Arhgap44 (Rho GTPase activating protein 44) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Arhgap44 (Rho GTPase activating protein 44) Mus musculus
Analyze
Symbol: Arhgap44
Name: Rho GTPase activating protein 44
RGD ID: 1332239
MGI Page MGI
Description: Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including negative regulation of Rac protein signal transduction; regulation of dendritic spine morphogenesis; and regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane. Located in dendritic spine. Is active in glutamatergic synapse. Is expressed in central nervous system; olfactory epithelium; respiratory system; and retina. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and skin melanoma. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6330543G20; AI840762; AU04082; AW493732; rho GTPase-activating protein 44; rho GTPase-activating protein RICH2; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2; RICH-2; Rich2; RP23-219K7.2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391164,892,865 - 65,053,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1164,892,865 - 65,053,787 (-)EnsemblGRCm39 Ensembl
GRCm381165,002,039 - 65,162,972 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,002,039 - 65,162,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv371164,815,541 - 64,976,463 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361164,818,234 - 64,979,156 (-)NCBIMGSCv36mm8
Celera1171,938,015 - 72,099,074 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Arhgap44Mouseacquired immunodeficiency syndrome disease_progressionISOARHGAP44 (Homo sapiens)401901288DNA:SNPs more ...RGD 
Arhgap44Mouseacquired immunodeficiency syndrome disease_progressionISOARHGAP44 (Homo sapiens)401901289DNA:SNP:intron: (rs2072255) (human)RGD 
Arhgap44Mousechronic lymphocytic leukemia  ISOARHGAP44 (Homo sapiens)401901275mRNA:increased expression: (human)RGD 
Arhgap44Mousehepatocellular carcinoma exacerbatesISOARHGAP44 (Homo sapiens)401901276protein:decreased expression:liver (human)RGD 
Arhgap44Mouselung adenocarcinoma  ISOARHGAP44 (Homo sapiens)401901290mRNA:decreased expression:lung (human)RGD 
Arhgap44Mouselung carcinoma  ISOARHGAP44 (Homo sapiens)401901290mRNA:decreased expression:lung (human)RGD 
Arhgap44Mouselung large cell carcinoma  ISOARHGAP44 (Homo sapiens)401901290mRNA:decreased expression:lung (human)RGD 
Arhgap44Mouselung squamous cell carcinoma  ISOARHGAP44 (Homo sapiens)401901290mRNA:decreased expression:lung (human)RGD 
Arhgap44Mouseskin melanoma severityISOARHGAP44 (Homo sapiens)401901274DNA:SNP:intron: (rs72635537) (human)RGD 
1 to 9 of 9 rows

1 to 20 of 49 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Arhgap44Mouse1,2-dimethylhydrazine increases expressionEXP 64804641 and 2-Dimethylhydrazine results in increased expression of ARHGAP44 mRNACTDPMID:22206623
Arhgap44Mouse1,3-dinitrobenzene decreases expressionISOArhgap44 (Rattus norvegicus)64804643-dinitrobenzene results in decreased expression of ARHGAP44 mRNACTDPMID:21983209
Arhgap44Mouse17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of ARHGAP44 mRNACTDPMID:39298647
Arhgap44Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOARHGAP44 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of ARHGAP44 mRNACTDPMID:20106945
Arhgap44Mouse3-methylcholanthrene multiple interactionsISOARHGAP44 (Homo sapiens)6480464Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP44 promoter]CTDPMID:20348232
Arhgap44Mouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of ARHGAP44 mRNACTDPMID:39298647
Arhgap44Mouse4-hydroxyphenyl retinamide decreases expressionEXP 6480464Fenretinide results in decreased expression of ARHGAP44 mRNACTDPMID:28973697
Arhgap44Mouse4-hydroxyphenyl retinamide increases expressionEXP 6480464Fenretinide results in increased expression of ARHGAP44 mRNACTDPMID:28973697
Arhgap44Mouseaflatoxin B1 decreases expressionISOARHGAP44 (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of ARHGAP44 mRNACTDPMID:22100608
Arhgap44Mouseaflatoxin B1 increases methylationISOARHGAP44 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of ARHGAP44 intronCTDPMID:30157460
Arhgap44MouseAflatoxin B2 alpha increases methylationISOARHGAP44 (Homo sapiens)6480464aflatoxin B2 results in increased methylation of ARHGAP44 intronCTDPMID:30157460
Arhgap44Mousealpha-Zearalanol multiple interactionsISOArhgap44 (Rattus norvegicus)6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of ARHGAP44 mRNACTDPMID:35163327
Arhgap44Mousearistolochic acid A decreases expressionISOARHGAP44 (Homo sapiens)6480464aristolochic acid I results in decreased expression of ARHGAP44 mRNACTDPMID:33212167
Arhgap44Mouseatrazine affects methylationISOArhgap44 (Rattus norvegicus)6480464Atrazine affects the methylation of ARHGAP44 geneCTDPMID:35440735
Arhgap44Mousebenzo[a]pyrene decreases expressionISOARHGAP44 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of ARHGAP44 mRNACTDPMID:20106945 more ...
Arhgap44Mousebenzo[a]pyrene affects methylationISOARHGAP44 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of ARHGAP44 3' UTR and Benzo(a)pyrene affects the methylation of ARHGAP44 promoterCTDPMID:27901495
Arhgap44Mousebenzo[a]pyrene increases methylationISOARHGAP44 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of ARHGAP44 exonCTDPMID:27901495
Arhgap44Mousebenzo[a]pyrene diol epoxide I decreases expressionISOARHGAP44 (Homo sapiens)64804647 more ...CTDPMID:26238291
Arhgap44Mousebenzo[e]pyrene increases methylationISOARHGAP44 (Homo sapiens)6480464benzo(e)pyrene results in increased methylation of ARHGAP44 intronCTDPMID:30157460
Arhgap44Mousebisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of ARHGAP44 mRNACTDPMID:26063408

1 to 20 of 49 rows

Biological Process
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Arhgap44Mousemodification of postsynaptic structure involved_inIDA 2290270 PMID:23739967SynGOPMID:23739967
Arhgap44Mousemodulation of chemical synaptic transmission involved_inIDA 2290270 PMID:23739967SynGOPMID:23739967
Arhgap44Mousemodulation of chemical synaptic transmission involved_inIMP 2290270 PMID:23739967SynGOPMID:23739967
Arhgap44Mousenegative regulation of filopodium assembly  ISOArhgap44 (Rattus norvegicus)9068941 RGDPMID:25498153 and REF_RGD_ID:14402441
Arhgap44Mousenegative regulation of filopodium assembly involved_inISOArhgap44 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Arhgap44Mousenegative regulation of filopodium assembly involved_inISSUniProtKB:F1LQX42290270 UniProtGO_REF:0000024
Arhgap44Mousenegative regulation of Rac protein signal transduction involved_inIMP 2290270 PMID:24352656ARUK-UCLPMID:24352656
Arhgap44Mousenegative regulation of Rac protein signal transduction involved_inIBAPANTHER:PTN002680016 and MGI:21444232290270 GO_CentralGO_REF:0000033
Arhgap44Mouseregulation of actin cytoskeleton organization involved_inIBAPANTHER:PTN001797409 more ...2290270 GO_CentralGO_REF:0000033
Arhgap44Mouseregulation of dendritic spine morphogenesis involved_inIMP 2290270 PMID:24352656ARUK-UCLPMID:24352656
Arhgap44Mouseregulation of dendritic spine morphogenesis involved_inIBAPANTHER:PTN002680016 and MGI:21444232290270 GO_CentralGO_REF:0000033
Arhgap44Mouseregulation of neurotransmitter receptor transport, endosome to postsynaptic membrane involved_inIDA 2290270 PMID:23739967SynGOPMID:23739967
Arhgap44Mouseregulation of neurotransmitter receptor transport, endosome to postsynaptic membrane involved_inIMP 2290270 PMID:23739967SynGOPMID:23739967
Arhgap44Mousesignal transduction involved_inIEAInterPro:IPR0001982290270 InterProGO_REF:0000002
1 to 14 of 14 rows

Cellular Component
1 to 20 of 25 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Arhgap44Mousedendrite located_inISOArhgap44 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Arhgap44Mousedendrite located_inISSUniProtKB:F1LQX42290270 UniProtGO_REF:0000024
Arhgap44Mousedendrite  ISOArhgap44 (Rattus norvegicus)9068941MMO:0000686 immunofluorescence confocal microscopyRGDPMID:23739967 and REF_RGD_ID:12050108
Arhgap44Mousedendritic spine located_inIDA 2290270 PMID:24352656ARUK-UCLPMID:24352656
Arhgap44Mousedendritic spine is_active_inIBAPANTHER:PTN002680016 and MGI:21444232290270 GO_CentralGO_REF:0000033
Arhgap44Mouseglutamatergic synapse is_active_inISOArhgap44 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Arhgap44Mouseglutamatergic synapse is_active_inIDA 2290270 PMID:23739967SynGOPMID:23739967
Arhgap44Mouseglutamatergic synapse is_active_inIMP 2290270 PMID:23739967SynGOPMID:23739967
Arhgap44Mouseleading edge membrane located_inISOUniProtKB:Q17R892290270 GO_CentralGO_REF:0000119
Arhgap44Mouseleading edge membrane located_inIEAUniProtKB:Q17R89 and ensembl:ENSP000003689942290270 EnsemblGO_REF:0000107
Arhgap44Mouseleading edge membrane is_active_inIBAPANTHER:PTN002680016 and UniProtKB:Q17R892290270 GO_CentralGO_REF:0000033
Arhgap44Mouseplasma membrane is_active_inIBAPANTHER:PTN001797409 more ...2290270 GO_CentralGO_REF:0000033
Arhgap44Mousepostsynapse located_inISOArhgap44 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Arhgap44Mousepostsynapse  ISOArhgap44 (Rattus norvegicus)9068941MMO:0000110 ex vivo electron microscopyRGDPMID:23739967 and REF_RGD_ID:12050108
Arhgap44Mousepostsynaptic density is_active_inISOArhgap44 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Arhgap44Mousepostsynaptic density is_active_inIBAPANTHER:PTN002680016 and Arhgap44 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000033
Arhgap44Mousepostsynaptic density located_inISOArhgap44 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Arhgap44Mousepostsynaptic density located_inIEAUniProtKB:F1LQX4 and ensembl:ENSRNOP000000965462290270 EnsemblGO_REF:0000107
Arhgap44Mousepresynapse located_inISOArhgap44 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Arhgap44Mousepresynapse  ISOArhgap44 (Rattus norvegicus)9068941MMO:0000110 ex vivo electron microscopyRGDPMID:23739967 and REF_RGD_ID:12050108
1 to 20 of 25 rows

Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows


1 to 9 of 9 rows
#
Reference Title
Reference Citation
1. Screening low-frequency SNPS from genome-wide association study reveals a new risk allele for progression to AIDS. Le Clerc S, etal., J Acquir Immune Defic Syndr. 2011 Mar 1;56(3):279-84. doi: 10.1097/QAI.0b013e318204982b.
2. Genetic variants in the genes encoding rho GTPases and related regulators predict cutaneous melanoma-specific survival. Liu S, etal., Int J Cancer. 2017 Aug 15;141(4):721-730. doi: 10.1002/ijc.30785. Epub 2017 Jun 1.
3. A comprehensive landscape of transcription profiles and data resources for human leukemia. Luo M, etal., Blood Adv. 2023 Jul 25;7(14):3435-3449. doi: 10.1182/bloodadvances.2022008410.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. RICH2 is implicated in viraemic control of HIV-1 in black South African individuals. Paximadis M, etal., Infect Genet Evol. 2017 Apr;49:78-87. doi: 10.1016/j.meegid.2017.01.007. Epub 2017 Jan 6.
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Mutant p53 promotes cell spreading and migration via ARHGAP44. Xu J, etal., Sci China Life Sci. 2017 Sep;60(9):1019-1029. doi: 10.1007/s11427-016-9040-8. Epub 2017 May 16.
9. RICH2, a potential tumor suppressor in hepatocellular carcinoma. Zhang J, etal., Front Biosci (Landmark Ed). 2019 Jun 1;24(8):1363-1376. doi: 10.2741/4784.
1 to 9 of 9 rows
PMID:8889548   PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:11431473   PMID:12466851   PMID:12477932   PMID:12520002   PMID:14610273  
PMID:15489334   PMID:16141072   PMID:16141073   PMID:16512683   PMID:16602821   PMID:21267068   PMID:21873635   PMID:23739967   PMID:24352656   PMID:26969129   PMID:28642683   PMID:28671696  
PMID:32325033   PMID:37142655   PMID:37926169   PMID:38355793  



Arhgap44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391164,892,865 - 65,053,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1164,892,865 - 65,053,787 (-)EnsemblGRCm39 Ensembl
GRCm381165,002,039 - 65,162,972 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,002,039 - 65,162,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv371164,815,541 - 64,976,463 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361164,818,234 - 64,979,156 (-)NCBIMGSCv36mm8
Celera1171,938,015 - 72,099,074 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.42NCBI
ARHGAP44
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381712,789,498 - 12,991,643 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1712,789,498 - 12,991,643 (+)EnsemblGRCh38hg38GRCh38
GRCh371712,692,815 - 12,894,960 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361712,633,554 - 12,835,685 (+)NCBINCBI36Build 36hg18NCBI36
Celera1712,718,166 - 12,920,275 (+)NCBICelera
Cytogenetic Map17p12NCBI
HuRef1712,588,245 - 12,790,668 (+)NCBIHuRef
CHM1_11712,701,589 - 12,903,719 (+)NCBICHM1_1
T2T-CHM13v2.01712,696,985 - 12,899,110 (+)NCBIT2T-CHM13v2.0
Arhgap44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81050,154,724 - 50,322,027 (-)NCBIGRCr8
mRatBN7.21049,655,583 - 49,822,876 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1049,655,584 - 49,824,297 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01051,501,547 - 51,669,546 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1051,502,894 - 51,669,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01051,259,533 - 51,425,933 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41051,313,035 - 51,479,556 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11051,328,436 - 51,494,957 (-)NCBI
Celera1048,871,532 - 49,038,827 (-)NCBICelera
Cytogenetic Map10q24NCBI
Arhgap44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554674,430,087 - 4,522,611 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554674,428,738 - 4,590,877 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP44
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21960,757,445 - 60,959,269 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11765,564,061 - 65,765,878 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01738,657,824 - 38,859,591 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11743,357,438 - 43,558,355 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1743,357,438 - 43,453,457 (-)Ensemblpanpan1.1panPan2
ARHGAP44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1536,790,059 - 36,957,932 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl536,789,814 - 36,957,411 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha536,933,812 - 37,101,416 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0536,898,675 - 37,066,421 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl536,898,649 - 37,066,421 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1536,871,586 - 37,039,378 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0536,818,449 - 36,986,578 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0537,008,878 - 37,176,525 (+)NCBIUU_Cfam_GSD_1.0
Arhgap44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560251,899,406 - 52,068,726 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365955,373,476 - 5,543,073 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365955,373,645 - 5,542,915 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1257,049,895 - 57,206,889 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11257,049,900 - 57,206,706 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21260,167,786 - 60,195,211 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11612,125,543 - 12,328,203 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1612,125,574 - 12,330,501 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660598,910,762 - 9,113,230 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap44
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624877661,998 - 850,431 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624877662,595 - 851,762 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Arhgap44
6351 total Variants

Predicted Target Of
Summary Value
Count of predictions:2558
Count of miRNA genes:625
Interacting mature miRNAs:776
Transcripts:ENSMUST00000047463, ENSMUST00000093001, ENSMUST00000093002, ENSMUST00000130420
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 62 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse

1 to 10 of 62 rows
AI840762  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,021,796 - 65,021,897UniSTSGRCm38
MGSCv371164,835,298 - 64,835,399UniSTSGRCm37
Celera1171,957,772 - 71,957,873UniSTS
Cytogenetic Map11B3UniSTS
Whitehead/MRC_RH11851.8UniSTS
AU040829  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,002,124 - 65,002,233UniSTSGRCm38
MGSCv371164,815,626 - 64,815,735UniSTSGRCm37
Celera1171,938,100 - 71,938,209UniSTS
Cytogenetic Map11B3UniSTS
cM Map1131.0UniSTS
Whitehead/MRC_RH11851.05UniSTS
Whitehead/MRC_RH11852.61UniSTS
RH124888  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,001,737 - 65,001,853UniSTSGRCm38
MGSCv371164,815,239 - 64,815,355UniSTSGRCm37
Celera1171,937,713 - 71,937,829UniSTS
Cytogenetic Map11B3UniSTS
cM Map1131.0UniSTS
UniSTS:236614  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,002,164 - 65,002,392UniSTSGRCm38
MGSCv371164,815,666 - 64,815,894UniSTSGRCm37
Celera1171,938,140 - 71,938,368UniSTS
Cytogenetic Map11B3UniSTS
cM Map1131.0UniSTS
RH138269  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,151,957 - 65,152,084UniSTSGRCm38
MGSCv371164,965,459 - 64,965,586UniSTSGRCm37
Celera1172,087,982 - 72,088,109UniSTS
Cytogenetic Map11B3UniSTS
UniSTS:224505  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,013,818 - 65,013,975UniSTSGRCm38
MGSCv371164,827,320 - 64,827,477UniSTSGRCm37
Celera1171,949,794 - 71,949,951UniSTS
Cytogenetic Map11B3UniSTS
RH125885  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,001,801 - 65,002,052UniSTSGRCm38
MGSCv371164,815,303 - 64,815,554UniSTSGRCm37
Celera1171,937,777 - 71,938,028UniSTS
Cytogenetic Map11B3UniSTS
cM Map1131.0UniSTS
Whitehead/MRC_RH11848.76UniSTS






1 to 16 of 16 rows
RefSeq Transcripts NM_001099288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK032008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL663045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ059392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 16 of 16 rows

Ensembl Acc Id: ENSMUST00000047463   ⟹   ENSMUSP00000039139
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1164,892,865 - 65,053,787 (-)Ensembl
GRCm38.p6 Ensembl1165,002,039 - 65,162,961 (-)Ensembl
Ensembl Acc Id: ENSMUST00000093001   ⟹   ENSMUSP00000090680
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1164,942,301 - 65,053,393 (-)Ensembl
GRCm38.p6 Ensembl1165,051,475 - 65,162,567 (-)Ensembl
Ensembl Acc Id: ENSMUST00000093002   ⟹   ENSMUSP00000090681
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1164,892,866 - 65,053,730 (-)Ensembl
GRCm38.p6 Ensembl1165,002,040 - 65,162,904 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130420   ⟹   ENSMUSP00000115612
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1164,892,867 - 64,950,660 (-)Ensembl
GRCm38.p6 Ensembl1165,002,041 - 65,059,834 (-)Ensembl
RefSeq Acc Id: NM_001099288   ⟹   NP_001092758
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
GRCm381165,002,039 - 65,162,961 (-)NCBI
MGSCv371164,815,541 - 64,976,463 (-)RGD
Celera1171,938,015 - 72,099,074 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001408223   ⟹   NP_001395152
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
RefSeq Acc Id: NM_001408224   ⟹   NP_001395153
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
RefSeq Acc Id: NM_001408226   ⟹   NP_001395155
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
RefSeq Acc Id: NM_001408228   ⟹   NP_001395157
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
RefSeq Acc Id: NM_175003   ⟹   NP_778168
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,865 - 65,053,779 (-)NCBI
GRCm381165,002,039 - 65,162,961 (-)NCBI
MGSCv371164,815,541 - 64,976,463 (-)RGD
Celera1171,938,015 - 72,099,074 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532874   ⟹   XP_006532937
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,871 - 64,957,313 (-)NCBI
GRCm381165,002,039 - 65,066,514 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245812   ⟹   XP_030101672
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391164,892,871 - 65,053,104 (-)NCBI
GRCm381165,002,039 - 65,162,278 (-)NCBI
Sequence:
1 to 5 of 12 rows
1 to 5 of 12 rows
RefSeq Acc Id: NP_778168   ⟸   NM_175003
- Peptide Label: isoform 2
- UniProtKB: F6T1Y2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001092758   ⟸   NM_001099288
- Peptide Label: isoform 1
- UniProtKB: Q5SSM3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532937   ⟸   XM_006532874
- Peptide Label: isoform X4
- UniProtKB: F6T1Y2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101672   ⟸   XM_030245812
- Peptide Label: isoform X4
- UniProtKB: F6T1Y2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000115612   ⟸   ENSMUST00000130420
BAR   Rho-GAP

Name Modeler Protein Id AA Range Protein Structure
AF-Q5SSM3-F1-model_v2 AlphaFold Q5SSM3 1-814 view protein structure

RGD ID:6820474
Promoter ID:MM_KWN:7892
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000093002,   ENSMUST00000093003,   NM_001099288,   NM_175003,   OTTMUST00000013122
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361164,976,076 - 64,976,576 (-)MPROMDB
RGD ID:8675036
Promoter ID:EPDNEW_M15549
Type:initiation region
Name:Arhgap44_1
Description:Mus musculus Rho GTPase activating protein 44 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381165,162,937 - 65,162,997EPDNEW


1 to 40 of 42 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000033389 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000047463 ENTREZGENE
  ENSMUST00000047463.15 UniProtKB/Swiss-Prot
  ENSMUST00000093001.5 UniProtKB/Swiss-Prot
  ENSMUST00000093002 ENTREZGENE
  ENSMUST00000093002.12 UniProtKB/Swiss-Prot
  ENSMUST00000130420 ENTREZGENE
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot
  1.20.1270.60 UniProtKB/Swiss-Prot
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot
  BAR_dom UniProtKB/Swiss-Prot
  RHG17/44/SH3BP1-like UniProtKB/Swiss-Prot
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot
  RhoGAP_dom UniProtKB/Swiss-Prot
KEGG Report mmu:216831 UniProtKB/Swiss-Prot
MGD MGI:2144423 ENTREZGENE
NCBI Gene Arhgap44 ENTREZGENE
PANTHER 3BP-1 RELATED RHOGAP UniProtKB/Swiss-Prot
  RHO GTPASE-ACTIVATING PROTEIN 44 UniProtKB/Swiss-Prot
Pfam BAR UniProtKB/Swiss-Prot
  RhoGAP UniProtKB/Swiss-Prot
PhenoGen Arhgap44 PhenoGen
PROSITE BAR UniProtKB/Swiss-Prot
  RHOGAP UniProtKB/Swiss-Prot
SMART BAR UniProtKB/Swiss-Prot
  RhoGAP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot
  SSF48350 UniProtKB/Swiss-Prot
UniProt F6T1Y2 ENTREZGENE, UniProtKB/TrEMBL
  Q5SSM3 ENTREZGENE
  Q5SSM4 ENTREZGENE
  Q5SSM6 ENTREZGENE
  Q5SSM7 ENTREZGENE
  Q7TNB9 ENTREZGENE
  Q8BW90 ENTREZGENE
  Q8C090_MOUSE UniProtKB/TrEMBL
  RHG44_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q5SSM4 UniProtKB/Swiss-Prot
  Q5SSM6 UniProtKB/Swiss-Prot
  Q5SSM7 UniProtKB/Swiss-Prot
1 to 40 of 42 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Arhgap44  Rho GTPase activating protein 44  AU040829  expressed sequence AU040829  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 AU040829  expressed sequence AU040829  Arhgap44  Rho GTPase activating protein 44  Symbol and/or name change 5135510 APPROVED
2011-07-27 Arhgap44  Rho GTPase activating protein 44  AU040829  expressed sequence AU040829  Symbol and/or name change 5135510 APPROVED