Parp2 (poly (ADP-ribose) polymerase family, member 2) - Rat Genome Database

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Gene: Parp2 (poly (ADP-ribose) polymerase family, member 2) Mus musculus
Analyze
Symbol: Parp2
Name: poly (ADP-ribose) polymerase family, member 2
RGD ID: 1553525
MGI Page MGI
Description: Enables NAD+ ADP-ribosyltransferase activity. Involved in decidualization. Acts upstream of or within base-excision repair and extrinsic apoptotic signaling pathway. Located in nucleolus and nucleoplasm. Is expressed in several structures, including central nervous system; gonad; liver; retina; and thymus. Orthologous to human PARP2 (poly(ADP-ribose) polymerase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Adp; ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 2; ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase diphtheria toxin-like 2; ADPRT-2; Adprt2; Adprtl2; ARTD2; As; Aspartl2; C78626; DNA ADP-ribosyltransferase PARP2; mPARP-2; NAD(+) ADP-ribosyltransferase 2; PA; pADPRT-2; PARP-2; poly [ADP-ribose] polymerase 2; poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,045,347 - 51,058,758 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,045,298 - 51,058,758 (+)EnsemblGRCm39 Ensembl
GRCm381450,807,897 - 50,821,301 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,807,841 - 50,821,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv371451,427,621 - 51,440,975 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361449,729,897 - 49,743,251 (+)NCBIMGSCv36mm8
Celera1447,099,033 - 47,112,197 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IEA)
nucleolus  (IBA,IDA,ISO)
nucleoplasm  (IDA,ISO)
nucleus  (IDA,ISO)
site of DNA damage  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation. Barkauskaite E, etal., Mol Cell. 2015 Jun 18;58(6):935-46. doi: 10.1016/j.molcel.2015.05.007.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1. Zhang L, etal., Eur J Pharmacol. 2014 Dec 5;744:203-10. doi: 10.1016/j.ejphar.2014.09.037. Epub 2014 Sep 30.
Additional References at PubMed
PMID:10338144   PMID:10349636   PMID:10364231   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11133988   PMID:11217851   PMID:11948190   PMID:12065591   PMID:12477932   PMID:12727891  
PMID:14610273   PMID:14739238   PMID:14749375   PMID:15279798   PMID:15489334   PMID:15615785   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16946705   PMID:17001008   PMID:17470554  
PMID:17784788   PMID:17951580   PMID:17982172   PMID:18436469   PMID:19364882   PMID:19422384   PMID:19607827   PMID:20154718   PMID:20236222   PMID:20613774   PMID:20634404   PMID:21228215  
PMID:21398629   PMID:21459329   PMID:21677750   PMID:21873635   PMID:21921080   PMID:22751932   PMID:22941645   PMID:23209382   PMID:23357680   PMID:23607899   PMID:23678004   PMID:24365238  
PMID:25501596   PMID:26110280   PMID:26432600   PMID:26687988   PMID:26700152   PMID:27373144   PMID:27847302   PMID:28177129   PMID:28181505   PMID:28751426   PMID:29361132   PMID:30077797  
PMID:30104678   PMID:30996287   PMID:32001817   PMID:32046043   PMID:32098917   PMID:32221289   PMID:32325033   PMID:32633392   PMID:32679243   PMID:34051087   PMID:34359075   PMID:34580230  
PMID:34732825   PMID:37188809   PMID:37351597   PMID:37457706   PMID:38481797  


Genomics

Comparative Map Data
Parp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,045,347 - 51,058,758 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,045,298 - 51,058,758 (+)EnsemblGRCm39 Ensembl
GRCm381450,807,897 - 50,821,301 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,807,841 - 50,821,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv371451,427,621 - 51,440,975 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361449,729,897 - 49,743,251 (+)NCBIMGSCv36mm8
Celera1447,099,033 - 47,112,197 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.25NCBI
PARP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,343,635 - 20,357,904 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,343,615 - 20,357,904 (+)EnsemblGRCh38hg38GRCh38
GRCh371420,811,794 - 20,826,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361419,881,613 - 19,895,903 (+)NCBINCBI36Build 36hg18NCBI36
Celera14672,919 - 687,220 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef14933,616 - 947,915 (+)NCBIHuRef
CHM1_11420,813,199 - 20,827,472 (+)NCBICHM1_1
T2T-CHM13v2.01414,540,530 - 14,554,811 (+)NCBIT2T-CHM13v2.0
Parp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,494,722 - 26,517,893 (+)NCBIGRCr8
mRatBN7.21524,034,069 - 24,044,340 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,034,106 - 24,044,338 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1526,805,300 - 26,815,532 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,764,036 - 27,774,257 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,013,838 - 26,024,070 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,739,416 - 27,749,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,739,251 - 27,749,648 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01531,571,841 - 31,582,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41526,790,296 - 26,801,086 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11526,806,027 - 26,816,785 (+)NCBI
Celera1524,353,597 - 24,363,829 (+)NCBICelera
Cytogenetic Map15p14NCBI
Parp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,140,460 - 1,151,491 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,138,976 - 1,152,293 (+)NCBIChiLan1.0ChiLan1.0
PARP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21521,850,677 - 21,864,950 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,067,164 - 21,081,440 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,215,727 - 1,230,006 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,268,986 - 19,282,960 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,269,046 - 19,282,853 (+)Ensemblpanpan1.1panPan2
PARP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,705,966 - 17,716,743 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,705,975 - 17,716,094 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,191,050 - 18,201,770 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01517,964,896 - 17,975,837 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1517,964,862 - 17,975,138 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,647,938 - 17,657,915 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,702,653 - 17,713,344 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01517,831,425 - 17,842,255 (+)NCBIUU_Cfam_GSD_1.0
Parp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864077,573,779 - 77,583,748 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936877554,473 - 564,903 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936877554,969 - 564,905 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,535,076 - 78,551,375 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,535,072 - 78,551,393 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,563,415 - 83,579,720 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PARP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12920,862,787 - 20,877,752 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2920,863,380 - 20,877,644 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605925,544,206 - 25,558,652 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Parp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248254,313,217 - 4,325,968 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248254,312,243 - 4,326,058 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Parp2
506 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:22
Count of miRNA genes:18
Interacting mature miRNAs:22
Transcripts:ENSMUST00000036126
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142792195761137449Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142999699463997133Mouse
27226744Metcl6_mmetatarsal-calcaneal length 6, 5 week (mouse)143032195752937457Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143033525064335381Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143033525064335381Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143322195759437449Mouse
27226727Tibl21_mtibia length 21, 16 week (mouse)143412195752937457Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
4141484Hcbip1_mhexachlorobenzene induced porphyria 1 (mouse)Not determined4733525059962593Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse

Markers in Region
UniSTS:492996  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381450,807,447 - 50,807,771UniSTSGRCm38
MGSCv371451,427,122 - 51,427,446UniSTSGRCm37
Celera1447,098,555 - 47,098,858UniSTS
Cytogenetic Map14C1UniSTS
cM Map1419.5UniSTS
RH126406  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381450,820,831 - 50,821,179UniSTSGRCm38
MGSCv371451,440,506 - 51,440,854UniSTSGRCm37
Celera1447,111,728 - 47,112,076UniSTS
Cytogenetic Map14C1UniSTS
cM Map1419.5UniSTS
Whitehead/MRC_RH14579.46UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001422083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001422084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001422085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_185484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_185485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC027184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF072521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF191547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ007780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000036126   ⟹   ENSMUSP00000048877
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1451,045,298 - 51,058,758 (+)Ensembl
GRCm38.p6 Ensembl1450,807,841 - 50,821,301 (+)Ensembl
RefSeq Acc Id: ENSMUST00000226880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1451,045,382 - 51,053,756 (+)Ensembl
GRCm38.p6 Ensembl1450,807,925 - 50,816,299 (+)Ensembl
RefSeq Acc Id: ENSMUST00000227705
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1451,045,383 - 51,048,027 (+)Ensembl
GRCm38.p6 Ensembl1450,807,926 - 50,810,570 (+)Ensembl
RefSeq Acc Id: ENSMUST00000227810   ⟹   ENSMUSP00000153963
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1451,052,327 - 51,056,928 (+)Ensembl
GRCm38.p6 Ensembl1450,814,870 - 50,819,471 (+)Ensembl
RefSeq Acc Id: ENSMUST00000228624
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1451,056,365 - 51,056,947 (+)Ensembl
GRCm38.p6 Ensembl1450,818,908 - 50,819,490 (+)Ensembl
RefSeq Acc Id: ENSMUST00000228672
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1451,045,403 - 51,058,757 (+)Ensembl
GRCm38.p6 Ensembl1450,807,946 - 50,821,300 (+)Ensembl
RefSeq Acc Id: ENSMUST00000228833
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1451,056,802 - 51,057,193 (+)Ensembl
GRCm38.p6 Ensembl1450,819,345 - 50,819,736 (+)Ensembl
RefSeq Acc Id: ENSMUST00000228872
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1451,057,736 - 51,058,376 (+)Ensembl
GRCm38.p6 Ensembl1450,820,279 - 50,820,919 (+)Ensembl
RefSeq Acc Id: NM_001422083   ⟹   NP_001409012
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391451,045,382 - 51,058,758 (+)NCBI
RefSeq Acc Id: NM_001422084   ⟹   NP_001409013
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391451,045,382 - 51,058,758 (+)NCBI
RefSeq Acc Id: NM_001422085   ⟹   NP_001409014
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391451,045,382 - 51,058,758 (+)NCBI
RefSeq Acc Id: NM_009632   ⟹   NP_033762
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391451,045,382 - 51,058,758 (+)NCBI
GRCm381450,807,916 - 50,821,301 (+)NCBI
MGSCv371451,427,621 - 51,440,975 (+)RGD
Celera1447,099,033 - 47,112,197 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_185484
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391451,045,382 - 51,058,758 (+)NCBI
RefSeq Acc Id: NR_185485
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391451,045,382 - 51,058,758 (+)NCBI
RefSeq Acc Id: XM_036158400   ⟹   XP_036014293
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391451,045,347 - 51,058,758 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033762   ⟸   NM_009632
- Peptide Label: isoform 1
- UniProtKB: Q99N29 (UniProtKB/Swiss-Prot),   O88554 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000153963   ⟸   ENSMUST00000227810
RefSeq Acc Id: ENSMUSP00000048877   ⟸   ENSMUST00000036126
RefSeq Acc Id: XP_036014293   ⟸   XM_036158400
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001409014   ⟸   NM_001422085
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001409013   ⟸   NM_001422084
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001409012   ⟸   NM_001422083
- Peptide Label: isoform 2
Protein Domains
PARP alpha-helical   PARP catalytic   WGR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88554-F1-model_v2 AlphaFold O88554 1-559 view protein structure

Promoters
RGD ID:8682124
Promoter ID:EPDNEW_M19093
Type:multiple initiation site
Name:Parp2_1
Description:Mus musculus poly (ADP-ribose) polymerase family, member 2 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381450,807,925 - 50,807,985EPDNEW
RGD ID:6825253
Promoter ID:MM_KWN:16560
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000036126,   NR_002142,   UC007TLR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361451,427,186 - 51,427,686 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1341112 AgrOrtholog
Ensembl Genes ENSMUSG00000036023 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000036126 ENTREZGENE
  ENSMUST00000036126.7 UniProtKB/Swiss-Prot
  ENSMUST00000227810.2 UniProtKB/TrEMBL
  ENSMUST00000228672 ENTREZGENE
Gene3D-CATH 1.20.142.10 UniProtKB/Swiss-Prot
  3.90.228.10 UniProtKB/Swiss-Prot
  WGR domain UniProtKB/Swiss-Prot
InterPro Poly(ADP-ribose)pol_cat_dom UniProtKB/Swiss-Prot
  Poly(ADP-ribose)pol_reg_dom UniProtKB/Swiss-Prot
  Poly(ADP-ribose)pol_reg_dom_sf UniProtKB/Swiss-Prot
  WGR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WGR_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11546 UniProtKB/Swiss-Prot
MGD MGI:1341112 ENTREZGENE
NCBI Gene 11546 ENTREZGENE
PANTHER DNA LIGASE UniProtKB/Swiss-Prot
  POLY [ADP-RIBOSE] POLYMERASE 2 UniProtKB/Swiss-Prot
Pfam PARP UniProtKB/Swiss-Prot
  PARP_reg UniProtKB/Swiss-Prot
  WGR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Parp2 PhenoGen
PROSITE PARP_ALPHA_HD UniProtKB/Swiss-Prot
  PARP_CATALYTIC UniProtKB/Swiss-Prot
  WGR UniProtKB/Swiss-Prot
SMART WGR UniProtKB/Swiss-Prot
Superfamily-SCOP ADP-ribosylation UniProtKB/Swiss-Prot
  SSF142921 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47587 UniProtKB/Swiss-Prot
UniProt A0A2I3BPY1_MOUSE UniProtKB/TrEMBL
  O88554 ENTREZGENE, UniProtKB/Swiss-Prot
  Q99N29 ENTREZGENE
UniProt Secondary Q99N29 UniProtKB/Swiss-Prot