NCBI
GRCm381165,002,039 - 65,162,278 (-)NCBI
Sequence:
RefSeq Acc Id: NP_778168   ⟸   NM_175003
- Peptide Label: isoform 2
- UniProtKB: F6T1Y2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001092758   ⟸   NM_001099288
- Peptide Label: isoform 1
- UniProtKB: Q5SSM3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532937   ⟸   XM_006532874
- Peptide Label: isoform X4
- UniProtKB: F6T1Y2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101672   ⟸   XM_030245812
- Peptide Label: isoform X4
- UniProtKB: F6T1Y2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000115612   ⟸   ENSMUST00000130420
Ensembl Acc Id: ENSMUSP00000090681   ⟸   ENSMUST00000093002
Ensembl Acc Id: ENSMUSP00000090680   ⟸   ENSMUST00000093001
Ensembl Acc Id: ENSMUSP00000039139   ⟸   ENSMUST00000047463
RefSeq Acc Id: NP_001395155   ⟸   NM_001408226
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001395157   ⟸   NM_001408228
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001395152   ⟸   NM_001408223
- Peptide Label: isoform 3
- UniProtKB: Q7TNB9 (UniProtKB/Swiss-Prot),   Q5SSM7 (UniProtKB/Swiss-Prot),   Q5SSM6 (UniProtKB/Swiss-Prot),   Q5SSM4 (UniProtKB/Swiss-Prot),   Q5SSM3 (UniProtKB/Swiss-Prot),   Q8BW90 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001395153   ⟸   NM_001408224
- Peptide Label: isoform 4
Protein Domains
BAR   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5SSM3-F1-model_v2 AlphaFold Q5SSM3 1-814 view protein structure

Promoters
RGD ID:6820474
Promoter ID:MM_KWN:7892
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000093002,   ENSMUST00000093003,   NM_001099288,   NM_175003,   OTTMUST00000013122
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361164,976,076 - 64,976,576 (-)MPROMDB
RGD ID:8675036
Promoter ID:EPDNEW_M15549
Type:initiation region
Name:Arhgap44_1
Description:Mus musculus Rho GTPase activating protein 44 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381165,162,937 - 65,162,997EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2144423 AgrOrtholog
Ensembl Genes ENSMUSG00000033389 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047463 ENTREZGENE
  ENSMUST00000047463.15 UniProtKB/Swiss-Prot
  ENSMUST00000093001.5 UniProtKB/Swiss-Prot
  ENSMUST00000093002 ENTREZGENE
  ENSMUST00000093002.12 UniProtKB/Swiss-Prot
  ENSMUST00000130420 ENTREZGENE
  ENSMUST00000130420.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.1270.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHG17/44/SH3BP1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:216831 UniProtKB/Swiss-Prot
MGD MGI:2144423 ENTREZGENE
NCBI Gene Arhgap44 ENTREZGENE
PANTHER 3BP-1 RELATED RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 44 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arhgap44 PhenoGen
PROSITE BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BAR UniProtKB/Swiss-Prot
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt F6T1Y2 ENTREZGENE, UniProtKB/TrEMBL
  Q5SSM3 ENTREZGENE
  Q5SSM4 ENTREZGENE
  Q5SSM6 ENTREZGENE
  Q5SSM7 ENTREZGENE
  Q7TNB9 ENTREZGENE
  Q8BW90 ENTREZGENE
  Q8C090_MOUSE UniProtKB/TrEMBL
  RHG44_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q5SSM4 UniProtKB/Swiss-Prot
  Q5SSM6 UniProtKB/Swiss-Prot
  Q5SSM7 UniProtKB/Swiss-Prot
  Q7TNB9 UniProtKB/Swiss-Prot
  Q8BW90 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Arhgap44  Rho GTPase activating protein 44  AU040829  expressed sequence AU040829  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 AU040829  expressed sequence AU040829  Arhgap44  Rho GTPase activating protein 44  Symbol and/or name change 5135510 APPROVED
2011-07-27 Arhgap44  Rho GTPase activating protein 44  AU040829  expressed sequence AU040829  Symbol and/or name change 5135510 APPROVED